Best TWAS P=5.71e-10 · Best GWAS P=9.36e-10 conditioned to 0.00417
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Whole Blood | CTNNAL1 | 0.14 | 0.07 | lasso | 6 | 0.07 | 9.4e-07 | 3.6 | 5.1 | 2.8e-07 | 0.10 | 0.15 | 0.79 | FALSE |
2 | The Cancer Genome Atlas | Prostate Adenocarcinoma | CTNNAL1 | 0.09 | 0.00 | blup | 83 | 0.04 | 1.0e-04 | 3.6 | 6.2 | 5.7e-10 | 0.63 | 0.03 | 0.36 | TRUE |