Best TWAS P=1.71e-08 · Best GWAS P=4.93e-07 conditioned to 0.31
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | YWHAB | 0.29 | 0.17 | lasso | 5 | 0.15 | 1.3e-08 | 5.0 | -5.1 | 2.8e-07 | -0.99 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Brain Cerebellum | YWHAB | 0.43 | 0.19 | lasso | 7 | 0.16 | 1.7e-05 | 4.9 | -5.2 | 1.7e-07 | -0.97 | 0.01 | 0.97 | FALSE |
| 3 | The Cancer Genome Atlas | Colon Adenocarcinoma | PABPC1L | 0.08 | 0.01 | enet | 8 | 0.02 | 3.6e-02 | 4.9 | -5.6 | 1.7e-08 | -0.78 | 0.01 | 0.80 | TRUE |
| 4 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | YWHAB | 0.07 | 0.06 | lasso | 2 | 0.06 | 1.3e-04 | 4.9 | -5.3 | 1.3e-07 | -0.99 | 0.01 | 0.96 | FALSE |