[Hub]/) : Traits : Arm predicted mass (right) :

chr12:106,649,988-108,064,952

Best TWAS P=1.08e-08 · Best GWAS P=1.37e-08 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous RP11-412D9.4 0.22 0.13 lasso 5 0.13 5.1e-11 -5.1 5.6 1.8e-08 -0.94 0.02 0.98 FALSE
2 GTEx Artery Tibial RP11-412D9.4 0.06 0.05 lasso 3 0.06 2.9e-05 -5.5 5.6 2.0e-08 -0.93 0.01 0.98 FALSE
3 GTEx Breast Mammary Tissue RP11-412D9.4 0.23 0.26 lasso 4 0.26 9.7e-14 -5.5 5.4 7.8e-08 -0.97 0.00 1.00 FALSE
4 GTEx Cells Transformed fibroblasts RP11-412D9.4 0.12 0.10 lasso 4 0.09 2.1e-07 -5.1 5.7 1.5e-08 -0.91 0.01 0.99 FALSE
5 GTEx Nerve Tibial C12orf23 0.09 0.12 enet 10 0.12 1.1e-08 -5.7 5.7 1.4e-08 -0.97 0.00 1.00 FALSE
6 GTEx Nerve Tibial RP11-412D9.4 0.18 0.18 enet 11 0.20 5.6e-14 -5.1 5.5 3.2e-08 -0.95 0.01 0.99 FALSE
7 GTEx Pancreas RP11-412D9.4 0.09 0.06 enet 12 0.06 1.2e-03 -5.7 5.2 2.2e-07 -0.85 0.02 0.96 FALSE
8 GTEx Skin Sun Exposed Lower leg C12orf23 0.06 0.04 lasso 3 0.03 8.0e-04 -5.5 5.7 1.1e-08 -0.98 0.01 0.99 TRUE
9 GTEx Testis RP11-412D9.4 0.25 0.24 lasso 5 0.20 3.7e-09 -5.7 5.7 1.5e-08 -0.99 0.00 1.00 FALSE
10 GTEx Thyroid RP11-412D9.4 0.10 0.10 enet 7 0.12 9.3e-10 5.2 5.7 1.1e-08 -0.95 0.01 0.99 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma MTERFD3 0.02 0.01 lasso 4 0.01 1.3e-03 -5.1 5.6 1.6e-08 -0.89 0.02 0.90 FALSE
12 The Cancer Genome Atlas Pancreatic Adenocarcinoma C12orf23 0.06 0.05 enet 8 0.05 5.0e-03 -5.7 5.5 4.9e-08 -0.93 0.01 0.75 FALSE