Best TWAS P=1.9e-07 · Best GWAS P=5.1e-10 conditioned to 5.52e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | CASC10 | 0.05 | 0.06 | lasso | 4 | 0.02 | 0.0131 | 4.2 | 5.2 | 1.9e-07 | 0.54 | 0.27 | 0.45 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | MLLT10 | 0.06 | 0.02 | lasso | 4 | 0.03 | 0.0008 | 5.1 | -5.2 | 2.1e-07 | -0.80 | 0.18 | 0.79 | FALSE |
| 3 | GTEx | Skin Sun Exposed Lower leg | CASC10 | 0.08 | 0.02 | lasso | 5 | 0.01 | 0.0614 | 4.2 | 5.2 | 2.1e-07 | 0.90 | 0.08 | 0.83 | FALSE |