Best TWAS P=1.72e-15 · Best GWAS P=4.51e-16 conditioned to 0.00471
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Mucosa | CCDC126 | 0.12 | 0.03 | lasso | 7 | 0.01 | 0.043 | -6.8 | 6.2 | 5.5e-10 | -0.51 | 0.08 | 0.61 | FALSE |
2 | The Cancer Genome Atlas | Esophageal Carcinoma | TRA2A | 0.18 | 0.02 | blup | 40 | 0.05 | 0.012 | -7.8 | -8.0 | 1.7e-15 | 0.81 | 0.01 | 0.42 | TRUE |
3 | The Cancer Genome Atlas | Soft Tissue Sarcoma | RPS2P32 | 0.08 | 0.02 | blup | 27 | 0.02 | 0.031 | -5.1 | 5.7 | 1.4e-08 | -0.46 | 0.03 | 0.23 | FALSE |