[Hub]/) : Traits : Arm fat-free mass (right) :

chr6:160,071,844-161,571,560

Best TWAS P=1e-11 · Best GWAS P=2.17e-15 conditioned to 1.11e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum SLC22A3 0.13 0.06 enet 7 0.09 1.3e-05 -5.3 -5.5 4.0e-08 -0.63 0.53 0.46 FALSE
2 GTEx Brain Caudate basal ganglia SLC22A3 0.15 0.10 enet 39 0.11 5.6e-04 -6.7 -6.8 1.0e-11 -0.71 0.05 0.88 TRUE
3 GTEx Brain Frontal Cortex BA9 SLC22A3 0.26 0.08 lasso 6 0.05 1.5e-02 -3.9 -5.5 3.2e-08 -0.63 0.15 0.59 FALSE
4 GTEx Esophagus Mucosa SLC22A3 0.19 0.08 enet 47 0.12 1.7e-08 5.4 -6.3 3.3e-10 -0.58 0.64 0.36 FALSE
5 GTEx Nerve Tibial SLC22A3 0.20 0.10 lasso 7 0.13 3.2e-09 -5.2 -5.6 2.5e-08 -0.56 0.99 0.00 FALSE
6 GTEx Ovary SLC22A3 0.33 0.29 lasso 6 0.23 2.8e-06 -5.1 -5.3 1.1e-07 -0.65 0.12 0.79 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic SLC22A3 0.15 0.05 lasso 9 0.05 9.9e-04 -3.2 -5.6 1.7e-08 -0.65 0.11 0.86 FALSE
8 GTEx Testis SLC22A3 0.19 0.01 lasso 14 0.05 2.6e-03 -7.6 -5.4 6.6e-08 -0.66 0.14 0.84 FALSE
9 ROSMAP Brain Pre-frontal Cortex SLC22A3 0.14 0.20 lasso 10 0.19 2.4e-24 -5.4 -5.7 1.2e-08 -0.67 1.00 0.00 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma LPAL2 0.07 0.00 blup 74 0.04 1.1e-03 -3.6 5.6 2.3e-08 0.75 0.04 0.51 FALSE