TWAS hub - TPBG

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0870	0.0340	2.8e-04	0.010	0.037	0.015	0.040	0.016	1.7e-02	2.2e-05	4.6e-03	1.2e-05	3.8e-03
2	GTEx	Adipose Subcutaneous	0.2320	0.0560	2.8e-10	0.202	NA	0.184	NA	0.191	2.2e-16	NA	6.4e-15	NA	1.6e-15
3	GTEx	Artery Aorta	0.2310	0.0610	5.4e-09	0.227	NA	0.227	NA	0.240	1.0e-12	NA	1.1e-12	NA	2.0e-13
4	GTEx	Artery Coronary	0.1780	0.0690	1.9e-03	0.152	NA	0.132	NA	0.154	8.0e-06	NA	3.5e-05	NA	7.4e-06
5	GTEx	Artery Tibial	0.2130	0.0475	4.7e-12	0.237	NA	0.195	NA	0.218	1.5e-18	NA	3.1e-15	NA	5.4e-17
6	GTEx	Muscle Skeletal	0.0441	0.0201	4.6e-03	0.049	NA	0.028	NA	0.037	1.4e-05	NA	9.1e-04	NA	1.5e-04
7	GTEx	Nerve Tibial	0.1847	0.0522	1.6e-06	0.158	NA	0.167	NA	0.168	2.6e-11	NA	6.8e-12	NA	6.1e-12
8	GTEx	Skin Not Sun Exposed Suprapubic	0.1170	0.0450	6.0e-04	0.138	NA	0.099	NA	0.121	5.1e-08	NA	4.6e-06	NA	3.6e-07
9	GTEx	Skin Sun Exposed Lower leg	0.1470	0.0410	4.6e-08	0.124	NA	0.129	NA	0.134	2.1e-10	NA	7.7e-11	NA	3.1e-11
10	GTEx	Testis	0.1090	0.0450	3.9e-03	0.037	NA	0.093	NA	0.088	9.1e-03	NA	6.4e-05	NA	9.9e-05
11	METSIM	Adipose	0.0472	0.0233	3.9e-03	0.060	0.017	0.053	0.053	0.057	2.6e-09	1.0e-03	2.1e-08	1.8e-08	5.7e-09
12	NTR	Blood	0.0254	0.0128	3.5e-03	0.002	0.007	0.017	0.014	0.005	5.9e-02	1.7e-03	3.2e-06	1.9e-05	9.1e-03
13	ROSMAP	Brain Pre-frontal Cortex	0.0398	0.0164	1.1e-03	0.047	0.019	0.014	0.015	0.027	1.0e-06	1.3e-03	5.7e-03	3.9e-03	1.7e-04

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	13
Happiness	5.3	6.5	8.8	2.5	2.9	2.7	2.5	2.8	2.9	2.8	3.0	2.8	-2.1	2.8	1.6
Supplements: Fish oil (including cod liver oil)	5.3	6.9	8.8	2.4	2.8	2.9	2.7	3.0	2.7	2.7	2.9	2.8	-2.7	2.9	2.3
Supplements: Calcium	5.3	5.9	7.5	2.3	2.7	2.6	2.6	2.6	2.7	2.7	2.6	2.7	-2.5	2.6	1.3
Family relationship satisfaction	5.0	6.1	13.9	2.1	2.6	2.5	2.5	2.4	2.6	2.3	2.5	2.5	-3.7	2.5	2.2
Had other major operations	4.9	6.0	8.0	2.4	2.8	2.7	2.3	2.7	2.8	2.8	2.7	2.8	-2.2	2.8	0.9
Gout (self-reported)	4.8	6.6	9.5	-2.4	-3.1	-2.8	-2.6	-2.8	-3.0	-2.6	-3.0	-3.0	2.4	-2.9	-0.2
Emphysema/chronic bronchitis	4.7	5.3	7.5	2.0	2.5	2.6	2.7	2.7	2.4	2.6	2.6	2.5	-1.6	2.5	1.4
Financial situation satisfaction	4.1	5.1	8.8	0.8	2.7	2.5	2.3	2.6	2.7	3.0	2.7	2.6	-1.7	2.7	0.5
Pain experienced in last month	3.8	6.4	8.9	-1.9	-2.8	-2.9	-2.4	-3.0	-2.6	-2.5	-3.0	-2.8	2.2	-3.0	-2.2
Smoking status: Previous	3.7	5.5	9.2	1.4	2.6	2.8	3.0	2.6	2.7	2.5	2.4	2.7	-2.1	2.5	0.9
Friendships satisfaction	3.7	4.6	6.6	2.6	2.3	2.3	2.4	2.3	2.3	2.3	2.3	2.3	-2.0	2.3	0.8
Depressed Affect (Nagel 2018)	3.6	7.7	11.5	-1.2	-3.2	-3.1	-2.9	-3.2	-3.4	-3.1	-3.1	-3.4	2.9	-3.0	-1.1
Townsend deprivation index at recruitment	3.3	4.7	7.4	0.6	2.5	2.4	2.1	2.5	2.5	2.7	2.6	2.5	-1.3	2.5	1.8
Multivitamins +/- minerals	3.0	3.9	9.1	2.3	1.9	1.8	2.0	1.8	1.9	1.4	1.8	1.8	-2.7	1.8	3.0
Medication: Allopurinol	3.0	4.0	5.3	-2.3	-2.3	-2.1	-2.0	-2.1	-2.3	-1.7	-2.2	-2.2	1.5	-2.2	-1.8
Handedness (chirality/laterality): Left-handed	2.9	3.4	5.3	1.3	2.1	2.1	2.3	2.1	2.0	1.9	2.0	2.2	-1.6	1.9	1.3
Schizophrenia (2018)	2.8	5.9	8.4	1.4	2.8	2.9	2.6	2.7	2.8	2.9	2.9	2.8	-1.1	2.7	1.9
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.8	3.3	4.8	-1.6	-1.9	-2.0	-1.9	-2.1	-1.9	-2.0	-1.9	-2.1	1.2	-1.9	-2.2
Overall health rating	2.7	5.7	13.9	3.7	2.4	2.4	2.6	2.5	2.2	2.1	2.4	2.3	-1.3	2.5	2.9
Other serious medical condition/disability diagnosed by doctor	2.6	3.4	5.3	2.2	2.0	2.0	1.9	1.9	2.0	1.6	1.9	1.9	-1.2	2.0	2.3
Pulse rate	2.4	4.1	7.8	-2.3	-2.1	-2.3	-2.8	-2.1	-2.0	-1.8	-2.1	-2.1	1.8	-2.0	-1.7
Neck or shoulder pain in last month	2.4	3.4	6.2	1.4	1.8	2.0	2.2	1.9	1.8	1.8	1.9	1.8	-2.1	1.8	2.5
Medication: Ibuprofen	2.4	2.9	4.2	-1.1	-2.0	-2.0	-1.9	-2.0	-2.0	-1.9	-2.1	-2.0	0.7	-2.0	-0.6
Breast cancer (self-reported)	2.4	2.8	5.5	0.7	1.9	1.9	2.4	1.8	1.9	1.5	1.8	1.8	-2.1	1.8	0.7
Bipolar Disorder or Schizophrenia	2.3	5.6	8.0	2.3	2.5	2.7	2.8	2.6	2.6	2.5	2.6	2.7	-0.4	2.5	2.4
Coronary Artery Disease (CAD)	2.3	2.7	6.0	0.6	1.7	2.1	2.4	1.9	1.6	1.7	1.7	1.7	-1.9	1.7	-0.6
Medication: Ibuprofen (e.g. Nurofen)	2.3	2.9	4.6	-1.2	-2.0	-1.9	-1.7	-2.0	-2.0	-2.0	-2.1	-2.0	0.2	-2.0	-0.6
Miserableness	2.3	3.9	7.2	-0.7	-2.2	-2.2	-2.3	-2.1	-2.4	-2.0	-2.0	-2.3	2.7	-2.0	-1.2
Hearing aid user	2.3	2.6	4.0	-1.0	-1.8	-1.7	-1.6	-1.9	-1.7	-2.0	-1.9	-1.8	0.6	-1.9	-1.6
Osteoporosis (self-reported)	2.2	2.7	4.2	1.5	1.8	1.9	2.0	1.9	1.7	1.4	1.8	1.8	-1.9	1.8	-0.1
Commuting to job workplace: Public transport	2.2	2.7	4.1	0.3	1.8	1.9	2.0	1.7	1.8	1.9	1.8	1.8	-1.2	1.7	1.7
Age when periods started (menarche)	2.1	5.0	7.1	2.3	2.5	2.5	2.4	2.5	2.7	2.4	2.4	2.6	-1.5	2.5	1.3
Eye problems/disorders: None of the above	2.1	2.4	3.6	-1.2	-1.8	-1.9	-1.8	-1.8	-1.7	-1.8	-1.8	-1.7	0.5	-1.9	-1.1
Suffer from ‘nerves’	2.0	3.1	4.1	2.0	1.9	1.8	1.8	1.9	1.9	1.6	1.9	1.9	-1.6	1.8	1.9
Illnesses of siblings	1.9	2.7	3.8	-1.9	-1.8	-1.8	-1.5	-1.9	-1.9	-1.6	-1.9	-1.9	1.3	-1.9	-0.3
Prospective memory result	1.9	2.4	4.1	-0.7	-1.9	-1.6	-1.2	-1.9	-1.9	-2.0	-1.8	-1.9	0.7	-1.9	-0.9
Serious illness, injury or assault to yourself	1.8	2.2	5.9	2.4	1.3	1.4	1.3	1.3	1.3	1.1	1.2	1.3	-1.5	1.3	2.2
Past tobacco smoking	1.8	3.2	6.2	-0.9	-1.9	-2.2	-2.5	-2.0	-2.0	-1.9	-1.9	-2.0	1.3	-2.0	-1.0
Reason for reducing amount of alcohol drunk: Health precaution	1.8	2.1	4.8	-1.1	-1.5	-1.9	-2.2	-1.6	-1.4	-1.9	-1.6	-1.4	0.6	-1.6	0.3
Mood swings	1.8	3.2	5.1	-0.9	-1.9	-2.0	-2.2	-1.9	-2.0	-1.9	-1.9	-2.0	1.6	-1.9	-1.7
Medication: Omeprazole (e.g. Zanprol)	1.8	2.1	3.3	0.1	-1.8	-1.6	-1.2	-1.6	-1.8	-1.7	-1.8	-1.7	0.7	-1.8	-1.3
Neuroticism (Nagel 2018)	1.7	4.1	6.8	0.2	-2.5	-2.3	-2.2	-2.3	-2.6	-2.5	-2.4	-2.5	0.6	-2.4	0.4
Systolic Blood Pressure	1.7	8.6	21.8	-4.7	-3.0	-3.2	-3.8	-3.0	-3.1	-2.3	-2.8	-3.1	1.8	-2.9	-2.0
Worrier / anxious feelings	1.7	3.1	4.8	0.2	-2.1	-2.1	-2.1	-2.1	-2.1	-2.2	-2.0	-2.1	0.4	-2.1	0.5
Number of live births	1.7	2.4	5.6	-0.3	-1.8	-1.7	-1.4	-1.6	-1.7	-1.9	-1.6	-1.8	2.4	-1.6	-0.3
Hand grip strength (right)	1.6	4.4	6.5	-2.6	-2.3	-2.2	-2.0	-2.1	-2.3	-2.2	-2.4	-2.2	1.4	-2.3	-2.2
Medication for pain relief, constipation, heartburn	1.6	2.7	4.4	0.4	2.0	2.0	1.6	1.9	2.1	2.0	2.1	2.0	-0.1	1.9	0.2
Long-standing illness, disability or infirmity	1.6	2.5	7.1	2.3	1.5	1.4	1.1	1.5	1.4	1.5	1.5	1.4	-1.2	1.6	2.7
Wears glasses or contact lenses	1.6	1.8	3.5	-1.1	-1.4	-1.4	-1.5	-1.4	-1.4	-1.3	-1.4	-1.5	0.7	-1.3	-1.9
Alzheimer’s Disease (including proxy)	1.5	2.2	3.2	0.0	-1.8	-1.5	-1.1	-1.7	-1.8	-1.8	-1.8	-1.6	1.8	-1.8	0.5
Schizophrenia (2014)	1.5	3.3	4.7	1.5	2.0	2.1	1.8	2.0	2.1	2.2	2.1	2.1	-0.2	2.0	1.8
Pain all over the body in last month	1.5	1.6	10.4	2.0	0.8	0.9	0.8	1.0	0.8	0.7	0.9	1.0	-0.4	0.9	3.2
Impedance of arm (right)	1.5	7.2	19.8	2.7	2.7	2.5	2.7	2.6	2.6	2.8	2.8	2.7	-4.5	2.5	1.8
Arm fat-free mass (right)	1.5	7.6	31.0	-1.6	-2.7	-2.5	-2.6	-2.6	-2.6	-2.9	-2.9	-2.6	5.6	-2.6	-0.3
Arm predicted mass (right)	1.5	7.5	30.9	-1.6	-2.6	-2.5	-2.7	-2.6	-2.6	-2.8	-2.9	-2.6	5.6	-2.6	0.2
Age at last live birth	1.5	2.1	3.0	-0.8	-1.6	-1.6	-1.7	-1.7	-1.6	-1.4	-1.5	-1.7	1.4	-1.6	1.1
Smoking status: Current	1.5	2.3	4.1	-1.1	-1.8	-1.6	-1.3	-1.7	-1.9	-1.6	-1.6	-2.0	1.7	-1.6	0.7
Type 2 Diabetes (T2D) (2012)	1.4	1.6	2.3	-0.7	-1.4	-1.4	-0.9	-1.5	-1.4	-1.4	-1.5	-1.5	1.5	-1.4	-1.1
Current tobacco smoking	1.4	2.3	4.1	-1.0	-1.8	-1.6	-1.4	-1.7	-1.9	-1.6	-1.6	-2.0	1.6	-1.6	0.5
Health satisfaction	1.4	1.8	4.8	2.2	1.3	1.3	1.3	1.4	1.2	1.2	1.4	1.3	-1.4	1.3	1.3
Average weekly red wine intake	1.4	2.1	3.3	1.5	1.8	1.4	1.0	1.6	1.8	1.6	1.6	1.8	-1.3	1.6	0.8
Medication: Gliclazide	1.4	1.6	2.4	-1.0	-1.2	-1.3	-1.4	-1.2	-1.2	-1.4	-1.3	-1.3	1.5	-1.2	-1.6
Neuroticism (2016)	1.3	1.9	4.2	-0.2	-1.6	-1.7	-2.1	-1.6	-1.6	-1.5	-1.6	-1.6	0.7	-1.6	-0.0
Neuroticism	1.3	3.2	5.6	0.1	-2.2	-2.1	-2.1	-2.1	-2.4	-2.0	-2.0	-2.2	0.9	-2.0	0.1
Taking other prescription medications	1.3	2.0	3.7	1.5	1.4	1.5	1.4	1.5	1.4	1.4	1.5	1.4	-1.9	1.6	0.7
Mouth/teeth dental problems	1.3	2.0	6.7	0.9	1.5	1.4	1.6	1.5	1.4	1.1	1.3	1.5	-0.5	1.3	2.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.3	1.7	5.1	1.1	1.3	1.2	1.1	1.4	1.3	1.2	1.4	1.4	-0.9	1.3	2.3
Mineral and other dietary supplements	1.3	1.7	3.5	-1.3	-1.3	-1.3	-1.1	-1.4	-1.2	-1.2	-1.3	-1.3	1.9	-1.4	-1.5
Systolic blood pressure, automated reading	1.2	3.6	7.4	-2.1	-1.9	-2.1	-2.7	-1.9	-1.9	-1.6	-1.8	-2.0	1.8	-1.8	-1.6
Vitamin and mineral supplements	1.2	1.6	3.3	-1.5	-1.2	-1.2	-1.2	-1.2	-1.1	-0.9	-1.2	-1.2	1.8	-1.2	-1.7
Angina (self-reported)	1.2	1.5	3.4	-1.5	-1.2	-1.2	-1.5	-1.1	-1.2	-1.1	-1.1	-1.3	1.8	-1.1	-1.0
Medication: Bendroflumethiazide	1.2	1.9	5.2	-0.5	-1.2	-1.4	-1.7	-1.3	-1.1	-1.8	-1.2	-1.2	1.3	-1.2	-2.3
Alcohol drinker status: Previous	1.2	1.4	4.8	0.9	1.1	1.1	1.3	1.1	1.1	0.9	1.0	1.1	-1.4	1.0	2.2
Breast Cancer	1.1	2.6	5.8	-1.4	-1.6	-1.7	-1.5	-1.7	-1.7	-1.8	-1.9	-1.5	0.9	-1.8	-2.4
HbA1C	1.1	1.2	4.3	2.1	1.0	0.9	1.0	0.9	0.9	0.6	1.0	1.0	-1.4	0.9	1.2
Supplements: Zinc	1.1	1.2	4.5	1.4	1.1	1.0	1.1	1.0	1.0	0.9	0.9	1.0	-0.9	1.0	2.1
Ever taken oral contraceptive pill	1.1	1.3	3.6	1.0	1.1	1.1	1.6	1.0	1.0	0.9	0.9	1.0	-1.0	1.0	1.9
Arm fat-free mass (left)	1.1	5.7	29.2	-1.4	-2.1	-2.0	-2.3	-2.0	-2.1	-2.4	-2.3	-2.1	5.4	-2.1	0.1
Age at First Birth	1.0	1.4	2.4	-0.3	-1.2	-1.5	-1.6	-1.5	-1.1	-1.4	-1.5	-1.3	0.9	-1.3	0.4
Medication: Simvastatin	1.0	1.4	2.2	-0.7	-1.4	-1.4	-1.5	-1.3	-1.4	-1.1	-1.2	-1.4	1.0	-1.2	-1.1
Hip circumference	1.0	4.1	20.2	-1.5	-1.9	-1.7	-1.6	-1.7	-1.9	-2.2	-1.9	-1.8	4.5	-1.8	-0.9
Impedance of arm (left)	1.0	4.7	16.5	2.5	2.0	1.9	2.3	1.9	1.9	2.1	2.1	2.1	-4.1	1.8	1.3
Medication: Omeprazole	1.0	1.2	2.1	0.5	-1.4	-1.2	-0.7	-1.2	-1.4	-1.3	-1.4	-1.3	0.3	-1.4	-0.2
Unable to work because of sickness or disability	1.0	1.3	3.2	1.8	1.2	1.2	0.9	1.3	1.0	1.0	1.2	1.1	-0.2	1.3	1.5
Arm predicted mass (left)	1.0	5.3	29.1	-1.2	-2.0	-1.9	-2.2	-1.9	-2.0	-2.3	-2.2	-2.0	5.4	-1.9	0.3
Bipolar Disorder (2011)	0.9	0.8	1.6	-0.2	1.0	1.0	1.2	1.0	1.0	1.2	1.0	1.0	0.3	0.9	1.1
Hand grip strength (left)	0.9	2.4	7.3	-2.7	-1.6	-1.5	-1.5	-1.5	-1.6	-1.5	-1.7	-1.5	1.1	-1.6	-1.2
Eye problems/disorders: Diabetes related eye disease	0.9	0.9	1.4	-0.8	1.1	1.2	0.9	1.2	1.1	1.2	1.0	1.1	0.1	1.1	-0.7
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	4.0	1.0	1.2	1.0	0.8	1.0	1.1	1.2	1.1	1.0	-0.5	1.1	2.0
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.2	1.5	1.0	1.0	0.9	1.1	1.0	0.9	1.2	1.0	-1.0	1.0	1.2
Sitting height	0.9	6.5	11.7	-2.0	-2.6	-2.7	-2.7	-2.8	-2.5	-2.7	-3.0	-2.6	3.4	-2.8	1.4
Number of incorrect matches in round	0.9	1.4	2.9	-0.7	-1.5	-1.3	-0.6	-1.6	-1.4	-1.4	-1.7	-1.5	-0.4	-1.6	-0.2
Nervous feelings	0.9	1.6	7.7	2.4	0.7	0.4	0.2	0.6	0.7	0.6	0.7	0.8	-2.1	0.6	2.8
Heel bone mineral density (BMD) T-score, automated (right)	0.9	2.0	4.5	-0.1	1.7	1.5	1.1	1.4	1.6	1.9	1.5	1.6	-2.1	1.4	-0.1
Medication: Cholesterol lowering	0.9	1.3	2.5	0.0	-1.3	-1.4	-1.6	-1.2	-1.3	-1.4	-1.3	-1.3	0.7	-1.2	-0.8
Tense / ‘highly strung’	0.9	1.5	3.6	0.3	-1.4	-1.4	-1.0	-1.5	-1.4	-1.1	-1.3	-1.4	0.2	-1.4	1.9
Hair/balding pattern: Pattern 4	0.9	2.2	5.8	-1.5	-1.4	-1.3	-1.4	-1.5	-1.4	-1.1	-1.3	-1.5	2.4	-1.4	-1.7
High blood pressure (siblings)	0.9	1.2	4.8	2.2	1.1	1.1	0.9	1.1	1.1	0.9	1.2	1.1	-0.8	1.1	0.7
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.7	-1.6	-1.0	-1.0	-1.0	-0.9	-1.0	-0.8	-1.0	-0.9	1.2	-0.9	-1.2
Pulse rate, automated reading	0.9	2.8	6.0	-2.5	-1.7	-1.8	-2.4	-1.5	-1.8	-1.3	-1.6	-1.7	1.4	-1.5	-0.9
Illness, injury, bereavement, stress in last 2 years	0.9	1.1	9.3	0.3	-0.8	-0.6	-0.2	-0.7	-0.7	-0.8	-0.8	-0.8	-0.1	-0.8	-3.0
Osteoarthritis (self-reported)	0.9	1.1	3.9	1.2	0.8	0.9	0.8	0.9	0.8	0.9	0.7	0.9	-2.0	0.8	1.7
Ever had prostate specific antigen (PSA) test	0.9	1.1	5.8	-0.6	-1.0	-0.9	-0.7	-1.0	-1.0	-0.7	-0.8	-1.1	0.4	-0.9	-2.4
Blood White Count	0.8	6.1	9.6	-3.1	-2.6	-2.5	-2.2	-2.7	-2.7	-2.5	-2.7	-2.7	2.4	-2.6	-2.1
Sensitivity / hurt feelings	0.8	1.3	2.0	1.1	-1.3	-1.3	-1.4	-1.2	-1.4	-1.4	-1.2	-1.4	0.4	-1.2	-0.4
Relative age of first facial hair	0.8	1.6	2.6	-0.0	-1.5	-1.5	-1.3	-1.4	-1.6	-1.6	-1.6	-1.4	0.8	-1.5	0.5
Ever had hysterectomy (womb removed)	0.8	0.9	1.6	0.1	1.0	0.9	1.0	1.0	1.0	1.1	1.0	1.0	-1.0	1.0	1.3
Angina	0.8	1.1	2.8	-1.3	-1.0	-0.9	-1.3	-0.9	-1.0	-0.9	-0.8	-1.0	1.7	-0.8	-0.8
Average weekly fortified wine intake	0.8	1.0	2.5	-0.5	-1.1	-1.2	-1.6	-1.0	-1.0	-1.2	-1.0	-1.0	0.6	-1.0	-0.8
Relative age voice broke	0.8	1.3	2.5	0.7	-1.3	-1.3	-1.4	-1.2	-1.4	-1.6	-1.3	-1.3	0.0	-1.2	0.5
Medication: Atenolol	0.8	1.0	3.4	-1.8	-0.7	-0.8	-1.1	-0.7	-0.8	-0.7	-0.7	-0.8	1.6	-0.6	-1.1
Trunk fat-free mass	0.8	4.3	21.6	-1.0	-1.9	-1.8	-1.9	-1.9	-1.8	-2.1	-2.1	-1.8	4.7	-1.9	0.4
Time employed in main current job	0.8	0.9	2.1	-0.5	-1.0	-0.9	-0.8	-1.0	-1.0	-1.0	-0.7	-1.1	1.1	-0.9	-1.4
Mouth/teeth dental problems: Dentures	0.8	1.4	4.4	-1.1	-1.2	-1.2	-1.4	-1.2	-1.2	-1.0	-1.0	-1.3	0.5	-1.0	-2.1
Trunk predicted mass	0.8	4.6	22.5	-1.1	-2.0	-1.9	-2.0	-2.0	-1.9	-2.2	-2.2	-1.9	4.7	-2.0	0.4
Pulse wave peak to peak time	0.8	0.9	2.5	1.6	0.9	1.0	1.2	1.0	0.9	0.9	1.0	0.9	0.3	0.9	0.8
Risk taking	0.8	1.1	3.4	1.9	1.1	1.2	1.4	1.0	1.1	0.8	1.1	1.0	0.3	1.1	-0.4
Depression (Nagel 2018)	0.7	1.1	1.7	-0.3	-1.1	-1.2	-1.2	-1.2	-1.2	-1.0	-1.0	-1.3	1.1	-1.0	1.0
Ovarian Cancer	0.7	0.9	2.7	-1.4	0.8	0.9	0.7	0.8	0.8	1.0	0.8	0.8	-1.6	0.9	0.4
Fed-up feelings	0.7	1.2	2.2	-0.1	-1.3	-1.2	-1.3	-1.3	-1.5	-1.1	-1.2	-1.5	1.1	-1.1	-0.3
Hair/balding pattern: Pattern 2	0.7	0.9	1.9	-1.3	1.0	0.9	0.6	1.0	1.1	1.4	1.1	1.0	0.3	1.0	0.8
Financial difficulties in last 2 years	0.7	0.9	9.6	-0.2	0.5	0.4	0.2	0.5	0.4	0.6	0.6	0.4	0.7	0.6	3.1
Weight	0.7	3.4	23.5	-0.6	-1.5	-1.3	-1.3	-1.3	-1.6	-1.8	-1.5	-1.5	4.8	-1.4	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.7	0.8	1.5	-0.3	1.2	1.0	0.4	1.1	1.2	1.1	1.2	1.1	-0.2	1.2	0.6
Pulse wave Arterial Stiffness index	0.7	0.9	2.0	-1.4	-0.9	-1.0	-1.2	-1.0	-0.9	-0.9	-1.0	-1.0	-0.3	-0.9	-0.7
Exposure to tobacco smoke at home	0.7	0.8	1.4	-0.3	-1.0	-1.0	-0.7	-1.1	-1.1	-1.2	-1.1	-1.0	0.6	-1.1	-0.9
Loud music exposure frequency	0.7	0.8	2.9	-0.7	0.9	0.8	0.6	0.8	0.9	1.2	1.1	0.8	0.5	0.9	1.7
Mouth/teeth dental problems: Bleeding gums	0.7	0.9	2.2	1.5	1.0	1.0	0.9	1.0	1.1	1.1	1.1	1.1	-0.6	1.0	0.2
Number of children fathered	0.7	0.7	1.8	-1.2	-0.8	-0.9	-1.3	-0.7	-0.8	-0.6	-0.7	-0.7	1.4	-0.7	-0.6
Qualifications: NVQ or HND or HNC or equivalent	0.7	0.9	2.0	-0.4	1.0	1.0	0.9	1.0	1.0	1.4	1.1	1.0	-0.9	1.1	0.4
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.4	0.4	-1.0	-1.0	-1.1	-0.9	-1.0	-1.1	-0.9	-0.9	1.2	-0.9	-0.0
Whole body fat-free mass	0.7	4.0	22.1	-0.8	-1.8	-1.7	-1.8	-1.8	-1.8	-2.0	-2.0	-1.7	4.7	-1.8	0.3
Whole body water mass	0.7	4.1	23.0	-0.9	-1.8	-1.7	-1.8	-1.8	-1.8	-2.1	-2.0	-1.7	4.8	-1.8	0.3
Basal metabolic rate	0.7	4.0	23.0	-0.8	-1.7	-1.6	-1.7	-1.7	-1.8	-2.0	-1.9	-1.7	4.8	-1.7	0.4
Leg fat percentage (left)	0.7	2.4	11.1	-1.7	-1.5	-1.2	-1.1	-1.1	-1.6	-1.3	-1.3	-1.5	3.3	-1.2	-1.3
Leg fat mass (left)	0.7	2.8	17.1	-1.3	-1.5	-1.2	-1.2	-1.2	-1.6	-1.5	-1.4	-1.4	4.1	-1.2	-0.6
Bipolar Disorder (2018)	0.6	0.9	3.7	1.9	0.7	0.8	1.3	0.7	0.7	0.5	0.7	0.8	0.8	0.6	1.4
Schizophrenia vs Biploar Disorder	0.6	0.8	2.9	-1.7	-0.6	-0.7	-1.1	-0.7	-0.6	-0.2	-0.6	-0.7	0.8	-0.6	-1.6
HDL Cholesterol	0.6	1.0	1.8	-1.3	-1.1	-1.1	-1.1	-1.0	-1.2	-0.8	-1.0	-1.2	0.9	-1.0	-0.8
Qualifications: CSEs or equivalent	0.6	0.8	1.5	0.2	-1.0	-1.2	-1.1	-1.0	-1.0	-1.1	-1.1	-1.0	0.9	-1.1	0.3
Allergy	0.6	1.5	2.7	-1.2	-1.3	-1.1	-0.7	-1.4	-1.4	-1.1	-1.5	-1.4	1.6	-1.4	-0.8
Neuroticism score	0.6	1.2	2.0	0.8	-1.3	-1.3	-1.4	-1.3	-1.4	-1.2	-1.1	-1.3	0.5	-1.2	0.8
Pulse wave reflection index	0.6	0.7	2.5	1.0	0.8	1.0	1.6	0.7	0.8	0.5	0.7	0.8	-1.0	0.7	-0.6
Medication for cholesterol, blood pressure or diabetes	0.6	0.9	4.1	0.4	0.9	1.0	1.1	0.8	0.9	0.8	0.9	1.0	-0.7	0.8	2.0
Wheeze or whistling in the chest in last year	0.6	1.1	2.0	-0.5	-1.3	-1.2	-1.3	-1.1	-1.3	-1.4	-1.1	-1.3	0.9	-1.1	-0.4
Age at first live birth	0.6	1.1	1.6	-1.2	-1.1	-1.2	-1.3	-1.2	-1.1	-0.9	-1.2	-1.1	0.4	-1.2	0.7
Leg fat mass (right)	0.6	2.4	15.3	-1.3	-1.4	-1.1	-1.1	-1.1	-1.5	-1.3	-1.3	-1.4	3.9	-1.1	-0.7
Comparative height size at age 10	0.6	3.5	5.6	1.1	-2.1	-2.1	-1.7	-2.2	-2.1	-2.4	-2.4	-2.0	1.2	-2.2	1.1
Medication for cholesterol	0.6	1.0	1.8	-1.0	1.1	1.0	0.9	0.9	1.2	1.3	1.0	1.1	-1.2	1.0	0.4
Illnesses of father: None of the above (group 1)	0.6	0.7	2.4	0.9	0.7	0.9	1.0	0.8	0.7	0.7	0.7	0.7	-1.0	0.8	1.6
Ever smoked	0.6	1.1	2.7	0.2	1.0	1.4	1.7	1.2	1.1	1.2	1.1	1.0	-0.4	1.2	0.6
Diastolic blood pressure, automated reading	0.6	1.8	3.4	-1.8	-1.3	-1.4	-1.8	-1.2	-1.3	-1.4	-1.2	-1.3	1.8	-1.2	-0.5
Heart disease (siblings)	0.6	0.7	1.2	0.3	0.9	1.1	1.0	1.0	0.9	0.9	1.0	1.0	-0.1	0.9	-1.0
Alzheimer’s Disease (in mother)	0.5	0.6	1.1	0.6	-0.7	-0.8	-1.0	-0.7	-0.7	-0.7	-0.6	-0.8	1.0	-0.6	0.8
Crohns Disease (2012)	0.5	0.8	1.3	0.1	-1.0	-1.0	-1.1	-1.1	-1.1	-0.9	-1.0	-1.1	0.5	-1.0	0.5
LDL Cholesterol	0.5	0.8	1.2	0.9	1.0	1.1	1.1	1.0	1.1	0.6	1.0	0.9	0.6	1.0	0.4
Heel T-Score	0.5	4.2	9.4	1.7	2.4	2.0	1.2	1.9	2.5	2.1	2.3	2.4	-3.1	2.1	0.8
Body mass index (BMI)	0.5	2.1	14.9	-1.2	-1.0	-0.8	-0.8	-0.7	-1.2	-1.3	-0.9	-1.0	3.9	-0.8	-1.3
Waist circumference	0.5	1.8	13.8	-0.7	-1.1	-0.9	-1.0	-0.8	-1.2	-1.2	-1.0	-1.0	3.7	-0.9	0.1
Hearing difficulty/problems with background noise	0.5	0.8	3.6	1.6	0.6	0.6	0.7	0.6	0.7	0.6	0.9	0.5	-0.6	0.8	1.9
Lung cancer (father)	0.5	0.6	2.1	-1.4	-0.8	-0.8	-0.8	-0.8	-0.7	-0.8	-0.9	-0.8	0.1	-0.8	-0.5
Blood clot in the leg (DVT)	0.5	0.7	3.4	1.2	0.6	0.6	0.7	0.7	0.5	0.3	0.5	0.7	-0.8	0.6	1.8
Leg fat percentage (right)	0.5	2.0	9.4	-1.7	-1.3	-1.0	-1.0	-0.9	-1.4	-1.0	-1.1	-1.3	3.1	-1.0	-1.5
Worry too long after embarrassment	0.5	0.8	4.8	1.2	0.7	0.6	0.2	0.7	0.7	0.8	0.8	0.8	-2.2	0.7	0.6
Medication: Blood pressure	0.5	1.0	2.3	-1.0	-0.9	-0.9	-1.0	-0.9	-0.8	-0.8	-0.9	-1.0	1.4	-0.8	-1.5
Whole body fat mass	0.5	2.2	15.8	-0.9	-1.2	-1.0	-0.9	-0.9	-1.3	-1.3	-1.1	-1.2	4.0	-1.0	-0.4
Leg pain on walking	0.5	0.6	2.6	1.6	0.4	0.5	0.7	0.5	0.5	0.3	0.6	0.4	0.5	0.5	1.6
Forced expiratory volume in 1-second (FEV1), predicted	0.5	1.1	1.8	0.3	-1.1	-1.2	-1.0	-1.3	-1.1	-1.2	-1.3	-1.1	1.1	-1.3	0.8
Leg predicted mass (right)	0.5	2.5	16.1	-0.1	-1.3	-1.2	-1.1	-1.3	-1.4	-1.7	-1.5	-1.2	4.0	-1.4	0.5
Mother’s age at death	0.5	0.6	1.1	0.3	0.9	0.8	0.7	0.8	1.0	0.6	0.9	0.9	-0.5	0.9	1.1
High cholesterol (Self-reported)	0.5	0.8	1.6	0.2	-1.1	-1.1	-1.0	-1.0	-1.2	-1.3	-1.1	-1.1	0.5	-1.0	-0.1
Worry (Nagel 2018)	0.4	0.8	3.1	0.7	-0.8	-0.8	-0.7	-0.8	-0.9	-0.9	-0.7	-0.8	-0.7	-0.8	1.8
Alzheimer’s Disease (in father)	0.4	0.4	1.0	-0.8	-0.7	-0.5	-0.1	-0.7	-0.6	-0.5	-0.7	-0.6	0.8	-0.7	1.0
Body Mass Index (BMI) (2010)	0.4	0.5	2.8	0.3	-0.6	-0.6	-0.6	-0.6	-0.6	-0.8	-0.6	-0.6	1.7	-0.5	0.1
Rheumatoid Arthritis	0.4	0.5	0.9	0.7	0.8	0.8	0.7	0.8	0.7	0.9	0.9	0.8	-0.3	0.8	-0.0
Lung FEV1/FVC ratio	0.4	2.3	3.5	1.3	1.7	1.7	1.6	1.7	1.6	1.9	1.8	1.7	-0.1	1.7	-1.1
Tanning	0.4	5.0	13.7	-3.7	-2.1	-2.2	-2.4	-2.2	-2.1	-2.3	-2.3	-2.2	2.5	-2.0	-0.9
Average weekly spirits intake	0.4	0.6	1.0	0.6	-0.9	-0.8	-0.4	-0.8	-1.0	-0.8	-1.0	-0.9	0.5	-0.9	0.1
Leg fat-free mass (left)	0.4	2.3	16.5	-0.1	-1.2	-1.1	-1.1	-1.1	-1.3	-1.6	-1.3	-1.1	4.1	-1.2	0.2
Heel bone mineral density (BMD) T-score, automated (left)	0.4	1.0	1.7	-0.5	1.2	0.9	0.4	0.9	1.1	1.2	1.0	1.1	-1.3	1.0	-1.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	0.7	-0.3	0.6	0.7	0.6	0.8	0.6	0.8	0.9	0.6	0.8	0.7	-0.1
Chronic bronchitis/emphysema (father)	0.4	0.4	1.6	-0.5	-0.7	-0.7	-0.7	-0.7	-0.6	-0.6	-0.5	-0.7	0.2	-0.6	-1.3
Leg predicted mass (left)	0.4	2.2	16.0	-0.1	-1.1	-1.0	-1.0	-1.1	-1.2	-1.5	-1.3	-1.1	4.0	-1.2	0.2
Trunk fat mass	0.4	1.5	12.6	-0.3	-0.9	-0.7	-0.6	-0.7	-1.1	-1.1	-0.9	-0.9	3.5	-0.8	-0.2
Father’s age at death	0.4	0.6	1.1	-0.2	1.0	0.8	0.8	0.8	1.1	0.6	0.8	1.0	-0.4	0.8	0.0
Frequency of tiredness / lethargy in last 2 weeks	0.4	0.6	4.7	1.2	-0.5	-0.3	-0.0	-0.3	-0.6	-0.4	-0.4	-0.4	0.4	-0.5	2.2
Falls in the last year	0.4	0.6	0.9	0.8	-0.7	-0.8	-0.9	-0.8	-0.7	-0.9	-0.7	-0.7	-0.8	-0.7	-0.8
Noisy workplace	0.4	0.5	3.6	-1.9	0.4	0.5	0.4	0.6	0.5	0.8	0.6	0.4	-0.5	0.6	0.3
Asthma	0.4	0.7	3.3	1.2	0.7	0.7	0.5	0.7	0.8	0.5	0.8	0.8	-1.8	0.7	0.1
Heart disease (mother)	0.4	0.5	2.0	1.3	0.6	0.5	0.7	0.5	0.5	0.4	0.6	0.6	-1.4	0.5	0.5
Number of full sisters	0.4	0.5	1.0	-0.1	-0.8	-0.5	0.2	-0.8	-0.8	-1.0	-0.7	-1.0	1.0	-0.7	0.1
Leg fat-free mass (right)	0.4	2.4	15.6	-0.0	-1.2	-1.1	-1.1	-1.2	-1.3	-1.7	-1.4	-1.1	4.0	-1.3	0.5
Eye problems/disorders: Cataract	0.4	0.4	0.9	0.5	0.8	0.8	0.9	0.7	0.6	0.7	0.7	0.7	-0.1	0.8	0.4
Arm fat mass (left)	0.4	1.6	14.4	-0.4	-0.8	-0.6	-0.5	-0.6	-1.0	-1.1	-0.7	-0.8	3.8	-0.7	-0.6
Average weekly champagne plus white wine intake	0.4	0.5	1.5	-0.8	-0.6	-0.8	-1.0	-0.6	-0.5	-0.9	-0.6	-0.5	1.2	-0.6	-0.6
Pain type(s) experienced in last month: Hip pain	0.4	0.5	0.8	-0.4	-0.8	-0.7	-0.6	-0.8	-0.9	-0.7	-0.8	-0.8	-0.7	-0.7	-0.2
Medication: Atorvastatin	0.4	0.5	1.9	1.4	0.6	0.6	0.6	0.7	0.4	0.5	0.5	0.6	-1.2	0.6	0.8
Average weekly beer plus cider intake	0.4	0.6	0.9	-0.5	-0.9	-0.9	-0.7	-0.9	-0.9	-1.0	-0.9	-0.9	0.3	-0.9	0.8
Commuting to job workplace: Cycle	0.4	0.4	4.7	-0.7	0.1	0.2	0.4	0.1	0.1	0.2	0.1	0.1	-0.0	0.1	-2.2
Deep venous thrombosis (DVT) (self-reported)	0.4	0.5	2.5	1.2	0.4	0.5	0.7	0.5	0.3	0.1	0.4	0.5	-0.5	0.4	1.6
Impedance of whole body	0.4	2.2	12.5	1.3	1.1	1.0	1.2	1.1	1.1	1.5	1.1	1.1	-3.5	1.0	1.5
Intelligence (Savage-Jansen 2018)	0.3	1.0	2.3	-0.9	1.1	1.1	0.7	1.0	1.2	0.9	1.0	1.2	1.5	1.0	-0.2
Verbal and Numeric Reasoning (VNR)	0.3	0.6	4.1	-2.0	-0.1	-0.2	-0.6	-0.2	-0.1	0.0	-0.2	-0.1	1.8	-0.1	-0.7
BMI	0.3	1.7	16.2	-0.6	-0.8	-0.6	-0.3	-0.6	-0.9	-1.2	-0.8	-0.8	4.0	-0.7	-0.9
Cardiovascular Disease	0.3	1.0	2.3	0.8	-1.0	-1.1	-0.9	-1.0	-1.1	-1.3	-1.0	-1.1	1.5	-0.9	-0.7
Chronotype (morning person)	0.3	0.6	3.7	0.1	-0.6	-0.5	-0.5	-0.6	-0.5	-0.8	-0.5	-0.6	0.8	-0.6	-1.9
Ever used hormone-replacement therapy (HRT)	0.3	0.4	1.2	1.1	0.6	0.6	0.5	0.5	0.7	0.4	0.5	0.5	-0.9	0.6	0.9
Diabetes (father)	0.3	0.4	2.2	-0.6	-0.6	-0.6	-0.5	-0.5	-0.6	-0.6	-0.5	-0.5	1.5	-0.5	0.3
Stomach or abdominal pain in last month	0.3	0.4	1.3	1.1	-0.5	-0.5	-0.9	-0.3	-0.7	-0.8	-0.5	-0.4	0.6	-0.5	0.8
Supplements: Glucosamine	0.3	0.4	2.0	1.3	0.4	0.2	-0.3	0.3	0.4	0.3	0.5	0.4	-1.4	0.4	0.6
Frequency of tenseness / restlessness in last 2 weeks	0.3	0.4	1.6	1.3	0.4	0.5	0.5	0.6	0.4	0.5	0.6	0.5	-0.4	0.5	1.1
Heart attack	0.3	0.3	1.1	-1.1	-0.5	-0.5	-0.7	-0.4	-0.5	-0.2	-0.4	-0.5	0.8	-0.3	-0.9
Hayfever/allergic rhinitis (self-reported)	0.3	0.4	1.8	-1.3	-0.6	-0.5	-0.5	-0.4	-0.6	-0.4	-0.5	-0.5	0.8	-0.5	0.3
Hair/balding pattern: Pattern 3	0.3	0.4	1.9	-0.5	-0.6	-0.5	-0.3	-0.6	-0.7	-0.5	-0.6	-0.6	-0.6	-0.6	-1.4
Arm fat mass (right)	0.3	1.3	13.9	-0.4	-0.6	-0.4	-0.4	-0.3	-0.7	-0.9	-0.5	-0.5	3.7	-0.4	-0.2
Breastfed as a baby	0.3	0.4	0.8	0.3	0.7	0.7	0.7	0.6	0.7	0.4	0.5	0.7	-0.3	0.6	-0.9
Medication: Amlodipine	0.3	0.4	1.8	1.0	0.4	0.4	0.4	0.4	0.4	0.5	0.5	0.5	-0.8	0.4	-1.3
Chronic bronchitis/emphysema (mother)	0.3	0.4	1.7	1.2	0.3	0.3	0.7	0.3	0.4	0.1	0.2	0.3	-1.3	0.3	0.6
Number of full brothers	0.3	0.4	4.2	0.6	-0.3	-0.2	-0.4	-0.1	-0.2	-0.5	-0.3	-0.2	0.6	-0.2	2.0
Migraine (self-reported)	0.3	0.4	4.4	-0.3	0.1	-0.1	0.0	-0.0	0.1	0.4	0.1	-0.0	0.2	0.1	2.1
Hypertension (Self-reported)	0.3	0.8	3.9	0.3	-0.6	-0.8	-1.0	-0.7	-0.7	-0.8	-0.6	-0.7	2.0	-0.5	-1.2
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.3	0.3	2.3	0.4	-0.3	-0.2	-0.3	-0.1	-0.3	-0.6	-0.1	-0.3	1.0	-0.1	-1.5
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.4	1.3	0.6	-0.6	-0.4	-0.4	-0.5	-0.5	-0.8	-0.5	-0.6	1.1	-0.5	0.5
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	4.0	-0.7	-0.4	-0.4	-0.4	-0.5	-0.3	-0.2	-0.5	-0.4	-0.3	-0.4	-2.0
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.3	0.4	3.9	2.0	-0.2	-0.2	0.1	-0.2	-0.3	-0.3	-0.3	-0.2	-0.3	-0.3	0.3
Back pain experienced in last month	0.3	0.4	1.7	-0.2	0.6	0.6	0.3	0.7	0.6	0.6	0.7	0.5	-0.7	0.8	1.3
Asthma (self-reported)	0.3	0.5	3.1	0.9	0.6	0.5	0.3	0.6	0.7	0.4	0.6	0.7	-1.8	0.6	0.1
Tinnitus: Yes, now most or all of the time	0.3	0.4	0.9	-0.1	-0.6	-0.7	-0.9	-0.6	-0.7	-0.6	-0.5	-0.7	0.5	-0.6	-1.0
Eye problems/disorders: Glaucoma	0.3	0.3	1.0	0.3	0.5	0.7	0.7	0.5	0.4	0.3	0.5	0.4	0.6	0.5	-1.0
Medication: Lisinopril	0.3	0.4	0.7	0.6	0.8	0.6	0.2	0.7	0.8	0.7	0.8	0.7	-0.8	0.9	-0.0
Alcohol drinker status: Never	0.3	0.3	1.5	1.2	0.5	0.6	0.4	0.6	0.5	0.5	0.6	0.6	-0.1	0.5	0.5
Number of operations (self-reported)	0.3	0.4	1.8	1.0	0.4	0.2	0.2	0.3	0.5	0.5	0.3	0.3	-1.1	0.4	1.4
Age started oral contraceptive pill	0.3	0.4	1.1	0.0	0.7	0.6	0.4	0.7	0.8	1.0	0.8	0.7	0.7	0.7	-0.1
Major Depression (MDD)	0.2	0.2	0.4	-0.7	-0.5	-0.3	-0.1	-0.3	-0.5	-0.5	-0.5	-0.2	0.6	-0.5	-0.6
Mean Putamen Volume	0.2	0.3	1.7	-0.8	0.3	0.2	0.2	0.2	0.4	0.3	0.4	0.3	-1.3	0.3	0.8
Lupus	0.2	0.4	1.8	1.4	0.3	0.4	0.4	0.4	0.4	0.5	0.5	0.3	-1.1	0.4	0.0
Blood Eosinophil Count	0.2	1.3	1.9	-1.0	-1.3	-1.3	-1.3	-1.4	-1.3	-1.2	-1.3	-1.4	0.7	-1.3	0.1
Height	0.2	4.1	12.2	1.3	-1.9	-1.8	-1.4	-1.9	-1.8	-2.0	-2.2	-1.8	3.5	-2.0	2.8
Waist Hip Ratio (WHR)	0.2	0.7	6.4	0.5	0.4	0.3	0.3	0.5	0.2	0.7	0.5	0.4	-0.8	0.4	2.5
Smoking Status	0.2	0.4	1.7	-0.6	0.4	0.7	0.9	0.5	0.4	0.9	0.6	0.2	0.4	0.6	1.3
Allergy or Eczema	0.2	0.4	1.8	0.6	0.5	0.4	0.2	0.5	0.7	0.2	0.6	0.5	-1.0	0.5	1.4
Frequency of depressed mood in last 2 weeks	0.2	0.3	1.1	1.1	-0.5	-0.3	-0.3	-0.5	-0.6	-0.4	-0.3	-0.6	0.2	-0.4	0.9
Hearing difficulty/problems: Yes	0.2	0.3	2.2	0.5	-0.4	-0.5	-0.5	-0.4	-0.4	-0.2	-0.2	-0.4	0.3	-0.3	1.5
Trunk fat percentage	0.2	0.6	6.1	-0.1	-0.5	-0.3	-0.0	-0.2	-0.7	-0.6	-0.4	-0.4	2.5	-0.4	-0.4
Bilateral oophorectomy (both ovaries removed)	0.2	0.3	0.5	0.5	0.6	0.5	0.4	0.5	0.6	0.4	0.7	0.5	0.6	0.6	0.3
Medication: Levothyroxine sodium	0.2	0.3	1.0	1.0	0.5	0.4	0.2	0.4	0.5	0.5	0.6	0.4	-0.6	0.6	0.8
High blood pressure (mother)	0.2	0.3	1.4	0.6	0.6	0.5	0.6	0.4	0.6	0.1	0.3	0.5	-1.2	0.4	-0.1
Alcohol usually taken with meals	0.2	0.3	2.7	1.6	0.3	0.1	-0.2	0.0	0.3	-0.3	0.3	0.2	0.6	0.1	-0.5
Forced vital capacity (FVC)	0.2	0.6	6.6	-0.2	-0.2	-0.2	-0.0	-0.3	-0.2	-0.0	-0.4	-0.2	0.8	-0.3	2.6
Ever unenthusiastic/disinterested for a whole week	0.2	0.3	0.9	-0.4	-0.6	-0.5	-0.4	-0.5	-0.6	-0.5	-0.4	-0.5	0.2	-0.5	-0.9
Qualifications: A levels/AS levels or equivalent	0.2	0.3	0.9	0.4	0.6	0.6	1.0	0.5	0.6	0.6	0.6	0.6	-0.5	0.4	0.7
Depression (self-reported)	0.2	0.3	2.0	0.5	-0.4	-0.5	-0.6	-0.4	-0.5	-0.3	-0.5	-0.4	0.2	-0.4	1.4
Standing height	0.2	2.1	7.1	1.0	-1.1	-1.1	-1.0	-1.3	-1.1	-1.4	-1.5	-1.0	2.7	-1.3	2.4
Length of working week for main job	0.2	0.2	0.8	0.8	0.3	0.3	0.1	0.4	0.3	0.3	0.4	0.4	-0.8	0.4	0.9
Birth weight of first child	0.2	0.4	2.2	1.2	-0.3	-0.2	0.1	-0.2	-0.4	-0.6	-0.4	-0.2	0.1	-0.3	1.5
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	0.9	-0.5	0.6	0.5	0.4	0.6	0.6	0.6	0.5	0.6	1.0	0.5	0.8
Medication: Paracetamol	0.2	0.4	2.8	-0.2	-0.6	-0.4	-0.4	-0.4	-0.7	-0.1	-0.3	-0.6	-0.3	-0.4	1.7
Headache pain in last month	0.2	0.4	2.0	0.1	-0.6	-0.6	-0.4	-0.5	-0.8	-0.8	-0.5	-0.7	-0.0	-0.5	1.4
Glaucoma (self-reported)	0.2	0.2	1.2	-0.5	0.2	0.3	0.3	0.3	0.2	0.2	0.3	0.2	1.1	0.3	-0.5
Forced vital capacity (FVC), Best measure	0.2	0.7	4.9	0.6	0.7	0.6	0.7	0.6	0.7	0.7	0.5	0.7	-0.2	0.6	2.2
Body fat percentage	0.2	0.9	7.8	-0.7	-0.7	-0.4	-0.2	-0.4	-0.8	-0.7	-0.6	-0.7	2.8	-0.5	-0.6
Exposure to tobacco smoke outside home	0.2	0.3	0.8	-0.9	-0.4	-0.4	-0.2	-0.4	-0.5	-0.5	-0.6	-0.5	0.9	-0.4	0.5
Comparative body size at age 10	0.2	0.6	4.7	0.4	-0.7	-0.3	0.0	-0.3	-0.8	-0.7	-0.4	-0.6	0.6	-0.4	-2.2
Chest pain or discomfort	0.2	0.2	1.5	1.0	0.1	0.1	0.3	0.3	0.1	-0.0	0.2	0.1	-0.3	0.2	1.2
Had major operations	0.2	0.3	1.0	-0.6	-0.2	-0.3	-0.8	-0.3	-0.1	-0.1	-0.1	-0.2	-1.0	-0.2	-1.0
Supplements: Vitamin C	0.2	0.2	0.8	0.4	0.5	0.5	0.1	0.6	0.4	0.5	0.6	0.4	-0.4	0.6	0.9
Illnesses of father: Heart disease	0.2	0.2	0.8	-0.1	0.5	0.2	0.2	0.5	0.4	0.4	0.5	0.5	-0.5	0.5	-0.9
Loneliness, isolation	0.2	0.2	1.7	0.1	-0.4	-0.3	-0.0	-0.4	-0.5	-0.2	-0.3	-0.5	0.0	-0.4	1.3
Ever had bowel cancer screening	0.2	0.2	1.4	0.6	0.2	0.1	-0.2	0.0	0.3	0.4	0.3	0.1	-1.2	0.2	0.5
Diabetes diagnosed by doctor	0.2	0.3	0.7	0.9	0.5	0.6	0.1	0.7	0.5	0.6	0.6	0.5	0.3	0.8	-0.1
Medication: Aspirin	0.2	0.2	1.3	-0.5	-0.3	-0.3	-0.3	-0.3	-0.4	-0.4	-0.5	-0.3	-0.4	-0.3	-1.2
Number of self-reported non-cancer illnesses	0.2	0.4	3.3	1.8	0.3	0.2	-0.2	0.4	0.3	0.3	0.5	0.2	-0.5	0.5	1.0
Guilty feelings	0.2	0.3	0.8	0.9	-0.5	-0.4	-0.1	-0.5	-0.5	-0.6	-0.5	-0.5	0.0	-0.5	0.8
Medication: Blood pressure	0.2	0.3	2.3	1.5	0.1	-0.1	-0.3	0.0	0.0	-0.4	0.1	0.0	1.1	0.1	0.6
Fractured/broken bones in last 5 years	0.2	0.3	3.1	1.8	0.2	0.2	-0.1	0.3	0.2	0.0	0.2	0.2	-0.8	0.3	0.2
Myopia	0.2	0.3	0.5	0.3	-0.5	-0.5	0.0	-0.6	-0.5	-0.7	-0.5	-0.5	0.7	-0.7	0.7
Vascular/heart problems diagnosed by doctor	0.2	0.5	2.6	-0.2	0.4	0.5	0.7	0.5	0.5	0.5	0.3	0.5	-1.6	0.3	1.5
Heart attack/myocardial infarction (self-reported)	0.2	0.2	0.9	-0.8	-0.3	-0.3	-0.6	-0.2	-0.4	-0.1	-0.3	-0.3	0.6	-0.1	-0.9
Crohns Disease (2017)	0.1	0.2	1.5	0.0	0.3	0.2	0.2	0.2	0.3	0.5	0.2	0.1	-1.0	0.3	1.2
Irritable Bowel Disease (IBD)	0.1	0.1	0.3	-0.5	0.3	0.2	-0.2	0.2	0.2	0.5	0.3	0.1	-0.6	0.3	0.6
Ulcerative Colitis (UC)	0.1	0.2	0.6	-0.8	0.4	0.3	-0.2	0.4	0.3	0.7	0.4	0.4	-0.7	0.5	0.1
Reaction Time	0.1	0.2	0.5	-0.7	-0.6	-0.4	0.1	-0.5	-0.7	-0.4	-0.6	-0.6	-0.1	-0.6	0.3
Fasting Glucose	0.1	0.2	0.6	-0.8	-0.3	-0.3	-0.5	-0.3	-0.2	-0.2	-0.3	-0.3	0.7	-0.2	0.2
Primary Biliary Cirrhosis	0.1	0.1	0.2	-0.3	-0.3	-0.3	-0.2	-0.2	-0.4	-0.2	-0.3	-0.3	0.5	-0.3	0.1
Triglycerides	0.1	0.2	1.7	0.6	0.4	0.2	-0.1	0.3	0.5	0.1	0.3	0.4	0.1	0.3	1.3
Ulcerative Colitis	0.1	0.2	1.0	0.2	0.4	0.3	0.1	0.3	0.3	0.3	0.3	0.4	-1.0	0.3	0.4
Blood Platelet Count	0.1	0.8	2.9	-1.7	-0.6	-0.9	-1.5	-0.7	-0.6	-0.4	-0.6	-0.7	1.1	-0.6	-1.0
Hypothyroidism (self reported)	0.1	0.2	1.2	1.1	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	-0.2	0.2	-0.1	0.9
Respiratory disease	0.1	0.3	2.8	0.7	0.1	0.0	-0.1	0.0	0.2	0.1	0.1	0.1	-1.7	0.1	0.1
Type 2 Diabetes (T2D) (2018)	0.1	0.2	0.9	1.0	0.3	0.2	-0.2	0.4	0.3	0.3	0.4	0.2	0.6	0.5	-0.4
Lung FVC	0.1	0.4	2.6	-0.6	0.5	0.5	0.4	0.4	0.5	0.7	0.5	0.4	0.5	0.5	1.6
Number of treatments/medications taken	0.1	0.2	0.4	0.6	-0.4	-0.5	-0.6	-0.3	-0.5	-0.5	-0.5	-0.4	-0.7	-0.3	-0.3
Medication for hormone replacement therapy	0.1	0.1	0.4	0.6	-0.4	-0.3	-0.3	-0.3	-0.4	-0.4	-0.3	-0.3	-0.0	-0.4	0.4
Medication: Co-codamol	0.1	0.1	1.5	1.2	0.0	0.0	0.0	0.1	-0.0	0.1	0.1	0.1	0.0	0.0	0.5
Medication: Metformin	0.1	0.1	0.8	0.2	-0.2	-0.2	-0.7	-0.1	-0.3	-0.2	-0.2	-0.3	0.4	-0.0	-0.9
Severe depression (siblings)	0.1	0.2	0.6	-0.8	0.3	0.3	0.3	0.3	0.3	0.5	0.5	0.1	-0.0	0.4	0.6
Pack years adult smoking proportion	0.1	0.1	1.1	-0.6	-0.1	-0.1	-0.1	-0.1	-0.3	0.1	-0.1	-0.2	1.1	-0.1	-0.1
Impedance of leg (right)	0.1	0.7	6.5	-0.1	0.1	-0.0	-0.1	0.0	0.1	0.8	0.0	0.0	-2.6	0.1	1.1
Maternal smoking around birth	0.1	0.1	0.3	0.4	-0.2	-0.3	-0.5	-0.3	-0.4	-0.0	-0.2	-0.3	-0.0	-0.1	-0.3
High blood pressure	0.1	0.4	3.1	0.5	-0.1	-0.2	-0.4	-0.2	-0.2	-0.3	-0.0	-0.2	1.8	-0.0	-1.1
Hayfever, allergic rhinitis or eczema	0.1	0.1	0.9	0.3	0.3	0.1	-0.4	0.2	0.5	0.1	0.4	0.3	-0.4	0.3	0.9
Impedance of leg (left)	0.1	0.6	4.4	-0.2	-0.3	-0.4	-0.4	-0.3	-0.3	0.4	-0.4	-0.3	-2.1	-0.3	1.3
Had menopause	0.1	0.1	0.3	0.2	0.3	0.4	0.3	0.3	0.4	0.3	0.3	0.3	-0.2	0.4	0.5
Qualifications: None of the above	0.1	0.2	0.8	0.8	0.1	0.5	0.9	0.3	0.1	0.1	0.2	0.1	-0.9	0.2	0.6
Diabetes (self-reported)	0.1	0.1	0.6	0.8	0.2	0.2	-0.4	0.4	0.1	0.2	0.3	0.1	0.7	0.5	-0.2
Medication: Ramipril	0.1	0.1	0.5	0.7	0.1	0.1	0.3	0.1	-0.0	-0.1	0.1	0.0	0.1	0.1	-0.7
Fluid intelligence score	0.1	0.2	1.9	-0.3	-0.2	-0.3	-0.3	-0.4	-0.3	-0.4	-0.3	-0.2	1.4	-0.4	0.3
Arm fat percentage (right)	0.1	0.5	4.8	-0.0	0.3	0.5	0.7	0.5	0.1	0.0	0.5	0.3	2.2	0.4	-0.6
Forced expiratory volume in 1-second (FEV1)	0.1	0.2	1.9	-0.0	0.0	0.0	0.1	-0.1	0.1	0.2	-0.1	0.0	0.6	-0.1	1.4
Medication: Lansoprazole	0.1	0.1	0.7	0.4	0.2	0.1	-0.1	0.3	0.3	-0.1	0.3	0.3	0.8	0.3	-0.4
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.3	1.7	0.3	0.5	0.4	0.5	0.3	0.5	0.6	0.3	0.4	0.2	0.3	1.3
Seen doctor (GP) for nerves, anxiety, tension or depression	0.1	0.2	1.6	0.4	-0.1	-0.2	-0.4	-0.1	-0.1	-0.2	-0.1	-0.2	0.4	0.0	1.3
Peak expiratory flow (PEF)	0.1	0.2	0.7	-0.9	-0.2	-0.3	-0.4	-0.4	-0.2	-0.2	-0.3	-0.4	0.6	-0.3	-0.5
Ever highly irritable/argumentative for 2 days	0.1	0.2	0.5	-0.0	0.4	0.4	0.2	0.4	0.3	0.7	0.5	0.3	-0.6	0.4	-0.1
Hypothyroidism/myxoedema (self-reported)	0.1	0.2	1.6	1.3	-0.2	-0.3	-0.4	-0.3	-0.2	-0.3	-0.1	-0.3	0.1	-0.2	0.7
Medication: Ventolin 100micrograms inhaler	0.1	0.1	0.5	0.1	-0.3	-0.3	-0.6	-0.2	-0.2	-0.2	-0.1	-0.2	-0.7	-0.2	0.7
Birth weight	0.1	0.3	2.2	0.1	-0.4	-0.3	-0.0	-0.3	-0.5	-0.3	-0.4	-0.4	1.5	-0.4	0.1
Qualifications: College or University degree	0.1	0.4	2.6	0.5	0.5	0.4	0.2	0.4	0.6	0.4	0.4	0.6	-1.6	0.3	0.5
Medication: Seretide 50 evohaler	0.1	0.1	0.3	-0.6	-0.2	0.0	0.2	-0.1	-0.3	-0.2	-0.3	-0.1	0.6	-0.2	0.4
Mean time to correctly identify matches	0.1	0.2	0.8	0.1	0.2	0.4	0.8	0.4	0.1	0.6	0.3	0.3	-0.9	0.3	0.6
Alcohol intake frequency.	0.1	0.2	0.7	0.3	-0.4	-0.3	-0.6	-0.2	-0.4	-0.4	-0.2	-0.3	0.8	-0.2	0.6
Medication: Aspirin	0.1	0.2	0.7	-0.4	-0.3	-0.4	-0.4	-0.4	-0.4	-0.5	-0.5	-0.3	-0.1	-0.3	-0.8
Knee pain experienced in last month	0.1	0.2	1.6	1.3	-0.1	-0.1	-0.2	-0.1	-0.2	-0.3	0.1	-0.2	-0.5	-0.0	-0.4
Illnesses of siblings: Diabetes	0.1	0.2	1.9	0.1	-0.1	-0.1	-0.1	-0.1	-0.1	-0.3	-0.1	-0.2	0.4	-0.1	1.4
Arm fat percentage (left)	0.1	0.5	5.8	-0.1	-0.0	0.2	0.5	0.3	-0.2	-0.3	0.1	0.0	2.4	0.1	-0.8
Qualifications: nursing, teaching	0.1	0.2	2.4	0.3	-0.0	-0.0	0.2	0.1	-0.1	-0.1	0.1	0.1	0.0	-0.1	-1.6
Commuting to job workplace: Walk	0.1	0.1	0.2	-0.5	-0.3	-0.3	0.0	-0.4	-0.4	-0.3	-0.5	-0.4	0.1	-0.4	-0.3
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.1	0.2	1.3	0.4	0.3	0.3	0.4	0.2	0.4	0.4	0.2	0.3	-1.1	0.2	-0.1
Medication: Paracetamol	0.1	0.2	2.0	-0.4	-0.3	-0.2	-0.2	-0.1	-0.3	0.1	-0.1	-0.2	-0.2	-0.2	1.4
Irritability	0.1	0.2	1.1	0.7	-0.4	-0.4	-0.7	-0.4	-0.4	-0.2	-0.3	-0.4	-0.3	-0.4	1.0
Ever depressed for a whole week	0.1	0.1	1.1	-0.0	0.2	0.2	0.0	0.1	0.2	0.2	0.1	0.3	-1.1	0.1	-0.3
Cholesterol lowering medication	0.1	0.2	2.2	1.5	-0.1	-0.0	0.2	-0.0	-0.3	-0.2	-0.1	-0.2	-0.2	-0.1	0.4
Basal cell carcinoma (self-reported)	0.1	0.1	0.5	-0.7	-0.0	-0.2	-0.3	-0.2	0.0	0.4	0.0	-0.1	0.6	-0.0	-0.6
Pack years of smoking	0.1	0.1	0.5	-0.5	0.2	0.2	0.1	0.2	0.1	0.4	0.2	0.1	0.7	0.3	-0.3
Prostate Cancer	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0	0.0
Blood Red Count	0.0	0.3	1.9	1.4	0.2	0.3	0.4	0.3	0.3	-0.1	0.3	0.3	0.1	0.3	-1.3
Hair Pigment	0.0	1.3	3.2	1.0	1.1	1.3	1.8	1.1	1.0	0.9	0.9	1.2	-1.4	1.0	1.1
Diabetes (mother)	0.0	0.0	0.4	-0.1	-0.0	0.1	0.0	0.0	-0.1	0.2	0.1	-0.1	0.2	0.1	0.6
Alcohol intake versus 10 years previously	0.0	0.0	0.2	0.1	-0.1	-0.1	-0.2	-0.1	-0.2	-0.1	-0.1	-0.2	0.4	0.0	-0.1
Illnesses of mother	0.0	0.1	0.4	0.6	0.1	0.1	-0.1	0.2	0.0	0.2	0.1	0.2	0.0	0.1	-0.4
Shortness of breath walking on level ground	0.0	0.0	0.5	-0.1	0.1	-0.0	-0.1	0.1	0.0	-0.2	0.0	0.1	0.1	0.1	0.7
Illnesses of father: High blood pressure	0.0	0.0	0.2	0.5	0.0	-0.0	0.2	-0.0	-0.0	-0.1	-0.1	0.0	0.5	-0.0	0.0

Hub : Genes

TPBG

Models

Trait associations