[Hub]/) : Traits : Arm predicted mass (right) :

chr7:91,142,400-93,160,671

Best TWAS P=3.88e-51 · Best GWAS P=5.64e-46 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex CDK6 0.12 0.10 lasso 2 0.10 1.9e-12 13.98 14.0 1.9e-44 0.89 0.02 0.98 FALSE
2 GTEx Adipose Visceral Omentum GATAD1 0.12 0.08 lasso 5 0.06 7.5e-04 6.74 -6.8 1.5e-11 -0.51 0.81 0.07 FALSE
3 GTEx Adrenal Gland GATAD1 0.40 0.22 lasso 7 0.25 2.0e-09 6.74 -7.5 4.3e-14 -0.57 0.63 0.13 FALSE
4 GTEx Artery Aorta KRIT1 0.15 0.00 enet 24 0.03 1.3e-02 0.74 -6.2 4.9e-10 -0.27 0.12 0.05 FALSE
5 GTEx Artery Aorta GATAD1 0.09 0.08 enet 4 0.07 7.4e-05 6.74 -6.7 2.0e-11 -0.49 0.50 0.08 FALSE
6 GTEx Artery Coronary GATAD1 0.12 0.15 lasso 3 0.12 8.0e-05 6.96 -7.2 8.8e-13 -0.54 0.18 0.25 FALSE
7 GTEx Artery Tibial GATAD1 0.14 0.04 enet 17 0.04 4.1e-04 6.74 -7.0 3.2e-12 -0.45 0.69 0.12 FALSE
8 GTEx Artery Tibial AC007566.10 0.13 0.04 lasso 5 0.00 3.1e-01 5.71 -6.3 2.2e-10 -0.10 0.08 0.04 FALSE
9 GTEx Brain Caudate basal ganglia GATAD1 0.21 0.09 lasso 4 0.08 2.3e-03 5.33 -7.8 9.3e-15 -0.56 0.06 0.44 FALSE
10 GTEx Breast Mammary Tissue (Female) AC007566.10 0.04 -0.01 lasso 2 0.01 2.0e-01 1.13 -6.8 1.3e-11 -0.32 0.03 0.19 FALSE
11 GTEx Cells Transformed fibroblasts GATAD1 0.23 0.20 lasso 4 0.22 1.4e-16 6.74 -9.1 8.0e-20 -0.69 0.94 0.06 FALSE
12 GTEx Colon Transverse GATAD1 0.13 0.00 enet 16 0.05 3.0e-03 6.74 -7.8 4.7e-15 -0.52 0.18 0.25 FALSE
13 GTEx Esophagus Mucosa GATAD1 0.16 0.05 enet 16 0.08 7.3e-06 6.74 -7.2 5.9e-13 -0.46 0.72 0.16 FALSE
14 GTEx Esophagus Muscularis GATAD1 0.18 0.10 enet 33 0.13 1.6e-08 6.74 -5.8 6.4e-09 -0.38 0.97 0.00 FALSE
15 GTEx Esophagus Muscularis FAM133B 0.07 0.01 enet 2 0.01 1.2e-01 -9.54 -9.5 2.5e-21 -0.55 0.07 0.34 FALSE
16 GTEx Lung GATAD1 0.15 0.12 lasso 2 0.11 1.1e-08 6.74 -6.7 1.8e-11 -0.53 0.99 0.00 FALSE
17 GTEx Muscle Skeletal PEX1 0.06 0.03 lasso 5 0.02 2.7e-03 5.72 6.2 7.4e-10 0.42 0.45 0.27 FALSE
18 GTEx Muscle Skeletal GATAD1 0.05 0.00 enet 13 0.01 2.4e-02 2.90 -6.9 5.9e-12 -0.44 0.46 0.05 FALSE
19 GTEx Nerve Tibial GATAD1 0.30 0.19 lasso 5 0.23 1.8e-16 6.74 -5.2 2.7e-07 -0.44 1.00 0.00 FALSE
20 GTEx Pancreas GATAD1 0.12 0.13 lasso 2 0.14 2.0e-06 6.74 -6.1 1.3e-09 -0.49 0.11 0.67 FALSE
21 GTEx Skin Not Sun Exposed Suprapubic GATAD1 0.22 0.27 lasso 4 0.26 1.1e-14 6.74 -6.9 4.9e-12 -0.53 1.00 0.00 FALSE
22 GTEx Skin Sun Exposed Lower leg PEX1 0.18 0.06 enet 41 0.03 1.5e-03 -7.69 -8.0 1.3e-15 -0.44 0.20 0.15 FALSE
23 GTEx Skin Sun Exposed Lower leg GATAD1 0.30 0.10 enet 14 0.16 7.0e-13 6.74 -6.8 1.3e-11 -0.44 1.00 0.00 FALSE
24 GTEx Spleen PEX1 0.18 0.00 enet 38 0.05 2.4e-02 3.67 -7.2 7.8e-13 -0.38 0.08 0.11 FALSE
25 GTEx Stomach GATAD1 0.30 0.13 lasso 5 0.15 8.6e-08 6.74 -6.8 9.6e-12 -0.52 0.97 0.00 FALSE
26 GTEx Testis CDK6 0.10 0.10 lasso 3 0.09 8.0e-05 14.23 -15.0 3.9e-51 -0.96 0.01 0.99 TRUE
27 GTEx Thyroid GATAD1 0.18 0.06 lasso 4 0.06 3.3e-05 6.74 -6.6 5.4e-11 -0.48 0.95 0.02 FALSE
28 METSIM Adipose GATAD1 0.10 0.05 lasso 7 0.06 9.4e-10 2.90 -5.1 2.9e-07 -0.40 1.00 0.00 FALSE
29 ROSMAP Brain Pre-frontal Cortex KRIT1 0.04 0.03 bslmm 311 0.01 9.0e-03 3.67 7.0 2.6e-12 0.51 0.74 0.06 FALSE
30 ROSMAP Brain Pre-frontal Cortex GATAD1 0.17 0.15 lasso 4 0.16 6.0e-20 6.84 -6.8 7.3e-12 -0.51 1.00 0.00 FALSE
31 YFS Blood GATAD1 0.01 0.01 blup 297 0.01 5.1e-04 6.74 -8.8 9.4e-19 -0.53 0.74 0.09 FALSE
32 The Cancer Genome Atlas Breast Invasive Carcinoma GATAD1 0.06 0.04 lasso 6 0.04 2.2e-09 6.54 -6.2 6.0e-10 -0.40 0.60 0.40 FALSE
33 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GATAD1 0.04 0.04 lasso 2 0.03 2.8e-04 6.54 -6.3 2.7e-10 -0.47 0.14 0.16 FALSE
34 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma C7orf64 0.06 0.02 blup 36 0.02 6.0e-02 5.84 5.2 1.9e-07 0.42 0.04 0.06 FALSE