[Hub]/) : Traits : Arm fat mass (left) : ← →

chr17:4,137,919-6,068,117

Best TWAS P=1.03e-09 · Best GWAS P=2.64e-08 conditioned to 0.0016

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
2	GTEx	Brain Putamen basal ganglia	AC012146.7	0.30	0.03	enet	23	0.03	7.6e-02	4.1	-6.1	1.0e-09	-0.45	0.08	0.25	TRUE
5	GTEx	Esophagus Gastroesophageal Junction	GP1BA	0.35	0.16	lasso	11	0.18	5.9e-07	4.3	5.8	5.2e-09	0.56	0.18	0.71	FALSE
9	ROSMAP	Brain Pre-frontal Cortex	RPAIN	0.06	0.06	lasso	3	0.06	3.1e-08	5.5	-5.8	5.4e-09	-0.98	0.00	1.00	FALSE
11	The Cancer Genome Atlas	Glioblastoma Multiforme	RABEP1	0.23	0.13	blup	79	0.15	3.4e-05	4.6	-5.7	1.0e-08	-0.77	0.06	0.84	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	RABEP1	0.04	0.03	enet	5	0.03	1.5e-03	-4.4	-5.6	2.3e-08	-0.67	0.09	0.82	FALSE
3	GTEx	Esophagus Gastroesophageal Junction	DHX33	0.12	0.08	lasso	5	0.07	1.8e-03	5.5	-5.4	7.5e-08	-0.96	0.02	0.96	FALSE
12	The Cancer Genome Atlas	Prostate Adenocarcinoma	GP1BA	0.02	0.02	blup	49	0.02	9.3e-03	4.3	5.3	9.4e-08	0.33	0.01	0.61	FALSE
8	ROSMAP	Brain Pre-frontal Cortex	RABEP1	0.20	0.22	bslmm	546	0.20	7.4e-25	4.5	-5.3	1.0e-07	-0.75	0.44	0.54	FALSE
1	GTEx	Adrenal Gland	RABEP1	0.13	0.03	lasso	13	0.02	7.2e-02	-4.3	-5.3	1.1e-07	-0.80	0.03	0.83	FALSE
6	GTEx	Esophagus Muscularis	RABEP1	0.13	0.09	lasso	10	0.10	2.1e-06	5.5	-5.3	1.2e-07	-0.94	0.02	0.98	FALSE
4	GTEx	Esophagus Gastroesophageal Junction	RABEP1	0.19	-0.01	lasso	13	0.00	4.2e-01	4.5	-5.2	1.7e-07	-0.82	0.03	0.79	FALSE
13	The Cancer Genome Atlas	Soft Tissue Sarcoma	INCA1	0.06	0.00	enet	11	0.00	1.7e-01	4.3	5.2	1.8e-07	0.30	0.00	0.30	FALSE
10	The Cancer Genome Atlas	Glioblastoma Multiforme	NUP88	0.12	0.07	enet	12	0.09	1.2e-03	4.5	-5.1	2.8e-07	-0.78	0.02	0.67	FALSE
7	GTEx	Skin Sun Exposed Lower leg	AC012146.7	0.21	0.07	enet	17	0.18	1.3e-14	2.6	-5.1	2.9e-07	-0.45	0.95	0.01	FALSE