TWAS hub - ARL13B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Testis	0.123	0.060	0.0052	0.000	NA	-0.006	NA	0.001	0.31	NA	0.97	NA	0.30
2	TCGA	Thyroid Carcinoma	0.030	0.021	0.0081	-0.001	0.002	-0.002	NA	-0.002	0.48	0.21	0.53	NA	0.51

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Illnesses of siblings: Diabetes	7.1	8.7	16.0	-1.2	4.0
BMI	6.2	36.2	72.2	0.2	8.5
Arm fat percentage (right)	5.6	21.9	43.8	-0.1	6.6
Arm fat mass (right)	5.5	22.4	44.8	0.4	6.7
Arm fat percentage (left)	5.3	21.3	42.7	-0.1	6.5
Medication: Simvastatin	5.2	7.7	15.4	-0.0	3.9
Reason for reducing amount of alcohol drunk: Health precaution	5.2	6.1	12.0	-0.4	-3.5
Arm fat mass (left)	5.1	21.0	41.6	0.5	6.5
Whole body fat mass	5.0	21.0	41.5	0.8	6.4
Body mass index (BMI)	4.9	20.9	41.6	0.5	6.5
Number of self-reported non-cancer illnesses	4.9	8.4	11.8	-2.2	3.4
Body fat percentage	4.8	18.8	37.2	0.7	6.1
Leg fat mass (left)	4.8	18.6	36.4	1.0	6.0
Leg fat mass (right)	4.7	18.1	35.4	0.9	6.0
Ever used hormone-replacement therapy (HRT)	4.6	5.8	8.7	-3.0	1.7
Trunk fat percentage	4.3	17.3	34.0	0.8	5.8
Trunk fat mass	4.3	18.6	36.4	1.0	6.0
Waist circumference	4.3	15.9	31.6	0.3	5.6
Allergy	4.2	9.7	15.0	2.1	-3.9
Asthma	4.2	8.4	14.9	-1.4	3.9
Leg fat percentage (left)	4.2	15.3	30.2	0.7	5.5
Leg fat percentage (right)	4.1	14.8	29.2	0.6	5.4
Number of treatments/medications taken	4.0	7.2	10.8	-1.9	3.3
Diabetes (mother)	4.0	5.1	5.3	-2.3	2.2
Medication: Metformin	3.8	5.3	10.3	0.6	3.2
Neck or shoulder pain in last month	3.6	5.1	10.0	-0.4	-3.2
Asthma (self-reported)	3.6	7.2	12.9	-1.2	3.6
Alzheimer’s Disease (in father)	3.5	3.8	5.0	2.2	-1.6
Weight	3.4	16.8	32.1	1.2	5.7
Smoking status: Previous	3.4	5.1	10.2	-0.1	3.2
Respiratory disease	3.3	7.3	14.4	-0.5	3.8
Pain all over the body in last month	3.2	3.4	5.0	-1.4	2.2
Maternal smoking around birth	3.1	4.5	8.2	-0.8	2.9
Qualifications: College or University degree	3.1	9.8	18.9	0.8	-4.3
Past tobacco smoking	3.0	5.5	10.6	-0.6	-3.2
Hip circumference	2.9	12.4	24.7	0.4	5.0
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	2.9	3.4	4.2	-2.0	1.6
Supplements: Calcium	2.9	3.2	5.5	-1.0	-2.4
Breastfed as a baby	2.8	3.5	6.4	-0.7	-2.5
Friendships satisfaction	2.7	3.4	6.6	0.3	-2.6
Intelligence (Savage-Jansen 2018)	2.6	7.9	15.0	0.9	-3.9
Frequency of tiredness / lethargy in last 2 weeks	2.6	4.1	5.3	-2.3	-1.7
Diabetes diagnosed by doctor	2.6	4.3	8.5	0.2	2.9
Fractured/broken bones in last 5 years	2.5	3.2	5.2	-2.3	1.1
Schizophrenia vs Biploar Disorder	2.4	3.1	6.3	0.0	-2.5
Medication: Cholesterol lowering	2.4	3.7	7.0	-0.7	2.6
Financial situation satisfaction	2.4	3.0	5.0	-1.0	2.2
Age at First Birth	2.3	3.3	6.7	0.1	-2.6
Back pain experienced in last month	2.3	3.3	5.8	0.9	-2.4
Average weekly spirits intake	2.2	2.8	5.0	-0.7	2.2
Frequency of unenthusiasm / disinterest in last 2 weeks	2.2	2.9	3.2	-1.6	-1.8
Hayfever, allergic rhinitis or eczema	2.2	4.7	5.8	-1.9	2.4
Medication: Lansoprazole	2.2	2.6	4.9	-2.2	0.4
Qualifications: O levels/GCSEs or equivalent	2.2	3.5	7.0	-0.2	-2.6
Deep venous thrombosis (DVT) (self-reported)	2.2	2.8	5.5	-2.3	0.3
Medication: Atenolol	2.1	2.6	3.1	1.4	1.8
Emphysema/chronic bronchitis	2.1	2.3	4.1	-0.7	2.0
Alzheimer’s Disease (including proxy)	2.0	2.8	3.7	1.9	-1.4
Type 2 Diabetes (T2D) (2018)	2.0	3.7	7.3	-0.4	2.7
Diabetes (self-reported)	2.0	3.1	5.8	0.6	2.4
High blood pressure (siblings)	2.0	2.9	4.0	-2.0	1.3
Fasting Glucose	1.9	2.3	4.5	-0.4	2.1
Lung FEV1/FVC ratio	1.9	9.8	18.8	-0.9	4.3
Diabetes (father)	1.9	2.3	3.1	1.8	1.2
Qualifications: None of the above	1.9	4.0	7.9	-0.3	2.8
Blood clot in the leg (DVT)	1.9	2.5	5.0	-2.2	0.1
Medication for cholesterol, blood pressure or diabetes	1.9	3.2	4.9	1.2	-2.2
High cholesterol (Self-reported)	1.9	3.4	5.7	-1.0	2.4
HbA1C	1.8	2.0	2.3	1.3	1.5
Leg fat-free mass (left)	1.8	9.6	18.9	0.5	4.3
Leg predicted mass (left)	1.8	9.3	18.3	0.6	4.3
Forced vital capacity (FVC)	1.8	6.8	11.2	1.6	-3.3
Fluid intelligence score	1.8	3.6	4.1	1.8	-2.0
Qualifications: A levels/AS levels or equivalent	1.8	4.0	7.7	0.5	-2.8
Leg pain on walking	1.8	2.3	2.7	-1.6	1.4
Leg fat-free mass (right)	1.8	9.4	18.6	0.4	4.3
Illnesses of father: High blood pressure	1.8	2.2	2.9	-1.3	1.7
Verbal and Numeric Reasoning (VNR)	1.7	4.0	6.4	1.3	-2.5
Townsend deprivation index at recruitment	1.7	2.4	3.4	-1.2	1.9
Health satisfaction	1.7	2.2	2.4	-1.5	1.5
Had major operations	1.7	2.0	4.0	-2.0	0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	1.7	2.0	4.0	-2.0	-0.2
Leg predicted mass (right)	1.7	8.9	17.8	0.3	4.2
Ever smoked	1.7	3.0	4.6	1.2	2.2
Cholesterol lowering medication	1.7	2.5	4.1	-0.9	2.0
Type 2 Diabetes (T2D) (2012)	1.6	1.8	3.6	0.0	1.9
Stomach or abdominal pain in last month	1.6	2.0	2.6	-1.2	-1.6
Prospective memory result	1.6	2.0	3.8	0.4	1.9
Length of working week for main job	1.6	1.7	2.4	-1.5	-1.1
Medication: Ventolin 100micrograms inhaler	1.6	2.0	3.2	0.9	1.8
Basal metabolic rate	1.6	9.1	17.2	1.0	4.2
Taking other prescription medications	1.5	2.3	2.4	-1.5	1.5
Hair/balding pattern: Pattern 2	1.5	1.9	2.9	1.7	-0.9
Heart attack	1.5	1.9	2.3	1.5	1.2
Pulse rate, automated reading	1.5	5.0	9.9	-0.1	3.1
Medication for cholesterol	1.5	2.2	4.4	0.1	-2.1
Commuting to job workplace: Public transport	1.5	1.8	3.3	1.8	0.5
Arm predicted mass (left)	1.5	7.4	12.8	1.4	3.6
Ever had hysterectomy (womb removed)	1.4	1.5	2.2	-1.5	0.9
Impedance of leg (right)	1.4	6.9	13.1	0.9	-3.6
Frequency of tenseness / restlessness in last 2 weeks	1.4	2.1	3.7	-1.9	-0.7
Illnesses of siblings	1.4	1.9	2.4	1.6	-1.2
Headache pain in last month	1.4	2.4	3.3	-1.8	-1.2
Forced vital capacity (FVC), Best measure	1.4	5.3	9.3	1.1	-3.1
Hearing aid user	1.4	1.5	2.0	1.4	-1.1
Pain type(s) experienced in last month: Hip pain	1.4	1.8	3.6	-1.9	0.2
Pain experienced in last month	1.4	2.4	3.3	1.8	1.2
Primary Biliary Cirrhosis	1.3	1.9	2.2	-1.5	1.3
Hearing difficulty/problems: Yes	1.3	2.0	3.9	2.0	-0.3
Eye problems/disorders: Diabetes related eye disease	1.3	1.5	2.7	0.5	1.6
Bilateral oophorectomy (both ovaries removed)	1.3	1.5	2.4	0.7	1.6
Impedance of leg (left)	1.3	6.2	11.8	0.7	-3.4
Hayfever/allergic rhinitis (self-reported)	1.3	1.8	3.4	-0.3	1.8
Mouth/teeth dental problems: Bleeding gums	1.3	1.7	3.4	1.9	0.1
Medication: Blood pressure	1.3	2.3	3.7	-1.0	1.9
Arm predicted mass (right)	1.3	6.9	11.2	1.6	3.3
Mood swings	1.3	2.4	2.6	-1.6	1.5
Medication: Lisinopril	1.3	1.7	1.9	-1.4	1.2
Arm fat-free mass (left)	1.3	6.3	11.2	1.2	3.3
Risk taking	1.3	1.9	3.6	1.9	0.5
Body Mass Index (BMI) (2010)	1.2	1.7	3.3	0.2	1.8
Coronary Artery Disease (CAD)	1.2	1.5	1.7	-1.1	-1.3
Smoking Status	1.2	2.9	5.8	-0.1	2.4
Forced expiratory volume in 1-second (FEV1)	1.2	4.1	6.7	1.3	-2.6
Loud music exposure frequency	1.2	1.3	2.3	0.5	1.5
Arm fat-free mass (right)	1.2	6.0	8.9	1.8	3.0
Medication: Seretide 50 evohaler	1.2	1.4	2.8	0.3	1.7
Qualifications: NVQ or HND or HNC or equivalent	1.2	1.4	2.2	0.8	1.5
Medication: Aspirin	1.2	1.6	3.1	-0.1	1.8
Heart attack/myocardial infarction (self-reported)	1.2	1.6	2.0	1.4	1.1
Ulcerative Colitis (UC)	1.1	2.1	3.6	-1.9	0.8
Alcohol usually taken with meals	1.1	1.8	2.0	-1.4	-1.3
Pulse rate	1.1	1.8	3.3	0.6	1.8
Serious illness, injury or assault of a close relative in last 2 years	1.1	1.2	2.1	-0.6	-1.4
Wheeze or whistling in the chest in last year	1.1	1.9	3.9	0.0	2.0
Whole body fat-free mass	1.1	6.4	11.5	1.1	3.4
Loneliness, isolation	1.1	1.5	1.8	1.0	1.4
Whole body water mass	1.1	6.3	11.4	1.1	3.4
Bipolar Disorder (2018)	1.0	1.6	3.1	0.1	1.8
Allergy or Eczema	1.0	2.5	3.2	-1.8	1.4
Cardiovascular Disease	1.0	3.4	5.9	-0.9	2.4
Medication for hormone replacement therapy	1.0	1.1	1.2	-1.1	1.1
Pulse wave peak to peak time	1.0	1.2	2.0	1.4	-0.6
Family relationship satisfaction	1.0	1.2	2.3	0.3	1.5
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	1.2	-1.1	1.1
Osteoporosis (self-reported)	1.0	1.2	2.4	-1.6	-0.2
Miserableness	1.0	1.6	3.3	0.2	-1.8
Ever taken oral contraceptive pill	1.0	1.1	2.0	0.4	1.4
Mother’s age at death	1.0	1.2	2.3	-0.4	-1.5
Diastolic blood pressure, automated reading	1.0	3.1	4.1	2.0	1.5
Myopia	1.0	1.4	2.1	1.5	-0.9
Frequency of depressed mood in last 2 weeks	0.9	1.3	1.5	-1.0	-1.2
Systolic blood pressure, automated reading	0.9	2.6	4.7	2.2	0.7
Heel bone mineral density (BMD) T-score, automated (left)	0.9	2.0	3.1	1.8	0.9
Father’s age at death	0.9	1.2	2.0	0.6	-1.4
Worrier / anxious feelings	0.9	1.7	2.7	-0.9	-1.6
Pulse wave Arterial Stiffness index	0.9	1.1	1.9	-1.4	0.5
Mouth/teeth dental problems: Loose teeth	0.9	1.1	2.1	-0.1	1.5
Eye problems/disorders: Cataract	0.9	1.0	2.0	-1.4	0.3
Commuting to job workplace: Cycle	0.9	1.1	1.9	-1.4	0.5
HDL Cholesterol	0.8	1.4	2.3	-0.7	1.5
Hand grip strength (left)	0.8	2.2	2.4	1.4	-1.5
Angina	0.8	1.1	1.7	-1.3	-0.7
Severe depression (siblings)	0.8	0.8	1.7	1.3	-0.1
Supplements: Glucosamine	0.8	1.0	1.7	-1.3	-0.6
Nervous feelings	0.8	1.5	3.1	-1.8	-0.1
Alcohol intake versus 10 years previously	0.8	1.2	2.3	-0.2	1.5
Number of live births	0.8	1.1	1.7	-1.3	0.7
Peak expiratory flow (PEF)	0.8	2.0	3.1	1.7	-0.9
Ever highly irritable/argumentative for 2 days	0.8	0.9	0.9	1.0	0.9
Birth weight	0.8	1.7	2.2	-1.1	-1.5
Age at first live birth	0.8	1.4	2.2	0.7	-1.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.8	0.9	1.6	-0.5	-1.2
Suffer from ‘nerves’	0.8	1.3	1.8	-1.3	0.9
Supplements: Vitamin C	0.8	0.9	1.8	0.1	-1.3
Illnesses of father: None of the above (group 1)	0.8	1.0	1.2	1.1	-1.0
Medication: Omeprazole (e.g. Zanprol)	0.8	1.0	1.6	-1.3	0.7
Impedance of whole body	0.8	4.0	8.0	-0.3	-2.8
Prostate Cancer	0.7	1.0	1.9	0.2	-1.4
Lung FVC	0.7	3.8	7.3	0.5	-2.7
Fed-up feelings	0.7	1.2	1.3	-1.1	1.1
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	1.3	-0.7	-1.1
Trunk fat-free mass	0.7	4.1	6.6	1.3	2.6
Trunk predicted mass	0.7	3.8	6.3	1.2	2.5
Angina (self-reported)	0.7	0.9	1.5	-1.2	-0.5
Commuting to job workplace: Car/motor vehicle	0.7	0.8	1.1	-1.1	-0.7
Forced expiratory volume in 1-second (FEV1), predicted	0.7	1.5	2.6	1.6	-0.6
Qualifications: nursing, teaching	0.7	1.1	1.9	-0.5	-1.4
Mouth/teeth dental problems: Mouth ulcers	0.7	1.2	1.3	-1.1	-1.0
Medication: Aspirin	0.7	0.9	1.8	-0.0	1.4
Number of operations (self-reported)	0.7	1.1	1.8	-1.4	0.6
Age started oral contraceptive pill	0.7	0.9	1.4	-0.7	-1.2
Neuroticism (Nagel 2018)	0.6	1.3	1.6	-1.0	1.3
Irritable Bowel Disease (IBD)	0.6	1.5	1.6	-1.2	1.3
Systolic Blood Pressure	0.6	2.9	5.8	2.4	-0.1
Hand grip strength (right)	0.6	1.8	3.3	0.4	-1.8
Medication: Levothyroxine sodium	0.6	1.0	1.7	-1.3	-0.6
Happiness	0.6	0.7	0.9	-0.6	1.0
Illnesses of mother	0.6	0.7	0.8	0.8	-0.9
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	1.8	3.1	0.8	-1.8
Impedance of arm (left)	0.6	2.6	4.5	-0.9	-2.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.6	1.0	1.5	-1.2	0.7
Medication: Paracetamol	0.6	0.9	1.9	-1.4	-0.1
Shortness of breath walking on level ground	0.6	0.7	0.8	-0.9	0.8
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.6	1.2	2.4	0.1	-1.6
Medication: Atorvastatin	0.6	0.8	0.8	-0.9	0.9
Average weekly beer plus cider intake	0.6	0.9	1.7	-0.4	1.3
Qualifications: CSEs or equivalent	0.5	0.7	1.4	0.1	-1.2
Multivitamins +/- minerals	0.5	0.6	1.2	1.1	-0.2
High blood pressure (mother)	0.5	0.7	1.2	-0.4	1.1
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.1	2.0	1.4	0.4
Birth weight of first child	0.5	0.9	0.9	-1.0	-0.9
Number of full brothers	0.5	0.6	1.2	-0.0	-1.1
Medication: Omeprazole	0.5	0.6	0.8	-0.7	0.9
Alcohol intake frequency.	0.5	1.1	2.1	0.3	1.5
Number of full sisters	0.5	0.6	1.2	-0.2	-1.1
Overall health rating	0.5	1.2	2.1	-1.4	0.5
Handedness (chirality/laterality): Left-handed	0.5	0.6	1.2	1.1	0.3
Breast cancer (self-reported)	0.5	0.6	1.0	1.0	0.3
Guilty feelings	0.5	0.8	1.3	-1.1	0.6
Medication: Blood pressure	0.5	1.0	1.8	0.3	1.3
Medication: Paracetamol	0.5	0.7	1.2	-1.1	-0.5
Irritability	0.5	0.8	1.7	0.2	1.3
Alcohol drinker status: Previous	0.5	0.5	0.6	-0.7	0.8
Bipolar Disorder or Schizophrenia	0.4	1.0	1.3	1.1	0.9
Depression (Nagel 2018)	0.4	0.6	1.0	-1.0	-0.5
Schizophrenia (2018)	0.4	0.9	1.7	1.3	-0.3
Alzheimer’s Disease (in mother)	0.4	0.5	0.9	1.0	0.0
Reaction Time	0.4	0.7	0.8	-0.9	0.7
Neuroticism (2016)	0.4	0.6	1.2	-1.1	0.1
Rheumatoid Arthritis	0.4	0.6	0.8	-0.9	0.7
Neuroticism	0.4	1.0	1.1	-1.0	1.0
Relative age voice broke	0.4	0.6	1.1	1.0	0.3
Serious illness, injury or assault to yourself	0.4	0.5	0.9	0.9	-0.4
Impedance of arm (right)	0.4	2.0	3.0	-1.1	-1.7
Falls in the last year	0.4	0.5	0.8	0.4	0.9
Hair/balding pattern: Pattern 4	0.4	1.1	1.3	-0.9	1.1
Pulse wave reflection index	0.4	0.5	0.8	-0.9	0.5
Medication for pain relief, constipation, heartburn	0.4	0.7	0.7	0.8	-0.8
Migraine (self-reported)	0.4	0.5	0.8	0.9	-0.5
Mean time to correctly identify matches	0.4	0.7	0.7	-0.8	0.8
Chest pain or discomfort	0.4	0.6	1.3	-1.1	-0.1
Wears glasses or contact lenses	0.4	0.5	0.6	0.6	-0.8
Unable to work because of sickness or disability	0.4	0.6	1.1	-1.0	0.3
Depressed Affect (Nagel 2018)	0.3	0.7	1.0	-0.6	1.0
Worry (Nagel 2018)	0.3	0.6	1.2	-1.1	0.2
Ovarian Cancer	0.3	0.5	0.5	0.7	-0.7
Schizophrenia (2014)	0.3	0.7	1.0	1.0	-0.7
Medication: Co-codamol	0.3	0.4	0.8	-0.9	-0.1
Tinnitus: Yes, but not now, but have in the past	0.3	0.3	0.4	0.6	0.6
Number of incorrect matches in round	0.3	0.5	1.1	-0.1	1.0
Standing height	0.3	2.5	3.8	1.9	-1.1
Worry too long after embarrassment	0.3	0.6	1.1	-0.2	-1.1
Medication: Allopurinol	0.3	0.4	0.7	0.3	0.9
Age at last live birth	0.3	0.5	0.8	0.9	0.3
Average weekly red wine intake	0.3	0.4	0.8	0.9	0.1
Long-standing illness, disability or infirmity	0.3	0.5	0.5	0.7	0.7
Ever had bowel cancer screening	0.3	0.4	0.7	0.1	-0.8
Mineral and other dietary supplements	0.3	0.4	0.5	0.7	0.5
Medication: Gliclazide	0.3	0.3	0.4	0.4	0.6
Supplements: Fish oil (including cod liver oil)	0.3	0.4	0.8	-0.9	0.0
Crohns Disease (2017)	0.2	0.5	0.7	0.4	0.9
Major Depression (MDD)	0.2	0.3	0.5	-0.2	0.7
Crohns Disease (2012)	0.2	0.3	0.5	0.0	-0.7
Mean Putamen Volume	0.2	0.2	0.4	-0.3	-0.6
Triglycerides	0.2	0.3	0.5	0.7	0.2
Ulcerative Colitis	0.2	0.3	0.7	0.0	0.8
Blood Eosinophil Count	0.2	1.4	2.4	0.7	1.5
Heel T-Score	0.2	1.3	1.9	0.8	1.4
Hypothyroidism (self reported)	0.2	0.4	0.5	-0.6	0.7
Chronotype (morning person)	0.2	0.4	0.7	0.8	0.1
Other serious medical condition/disability diagnosed by doctor	0.2	0.3	0.5	-0.7	-0.3
Vitamin and mineral supplements	0.2	0.3	0.4	-0.5	0.6
Supplements: Zinc	0.2	0.2	0.3	0.4	-0.6
Current tobacco smoking	0.2	0.3	0.5	0.1	0.7
Had other major operations	0.2	0.2	0.3	-0.4	0.6
Mouth/teeth dental problems	0.2	0.4	0.4	0.7	-0.5
Medication: Ramipril	0.2	0.2	0.2	0.5	-0.5
Neuroticism score	0.2	0.4	0.6	-0.8	0.4
Time employed in main current job	0.2	0.2	0.4	-0.2	-0.6
Hair/balding pattern: Pattern 3	0.2	0.2	0.3	-0.5	-0.4
Depression (self-reported)	0.2	0.3	0.3	-0.6	0.5
Glaucoma (self-reported)	0.2	0.2	0.4	0.2	0.6
Hypothyroidism/myxoedema (self-reported)	0.2	0.4	0.5	-0.5	0.7
Comparative body size at age 10	0.2	0.4	0.8	-0.9	-0.2
Eye problems/disorders: None of the above	0.2	0.2	0.3	-0.3	-0.5
Knee pain experienced in last month	0.2	0.2	0.3	-0.4	-0.6
Hypertension (Self-reported)	0.2	0.5	1.0	-0.2	1.0
Smoking status: Current	0.2	0.3	0.6	0.1	0.8
Medication: Bendroflumethiazide	0.2	0.3	0.5	-0.3	0.7
Ever depressed for a whole week	0.2	0.3	0.3	-0.5	0.6
Heart disease (siblings)	0.2	0.2	0.4	0.3	0.6
Breast Cancer	0.1	0.2	0.4	0.2	0.6
LDL Cholesterol	0.1	0.2	0.2	-0.3	-0.5
Lupus	0.1	0.1	0.2	-0.4	-0.3
Blood Platelet Count	0.1	1.3	2.6	-0.2	-1.6
Blood Red Count	0.1	0.6	1.2	1.1	0.2
Blood White Count	0.1	0.5	0.8	0.9	0.5
Height	0.1	1.6	2.7	1.6	-0.7
Sensitivity / hurt feelings	0.1	0.3	0.4	-0.2	0.7
Relative age of first facial hair	0.1	0.2	0.3	0.5	0.3
Age when periods started (menarche)	0.1	0.3	0.7	0.8	-0.1
High blood pressure	0.1	0.2	0.3	-0.3	0.5
Sitting height	0.1	0.9	1.3	0.7	1.1
Chronic bronchitis/emphysema (father)	0.1	0.1	0.2	0.4	0.1
Hearing difficulty/problems with background noise	0.1	0.2	0.4	0.6	0.2
Had menopause	0.1	0.1	0.2	0.2	-0.5
Ever unenthusiastic/disinterested for a whole week	0.1	0.1	0.1	-0.4	0.4
Financial difficulties in last 2 years	0.1	0.1	0.3	0.5	0.0
Noisy workplace	0.1	0.1	0.2	-0.5	-0.1
Mouth/teeth dental problems: Dentures	0.1	0.1	0.2	-0.3	0.4
Medication: Ibuprofen (e.g. Nurofen)	0.1	0.1	0.1	0.1	0.4
Lung cancer (father)	0.1	0.1	0.2	-0.4	-0.1
Exposure to tobacco smoke at home	0.1	0.2	0.3	0.5	0.2
Tense / ‘highly strung’	0.1	0.2	0.3	-0.5	0.3
Gout (self-reported)	0.1	0.1	0.3	-0.5	-0.1
Medication: Amlodipine	0.1	0.1	0.2	-0.5	0.0
Chronic bronchitis/emphysema (mother)	0.1	0.1	0.2	-0.5	-0.1
Number of children fathered	0.1	0.1	0.2	-0.4	-0.2
Heart disease (mother)	0.1	0.1	0.2	-0.4	-0.2
Comparative height size at age 10	0.1	0.4	0.7	0.3	-0.9
Illnesses of father: Heart disease	0.1	0.1	0.3	0.1	0.5
Osteoarthritis (self-reported)	0.1	0.1	0.2	-0.4	-0.3
Average weekly champagne plus white wine intake	0.1	0.1	0.2	-0.1	0.5
Tinnitus: Yes, now most or all of the time	0.1	0.1	0.1	0.3	0.1
Ever had prostate specific antigen (PSA) test	0.1	0.1	0.1	0.4	-0.1
Vascular/heart problems diagnosed by doctor	0.1	0.2	0.4	0.2	-0.6
Bipolar Disorder (2011)	0.0	0.0	0.0	0.0	0.0
Waist Hip Ratio (WHR)	0.0	0.2	0.4	-0.6	0.1
Hair Pigment	0.0	0.4	0.5	0.7	0.5
Tanning	0.0	0.6	0.9	-0.5	-1.0
Pack years adult smoking proportion	0.0	0.1	0.1	-0.1	0.4
Average weekly fortified wine intake	0.0	0.0	0.0	-0.1	-0.1
Exposure to tobacco smoke outside home	0.0	0.0	0.0	-0.1	-0.1
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.0	0.1	-0.1
Medication: Ibuprofen	0.0	0.0	0.0	0.1	-0.1
Ever had stillbirth, spontaneous miscarriage or termination	0.0	0.0	0.0	-0.2	-0.1
Commuting to job workplace: Walk	0.0	0.0	0.0	0.0	0.1
Eye problems/disorders: Glaucoma	0.0	0.1	0.1	-0.3	0.0
Alcohol drinker status: Never	0.0	0.0	0.0	-0.1	0.1
Basal cell carcinoma (self-reported)	0.0	0.0	0.0	0.2	0.2
Pack years of smoking	0.0	0.1	0.1	-0.3	0.2

Hub : Genes

ARL13B

Models

Trait associations