[Hub]/) : Traits : Arm fat percentage (left) :

chr20:46,838,455-48,603,940

Best TWAS P=1.62e-10 · Best GWAS P=1.84e-11 conditioned to 6.95e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ARFGEF2 0.09 0.05 lasso 8 0.10 9.2e-13 -6.3 6.4 1.6e-10 -0.41 0.04 0.96 TRUE
2 GTEx Colon Sigmoid CSE1L 0.18 0.12 lasso 11 0.09 4.4e-04 -5.1 5.1 2.7e-07 -0.48 0.48 0.30 FALSE
3 GTEx Skin Not Sun Exposed Suprapubic ZFAS1 0.16 0.04 enet 19 0.07 1.0e-04 -2.7 -5.4 5.1e-08 0.48 0.07 0.84 FALSE
4 GTEx Skin Sun Exposed Lower leg CSE1L 0.08 0.03 lasso 2 0.03 9.5e-04 -5.5 5.1 2.9e-07 -0.45 0.49 0.12 FALSE
5 GTEx Skin Sun Exposed Lower leg ZFAS1 0.07 0.03 enet 14 0.05 5.8e-05 -5.8 -6.0 1.8e-09 0.55 0.37 0.51 FALSE
6 GTEx Testis ARFGEF2 0.20 0.20 lasso 7 0.24 5.4e-11 -4.1 5.4 5.0e-08 -0.51 0.20 0.80 FALSE
7 METSIM Adipose ARFGEF2 0.04 0.03 lasso 12 0.02 9.8e-05 -6.2 5.6 1.7e-08 -0.50 0.18 0.80 FALSE
8 NTR Blood SNORD12B 0.03 0.05 lasso 8 0.05 1.9e-14 -5.8 5.9 3.8e-09 -0.51 0.42 0.58 FALSE
9 The Cancer Genome Atlas Brain Lower Grade Glioma ARFGEF2 0.05 0.04 lasso 5 0.05 3.2e-06 -6.3 6.3 2.6e-10 -0.58 0.04 0.96 FALSE
10 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma C20orf199 0.05 0.06 lasso 4 0.06 1.0e-04 -5.8 -5.8 8.2e-09 0.51 0.00 0.96 FALSE