[Hub]/) : Traits : Arm fat-free mass (right) :

chr3:9,283,299-11,999,795

Best TWAS P=1.07e-10 · Best GWAS P=3.98e-12 conditioned to 0.000172

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous CRELD1 0.46 0.16 enet 51 0.27 2.2e-22 -5.3 -5.4 5.5e-08 0.07 0.04 0.96 FALSE
2 GTEx Artery Aorta CRELD1 0.30 0.07 lasso 7 0.12 2.4e-07 -5.3 -5.3 1.2e-07 0.03 0.04 0.94 FALSE
3 GTEx Artery Aorta RP11-1020A11.1 0.15 0.01 lasso 3 0.00 4.0e-01 -5.3 -5.9 3.1e-09 -0.03 0.03 0.53 FALSE
4 GTEx Cells Transformed fibroblasts CRELD1 0.39 0.19 enet 39 0.28 4.5e-21 -5.3 -5.8 5.5e-09 0.04 0.04 0.96 FALSE
5 GTEx Cells Transformed fibroblasts HRH1 0.20 0.00 lasso 3 0.01 1.1e-01 6.9 -5.9 3.5e-09 -0.77 0.00 0.95 TRUE
6 GTEx Cells Transformed fibroblasts RP11-1020A11.1 0.20 0.10 enet 67 0.09 1.9e-07 -5.3 -5.2 1.6e-07 0.01 0.04 0.95 FALSE
7 GTEx Esophagus Muscularis CRELD1 0.21 0.10 lasso 1 0.08 1.7e-05 -5.3 -5.3 9.7e-08 -0.02 0.04 0.91 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic AC034193.5 0.15 0.09 enet 11 0.08 3.3e-05 4.9 5.3 9.5e-08 0.02 0.24 0.70 FALSE
9 GTEx Testis CRELD1 0.22 0.22 lasso 8 0.26 1.1e-11 4.9 -6.5 1.1e-10 0.00 0.12 0.88 TRUE
10 GTEx Thyroid BRK1 0.08 0.05 lasso 3 0.04 6.8e-04 4.9 -5.1 2.7e-07 0.01 0.21 0.78 FALSE
11 METSIM Adipose BRK1 0.04 0.02 bslmm 559 0.01 8.9e-03 4.6 -5.5 4.5e-08 -0.04 0.14 0.69 FALSE
12 ROSMAP Brain Pre-frontal Cortex AC022007.5 0.05 0.02 blup 515 0.03 2.8e-04 5.4 5.3 9.4e-08 0.02 0.04 0.96 FALSE
13 YFS Blood FANCD2 0.04 0.04 lasso 1 0.04 7.7e-13 5.4 -5.4 6.1e-08 -0.06 0.03 0.97 FALSE
14 The Cancer Genome Atlas Prostate Adenocarcinoma CIDECP 0.04 0.02 blup 33 0.03 3.8e-04 5.0 5.4 6.9e-08 0.00 0.04 0.90 FALSE
15 The Cancer Genome Atlas Prostate Adenocarcinoma LOC401052 0.06 0.07 enet 6 0.06 3.5e-07 5.5 -5.5 4.7e-08 -0.05 0.01 0.99 FALSE
16 The Cancer Genome Atlas Soft Tissue Sarcoma CRELD1 0.12 0.01 enet 22 0.04 1.4e-03 -2.0 -5.1 3.1e-07 0.04 0.02 0.19 FALSE