Best TWAS P=4.97e-11 · Best GWAS P=6.11e-11 conditioned to 0.0982
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | FARP1 | 0.10 | 0.05 | enet | 5 | 0.05 | 1.4e-06 | -6.3 | 6.2 | 6.8e-10 | -0.94 | 0.02 | 0.98 | FALSE |
2 | GTEx | Adipose Subcutaneous | STK24 | 0.18 | 0.06 | lasso | 8 | 0.08 | 2.4e-07 | -4.9 | -5.7 | 9.7e-09 | 0.75 | 0.03 | 0.96 | FALSE |
3 | GTEx | Artery Tibial | STK24 | 0.12 | 0.10 | lasso | 3 | 0.08 | 8.4e-07 | -6.1 | -6.0 | 2.0e-09 | 0.85 | 0.07 | 0.93 | FALSE |
4 | GTEx | Esophagus Mucosa | FARP1-AS1 | 0.11 | 0.03 | lasso | 2 | 0.04 | 1.7e-03 | -6.3 | -6.4 | 1.7e-10 | 0.99 | 0.01 | 0.98 | FALSE |
5 | GTEx | Whole Blood | FARP1-AS1 | 0.19 | 0.07 | enet | 34 | 0.07 | 3.3e-07 | -6.3 | -5.3 | 1.0e-07 | 0.78 | 0.01 | 0.99 | FALSE |
6 | NTR | Blood | FARP1 | 0.02 | 0.01 | lasso | 3 | 0.01 | 4.3e-04 | -6.3 | -6.6 | 5.0e-11 | 0.87 | 0.02 | 0.98 | TRUE |