TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Arm fat-free mass (right)
:
←
→
chr17:36,211,659-37,644,854
Best TWAS P=7.88e-09 · Best GWAS P=2.31e-08 conditioned to 1
36.2M
36.4M
36.6M
36.8M
37M
37.2M
37.4M
37.6M
0
2
4
6
8
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
GTEx
Testis
PSMB3
0.30
0.24
lasso
4
0.21
8.9e-10
-5.6
-5.8
7.9e-09
1.00
0
1.00
TRUE
4
The Cancer Genome Atlas
Testicular Germ Cell Tumors
PSMB3
0.12
0.09
lasso
3
0.06
3.0e-03
-5.5
-5.6
1.8e-08
0.97
0
0.94
FALSE
5
The Cancer Genome Atlas
Thyroid Carcinoma
PSMB3
0.05
0.06
lasso
1
0.05
2.4e-05
-5.6
-5.6
2.3e-08
1.00
0
1.00
FALSE
3
NTR
Blood
PIP4K2B
0.02
0.01
lasso
3
0.01
6.4e-04
-5.6
5.5
2.8e-08
-0.97
0
0.99
FALSE
1
GTEx
Artery Tibial
PSMB3
0.10
0.02
enet
12
0.03
1.2e-03
-5.6
-5.4
5.7e-08
0.73
0
0.99
FALSE