Best TWAS P=5.16e-08 · Best GWAS P=9.29e-06 conditioned to 0.565
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Heart Left Ventricle | RRN3 | 0.24 | 0.12 | lasso | 7 | 0.17 | 2.2e-09 | 4.3 | -5.5 | 5.2e-08 | -0.87 | 0.00 | 0.93 | TRUE |
| 2 | GTEx | Nerve Tibial | NTAN1 | 0.07 | 0.00 | enet | 14 | 0.00 | 1.7e-01 | 4.4 | 5.2 | 1.5e-07 | 0.46 | 0.00 | 0.06 | FALSE |
| 3 | NTR | Blood | PDXDC1 | 0.12 | 0.12 | enet | 26 | 0.15 | 1.3e-46 | -3.9 | 5.3 | 1.1e-07 | 0.74 | 0.02 | 0.73 | FALSE |