Best TWAS P=5.35e-09 · Best GWAS P=4.43e-10 conditioned to 0.0265
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adrenal Gland | KCTD9 | 0.23 | -0.01 | lasso | 6 | 0.00 | 3.8e-01 | -5.2 | -5.2 | 1.7e-07 | 0.70 | 0.09 | 0.21 | FALSE |
| 2 | GTEx | Muscle Skeletal | KCTD9 | 0.11 | 0.07 | lasso | 5 | 0.06 | 7.9e-07 | -5.2 | -5.6 | 1.7e-08 | 0.85 | 0.12 | 0.87 | FALSE |
| 3 | YFS | Blood | KCTD9 | 0.04 | 0.04 | lasso | 8 | 0.04 | 7.8e-12 | -5.2 | 5.2 | 2.0e-07 | -0.66 | 0.85 | 0.15 | FALSE |
| 4 | The Cancer Genome Atlas | Lung Adenocarcinoma | KCTD9 | 0.03 | 0.01 | blup | 75 | 0.01 | 1.1e-02 | -6.0 | -5.8 | 5.3e-09 | 0.92 | 0.02 | 0.70 | TRUE |