[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr9:126,321,003-128,824,378

Best TWAS P=8.55e-11 · Best GWAS P=1.42e-10 conditioned to 0.827

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Artery Tibial	GAPVD1	0.11	0.16	enet	19	0.16	6.4e-13	-6.0	-6.5	8.6e-11	0.94	0.02	0.98	TRUE
6	GTEx	Breast Mammary Tissue	PSMB7	0.11	0.03	lasso	7	0.04	4.7e-03	6.0	-5.9	4.7e-09	0.06	0.03	0.89	TRUE
19	GTEx	Thyroid	GAPVD1	0.05	0.05	enet	13	0.01	6.6e-02	-6.2	-6.5	9.7e-11	0.96	0.02	0.98	FALSE
24	The Cancer Genome Atlas	Prostate Adenocarcinoma	GAPVD1	0.02	0.04	enet	4	0.01	9.8e-03	-6.4	6.4	1.8e-10	-0.97	0.02	0.91	FALSE
14	GTEx	Muscle Skeletal	GAPVD1	0.13	0.10	lasso	3	0.09	4.7e-09	-6.3	6.3	2.4e-10	-0.95	0.02	0.98	FALSE
15	GTEx	Nerve Tibial	GAPVD1	0.17	0.08	lasso	10	0.10	9.3e-08	5.2	-6.3	3.1e-10	0.84	0.12	0.88	FALSE
13	GTEx	Esophagus Muscularis	OLFML2A	0.08	0.00	enet	27	0.00	4.9e-01	5.0	5.7	9.2e-09	-0.50	0.08	0.25	FALSE
5	GTEx	Brain Cerebellum	PRPS1P2	0.09	0.08	enet	16	0.04	2.8e-02	-6.3	5.6	1.8e-08	-0.84	0.05	0.79	FALSE
9	GTEx	Colon Sigmoid	PSMB7	0.15	0.10	lasso	3	0.09	3.3e-04	5.5	-5.6	2.0e-08	0.05	0.05	0.91	FALSE
2	GTEx	Adipose Subcutaneous	PSMB7	0.08	0.04	lasso	6	0.04	3.4e-04	4.4	-5.6	2.1e-08	0.02	0.03	0.97	FALSE
7	GTEx	Breast Mammary Tissue (Female)	PPP6C	0.14	0.04	lasso	4	0.04	3.1e-02	5.2	-5.5	3.0e-08	0.74	0.08	0.80	FALSE
28	The Cancer Genome Atlas	Thyroid Carcinoma	PSMB7	0.06	0.06	lasso	4	0.04	3.7e-05	5.5	-5.5	3.3e-08	0.07	0.08	0.92	FALSE
17	GTEx	Skin Sun Exposed Lower leg	GAPVD1	0.04	0.01	lasso	4	0.01	3.8e-02	5.2	-5.4	5.8e-08	0.77	0.21	0.68	FALSE
11	GTEx	Esophagus Mucosa	PPP6C	0.07	0.07	enet	21	0.08	7.1e-06	5.2	-5.4	6.8e-08	0.67	0.89	0.10	FALSE
12	GTEx	Esophagus Mucosa	PRPS1P2	0.07	0.08	lasso	3	0.07	1.5e-05	5.2	5.4	7.0e-08	-0.67	0.49	0.43	FALSE
10	GTEx	Colon Transverse	PRPS1P2	0.11	0.10	lasso	1	0.08	1.8e-04	5.3	5.3	9.2e-08	-0.68	0.60	0.10	FALSE
26	The Cancer Genome Atlas	Prostate Adenocarcinoma	PSMB7	0.03	0.04	lasso	4	0.04	1.2e-04	5.4	-5.3	9.5e-08	0.03	0.04	0.93	FALSE
16	GTEx	Pancreas	PRPS1P2	0.16	0.13	lasso	6	0.12	8.7e-06	5.2	5.3	1.2e-07	-0.67	0.81	0.16	FALSE
25	The Cancer Genome Atlas	Prostate Adenocarcinoma	PPP6C	0.06	0.08	lasso	7	0.07	1.8e-07	5.2	-5.3	1.4e-07	0.64	0.02	0.98	FALSE
18	GTEx	Thyroid	NEK6	0.20	0.21	lasso	4	0.20	1.3e-15	5.2	-5.3	1.5e-07	0.05	0.31	0.69	FALSE
20	GTEx	Thyroid	PRPS1P2	0.08	0.09	enet	18	0.07	4.0e-06	5.2	5.2	1.6e-07	-0.72	0.86	0.13	FALSE
22	The Cancer Genome Atlas	Brain Lower Grade Glioma	PPP6C	0.02	0.02	lasso	2	0.01	1.5e-02	5.3	-5.2	1.9e-07	0.68	0.02	0.69	FALSE
1	GTEx	Adipose Subcutaneous	PPP6C	0.06	0.10	lasso	3	0.07	3.2e-06	5.2	-5.2	2.0e-07	0.74	0.88	0.10	FALSE
23	The Cancer Genome Atlas	Lung Adenocarcinoma	PPP6C	0.02	0.02	lasso	4	0.02	7.6e-04	5.2	-5.2	2.0e-07	0.67	0.02	0.96	FALSE
4	GTEx	Artery Tibial	PRPS1P2	0.06	0.06	enet	6	0.05	9.2e-05	5.2	5.2	2.1e-07	-0.65	0.82	0.15	FALSE
27	The Cancer Genome Atlas	Thyroid Carcinoma	PPP6C	0.08	0.13	enet	9	0.13	5.5e-13	5.2	-5.2	2.1e-07	0.69	0.02	0.98	FALSE
8	GTEx	Cells Transformed fibroblasts	PRPS1P2	0.09	0.11	enet	8	0.13	9.6e-10	5.3	5.2	2.5e-07	-0.65	0.89	0.11	FALSE
21	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	PPP6C	0.07	0.08	lasso	3	0.09	5.4e-10	5.2	-5.2	2.5e-07	0.68	0.03	0.97	FALSE