Best TWAS P=1.19e-07 · Best GWAS P=6.26e-07 conditioned to 0.00742
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Artery Tibial | WAC | 0.10 | 0.00 | enet | 32 | 0.00 | 5.6e-01 | -4.8 | -5.2 | 2.2e-07 | 0.53 | 0.04 | 0.44 | FALSE |
2 | GTEx | Heart Atrial Appendage | WAC-AS1 | 0.18 | 0.12 | enet | 6 | 0.15 | 2.5e-07 | 4.5 | 5.3 | 1.2e-07 | -0.50 | 0.07 | 0.91 | TRUE |
3 | GTEx | Vagina | WAC-AS1 | 0.55 | 0.25 | lasso | 5 | 0.22 | 1.0e-05 | 4.5 | 5.2 | 1.9e-07 | -0.43 | 0.09 | 0.82 | FALSE |