[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr7:70,996,097-73,789,730

Best TWAS P=2.87e-18 · Best GWAS P=1.09e-17 conditioned to 0.0267

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
14	GTEx	Thyroid	MLXIPL	0.23	0.14	lasso	7	0.15	2.1e-11	7.58	8.7	2.9e-18	0.83	0.02	0.98	TRUE
21	The Cancer Genome Atlas	Skin Cutaneous Melanoma	CALN1	0.37	0.04	enet	10	0.25	3.1e-07	-6.22	5.2	2.1e-07	0.02	0.01	0.96	TRUE
6	GTEx	Cells Transformed fibroblasts	MLXIPL	0.13	0.06	enet	6	0.09	2.2e-07	8.42	8.7	3.2e-18	0.82	0.02	0.98	FALSE
16	METSIM	Adipose	MLXIPL	0.12	0.14	lasso	4	0.13	1.8e-19	8.28	8.7	4.5e-18	0.80	0.04	0.96	FALSE
2	GTEx	Adipose Subcutaneous	MLXIPL	0.11	0.07	enet	16	0.07	1.6e-06	7.58	8.5	2.2e-17	0.88	0.03	0.97	FALSE
10	GTEx	Skin Sun Exposed Lower leg	MLXIPL	0.12	0.09	lasso	4	0.06	6.1e-06	8.37	8.4	3.5e-17	0.86	0.03	0.97	FALSE
19	The Cancer Genome Atlas	Lung Adenocarcinoma	MLXIPL	0.04	0.03	lasso	1	0.02	2.3e-03	8.34	8.3	7.2e-17	0.67	0.00	0.97	FALSE
9	GTEx	Skin Not Sun Exposed Suprapubic	MLXIPL	0.11	0.11	lasso	3	0.06	2.7e-04	8.42	8.3	1.3e-16	0.84	0.02	0.97	FALSE
3	GTEx	Adipose Visceral Omentum	MLXIPL	0.16	0.02	lasso	3	0.03	7.8e-03	7.79	8.3	1.5e-16	0.81	0.14	0.84	FALSE
11	GTEx	Spleen	NCF1B	0.22	0.10	enet	9	0.08	5.1e-03	8.02	-8.2	1.6e-16	-0.62	0.03	0.53	FALSE
17	The Cancer Genome Atlas	Breast Invasive Carcinoma	MLXIPL	0.06	0.05	lasso	2	0.05	5.1e-10	8.34	8.0	1.3e-15	0.67	0.00	1.00	FALSE
12	GTEx	Testis	MLXIPL	0.10	0.00	lasso	3	0.00	3.3e-01	5.62	7.6	4.1e-14	0.66	0.04	0.35	FALSE
4	GTEx	Adipose Visceral Omentum	NSUN5	0.07	0.03	enet	11	0.04	4.0e-03	8.34	7.3	2.3e-13	0.71	0.02	0.77	FALSE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	MLXIPL	0.08	0.05	enet	4	0.05	5.3e-06	8.34	7.2	6.4e-13	0.64	0.00	1.00	FALSE
22	The Cancer Genome Atlas	Thyroid Carcinoma	BCL7B	0.05	0.01	blup	5	0.03	1.3e-03	8.34	-7.1	1.2e-12	-0.38	0.00	0.63	FALSE
8	GTEx	Lung	MLXIPL	0.10	0.07	enet	14	0.07	6.3e-06	7.58	6.5	7.4e-11	0.65	0.09	0.78	FALSE
1	CommonMind	Brain Pre-frontal Cortex	DNAJC30	0.13	0.07	enet	32	0.07	2.7e-09	5.74	6.0	2.7e-09	0.24	1.00	0.00	FALSE
15	METSIM	Adipose	BCL7B	0.10	0.02	enet	20	0.05	1.2e-07	7.79	5.8	8.1e-09	0.66	0.02	0.98	FALSE
7	GTEx	Heart Left Ventricle	MLXIPL	0.14	0.00	enet	24	0.01	1.3e-01	0.36	5.7	1.6e-08	0.52	0.10	0.49	FALSE
13	GTEx	Testis	VPS37D	0.15	0.01	lasso	5	0.03	2.7e-02	-4.98	-5.4	8.1e-08	-0.24	0.13	0.06	FALSE
18	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	BCL7B	0.08	0.04	blup	5	0.06	1.0e-03	8.34	-5.3	1.2e-07	-0.35	0.00	0.90	FALSE
5	GTEx	Breast Mammary Tissue (Female)	TBL2	0.26	-0.01	enet	32	0.00	3.3e-01	2.19	-5.2	2.5e-07	-0.27	0.02	0.31	FALSE