[Hub]/) : Traits : Arm fat mass (left) :

chr17:4,137,919-6,068,117

Best TWAS P=1.03e-09 · Best GWAS P=2.64e-08 conditioned to 0.0016

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland RABEP1 0.13 0.03 lasso 13 0.02 7.2e-02 -4.3 -5.3 1.1e-07 -0.80 0.03 0.83 FALSE
2 GTEx Brain Putamen basal ganglia AC012146.7 0.30 0.03 enet 23 0.03 7.6e-02 4.1 -6.1 1.0e-09 -0.45 0.08 0.25 TRUE
3 GTEx Esophagus Gastroesophageal Junction DHX33 0.12 0.08 lasso 5 0.07 1.8e-03 5.5 -5.4 7.5e-08 -0.96 0.02 0.96 FALSE
4 GTEx Esophagus Gastroesophageal Junction RABEP1 0.19 -0.01 lasso 13 0.00 4.2e-01 4.5 -5.2 1.7e-07 -0.82 0.03 0.79 FALSE
5 GTEx Esophagus Gastroesophageal Junction GP1BA 0.35 0.16 lasso 11 0.18 5.9e-07 4.3 5.8 5.2e-09 0.56 0.18 0.71 FALSE
6 GTEx Esophagus Muscularis RABEP1 0.13 0.09 lasso 10 0.10 2.1e-06 5.5 -5.3 1.2e-07 -0.94 0.02 0.98 FALSE
7 GTEx Skin Sun Exposed Lower leg AC012146.7 0.21 0.07 enet 17 0.18 1.3e-14 2.6 -5.1 2.9e-07 -0.45 0.95 0.01 FALSE
8 ROSMAP Brain Pre-frontal Cortex RABEP1 0.20 0.22 bslmm 546 0.20 7.4e-25 4.5 -5.3 1.0e-07 -0.75 0.44 0.54 FALSE
9 ROSMAP Brain Pre-frontal Cortex RPAIN 0.06 0.06 lasso 3 0.06 3.1e-08 5.5 -5.8 5.4e-09 -0.98 0.00 1.00 FALSE
10 The Cancer Genome Atlas Glioblastoma Multiforme NUP88 0.12 0.07 enet 12 0.09 1.2e-03 4.5 -5.1 2.8e-07 -0.78 0.02 0.67 FALSE
11 The Cancer Genome Atlas Glioblastoma Multiforme RABEP1 0.23 0.13 blup 79 0.15 3.4e-05 4.6 -5.7 1.0e-08 -0.77 0.06 0.84 FALSE
12 The Cancer Genome Atlas Prostate Adenocarcinoma GP1BA 0.02 0.02 blup 49 0.02 9.3e-03 4.3 5.3 9.4e-08 0.33 0.01 0.61 FALSE
13 The Cancer Genome Atlas Soft Tissue Sarcoma INCA1 0.06 0.00 enet 11 0.00 1.7e-01 4.3 5.2 1.8e-07 0.30 0.00 0.30 FALSE
14 The Cancer Genome Atlas Thyroid Carcinoma RABEP1 0.04 0.03 enet 5 0.03 1.5e-03 -4.4 -5.6 2.3e-08 -0.67 0.09 0.82 FALSE