[Hub]/) : Traits : Arm fat mass (right) :

chr9:14,857,740-16,758,776

Best TWAS P=1.66e-22 · Best GWAS P=2.64e-18 conditioned to 0.845

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Aorta CCDC171 0.18 0.05 lasso 5 0.08 2.2e-05 -4.0 -5.5 3.8e-08 0.32 0.33 0.07 FALSE
2 GTEx Artery Tibial CCDC171 0.10 0.09 enet 9 0.12 7.2e-10 4.3 -5.9 3.1e-09 0.63 0.81 0.19 FALSE
3 GTEx Brain Caudate basal ganglia CCDC171 0.30 0.18 lasso 4 0.23 2.4e-07 8.0 -8.6 1.0e-17 0.95 0.10 0.90 FALSE
4 GTEx Brain Cerebellar Hemisphere CCDC171 0.46 0.19 lasso 7 0.23 1.3e-06 -8.5 -9.8 1.7e-22 0.88 0.16 0.81 TRUE
5 GTEx Brain Cerebellum CCDC171 0.46 0.22 lasso 7 0.15 3.4e-05 -8.6 -9.0 2.9e-19 0.97 0.06 0.94 FALSE
6 GTEx Brain Cortex CCDC171 0.26 0.15 lasso 2 0.16 2.8e-05 -6.9 -7.9 2.5e-15 0.91 0.16 0.76 FALSE
7 GTEx Brain Frontal Cortex BA9 CCDC171 0.27 0.18 enet 10 0.19 8.3e-06 8.0 -8.0 1.7e-15 0.86 0.09 0.84 FALSE
8 GTEx Brain Hypothalamus CCDC171 0.32 0.17 enet 6 0.09 4.0e-03 -8.5 -7.4 1.5e-13 0.89 0.11 0.64 FALSE
9 GTEx Breast Mammary Tissue CCDC171 0.21 0.01 lasso 5 0.03 1.5e-02 7.2 -5.2 2.3e-07 0.55 0.34 0.26 FALSE
10 GTEx Lung CCDC171 0.13 0.03 enet 9 0.01 5.0e-02 5.2 -6.9 3.7e-12 0.71 0.38 0.40 FALSE
11 GTEx Nerve Tibial CCDC171 0.25 0.16 lasso 6 0.14 2.1e-10 -8.4 -8.4 4.4e-17 0.96 0.14 0.86 FALSE
12 GTEx Ovary CCDC171 0.21 0.19 lasso 4 0.16 7.7e-05 7.6 7.4 1.7e-13 -0.88 0.13 0.59 FALSE
13 GTEx Pituitary CCDC171 0.28 0.16 enet 29 0.12 5.2e-04 7.8 -8.3 1.4e-16 0.91 0.25 0.66 FALSE
14 GTEx Skin Not Sun Exposed Suprapubic CCDC171 0.20 0.04 enet 45 0.06 4.9e-04 8.0 -5.2 2.1e-07 0.41 0.63 0.26 FALSE
15 GTEx Skin Sun Exposed Lower leg CCDC171 0.14 0.09 enet 13 0.12 1.9e-10 7.6 -6.2 4.5e-10 0.64 0.92 0.08 FALSE
16 METSIM Adipose CCDC171 0.03 0.00 blup 828 0.01 4.0e-02 7.9 -7.4 1.8e-13 0.81 0.21 0.56 FALSE
17 ROSMAP Brain Pre-frontal Cortex CCDC171 0.14 0.11 enet 21 0.11 8.3e-14 8.2 -8.2 2.0e-16 0.83 0.69 0.31 FALSE
18 The Cancer Genome Atlas Soft Tissue Sarcoma C9orf93 0.06 0.05 lasso 3 0.03 5.3e-03 7.2 -6.3 2.4e-10 0.70 0.13 0.28 FALSE