[Hub]/) : Traits : Arm fat-free mass (right) : ← →

chr4:305,291-2,437,290

Best TWAS P=3.23e-16 · Best GWAS P=1.78e-12 conditioned to 0.00166

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
50	NTR	Blood	CRIPAK	0.13	0.09	enet	31	0.15	1.5e-46	-4.75	-8.2	3.2e-16	0.00	1.00	0.00	TRUE
53	NTR	Blood	TACC3	0.05	0.03	lasso	9	0.04	2.7e-13	-5.53	6.8	9.7e-12	0.71	0.48	0.52	TRUE
12	GTEx	Brain Hippocampus	CRIPAK	0.48	0.22	lasso	4	0.23	4.0e-06	-5.35	-7.7	1.9e-14	0.00	0.11	0.48	FALSE
34	GTEx	Nerve Tibial	CRIPAK	0.50	0.11	enet	76	0.38	1.1e-28	-5.35	-7.6	4.3e-14	-0.08	1.00	0.00	FALSE
30	GTEx	Lung	CRIPAK	0.61	0.22	enet	46	0.41	1.1e-33	-4.88	-7.4	1.7e-13	0.02	1.00	0.00	FALSE
11	GTEx	Brain Cortex	CRIPAK	0.34	0.10	lasso	6	0.18	9.5e-06	-4.88	-7.2	5.4e-13	0.03	0.08	0.62	FALSE
47	METSIM	Adipose	CRIPAK	0.28	0.16	bslmm	335	0.25	2.7e-37	-4.99	-7.2	7.7e-13	-0.01	1.00	0.00	FALSE
18	GTEx	Breast Mammary Tissue (Female)	CRIPAK	0.32	0.17	enet	29	0.26	2.7e-08	-5.02	-7.1	1.1e-12	0.01	0.45	0.18	FALSE
38	GTEx	Pancreas	CRIPAK	0.34	0.13	lasso	6	0.27	1.0e-11	-5.35	-7.0	2.0e-12	0.01	0.77	0.08	FALSE
55	YFS	Blood	CRIPAK	0.35	0.27	bslmm	301	0.33	6.0e-112	-5.35	-7.0	2.0e-12	-0.03	0.99	0.01	FALSE
51	NTR	Blood	KIAA1530	0.19	0.04	blup	345	0.10	9.1e-32	-5.35	-6.9	4.5e-12	0.08	0.94	0.06	FALSE
36	GTEx	Ovary	CRIPAK	0.43	0.27	enet	19	0.32	9.0e-09	-4.88	-6.8	9.2e-12	0.03	0.34	0.31	FALSE
45	GTEx	Whole Blood	CRIPAK	0.38	0.17	lasso	9	0.28	3.4e-26	-5.35	-6.8	1.4e-11	0.02	0.99	0.01	FALSE
58	The Cancer Genome Atlas	Breast Invasive Carcinoma	CRIPAK	0.22	0.11	blup	28	0.14	5.6e-28	-5.35	-6.7	1.5e-11	0.01	0.00	1.00	FALSE
16	GTEx	Brain Putamen basal ganglia	CRIPAK	0.30	0.00	enet	25	0.10	1.9e-03	-4.89	-6.6	4.5e-11	0.11	0.03	0.45	FALSE
32	GTEx	Muscle Skeletal	FGFRL1	0.14	0.08	lasso	4	0.06	3.7e-06	-7.05	6.5	8.2e-11	0.01	0.00	1.00	FALSE
4	GTEx	Adipose Visceral Omentum	CRIPAK	0.47	0.24	lasso	12	0.31	1.3e-16	-4.88	-6.5	8.6e-11	0.02	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	CRIPAK	0.31	0.15	enet	34	0.26	1.2e-31	-5.05	-6.5	1.1e-10	0.04	1.00	0.00	FALSE
61	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CRIPAK	0.28	0.16	blup	28	0.19	3.2e-21	-5.35	-6.5	1.1e-10	0.03	0.00	1.00	FALSE
52	NTR	Blood	SLBP	0.04	0.02	lasso	5	0.02	2.8e-08	-5.64	6.4	1.5e-10	0.82	0.04	0.96	FALSE
73	The Cancer Genome Atlas	Thyroid Carcinoma	CRIPAK	0.38	0.22	enet	12	0.25	5.4e-24	-5.35	-6.4	2.0e-10	0.01	0.00	1.00	FALSE
33	GTEx	Muscle Skeletal	CRIPAK	0.25	0.11	enet	32	0.18	7.6e-18	-4.88	-6.3	2.3e-10	0.03	0.97	0.03	FALSE
15	GTEx	Brain Nucleus accumbens basal ganglia	CRIPAK	0.34	0.13	lasso	6	0.25	2.7e-07	-4.88	-6.3	2.4e-10	0.05	0.17	0.22	FALSE
9	GTEx	Brain Cerebellum	CRIPAK	0.37	0.09	enet	24	0.31	8.8e-10	-5.07	-6.3	2.7e-10	-0.01	0.22	0.47	FALSE
13	GTEx	Brain Hypothalamus	CRIPAK	0.22	0.00	lasso	5	0.01	2.1e-01	-5.35	-6.3	3.0e-10	0.02	0.06	0.08	FALSE
19	GTEx	Cells EBV-transformed lymphocytes	CRIPAK	0.49	0.27	lasso	8	0.35	2.9e-12	-4.88	-6.3	4.0e-10	0.05	0.84	0.01	FALSE
26	GTEx	Esophagus Mucosa	CRIPAK	0.49	0.14	enet	28	0.40	6.8e-29	-4.88	-6.2	4.6e-10	0.00	0.77	0.23	FALSE
31	GTEx	Lung	RP11-20I20.4	0.07	0.00	lasso	3	0.01	6.0e-02	-5.17	-6.2	5.6e-10	0.03	0.14	0.03	FALSE
63	The Cancer Genome Atlas	Brain Lower Grade Glioma	CRIPAK	0.31	0.11	enet	10	0.18	1.5e-19	-5.35	-6.2	5.7e-10	-0.03	0.00	1.00	FALSE
25	GTEx	Esophagus Gastroesophageal Junction	CRIPAK	0.33	0.20	lasso	5	0.30	1.4e-11	-4.88	-6.1	7.9e-10	0.02	0.98	0.00	FALSE
2	GTEx	Adipose Subcutaneous	CRIPAK	0.42	0.11	enet	42	0.34	9.0e-29	-5.04	-6.1	8.6e-10	0.04	1.00	0.00	FALSE
29	GTEx	Heart Atrial Appendage	CRIPAK	0.31	0.26	enet	23	0.33	2.1e-15	-4.88	-6.1	1.2e-09	0.03	1.00	0.00	FALSE
54	ROSMAP	Brain Pre-frontal Cortex	CRIPAK	0.31	0.23	lasso	12	0.40	6.4e-55	-4.99	-6.1	1.2e-09	0.01	1.00	0.00	FALSE
62	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	CRIPAK	0.21	0.10	enet	9	0.15	1.3e-16	-5.35	-6.1	1.2e-09	0.00	0.00	1.00	FALSE
70	The Cancer Genome Atlas	Rectum Adenocarcinoma	CRIPAK	0.37	0.07	lasso	2	0.12	1.2e-03	-5.35	-6.1	1.2e-09	0.03	0.00	0.82	FALSE
22	GTEx	Colon Transverse	CRIPAK	0.33	0.10	enet	22	0.24	5.8e-12	-5.35	-6.1	1.4e-09	0.03	0.95	0.02	FALSE
60	The Cancer Genome Atlas	Colon Adenocarcinoma	CRIPAK	0.38	0.16	blup	28	0.21	2.8e-12	-5.35	-6.0	1.7e-09	0.01	0.00	1.00	FALSE
49	METSIM	Adipose	UVSSA	0.26	0.04	bslmm	366	0.12	9.0e-18	1.56	-6.0	1.9e-09	0.02	0.63	0.37	FALSE
8	GTEx	Brain Caudate basal ganglia	CRIPAK	0.27	0.00	lasso	2	0.02	9.3e-02	-5.35	-6.0	2.3e-09	0.01	0.06	0.12	FALSE
28	GTEx	Esophagus Muscularis	CRIPAK	0.38	0.14	enet	34	0.30	2.6e-18	-4.88	-5.9	3.1e-09	0.05	1.00	0.00	FALSE
64	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	CRIPAK	0.13	0.06	blup	29	0.08	1.2e-04	-5.35	-5.9	3.2e-09	0.01	0.00	0.98	FALSE
6	GTEx	Artery Aorta	CRIPAK	0.31	0.20	enet	34	0.30	2.8e-17	-4.88	-5.9	3.6e-09	0.01	0.96	0.04	FALSE
21	GTEx	Colon Transverse	TMEM129	0.23	0.05	lasso	4	0.03	1.8e-02	-5.54	5.8	5.1e-09	0.51	0.09	0.09	FALSE
17	GTEx	Breast Mammary Tissue	CRIPAK	0.42	0.12	enet	35	0.39	5.2e-21	-4.88	-5.8	5.2e-09	0.02	0.99	0.00	FALSE
20	GTEx	Colon Sigmoid	CRIPAK	0.40	0.21	lasso	7	0.30	4.7e-11	-5.17	-5.8	5.7e-09	0.06	0.70	0.04	FALSE
68	The Cancer Genome Atlas	Pheochromocytoma and Paraganglioma	CRIPAK	0.41	0.10	lasso	4	0.08	5.2e-04	-5.35	-5.8	5.8e-09	0.02	0.00	0.98	FALSE
35	GTEx	Ovary	UVSSA	0.33	0.10	enet	12	0.32	1.5e-08	-5.35	-5.8	6.0e-09	0.02	0.08	0.30	FALSE
43	GTEx	Uterus	CRIPAK	0.52	0.34	lasso	3	0.33	1.7e-07	-5.35	-5.8	7.1e-09	0.01	0.23	0.07	FALSE
5	GTEx	Artery Aorta	UVSSA	0.33	0.06	enet	30	0.28	7.2e-16	-5.35	-5.8	7.3e-09	0.01	0.02	0.98	FALSE
66	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	CRIPAK	0.14	0.05	lasso	4	0.07	6.1e-08	-5.35	-5.7	9.0e-09	0.01	0.00	1.00	FALSE
3	GTEx	Adipose Visceral Omentum	UVSSA	0.46	0.05	lasso	11	0.24	1.1e-12	-5.35	-5.7	9.4e-09	0.01	0.39	0.56	FALSE
57	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	CRIPAK	0.11	0.07	lasso	4	0.05	2.0e-05	-5.35	-5.7	9.7e-09	0.00	0.00	1.00	FALSE
71	The Cancer Genome Atlas	Soft Tissue Sarcoma	CRIPAK	0.20	0.10	lasso	5	0.15	2.2e-09	-4.88	-5.7	1.0e-08	0.07	0.02	0.98	FALSE
23	GTEx	Colon Transverse	RP11-20I20.4	0.17	0.05	lasso	3	0.05	2.3e-03	-5.17	-5.7	1.2e-08	0.01	0.42	0.03	FALSE
69	The Cancer Genome Atlas	Prostate Adenocarcinoma	CRIPAK	0.27	0.17	enet	4	0.18	2.7e-18	-5.35	-5.7	1.5e-08	0.00	0.00	1.00	FALSE
56	YFS	Blood	SLBP	0.10	0.12	lasso	3	0.12	1.2e-35	-5.53	5.5	3.4e-08	0.60	0.96	0.04	FALSE
14	GTEx	Brain Nucleus accumbens basal ganglia	UVSSA	0.24	0.00	enet	33	0.04	2.8e-02	0.98	-5.5	3.8e-08	-0.10	0.06	0.16	FALSE
40	GTEx	Skin Sun Exposed Lower leg	CRIPAK	0.36	0.09	enet	40	0.35	8.7e-30	-5.04	-5.5	4.5e-08	0.03	0.99	0.01	FALSE
24	GTEx	Esophagus Gastroesophageal Junction	UVSSA	0.30	0.00	enet	23	0.08	1.1e-03	-4.88	-5.5	4.6e-08	0.09	0.27	0.08	FALSE
46	GTEx	Whole Blood	AC016773.1	0.27	0.21	enet	8	0.22	1.2e-19	-5.54	5.4	5.3e-08	0.53	0.96	0.04	FALSE
44	GTEx	Whole Blood	TACC3	0.11	0.05	enet	7	0.06	2.8e-06	-3.53	5.4	5.4e-08	0.59	0.93	0.04	FALSE
39	GTEx	Skin Not Sun Exposed Suprapubic	CRIPAK	0.39	0.14	lasso	13	0.34	1.5e-19	-4.88	-5.4	5.7e-08	0.01	0.33	0.67	FALSE
59	The Cancer Genome Atlas	Breast Invasive Carcinoma	KIAA1530	0.13	0.01	blup	48	0.03	4.9e-07	-5.07	-5.4	6.0e-08	-0.05	0.00	0.99	FALSE
67	The Cancer Genome Atlas	Pancreatic Adenocarcinoma	CRIPAK	0.34	0.30	lasso	3	0.27	7.5e-12	-5.35	-5.4	8.6e-08	0.00	0.00	1.00	FALSE
65	The Cancer Genome Atlas	Lung Adenocarcinoma	CRIPAK	0.09	0.07	lasso	1	0.06	1.5e-07	-5.35	-5.4	8.7e-08	-0.01	0.00	1.00	FALSE
74	The Cancer Genome Atlas	Thyroid Carcinoma	FAM53A	0.05	0.03	blup	56	0.04	1.8e-04	3.85	5.3	1.4e-07	0.79	0.01	0.95	FALSE
72	The Cancer Genome Atlas	Stomach Adenocarcinoma	CRIPAK	0.17	0.07	blup	29	0.08	1.3e-06	-3.81	-5.2	1.5e-07	0.08	0.03	0.95	FALSE
41	GTEx	Stomach	CRIPAK	0.43	0.22	enet	46	0.35	1.4e-17	-4.88	-5.2	1.7e-07	0.06	0.98	0.01	FALSE
37	GTEx	Pancreas	TMEM129	0.20	0.19	lasso	3	0.14	1.5e-06	-5.54	5.2	1.8e-07	0.58	0.86	0.06	FALSE
27	GTEx	Esophagus Muscularis	UVSSA	0.35	0.03	enet	33	0.16	3.5e-10	-4.88	-5.2	1.9e-07	0.03	0.82	0.12	FALSE
42	GTEx	Thyroid	AC016773.1	0.11	0.07	enet	7	0.06	3.9e-05	-5.64	5.2	1.9e-07	0.52	0.66	0.06	FALSE
7	GTEx	Artery Tibial	CRIPAK	0.42	0.09	enet	50	0.34	1.3e-27	1.89	-5.2	2.5e-07	0.02	1.00	0.00	FALSE
10	GTEx	Brain Cortex	RNF212	0.15	0.03	lasso	3	0.01	1.5e-01	-4.92	5.2	2.5e-07	-0.01	0.10	0.08	FALSE
48	METSIM	Adipose	TMEM129	0.11	0.09	lasso	8	0.09	3.3e-13	-5.53	5.2	2.6e-07	0.57	0.96	0.04	FALSE