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Traits
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Arm fat-free mass (right)
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chr2:35,884,899-37,567,226
Best TWAS P=1.08e-09 · Best GWAS P=4.04e-08 conditioned to 0.0502
35.8M
36M
36.2M
36.4M
36.6M
36.8M
37M
37.2M
37.4M
37.6M
0
2
4
6
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
4
GTEx
Spleen
FEZ2
0.42
0.16
enet
25
0.17
3.9e-05
4.6
6.1
1.1e-09
0.66
0.04
0.86
TRUE
2
GTEx
Adipose Subcutaneous
AC007401.1
0.10
0.02
lasso
4
0.02
5.4e-03
4.9
5.5
3.1e-08
0.87
0.02
0.94
FALSE
3
GTEx
Artery Tibial
CRIM1
0.10
0.04
lasso
4
0.05
1.4e-04
4.9
-5.4
6.6e-08
-0.86
0.02
0.97
FALSE
1
CommonMind
Brain Pre-frontal Cortex
FEZ2
0.16
0.24
lasso
2
0.22
1.3e-26
5.4
-5.4
6.7e-08
-0.97
0.00
1.00
FALSE
5
The Cancer Genome Atlas
Breast Invasive Carcinoma
FEZ2
0.01
0.01
blup
85
0.01
1.0e-03
4.5
-5.2
1.5e-07
-0.90
0.01
0.96
FALSE