[Hub]/) : Traits : Arm fat-free mass (right) :

chr9:126,321,003-128,824,378

Best TWAS P=8.55e-11 · Best GWAS P=1.42e-10 conditioned to 0.827

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous PPP6C 0.06 0.10 lasso 3 0.07 3.2e-06 5.2 -5.2 2.0e-07 0.74 0.88 0.10 FALSE
2 GTEx Adipose Subcutaneous PSMB7 0.08 0.04 lasso 6 0.04 3.4e-04 4.4 -5.6 2.1e-08 0.02 0.03 0.97 FALSE
3 GTEx Artery Tibial GAPVD1 0.11 0.16 enet 19 0.16 6.4e-13 -6.0 -6.5 8.6e-11 0.94 0.02 0.98 TRUE
4 GTEx Artery Tibial PRPS1P2 0.06 0.06 enet 6 0.05 9.2e-05 5.2 5.2 2.1e-07 -0.65 0.82 0.15 FALSE
5 GTEx Brain Cerebellum PRPS1P2 0.09 0.08 enet 16 0.04 2.8e-02 -6.3 5.6 1.8e-08 -0.84 0.05 0.79 FALSE
6 GTEx Breast Mammary Tissue PSMB7 0.11 0.03 lasso 7 0.04 4.7e-03 6.0 -5.9 4.7e-09 0.06 0.03 0.89 TRUE
7 GTEx Breast Mammary Tissue (Female) PPP6C 0.14 0.04 lasso 4 0.04 3.1e-02 5.2 -5.5 3.0e-08 0.74 0.08 0.80 FALSE
8 GTEx Cells Transformed fibroblasts PRPS1P2 0.09 0.11 enet 8 0.13 9.6e-10 5.3 5.2 2.5e-07 -0.65 0.89 0.11 FALSE
9 GTEx Colon Sigmoid PSMB7 0.15 0.10 lasso 3 0.09 3.3e-04 5.5 -5.6 2.0e-08 0.05 0.05 0.91 FALSE
10 GTEx Colon Transverse PRPS1P2 0.11 0.10 lasso 1 0.08 1.8e-04 5.3 5.3 9.2e-08 -0.68 0.60 0.10 FALSE
11 GTEx Esophagus Mucosa PPP6C 0.07 0.07 enet 21 0.08 7.1e-06 5.2 -5.4 6.8e-08 0.67 0.89 0.10 FALSE
12 GTEx Esophagus Mucosa PRPS1P2 0.07 0.08 lasso 3 0.07 1.5e-05 5.2 5.4 7.0e-08 -0.67 0.49 0.43 FALSE
13 GTEx Esophagus Muscularis OLFML2A 0.08 0.00 enet 27 0.00 4.9e-01 5.0 5.7 9.2e-09 -0.50 0.08 0.25 FALSE
14 GTEx Muscle Skeletal GAPVD1 0.13 0.10 lasso 3 0.09 4.7e-09 -6.3 6.3 2.4e-10 -0.95 0.02 0.98 FALSE
15 GTEx Nerve Tibial GAPVD1 0.17 0.08 lasso 10 0.10 9.3e-08 5.2 -6.3 3.1e-10 0.84 0.12 0.88 FALSE
16 GTEx Pancreas PRPS1P2 0.16 0.13 lasso 6 0.12 8.7e-06 5.2 5.3 1.2e-07 -0.67 0.81 0.16 FALSE
17 GTEx Skin Sun Exposed Lower leg GAPVD1 0.04 0.01 lasso 4 0.01 3.8e-02 5.2 -5.4 5.8e-08 0.77 0.21 0.68 FALSE
18 GTEx Thyroid NEK6 0.20 0.21 lasso 4 0.20 1.3e-15 5.2 -5.3 1.5e-07 0.05 0.31 0.69 FALSE
19 GTEx Thyroid GAPVD1 0.05 0.05 enet 13 0.01 6.6e-02 -6.2 -6.5 9.7e-11 0.96 0.02 0.98 FALSE
20 GTEx Thyroid PRPS1P2 0.08 0.09 enet 18 0.07 4.0e-06 5.2 5.2 1.6e-07 -0.72 0.86 0.13 FALSE
21 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma PPP6C 0.07 0.08 lasso 3 0.09 5.4e-10 5.2 -5.2 2.5e-07 0.68 0.03 0.97 FALSE
22 The Cancer Genome Atlas Brain Lower Grade Glioma PPP6C 0.02 0.02 lasso 2 0.01 1.5e-02 5.3 -5.2 1.9e-07 0.68 0.02 0.69 FALSE
23 The Cancer Genome Atlas Lung Adenocarcinoma PPP6C 0.02 0.02 lasso 4 0.02 7.6e-04 5.2 -5.2 2.0e-07 0.67 0.02 0.96 FALSE
24 The Cancer Genome Atlas Prostate Adenocarcinoma GAPVD1 0.02 0.04 enet 4 0.01 9.8e-03 -6.4 6.4 1.8e-10 -0.97 0.02 0.91 FALSE
25 The Cancer Genome Atlas Prostate Adenocarcinoma PPP6C 0.06 0.08 lasso 7 0.07 1.8e-07 5.2 -5.3 1.4e-07 0.64 0.02 0.98 FALSE
26 The Cancer Genome Atlas Prostate Adenocarcinoma PSMB7 0.03 0.04 lasso 4 0.04 1.2e-04 5.4 -5.3 9.5e-08 0.03 0.04 0.93 FALSE
27 The Cancer Genome Atlas Thyroid Carcinoma PPP6C 0.08 0.13 enet 9 0.13 5.5e-13 5.2 -5.2 2.1e-07 0.69 0.02 0.98 FALSE
28 The Cancer Genome Atlas Thyroid Carcinoma PSMB7 0.06 0.06 lasso 4 0.04 3.7e-05 5.5 -5.5 3.3e-08 0.07 0.08 0.92 FALSE