[Hub]/) : Traits : Arm fat percentage (left) :

chr3:93,537,290-94,472,527

Best TWAS P=4.65e-12 · Best GWAS P=4.04e-20 conditioned to 1.06e-06

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Heart Atrial Appendage PROS1 0.31 0.16 enet 7 0.19 8.4e-09 6.6 -6.3 3.2e-10 -0.68 0.96 0.02 FALSE
2 METSIM Adipose STX19 0.06 0.09 lasso 3 0.08 1.8e-11 5.9 6.4 2.1e-10 0.50 1.00 0.00 FALSE
3 YFS Blood DHFRL1 0.07 0.04 lasso 9 0.04 4.1e-14 7.2 6.9 4.6e-12 0.54 1.00 0.00 TRUE
4 The Cancer Genome Atlas Breast Invasive Carcinoma DHFRL1 0.07 0.05 lasso 1 0.05 3.4e-11 5.8 -5.8 5.2e-09 -0.43 0.12 0.88 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma STX19 0.04 0.02 lasso 1 0.01 5.5e-04 6.5 6.5 9.5e-11 0.64 0.00 0.94 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme DHFRL1 0.20 0.12 lasso 8 0.11 3.7e-04 5.8 -5.9 3.4e-09 -0.44 0.01 0.15 FALSE
7 The Cancer Genome Atlas Glioblastoma Multiforme STX19 0.52 -0.01 enet 15 0.17 5.6e-06 6.5 5.4 5.8e-08 0.30 0.00 0.18 FALSE
8 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DHFRL1 0.07 0.05 enet 17 0.05 2.5e-06 5.8 -6.5 1.0e-10 -0.54 0.04 0.93 FALSE
9 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DHFRL1 0.13 0.07 lasso 2 0.07 5.7e-08 5.8 -5.8 5.2e-09 -0.43 0.12 0.88 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma STX19 0.35 0.11 enet 12 0.20 2.4e-22 6.5 6.4 2.1e-10 0.49 0.00 1.00 FALSE
11 The Cancer Genome Atlas Brain Lower Grade Glioma DHFRL1 0.10 0.06 lasso 2 0.05 5.2e-06 5.8 -5.8 5.2e-09 -0.43 0.12 0.88 FALSE
12 The Cancer Genome Atlas Brain Lower Grade Glioma STX19 0.51 0.13 enet 19 0.34 3.9e-40 6.5 5.7 1.5e-08 0.40 0.00 1.00 FALSE
13 The Cancer Genome Atlas Liver Hepatocellular Carcinoma STX19 0.15 0.08 lasso 1 0.05 1.8e-03 6.5 6.5 9.5e-11 0.64 0.00 0.90 FALSE
14 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma STX19 0.28 -0.01 enet 15 0.08 6.4e-04 6.5 5.9 3.6e-09 0.44 0.00 0.33 FALSE
15 The Cancer Genome Atlas Thyroid Carcinoma ARL13B 0.03 0.00 blup 39 0.00 2.1e-01 -6.4 6.5 6.5e-11 0.66 0.01 0.67 TRUE
16 The Cancer Genome Atlas Thyroid Carcinoma STX19 0.24 0.03 enet 10 0.09 2.4e-09 6.5 5.4 8.1e-08 0.36 0.00 0.74 FALSE