Best TWAS P=1.42e-09 · Best GWAS P=4.16e-14 conditioned to 0.0492
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cortex | FTSJ2 | 0.17 | 0.01 | enet | 16 | 0.06 | 1.1e-02 | 3.0 | 5.2 | 2.2e-07 | -0.61 | 0.05 | 0.58 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | AMZ1 | 0.09 | 0.05 | lasso | 6 | 0.04 | 2.4e-06 | -4.4 | 5.3 | 1.5e-07 | 0.05 | 0.26 | 0.70 | TRUE |
| 3 | The Cancer Genome Atlas | Prostate Adenocarcinoma | MAD1L1 | 0.09 | 0.01 | blup | 206 | 0.04 | 1.1e-04 | 5.7 | -6.0 | 1.4e-09 | 0.61 | 0.08 | 0.43 | TRUE |