[Hub]/) : Traits : Arm fat-free mass (right) :

chr20:19,318,837-21,919,054

Best TWAS P=1.57e-13 · Best GWAS P=8.56e-15 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex C20orf26 0.20 0.17 lasso 6 0.18 4.9e-21 -5.4 5.2 1.8e-07 -0.06 0.05 0.95 FALSE
2 CommonMind Brain Pre-frontal Cortex INSM1 0.07 0.00 bslmm 522 0.02 2.2e-03 4.2 5.8 5.6e-09 -0.01 0.08 0.15 TRUE
3 CommonMind Brain Pre-frontal Cortex PLK1S1 0.08 0.01 lasso 3 0.04 1.1e-05 6.0 5.8 5.9e-09 0.82 0.02 0.98 FALSE
4 GTEx Artery Tibial PLK1S1 0.07 0.08 enet 10 0.08 4.0e-07 7.6 7.4 1.6e-13 0.97 0.02 0.98 TRUE
5 GTEx Esophagus Mucosa PLK1S1 0.11 0.11 lasso 5 0.09 7.8e-07 5.9 5.9 3.9e-09 0.83 0.11 0.89 FALSE
6 GTEx Heart Atrial Appendage PLK1S1 0.15 -0.01 lasso 4 0.00 6.1e-01 1.2 5.4 5.4e-08 0.56 0.05 0.41 FALSE
7 GTEx Skin Not Sun Exposed Suprapubic PLK1S1 0.21 0.09 lasso 6 0.12 5.3e-07 7.3 6.3 3.8e-10 0.93 0.07 0.93 FALSE
8 GTEx Skin Sun Exposed Lower leg PLK1S1 0.15 0.13 enet 10 0.15 3.9e-12 6.0 5.4 7.6e-08 0.83 0.88 0.12 FALSE
9 GTEx Testis PLK1S1 0.64 0.34 enet 33 0.39 1.0e-18 6.0 6.4 1.9e-10 0.79 0.67 0.33 FALSE
10 GTEx Whole Blood PLK1S1 0.08 0.04 enet 9 0.02 4.0e-03 6.0 6.6 5.2e-11 0.89 0.06 0.94 FALSE
11 YFS Blood CRNKL1 0.21 0.25 enet 18 0.27 2.3e-89 -5.4 -5.2 2.4e-07 0.03 0.03 0.97 FALSE
12 The Cancer Genome Atlas Breast Invasive Carcinoma PLK1S1 0.05 0.07 enet 9 0.07 5.5e-15 5.8 6.4 1.7e-10 0.88 0.15 0.85 FALSE
13 The Cancer Genome Atlas Lung Adenocarcinoma PLK1S1 0.04 0.03 blup 64 0.04 4.0e-05 6.0 6.9 6.8e-12 0.88 0.11 0.88 FALSE
14 The Cancer Genome Atlas Pancreatic Adenocarcinoma PLK1S1 0.09 0.02 blup 64 0.05 3.1e-03 6.0 6.8 7.4e-12 0.78 0.03 0.54 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma PLK1S1 0.19 0.12 enet 14 0.13 4.3e-13 6.0 6.2 4.3e-10 0.80 0.86 0.14 FALSE
16 The Cancer Genome Atlas Thyroid Carcinoma PLK1S1 0.06 0.04 lasso 3 0.04 1.5e-04 6.0 6.1 1.0e-09 0.85 0.14 0.62 FALSE