[Hub]/) : Traits : Arm predicted mass (right) : ← →

chr12:109,591,369-113,517,494

Best TWAS P=3.22e-15 · Best GWAS P=3.63e-22 conditioned to 0.582

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	GTEx	Adipose Subcutaneous	HECTD4	0.06	0.00	enet	15	0.02	1.0e-02	3.19	-6.2	4.6e-10	0.65	0.06	0.84	FALSE
2	GTEx	Adrenal Gland	PPTC7	0.13	-0.01	lasso	6	0.00	3.4e-01	5.67	6.8	1.4e-11	-0.26	0.04	0.14	FALSE
3	GTEx	Artery Tibial	VPS29	0.05	0.03	lasso	3	0.02	5.9e-03	6.16	6.2	7.5e-10	-0.11	0.08	0.69	FALSE
4	GTEx	Artery Tibial	HECTD4	0.05	0.02	lasso	3	0.01	3.1e-02	-8.13	-7.9	3.2e-15	0.78	0.02	0.92	TRUE
5	GTEx	Breast Mammary Tissue (Male)	RP3-462E2.3	0.12	0.03	lasso	7	0.04	4.0e-02	3.60	5.2	2.5e-07	-0.39	0.02	0.06	FALSE
6	GTEx	Breast Mammary Tissue (Female)	VPS29	0.10	-0.01	lasso	2	0.02	1.0e-01	-5.42	6.9	5.3e-12	-0.34	0.03	0.17	TRUE
7	GTEx	Cells EBV-transformed lymphocytes	ARPC3	0.13	0.09	lasso	4	0.04	2.0e-02	5.59	-5.6	2.4e-08	0.04	0.12	0.20	FALSE
8	GTEx	Cells Transformed fibroblasts	VPS29	0.09	0.13	lasso	3	0.13	9.8e-10	6.16	5.9	3.9e-09	-0.09	0.06	0.94	FALSE
9	GTEx	Colon Transverse	FAM109A	0.21	0.00	lasso	4	0.01	1.3e-01	5.45	-6.1	8.7e-10	0.41	0.06	0.06	FALSE
10	GTEx	Esophagus Mucosa	VPS29	0.14	0.13	lasso	6	0.13	3.0e-09	5.32	5.6	2.1e-08	-0.07	0.16	0.84	FALSE
11	GTEx	Esophagus Muscularis	VPS29	0.08	0.04	lasso	4	0.03	9.0e-03	5.37	5.4	7.9e-08	-0.07	0.15	0.53	FALSE
12	GTEx	Heart Left Ventricle	ADAM1A	0.20	0.07	enet	22	0.10	4.3e-06	0.62	5.3	1.4e-07	-0.34	0.35	0.15	FALSE
13	GTEx	Lung	GPN3	0.08	0.08	enet	8	0.07	1.0e-05	4.71	-5.1	2.7e-07	0.06	0.78	0.20	FALSE
14	GTEx	Muscle Skeletal	VPS29	0.06	0.06	lasso	3	0.05	4.3e-06	6.16	6.1	1.3e-09	-0.09	0.06	0.94	FALSE
15	GTEx	Muscle Skeletal	IFT81	0.08	0.08	lasso	5	0.07	1.7e-07	5.61	5.7	1.0e-08	-0.04	0.06	0.94	FALSE
16	GTEx	Muscle Skeletal	ANAPC7	0.08	0.01	lasso	3	0.00	1.1e-01	5.23	5.9	4.2e-09	-0.07	0.03	0.77	FALSE
17	GTEx	Nerve Tibial	VPS29	0.05	0.01	lasso	4	0.00	2.5e-01	5.67	5.1	2.8e-07	-0.04	0.08	0.26	FALSE
18	GTEx	Nerve Tibial	HECTD4	0.05	0.01	enet	6	0.01	3.6e-02	5.31	-5.4	7.6e-08	0.41	0.22	0.46	FALSE
19	GTEx	Skin Not Sun Exposed Suprapubic	VPS29	0.06	0.01	lasso	3	0.01	6.9e-02	5.62	6.2	4.9e-10	-0.07	0.08	0.33	FALSE
20	GTEx	Skin Sun Exposed Lower leg	ARPC3	0.13	0.15	lasso	3	0.15	1.9e-12	5.64	-5.6	1.7e-08	0.05	0.39	0.61	FALSE
21	GTEx	Skin Sun Exposed Lower leg	VPS29	0.05	0.04	lasso	6	0.03	1.0e-03	4.80	5.5	3.8e-08	-0.10	0.14	0.60	FALSE
22	GTEx	Skin Sun Exposed Lower leg	ALDH2	0.10	0.09	enet	13	0.13	6.7e-11	2.95	-6.0	2.6e-09	0.62	0.92	0.08	FALSE
23	GTEx	Spleen	VPS29	0.24	0.01	enet	14	0.04	2.9e-02	4.69	5.2	2.0e-07	-0.02	0.08	0.15	FALSE
24	GTEx	Testis	ARPC3	0.16	0.16	lasso	3	0.14	7.5e-07	5.64	-5.6	1.7e-08	0.05	0.38	0.61	FALSE
25	GTEx	Thyroid	BRAP	0.07	0.02	lasso	7	0.03	1.1e-03	3.00	5.1	2.6e-07	-0.54	0.36	0.41	FALSE
26	GTEx	Thyroid	VPS29	0.07	0.01	lasso	5	0.01	8.9e-02	5.67	6.0	1.9e-09	-0.11	0.06	0.43	FALSE
27	GTEx	Whole Blood	GPN3	0.19	0.20	lasso	4	0.19	1.9e-17	5.67	-5.8	6.9e-09	0.10	0.20	0.80	FALSE
28	METSIM	Adipose	GPN3	0.05	0.04	enet	17	0.04	1.1e-06	5.60	-5.3	1.3e-07	0.01	0.30	0.70	FALSE
29	NTR	Blood	ALDH2	0.06	0.01	blup	222	0.02	4.3e-08	3.75	5.8	5.2e-09	-0.43	0.94	0.06	FALSE
30	NTR	Blood	GPN3	0.03	0.01	blup	236	0.02	2.7e-06	5.23	-6.5	9.8e-11	0.12	0.35	0.64	FALSE
31	YFS	Blood	GLTP	0.05	0.01	enet	14	0.04	1.5e-13	4.50	5.7	1.5e-08	-0.08	0.02	0.98	FALSE
32	YFS	Blood	SH2B3	0.05	0.01	enet	22	0.02	3.3e-07	3.00	-6.3	4.0e-10	0.64	0.70	0.30	FALSE
33	YFS	Blood	TRAFD1	0.04	0.02	lasso	2	0.01	2.9e-05	-4.51	-5.6	1.8e-08	0.55	0.09	0.85	FALSE
34	The Cancer Genome Atlas	Breast Invasive Carcinoma	VPS29	0.02	0.02	lasso	5	0.03	4.6e-06	5.67	6.1	1.4e-09	-0.07	0.00	0.99	FALSE
35	The Cancer Genome Atlas	Kidney Renal Clear Cell Carcinoma	VPS29	0.08	0.06	lasso	5	0.07	2.0e-08	5.67	5.5	4.2e-08	-0.10	0.00	1.00	FALSE
36	The Cancer Genome Atlas	Brain Lower Grade Glioma	ACAD10	0.02	0.02	lasso	3	0.01	7.0e-03	5.53	5.5	3.5e-08	-0.50	0.01	0.90	FALSE
37	The Cancer Genome Atlas	Brain Lower Grade Glioma	VPS29	0.06	0.06	enet	7	0.06	2.1e-07	5.80	6.0	2.7e-09	-0.06	0.00	1.00	FALSE
38	The Cancer Genome Atlas	Prostate Adenocarcinoma	CUX2	0.08	0.01	blup	95	0.02	1.3e-03	4.89	6.4	2.0e-10	-0.15	0.17	0.03	TRUE
39	The Cancer Genome Atlas	Thyroid Carcinoma	RAD9B	0.10	0.06	enet	5	0.06	1.2e-06	5.64	5.6	1.8e-08	-0.05	0.03	0.97	FALSE