Best TWAS P=1.75e-10 · Best GWAS P=7.21e-14 conditioned to 0.0109
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Breast Mammary Tissue (Female) | HOTAIRM1 | 0.26 | 0.02 | lasso | 4 | 0.04 | 1.8e-02 | 3.3 | 5.2 | 1.5e-07 | 0.51 | 0.10 | 0.49 | FALSE |
| 2 | GTEx | Stomach | HOTAIRM1 | 0.14 | 0.12 | lasso | 5 | 0.15 | 8.8e-08 | 5.8 | 6.2 | 5.7e-10 | 0.77 | 0.05 | 0.92 | FALSE |
| 3 | YFS | Blood | HOXA9 | 0.06 | 0.05 | lasso | 6 | 0.06 | 2.0e-19 | 7.5 | -6.1 | 1.1e-09 | -0.88 | 0.00 | 1.00 | FALSE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | HOXA10 | 0.02 | 0.01 | blup | 53 | 0.01 | 9.0e-03 | 6.7 | -5.2 | 2.2e-07 | -0.13 | 0.03 | 0.14 | TRUE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | HOXA9 | 0.04 | 0.04 | lasso | 2 | 0.04 | 1.4e-04 | 6.3 | -6.4 | 1.7e-10 | -0.91 | 0.01 | 0.98 | TRUE |