Hub : Genes

NUP88

Models

# panel tissue h2 h2 se h2 P eQTL R2 BLUP R2 ENET R2 BSLMM R2 LASSO R2 eQTL P BLUP P ENET P BSLMM P LASSO P
1 CommonMind Brain Pre-frontal Cortex 0.1350 0.0300 5.3e-15 0.150 0.129 0.163 0.144 0.169 8.1e-18 2.2e-15 2.4e-19 4.2e-17 4.3e-20
2 GTEx Artery Tibial 0.1006 0.0356 5.3e-05 0.052 NA 0.023 NA 0.043 6.3e-05 NA 6.5e-03 NA 2.5e-04
3 GTEx Cells Transformed fibroblasts 0.0910 0.0330 3.9e-05 0.101 NA 0.098 NA 0.054 5.3e-08 NA 8.8e-08 NA 6.7e-05
4 GTEx Colon Transverse 0.1220 0.0500 1.3e-03 0.055 NA 0.015 NA 0.012 1.3e-03 NA 6.1e-02 NA 8.5e-02
5 GTEx Esophagus Mucosa 0.1770 0.0580 3.9e-05 0.111 NA 0.046 NA 0.073 7.0e-08 NA 5.0e-04 NA 1.3e-05
6 GTEx Muscle Skeletal 0.0528 0.0220 1.5e-03 0.009 NA 0.005 NA 0.004 4.0e-02 NA 1.0e-01 NA 1.1e-01
7 GTEx Nerve Tibial 0.0845 0.0340 5.3e-04 0.070 NA 0.059 NA 0.092 1.1e-05 NA 5.4e-05 NA 5.0e-07
8 GTEx Skin Not Sun Exposed Suprapubic 0.1970 0.0710 3.7e-04 0.042 NA 0.111 NA 0.131 2.3e-03 NA 1.1e-06 NA 1.2e-07
9 GTEx Skin Sun Exposed Lower leg 0.1940 0.0430 1.9e-12 0.128 NA 0.144 NA 0.124 9.1e-11 NA 5.8e-12 NA 2.0e-10
10 GTEx Testis 0.3100 0.0680 7.8e-11 0.419 NA 0.325 NA 0.404 4.2e-20 NA 4.8e-15 NA 3.0e-19
11 METSIM Adipose 0.0677 0.0257 2.3e-04 0.012 0.019 0.039 0.021 0.034 6.1e-03 6.8e-04 1.5e-06 3.8e-04 5.7e-06
12 NTR Blood 0.0463 0.0149 3.3e-07 0.030 0.027 0.029 0.026 0.030 5.8e-10 3.8e-09 1.1e-09 6.3e-09 4.8e-10
13 YFS Blood 0.2076 0.0301 0.0e+00 0.235 0.236 0.253 0.252 0.254 1.1e-75 5.8e-76 4.0e-82 8.2e-82 1.4e-82
14 TCGA Breast Invasive Carcinoma 0.0287 0.0140 3.1e-05 0.023 0.020 0.024 NA 0.025 1.2e-05 4.2e-05 6.9e-06 NA 6.7e-06
15 TCGA Colon Adenocarcinoma 0.1380 0.0680 2.9e-04 0.013 0.058 0.049 NA 0.029 5.3e-02 2.8e-04 8.4e-04 NA 8.1e-03
16 TCGA Glioblastoma Multiforme 0.1250 0.0760 3.7e-03 0.070 0.041 0.088 NA 0.048 3.7e-03 2.2e-02 1.2e-03 NA 1.4e-02
17 TCGA Kidney Renal Papillary Cell Carcinoma 0.1220 0.0640 4.4e-03 0.049 0.050 0.008 NA 0.041 8.6e-04 7.9e-04 1.1e-01 NA 2.1e-03
18 TCGA Brain Lower Grade Glioma 0.1108 0.0454 1.2e-10 0.111 0.091 0.085 NA 0.101 1.5e-12 1.5e-10 7.1e-10 NA 1.4e-11
19 TCGA Lung Squamous Cell Carcinoma 0.0235 0.0143 2.7e-03 0.031 0.015 0.019 NA 0.020 1.6e-04 6.5e-03 2.7e-03 NA 1.9e-03
20 TCGA Ovarian Serous Cystadenocarcinoma 0.0420 0.0300 9.9e-03 0.025 0.006 0.021 NA 0.010 8.2e-03 1.2e-01 1.4e-02 NA 6.7e-02
21 TCGA Stomach Adenocarcinoma 0.0830 0.0480 2.5e-04 0.010 0.037 0.061 NA 0.045 5.8e-02 1.0e-03 3.4e-05 NA 3.1e-04

Trait associations

Trait Avg chi2 ratio Avg chi2 Max chi2 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21
Bipolar Disorder (2018) 0.7 1.1 4.6 1.2 1.5 1.1 0.8 0.7 -1.0 1.0 1.7 0.2 0.7 0.1 1.0 1.1 1.1 -0.3 0.3 0.1 0.9 1.7 2.2 0.1
Bipolar Disorder or Schizophrenia 1.2 3.0 8.2 1.9 2.4 1.8 0.9 1.1 -1.8 2.1 1.9 1.3 1.8 1.0 1.2 2.1 2.0 0.8 1.3 0.9 1.7 2.9 2.2 1.8
Depressed Affect (Nagel 2018) 0.4 0.8 1.8 1.2 0.9 0.9 0.2 0.6 -0.5 1.2 0.1 0.8 0.7 1.4 0.4 1.3 1.0 0.7 1.0 1.3 1.0 0.2 0.4 0.8
Depression (Nagel 2018) 2.3 3.4 5.6 2.0 1.8 1.7 2.3 1.7 -1.1 2.0 1.7 2.3 1.9 2.4 1.3 2.1 2.0 0.2 2.2 0.7 1.9 1.9 2.3 1.9
Intelligence (Savage-Jansen 2018) 0.2 0.6 3.5 -0.2 -0.4 -0.4 -0.2 -0.8 0.3 -0.2 1.9 -0.9 -1.1 0.7 -1.0 -0.0 -0.6 -0.7 -1.4 0.8 -0.3 0.3 0.8 0.3
Neuroticism (Nagel 2018) 2.6 6.2 10.7 3.2 2.8 3.2 1.3 2.9 -1.6 3.1 1.8 2.5 2.4 1.9 2.5 3.3 2.5 1.4 2.8 2.2 3.1 2.5 1.7 2.0
Schizophrenia (2018) 1.1 2.2 5.5 1.5 1.9 1.4 0.5 0.9 -1.5 1.8 1.1 1.4 1.7 1.2 0.8 1.8 1.6 1.2 1.2 1.0 1.5 2.3 1.3 2.2
Schizophrenia vs Biploar Disorder 0.4 0.5 2.2 0.2 0.1 0.4 0.1 0.1 0.1 0.3 -1.2 1.0 0.3 -0.2 0.7 0.4 -0.1 0.7 1.0 0.6 0.4 -0.0 -1.5 1.4
Worry (Nagel 2018) 4.3 9.0 14.9 3.7 3.1 3.7 2.6 3.9 -1.5 3.8 1.9 3.1 3.0 1.8 3.2 3.8 3.6 0.8 3.5 2.3 3.6 3.1 2.1 2.0
Alzheimer’s Disease (in mother) 2.1 2.5 6.9 -1.2 -2.0 -1.5 -1.7 -2.0 2.6 -1.2 -1.2 -1.8 -1.9 -0.3 -1.5 -1.1 -1.1 -0.5 -1.6 0.7 -1.5 -2.3 -2.3 -0.5
Alzheimer’s Disease (in father) 1.2 1.3 8.2 -0.4 -0.7 -0.2 -0.8 0.2 2.9 -1.1 -0.2 -0.4 0.2 1.4 -1.3 -0.3 -1.7 -0.9 -1.2 -1.4 -0.3 -0.3 -0.4 2.1
Alzheimer’s Disease (including proxy) 5.2 7.6 22.7 -2.9 -3.0 -2.9 -2.6 -2.8 4.8 -2.5 -0.8 -3.2 -2.0 -0.4 -3.8 -2.3 -3.5 -2.4 -3.4 -2.0 -2.9 -2.9 -2.2 0.1
Crohns Disease (2017) 0.6 1.4 4.4 -1.4 -1.3 -1.6 -0.4 -1.2 1.5 -1.1 0.8 -0.4 -0.9 -0.7 -1.3 -1.3 -0.7 -0.8 -1.4 -1.5 -1.5 -1.0 -2.1 -0.2
Irritable Bowel Disease (IBD) 0.3 0.6 4.4 0.4 0.3 0.3 1.0 0.7 0.5 0.4 2.1 0.8 1.0 -0.3 0.2 0.5 0.4 0.7 -0.3 -0.7 0.4 0.3 -0.4 1.6
Ulcerative Colitis (UC) 1.3 2.4 5.9 1.7 1.4 1.6 2.2 1.7 -0.6 1.5 2.4 1.3 2.2 0.1 1.4 1.6 1.5 1.6 0.8 0.2 1.6 1.1 0.7 2.2
Major Depression (MDD) 0.4 0.5 2.3 0.7 -0.3 -0.2 1.0 0.0 -0.1 0.9 0.2 -0.4 -1.5 0.6 0.2 0.4 1.5 -1.1 -0.1 1.2 -0.1 -0.2 0.4 0.1
Reaction Time 1.6 3.1 8.4 -2.1 -2.1 -1.6 -0.5 -0.9 2.3 -2.1 -2.7 -0.5 -0.1 -0.5 -1.1 -1.7 -2.3 0.7 -1.9 -2.5 -1.4 -2.9 -2.3 0.5
Verbal and Numeric Reasoning (VNR) 0.3 0.8 3.0 -0.5 -0.8 -0.5 -0.2 -1.0 0.4 0.0 1.6 -1.3 -1.7 -0.5 -0.2 0.1 0.1 -1.7 -0.2 1.5 -0.4 0.2 0.7 -0.6
Breast Cancer 0.2 0.4 2.1 0.5 0.2 0.5 -0.2 1.0 -1.4 0.7 0.4 0.8 0.4 -0.8 0.6 0.3 0.9 0.4 0.1 0.0 0.5 1.0 0.8 -0.1
Ovarian Cancer 0.2 0.3 1.3 0.0 0.2 0.1 -0.1 0.2 -0.6 0.1 -0.9 -0.4 0.3 -0.4 -0.3 -0.2 0.6 -0.8 0.4 -0.7 -0.0 -0.3 0.5 -1.1
Prostate Cancer 0.3 0.5 1.0 -0.5 -0.7 -0.9 -0.9 -0.2 0.9 -0.6 0.6 -0.8 -0.3 0.4 -0.3 -0.9 -0.1 -0.9 -0.9 -0.9 -1.0 -0.0 -0.8 -0.5
Age at First Birth 0.5 0.7 3.0 -0.3 0.6 0.6 -0.8 1.0 0.1 -0.3 0.6 0.9 0.9 -1.7 0.5 0.2 -0.3 -0.8 0.7 -0.9 0.7 1.6 1.4 0.2
Bipolar Disorder (2011) 3.3 3.1 10.9 1.3 2.8 2.1 0.6 1.4 -1.0 1.1 3.0 0.9 2.5 0.7 1.1 1.9 0.3 0.2 1.1 -0.4 2.0 2.2 3.3 2.1
Body Mass Index (BMI) (2010) 5.3 7.2 11.2 -3.0 -3.3 -3.2 -1.6 -2.9 2.5 -2.9 -2.6 -3.0 -2.6 -1.9 -2.7 -3.0 -3.0 -0.2 -3.3 -1.3 -3.1 -3.3 -3.1 -1.3
Coronary Artery Disease (CAD) 0.7 0.8 2.5 0.8 0.5 0.7 0.1 0.6 -0.9 0.5 1.2 0.5 1.1 -1.6 1.5 0.6 0.5 1.6 0.7 0.8 0.4 0.9 0.5 0.4
Crohns Disease (2012) 0.4 0.7 3.2 0.1 1.0 0.4 0.1 0.7 -0.7 0.2 0.2 1.5 1.8 -0.3 0.1 0.3 -0.0 1.1 0.4 -1.5 0.3 1.0 -0.6 0.9
Mean Putamen Volume 0.1 0.1 0.4 -0.1 0.0 -0.2 -0.3 -0.4 -0.1 -0.2 -0.5 -0.6 -0.5 -0.2 -0.3 -0.2 -0.2 -0.5 -0.6 -0.2 -0.0 -0.2 -0.4 -0.4
Fasting Glucose 1.3 1.6 4.6 -1.4 -1.7 -1.4 -0.8 -1.7 1.3 -1.4 -1.7 -1.1 -2.1 0.4 -0.2 -0.9 -1.6 -1.3 -1.3 -0.0 -0.6 -1.8 0.1 -0.1
HbA1C 0.3 0.3 1.2 0.7 0.4 0.7 0.3 0.7 -0.1 0.5 0.1 0.4 -0.5 -0.0 0.6 0.5 -0.2 0.2 0.3 0.8 0.6 0.6 1.1 1.0
HDL Cholesterol 0.5 0.9 2.2 -0.7 -1.1 -0.9 -0.8 -0.9 1.5 -0.7 -0.2 -1.0 -0.9 -1.1 -0.5 -0.7 -0.2 -1.0 -0.9 -0.4 -0.9 -1.3 -1.4 -1.0
LDL Cholesterol 1.4 2.3 4.7 1.7 1.4 1.9 0.5 2.0 -1.2 1.7 0.7 1.1 1.6 0.9 1.6 1.9 0.9 1.6 1.7 1.2 2.0 0.9 1.6 2.2
Lupus 0.3 0.5 2.7 -0.1 -0.5 -0.2 -1.1 -0.4 0.6 -0.3 1.3 -0.6 -0.3 -1.6 -0.4 -0.2 -0.2 -1.0 0.3 -0.6 -0.2 -0.2 0.6 0.6
Neuroticism (2016) 1.3 1.8 3.2 1.8 1.0 1.2 1.6 1.8 -1.6 1.6 1.0 1.5 0.2 1.2 1.5 1.4 1.8 0.5 1.5 1.8 1.2 1.4 0.0 0.1
Primary Biliary Cirrhosis 0.5 0.7 2.2 1.0 0.9 0.9 0.7 0.7 -1.1 0.9 -0.2 1.5 0.9 0.1 0.5 0.9 0.9 1.4 0.6 0.5 0.8 0.5 0.6 0.3
Rheumatoid Arthritis 2.8 3.9 9.4 -2.0 -1.9 -2.2 -2.0 -2.1 1.3 -2.2 -1.0 -2.5 -1.6 -0.8 -3.1 -2.6 -2.1 -1.9 -2.3 -1.7 -2.2 -1.7 0.2 -2.1
Schizophrenia (2014) 3.7 8.2 16.4 2.8 3.5 3.1 1.8 2.7 -2.8 3.1 1.8 3.1 3.2 1.8 2.4 3.3 2.5 2.7 2.6 1.8 3.1 3.8 2.5 4.1
Triglycerides 0.2 0.3 2.2 -0.3 -0.6 -0.7 -0.2 -0.6 -0.2 -0.3 -0.1 -0.6 -1.5 -0.2 -0.5 -0.2 -0.3 -0.1 -0.6 0.8 -0.5 -0.9 -0.5 0.2
Type 2 Diabetes (T2D) (2012) 0.3 0.4 3.3 -0.2 -0.5 -0.2 0.1 -0.4 0.9 -0.2 1.6 -0.2 -0.2 -1.8 -0.0 -0.0 -0.3 -0.1 -0.5 0.0 -0.2 0.3 0.6 0.3
Ulcerative Colitis 0.9 1.3 4.8 1.1 1.1 1.2 1.0 1.4 -0.3 0.8 1.3 1.7 1.9 0.8 0.3 1.2 0.5 1.1 0.3 -0.4 1.2 0.8 1.3 2.2
Blood Eosinophil Count 0.4 3.1 8.9 -1.7 -1.4 -1.1 -2.0 -1.5 2.6 -2.0 1.1 -2.7 -0.2 -1.6 -1.4 -1.6 -1.8 -2.1 -1.0 -3.0 -1.0 -2.5 0.7 -0.1
Blood Platelet Count 1.3 15.0 25.9 -3.8 -4.9 -4.9 5.1 -4.8 4.7 -3.6 -4.7 -1.2 -3.6 2.6 -4.8 -3.2 -2.6 -2.4 -3.8 -4.0 -4.1 -4.3 -3.7 0.4
Blood Red Count 0.8 7.4 14.1 -2.9 -3.3 -3.0 -3.8 -2.6 2.8 -2.9 -0.1 -2.9 -3.2 -3.2 -2.2 -2.9 -2.8 -0.6 -2.8 0.0 -3.0 -3.4 -2.9 -2.0
Blood White Count 8.9 65.9 108.2 -9.0 -10.4 -9.6 -5.8 -8.5 10.3 -9.1 -5.8 -8.5 -8.3 -5.6 -9.2 -8.9 -8.2 -5.7 -8.9 -5.8 -9.1 -10.1 -5.5 -3.7
Heel T-Score 0.8 6.3 16.2 -2.9 -2.4 -1.8 -3.4 -1.8 3.9 -3.0 0.5 -2.1 -1.2 -4.0 -2.1 -2.6 -3.6 -2.6 -1.8 -3.1 -1.9 -2.1 0.2 -0.5
BMI 3.7 21.4 38.8 -5.1 -5.5 -5.6 -3.5 -4.8 5.4 -5.3 -4.2 -4.5 -4.4 -2.5 -5.2 -5.0 -5.3 -1.7 -6.2 -3.5 -5.4 -5.3 -3.7 -0.5
Height 0.1 1.9 4.4 -1.3 -1.6 -1.4 -1.5 -1.5 0.5 -1.7 -2.1 -0.2 -1.9 -2.0 -0.1 -1.6 -1.6 -0.4 -1.4 -0.7 -1.2 -1.3 -1.5 -1.1
Waist Hip Ratio (WHR) 0.3 1.2 4.9 1.3 0.5 1.1 -1.6 1.1 -0.1 1.0 1.5 -0.3 -0.5 -0.6 1.6 1.3 0.8 -0.1 1.0 2.2 1.2 0.5 0.1 1.0
Systolic Blood Pressure 0.5 2.3 4.8 1.4 1.5 1.7 -1.4 2.0 -0.5 1.1 1.6 1.6 0.4 -2.1 1.8 1.4 0.2 0.2 2.2 1.9 1.8 1.9 1.1 1.7
Smoking Status 0.7 1.8 6.5 -0.9 -0.7 -1.2 -1.5 -1.4 1.3 -1.1 -1.1 -2.5 -0.9 0.2 -1.5 -1.1 -0.9 -1.9 -2.5 -1.8 -1.0 -0.8 -0.0 -0.4
Allergy or Eczema 0.3 0.8 1.9 -0.8 -1.0 -1.1 -0.3 -0.8 1.2 -1.2 0.7 -0.5 -1.3 -0.8 -0.6 -1.0 -1.4 -0.4 -1.1 -0.9 -1.0 -0.6 -0.1 0.8
Cardiovascular Disease 0.4 1.5 4.0 1.1 1.0 1.4 -0.1 1.5 -0.7 1.2 1.4 0.9 0.3 -1.2 1.1 1.4 0.8 0.2 1.7 1.1 1.4 1.6 1.2 2.0
Hypothyroidism (self reported) 0.6 1.5 6.2 -1.1 -1.0 -1.2 0.2 -1.9 -0.1 -0.8 -0.6 -1.1 -2.0 -2.5 -0.7 -1.1 -0.4 -0.9 0.2 0.3 -1.1 -1.4 -1.4 -1.8
Respiratory disease 0.3 0.6 3.1 0.3 -0.4 -0.3 1.0 -0.3 0.2 0.6 1.2 0.3 -1.8 0.0 0.4 0.4 1.2 -1.0 0.5 1.5 -0.2 0.5 -0.8 0.2
Type 2 Diabetes (T2D) (2018) 1.9 3.6 6.9 -2.2 -2.3 -2.3 -1.7 -2.2 2.3 -2.0 -0.7 -2.1 -2.6 -1.6 -2.3 -1.9 -1.5 -1.3 -2.1 -0.3 -2.2 -2.1 -1.5 -0.9
Lung FEV1/FVC ratio 0.3 1.3 7.0 0.5 1.4 1.2 -0.2 1.2 -0.3 0.5 -0.3 0.2 2.6 0.4 0.5 0.6 -0.3 1.3 -0.6 -2.1 1.1 0.6 1.9 1.6
Lung FVC 0.4 2.0 8.6 -1.5 -0.5 -1.1 0.2 -1.0 0.5 -1.5 2.0 -1.5 0.7 -1.6 -1.8 -1.4 -1.6 -0.9 -1.5 -2.9 -1.1 -1.3 1.4 -1.3
Neuroticism 1.7 4.1 8.1 2.8 2.3 2.8 0.6 2.8 -0.9 2.6 0.5 1.9 1.9 0.6 2.1 2.8 1.9 1.1 2.0 2.2 2.8 2.2 0.8 1.4
Chronotype (morning person) 4.3 10.0 18.1 3.9 3.6 3.7 4.3 3.4 -2.7 3.5 2.4 3.2 2.7 1.4 3.7 3.6 3.4 1.6 3.8 2.4 3.7 3.2 1.8 2.2
Hair Pigment 0.1 3.0 8.0 2.4 2.0 1.4 1.6 1.7 -2.3 2.2 0.0 1.3 1.7 1.3 1.8 1.6 2.8 2.4 1.1 1.5 1.5 1.3 -0.5 1.0
Tanning 0.3 4.0 16.5 -1.9 -1.5 -2.1 -1.4 -2.1 1.4 -2.5 0.7 -3.0 -2.3 -0.3 -2.4 -2.2 -2.0 -4.1 -0.7 -1.6 -2.1 -1.2 0.0 -2.1
Hand grip strength (left) 2.7 7.1 12.6 -3.2 -2.9 -2.9 -2.3 -3.2 2.5 -3.2 -2.0 -2.5 -1.4 -1.3 -3.5 -3.1 -3.1 -2.5 -2.8 -3.5 -2.8 -2.1 -1.1 -2.4
Number of treatments/medications taken 0.1 0.2 0.8 0.3 0.0 0.3 0.9 0.5 -0.6 0.6 -0.7 -0.4 -0.3 0.1 0.4 0.6 0.9 -0.1 0.1 0.9 0.4 0.0 0.4 0.1
Average weekly spirits intake 0.6 0.8 3.7 -1.0 -0.4 -0.7 0.5 -0.4 0.4 -0.9 -1.9 -0.3 -0.4 -0.5 -0.5 -0.6 -1.6 0.2 -1.3 -1.2 -0.5 0.0 -1.0 1.2
Sensitivity / hurt feelings 1.1 1.9 6.6 1.7 1.5 1.6 0.4 1.2 -0.8 1.5 1.2 1.2 -0.1 -0.8 1.6 1.8 0.9 -0.5 2.6 2.3 1.8 1.3 0.9 0.3
Frequency of depressed mood in last 2 weeks 0.3 0.5 3.0 0.3 0.7 0.3 0.7 0.4 0.0 0.3 1.7 0.2 0.4 0.7 0.1 0.5 0.4 -1.0 0.5 -0.3 0.4 0.7 1.4 0.4
Hearing difficulty/problems: Yes 0.4 0.7 3.2 0.5 0.0 0.2 1.5 0.9 -0.3 0.3 0.2 1.5 0.3 0.2 0.9 0.4 0.2 1.7 0.0 0.5 0.2 0.5 -0.7 1.8
Relative age of first facial hair 0.4 0.8 4.0 0.4 0.6 0.9 0.4 1.7 -0.8 0.9 -0.1 0.1 1.6 0.3 0.5 0.9 0.5 0.9 0.1 -0.3 0.7 2.0 1.0 0.7
Other serious medical condition/disability diagnosed by doctor 0.4 0.5 3.1 0.2 0.1 0.1 0.6 0.3 1.1 0.0 0.6 -1.0 -0.2 -0.6 -0.3 0.2 -0.4 -1.8 -0.5 -0.7 0.1 0.6 0.9 1.4
Ever used hormone-replacement therapy (HRT) 6.9 8.7 17.6 3.1 3.3 3.4 2.7 3.7 -3.5 3.0 1.4 3.4 3.3 1.3 3.7 3.2 2.0 4.2 1.6 1.4 3.4 3.1 1.9 2.8
Ever had hysterectomy (womb removed) 0.6 0.7 2.2 0.9 0.9 0.3 1.4 0.0 -1.3 1.2 0.2 0.7 0.2 1.4 0.5 0.8 1.5 -0.1 0.8 1.0 0.6 0.9 0.2 -0.3
Systolic blood pressure, automated reading 0.5 1.5 4.6 0.8 1.0 1.3 -0.5 1.6 0.1 0.8 1.7 1.1 0.7 -1.5 1.1 1.2 -0.5 0.1 1.1 0.7 1.4 1.5 2.1 2.1
Eye problems/disorders: Diabetes related eye disease 0.3 0.3 1.8 0.2 0.5 0.4 -0.3 0.1 0.2 0.2 1.3 -0.2 0.3 -0.7 -0.8 0.4 0.3 -0.7 -0.3 -0.4 0.2 0.7 1.4 0.1
Angina 0.8 1.1 2.5 1.3 1.3 1.0 1.4 1.1 -1.2 1.4 0.1 0.7 0.6 0.2 0.9 1.1 1.6 0.6 0.7 0.8 1.0 1.3 -0.4 0.9
Medication for hormone replacement therapy 0.5 0.6 1.7 -0.7 -0.7 -0.9 0.6 -0.6 -0.7 -0.7 0.2 -1.0 -0.6 -0.5 -0.7 -1.0 -0.1 -0.0 -1.2 -1.0 -1.0 -0.6 0.1 -1.3
Vitamin and mineral supplements 0.2 0.3 1.7 -0.2 -0.5 -0.4 -1.1 -0.9 0.2 0.1 0.1 -0.1 -1.0 -0.6 -0.1 0.0 -0.2 0.3 -0.2 0.8 -0.2 0.3 -1.3 0.3
Supplements: Zinc 0.5 0.5 3.6 0.3 0.0 -0.5 1.6 -0.6 -0.3 0.1 1.4 -0.2 -0.4 1.9 -0.9 -0.2 0.3 0.3 -0.8 0.1 -0.4 -0.8 -0.3 0.2
Medication: Co-codamol 0.2 0.2 1.3 0.1 -0.3 -0.2 0.5 -0.3 0.7 -0.2 0.5 0.1 -0.7 0.3 -0.4 0.1 -0.6 -0.3 -0.5 0.2 -0.0 -0.6 0.0 1.1
Medication: Metformin 0.5 0.7 2.4 -0.8 -1.1 -0.7 -0.6 -1.0 1.6 -0.5 0.4 -1.0 -1.4 -0.7 -1.2 -0.3 -0.4 -1.4 -0.6 0.1 -0.6 -0.8 -0.1 0.2
Diabetes (father) 0.3 0.4 1.5 -0.6 -0.7 -0.7 -0.5 -1.2 0.8 -0.5 -0.0 -0.4 -0.9 -1.2 -0.6 -0.6 0.0 -0.6 -0.1 0.1 -0.8 -0.8 -0.8 0.0
Diabetes (mother) 0.8 1.0 4.1 -0.8 -1.2 -1.1 -0.6 -1.4 0.7 -0.8 -1.2 -0.8 -2.0 0.4 -0.7 -0.7 -0.3 -0.2 -1.3 0.9 -1.1 -0.6 -1.4 -1.1
Severe depression (siblings) 0.3 0.4 2.8 -0.2 -0.8 -0.7 0.6 -0.4 0.5 -0.1 0.5 -0.0 -1.7 -0.3 0.1 -0.2 0.4 0.1 -0.5 0.8 -0.7 -0.6 -0.5 0.6
Pack years adult smoking proportion 0.6 0.9 7.0 1.1 0.5 0.6 -1.4 0.1 -1.0 0.7 -0.9 0.3 -0.7 -0.5 0.2 0.6 0.7 0.2 1.1 2.6 0.7 0.3 -1.6 -0.4
Impedance of leg (right) 0.7 3.2 8.3 2.2 1.5 1.8 0.8 1.8 -2.0 2.1 1.6 1.3 0.8 0.1 2.5 1.8 2.4 1.2 2.9 2.9 1.9 1.2 0.2 0.7
Leg fat-free mass (left) 2.5 13.5 24.3 -4.2 -4.1 -4.1 -3.1 -4.3 4.3 -4.2 -3.1 -3.7 -3.6 -2.1 -4.1 -3.9 -4.2 -2.4 -4.9 -3.1 -4.0 -3.8 -2.2 -1.8
Trunk fat percentage 2.4 9.6 17.6 -3.5 -3.8 -3.7 -2.1 -3.7 3.7 -3.4 -2.2 -3.3 -3.5 -2.3 -3.0 -3.3 -3.5 -0.8 -3.7 -1.5 -3.5 -4.2 -2.4 -0.7
Hand grip strength (right) 2.6 7.2 11.0 -3.3 -3.2 -3.2 -1.8 -3.1 2.8 -3.2 -1.1 -2.6 -1.9 -1.5 -3.1 -3.1 -2.9 -2.2 -3.3 -3.1 -3.1 -2.1 -1.6 -2.0
Townsend deprivation index at recruitment 0.6 0.8 3.9 0.9 1.0 0.7 -0.5 0.8 -0.8 0.9 -2.0 -0.4 0.9 1.0 0.5 0.7 1.3 0.4 0.4 0.2 0.7 0.7 -0.9 -1.5
Current tobacco smoking 0.1 0.2 1.0 0.1 -0.1 -0.4 0.1 -0.8 0.5 0.1 0.4 -1.0 -0.5 0.6 -0.3 0.1 0.3 -0.8 -0.9 0.1 -0.2 0.1 -0.5 0.4
Average weekly fortified wine intake 0.4 0.5 2.4 -0.7 -0.7 -0.4 0.2 -0.7 0.5 -0.7 -1.4 -0.1 0.1 0.1 -0.5 -0.5 -0.5 0.7 -0.5 -0.2 -0.5 -0.6 -1.6 -0.9
Maternal smoking around birth 0.4 0.6 2.3 -0.1 -0.7 -1.1 -0.4 -0.9 -0.2 -0.3 -0.9 -0.1 0.1 1.2 -1.4 -0.5 0.1 1.0 -0.8 -0.0 -1.0 -1.1 -1.5 0.3
Fed-up feelings 0.2 0.3 3.0 0.2 0.7 0.4 -1.7 0.1 -0.0 -0.1 -0.4 -0.4 -0.0 -0.1 0.1 0.2 -0.2 0.2 -0.4 0.6 0.3 -0.7 -0.4 -0.5
Frequency of unenthusiasm / disinterest in last 2 weeks 1.8 2.4 4.6 1.9 1.9 1.7 1.7 1.6 -1.1 1.7 1.1 1.6 2.1 1.8 1.4 1.9 1.6 0.8 1.2 0.4 1.9 1.8 1.2 1.0
Relative age voice broke 0.2 0.4 1.7 -0.1 0.3 0.7 0.0 1.1 0.2 0.3 0.5 -0.5 0.8 -1.3 0.4 0.6 0.3 -0.2 0.8 -0.4 0.6 0.5 0.2 0.7
Taking other prescription medications 0.9 1.4 5.5 1.2 1.0 1.2 1.5 0.9 -1.5 1.5 -0.2 0.8 -0.4 -0.1 1.4 1.4 1.6 0.5 1.6 2.4 1.2 0.8 -0.3 0.3
Age when periods started (menarche) 2.9 7.1 13.3 3.1 3.5 3.6 1.2 3.3 -3.1 3.0 0.0 3.2 2.8 1.0 2.1 3.2 2.0 1.5 3.0 1.3 3.6 2.3 2.4 2.6
Bilateral oophorectomy (both ovaries removed) 0.2 0.2 1.7 0.4 -0.1 -0.1 0.7 -0.1 0.8 0.0 1.3 0.3 0.0 -0.4 0.1 0.1 0.3 -0.4 -0.0 -0.1 -0.0 0.4 0.4 0.4
Heel bone mineral density (BMD) T-score, automated (left) 1.0 2.3 5.6 -1.6 -1.3 -1.2 -2.3 -1.0 2.1 -2.0 -0.1 -1.5 -0.5 -0.7 -1.5 -1.6 -2.4 -0.7 -2.3 -1.8 -1.2 -1.2 -1.2 0.2
Tinnitus: Yes, but not now, but have in the past 1.2 1.3 3.7 -1.1 -1.6 -1.4 -0.8 -1.3 1.2 -1.1 -1.1 -0.8 -0.7 -0.2 -1.5 -1.2 -0.8 -0.1 -1.2 -1.2 -1.4 -1.9 -1.1 0.2
Qualifications: CSEs or equivalent 0.9 1.2 7.2 -0.1 -1.1 -0.9 -0.8 -1.2 1.5 -0.6 -1.1 -0.6 -1.4 -0.9 -1.2 -0.6 0.1 -0.1 -0.6 0.7 -0.8 -1.7 -2.7 -0.1
Serious illness, injury or assault to yourself 1.3 1.6 5.7 -1.0 -1.2 -1.5 -0.7 -1.4 1.1 -0.8 -2.0 -0.9 -0.8 0.5 -1.6 -1.1 -0.5 0.7 -1.7 -0.5 -1.4 -1.5 -2.4 0.1
High blood pressure 1.2 3.4 6.8 2.0 1.7 2.2 1.2 2.2 -1.5 2.3 0.8 1.5 0.8 -0.2 2.2 2.3 1.9 0.9 2.6 2.3 2.3 2.0 1.7 1.7
Hayfever, allergic rhinitis or eczema 0.1 0.2 1.1 -0.1 -0.3 -0.4 0.4 -0.3 0.4 -0.5 0.6 0.0 -0.8 -0.2 -0.2 -0.3 -0.5 -0.2 -0.3 -0.5 -0.4 -0.1 0.5 1.1
Multivitamins +/- minerals 0.4 0.5 3.0 0.3 0.5 0.6 1.7 0.8 0.3 0.1 0.4 0.6 1.2 1.3 0.0 0.1 0.2 -0.1 0.7 -0.9 0.3 -0.2 1.1 0.5
Stomach or abdominal pain in last month 1.6 2.0 3.4 1.8 1.2 1.7 0.6 1.8 -0.8 1.6 0.5 1.8 0.9 0.6 1.7 1.8 1.1 0.6 1.2 1.7 1.7 1.5 1.5 1.9
Supplements: Glucosamine 0.4 0.5 3.4 -0.1 -0.5 -0.2 1.0 0.8 -0.2 -0.5 -1.8 -0.0 0.4 -0.1 -0.3 -0.4 -1.0 1.2 -1.2 -1.0 -0.3 -0.4 -0.2 -0.0
Diverticular disease/diverticulitis (self-reported) 0.4 0.4 3.4 -0.2 -0.1 -0.1 -0.7 -0.4 -0.1 -0.2 -1.7 0.2 0.0 -1.8 -0.4 -0.3 0.0 -0.6 0.7 -0.8 0.1 0.0 -0.1 -0.7
Medication: Atenolol 3.7 4.6 10.3 2.3 2.1 2.2 1.9 1.8 -1.9 2.7 2.0 2.3 1.0 2.2 2.3 2.6 2.5 1.7 2.0 3.2 2.3 2.1 1.4 1.4
Medication: Levothyroxine sodium 0.9 1.6 5.7 -1.3 -1.2 -1.5 0.3 -2.0 0.2 -1.1 -0.9 -0.9 -2.2 -2.4 -0.9 -1.3 -0.5 -1.1 -0.5 -0.2 -1.6 -0.8 -1.3 -1.1
Sitting height 0.2 1.7 5.0 -1.3 -0.9 -1.0 -2.2 -1.5 1.3 -1.5 -1.0 -1.4 -1.0 -2.0 -0.7 -1.3 -1.7 -0.8 -1.4 -0.9 -1.0 -1.7 -0.7 -0.8
Chronic bronchitis/emphysema (father) 1.3 1.6 4.3 -1.5 -1.2 -1.2 0.8 -1.7 1.1 -1.2 -2.1 -1.7 -0.2 -0.2 -1.2 -1.2 -0.9 -0.1 -1.2 -1.8 -1.2 -1.9 -0.6 -1.1
High blood pressure (mother) 2.3 3.2 7.3 1.7 2.0 2.6 0.1 2.3 -1.1 1.5 2.0 2.4 1.2 0.0 2.7 2.1 0.4 2.0 1.9 1.7 2.4 1.2 1.3 1.4
Body mass index (BMI) 3.6 15.2 26.1 -4.5 -4.5 -4.7 -2.6 -4.5 4.5 -4.6 -2.7 -4.0 -3.8 -2.1 -4.5 -4.3 -4.6 -1.7 -5.1 -3.0 -4.6 -4.4 -2.9 -0.8
Impedance of leg (left) 0.5 2.4 6.4 2.0 1.5 1.6 0.8 1.7 -1.6 1.8 1.7 0.9 1.1 0.3 2.2 1.5 2.2 0.9 2.5 2.2 1.6 0.9 0.0 0.7
Leg predicted mass (left) 2.7 14.0 24.9 -4.3 -4.2 -4.2 -3.2 -4.4 4.3 -4.2 -3.1 -3.9 -3.6 -2.2 -4.2 -4.0 -4.3 -2.5 -5.0 -3.2 -4.1 -3.9 -2.3 -1.9
Trunk fat mass 3.4 14.7 23.0 -4.3 -4.6 -4.5 -2.9 -4.5 4.5 -4.3 -3.0 -4.0 -4.2 -2.7 -3.9 -4.1 -4.4 -1.5 -4.8 -2.3 -4.3 -4.8 -2.9 -1.2
Waist circumference 2.4 8.9 14.1 -3.2 -3.6 -3.4 -2.6 -3.3 3.6 -3.3 -1.8 -3.3 -3.7 -2.1 -3.0 -3.1 -3.4 -1.7 -3.8 -1.6 -3.3 -3.7 -1.9 -0.5
Number of incorrect matches in round 1.9 3.1 8.2 1.4 1.6 1.8 1.9 1.7 -1.1 1.3 2.6 2.9 1.4 0.7 2.2 1.6 0.9 0.1 2.6 0.3 1.7 2.2 2.1 1.9
Past tobacco smoking 1.4 2.7 6.7 1.5 0.7 1.2 2.2 1.6 -1.1 1.9 1.7 2.6 1.4 1.3 1.6 1.7 2.0 2.1 1.7 2.3 1.1 1.3 -0.5 0.9
Alcohol usually taken with meals 0.4 0.7 2.0 -1.0 -1.2 -0.8 -0.7 -0.5 1.2 -0.8 -0.3 0.5 -1.4 -1.1 -0.4 -0.7 -1.1 -0.5 0.2 0.8 -0.7 -0.6 -0.6 -0.1
Nervous feelings 7.8 14.5 22.5 4.4 4.3 4.5 3.7 4.4 -3.2 4.7 1.6 4.2 3.9 2.5 4.5 4.6 4.7 3.0 4.0 2.9 4.3 3.8 1.3 2.4
Frequency of tenseness / restlessness in last 2 weeks 3.5 5.4 8.8 3.0 2.4 2.4 2.5 2.6 -2.1 2.9 1.6 2.4 2.1 2.0 2.6 2.9 2.9 1.9 1.9 1.7 2.4 2.4 1.3 2.0
Hearing difficulty/problems with background noise 1.4 2.2 8.6 1.6 0.8 1.4 2.0 1.5 0.0 1.3 0.6 2.5 1.5 1.5 1.3 1.5 1.2 1.5 1.2 1.2 1.5 1.2 -0.5 2.9
Hair/balding pattern: Pattern 2 0.3 0.4 2.4 0.2 0.1 -0.1 -1.6 -0.2 0.1 0.1 0.1 -1.0 -0.4 -0.5 -0.2 0.0 0.1 -0.2 -0.2 1.0 0.0 -0.1 -1.3 -1.2
Had menopause 6.4 8.0 13.6 2.5 3.3 3.2 2.7 3.5 -3.6 2.9 2.1 3.2 3.3 0.5 3.2 3.0 2.5 2.3 2.6 0.7 3.1 3.7 3.2 1.9
Had other major operations 0.4 0.5 1.7 -0.4 -0.6 -0.7 0.2 -1.3 0.4 -0.4 0.4 -0.2 -1.3 -0.4 0.1 -0.3 0.2 -1.2 0.5 0.4 -0.7 -0.4 -1.3 -0.7
Forced vital capacity (FVC) 1.3 4.8 10.0 -2.4 -1.9 -2.0 -2.7 -2.6 2.2 -2.5 -0.5 -3.2 -1.4 -2.1 -2.2 -2.4 -2.6 -1.9 -2.5 -2.2 -2.0 -2.6 -0.6 -1.6
Heel bone mineral density (BMD) T-score, automated (right) 0.5 1.1 3.9 -0.9 -0.9 -0.8 -1.4 -0.2 1.6 -1.4 0.1 -1.0 -0.3 0.3 -1.1 -1.0 -1.6 -0.4 -2.0 -1.3 -0.8 -0.7 -1.3 0.8
Ever unenthusiastic/disinterested for a whole week 0.6 0.7 2.5 1.2 0.6 0.6 0.1 0.6 -0.6 1.4 -0.8 -0.1 0.1 0.9 0.7 1.1 1.6 0.8 -0.2 1.2 0.7 1.2 -0.4 0.3
Qualifications: None of the above 0.9 2.0 6.3 1.6 1.3 1.0 1.7 0.8 -2.5 1.4 -0.2 1.6 1.8 1.7 1.2 1.0 1.4 2.5 0.8 0.5 1.1 1.0 -0.3 1.3
Financial difficulties in last 2 years 4.2 5.6 9.1 -2.4 -2.5 -3.0 -1.8 -3.0 2.7 -2.5 -2.1 -2.6 -2.1 -0.5 -2.6 -2.7 -1.8 -2.2 -2.4 -2.3 -2.9 -2.6 -1.9 -1.9
Mouth/teeth dental problems 3.0 4.6 8.4 -2.6 -2.5 -2.0 -2.9 -1.6 2.2 -2.4 -1.8 -2.9 -2.3 -1.9 -2.2 -2.3 -2.8 -2.1 -2.1 -1.5 -1.9 -1.8 -0.8 -1.3
Heart attack 1.2 1.5 11.4 1.4 0.2 0.7 0.3 0.6 -0.8 1.4 -0.0 0.6 -1.5 0.5 1.9 1.1 2.0 0.7 0.8 3.4 0.6 0.4 -0.9 0.7
Allergy 0.1 0.3 1.3 -0.1 0.3 0.3 -1.0 0.3 -0.4 -0.1 -0.7 -0.4 1.1 0.6 -0.4 -0.0 -0.3 0.9 -0.2 0.1 0.3 -0.6 -0.3 -0.8
Pain all over the body in last month 0.4 0.4 1.9 0.6 0.4 0.4 1.4 0.4 -0.0 0.3 0.7 0.1 0.8 0.9 0.8 0.4 0.3 0.9 -0.1 -0.5 0.2 0.2 1.0 0.2
Diabetes (self-reported) 1.8 2.8 5.1 -2.1 -1.9 -1.9 -1.5 -2.0 2.2 -1.8 -0.2 -1.8 -2.3 -2.2 -1.9 -1.7 -1.3 -1.6 -1.9 -0.7 -1.9 -1.3 -0.5 -0.6
Hayfever/allergic rhinitis (self-reported) 0.3 0.3 3.1 0.2 0.5 0.0 0.6 0.2 -0.6 0.2 1.8 -0.0 -0.3 -0.6 0.4 0.1 0.3 -0.2 0.8 0.2 0.2 0.5 1.2 0.4
Medication: Ramipril 0.4 0.5 2.9 0.7 0.2 0.3 0.8 0.1 -0.7 0.9 -0.7 -0.0 -0.6 0.2 0.3 0.6 1.1 0.6 0.3 1.7 0.5 -0.1 -1.2 0.4
Medication: Simvastatin 1.1 1.6 3.6 1.0 1.3 1.4 0.4 0.6 -1.7 1.3 0.9 1.6 0.3 -0.7 1.5 1.4 0.9 1.1 1.2 1.7 1.5 1.9 1.0 1.7
Fluid intelligence score 0.6 1.2 4.6 -1.0 -1.1 -1.1 -0.4 -0.9 1.3 -0.4 1.2 -2.1 -2.1 -0.2 -0.6 -0.5 0.1 -2.1 -1.3 0.7 -1.0 -0.5 -0.0 -0.8
Illnesses of siblings 0.6 0.9 2.5 -0.9 -1.0 -0.9 -1.0 -1.0 1.6 -1.0 -0.9 -0.2 -0.1 -0.0 -1.4 -0.8 -1.2 -0.6 -1.2 -1.2 -0.8 -0.5 -1.3 0.2
Neuroticism score 1.4 2.9 6.1 2.4 2.1 2.4 -0.1 2.5 -0.3 2.2 0.9 1.1 1.5 -0.2 1.8 2.5 2.1 0.2 1.8 2.0 2.4 1.6 0.7 0.6
Weight 3.3 16.5 28.3 -4.6 -4.7 -4.7 -3.2 -4.7 4.6 -4.7 -3.2 -4.1 -4.2 -2.5 -4.3 -4.4 -4.7 -2.1 -5.3 -3.0 -4.6 -4.6 -2.9 -1.3
Impedance of arm (right) 2.1 9.7 18.5 3.8 3.0 3.5 2.6 3.2 -2.7 4.0 2.2 3.0 2.2 2.0 3.9 3.7 4.2 1.9 4.3 3.8 3.5 2.5 1.8 1.1
Arm fat percentage (right) 2.5 10.0 17.2 -3.6 -3.9 -3.8 -2.0 -3.7 4.1 -3.5 -2.2 -3.3 -3.2 -2.0 -3.4 -3.3 -3.5 -1.0 -4.0 -2.2 -3.6 -3.8 -2.4 -0.4
Trunk fat-free mass 2.4 14.0 24.1 -4.3 -4.0 -4.2 -3.4 -4.4 4.0 -4.5 -2.8 -3.8 -3.4 -2.3 -4.1 -4.1 -4.5 -2.8 -4.9 -3.4 -4.1 -3.5 -2.5 -2.1
Hip circumference 3.4 14.6 25.0 -4.4 -4.5 -4.6 -2.7 -4.5 4.5 -4.3 -2.7 -3.8 -3.9 -2.0 -4.5 -4.1 -4.5 -2.1 -5.0 -3.1 -4.4 -4.2 -2.3 -0.8
Time employed in main current job 0.5 0.5 2.1 -0.5 -0.0 -0.3 -1.4 -0.1 0.1 -0.8 -0.2 1.1 0.5 -0.1 -1.2 -0.6 -1.4 0.3 -0.5 -1.1 -0.3 0.2 0.1 1.2
Alcohol intake versus 10 years previously 3.9 5.9 14.6 -2.2 -3.2 -3.2 -1.4 -3.1 1.6 -2.1 -1.7 -2.7 -3.8 -0.8 -2.9 -2.6 -1.1 -2.5 -2.9 -1.0 -3.0 -2.2 -2.4 -1.9
Father’s age at death 0.1 0.2 1.2 0.5 0.3 0.3 0.5 0.4 -0.0 0.4 1.1 -0.1 0.4 0.1 0.5 0.5 0.6 0.6 -0.1 0.4 0.4 0.2 -0.1 0.5
Worrier / anxious feelings 0.9 1.7 3.5 1.3 1.4 1.5 0.6 1.7 0.1 1.2 1.8 1.2 1.1 -1.1 1.5 1.4 1.3 -1.1 1.9 0.2 1.4 1.5 1.6 0.4
Frequency of tiredness / lethargy in last 2 weeks 0.2 0.3 1.6 0.0 -0.6 -0.6 0.3 -0.6 -0.2 -0.2 0.3 -0.3 -1.3 0.4 -0.4 -0.2 0.2 0.1 -0.4 0.9 -0.5 -0.7 -0.7 -0.1
Falls in the last year 0.4 0.5 2.8 0.3 -0.3 -0.0 0.5 0.4 -0.1 0.4 -1.0 0.7 -0.7 0.7 0.6 0.2 0.5 1.7 -0.7 1.4 -0.2 -0.4 -1.2 0.1
Hair/balding pattern: Pattern 3 2.4 3.6 6.4 -2.5 -2.5 -2.3 -1.4 -2.5 2.1 -2.2 -0.5 -1.2 -2.2 -1.7 -1.2 -2.3 -1.8 -1.2 -1.5 -0.9 -2.5 -2.4 -1.5 -1.2
Number of live births 0.6 0.8 5.5 0.2 -0.1 -0.7 0.3 -0.9 -1.2 0.5 -0.9 0.1 -0.1 0.6 -0.6 -0.1 1.0 1.9 -0.3 1.2 -0.6 -0.2 -2.3 0.2
Forced expiratory volume in 1-second (FEV1) 1.5 5.0 9.9 -2.5 -2.0 -1.9 -2.8 -2.4 2.5 -2.6 -0.7 -3.1 -0.9 -2.4 -2.1 -2.4 -2.9 -1.4 -2.6 -2.7 -2.0 -2.8 -0.3 -1.2
Pulse rate 0.6 1.1 2.7 1.0 1.3 1.0 1.6 1.2 -0.1 1.1 1.2 1.2 1.3 1.4 0.4 1.0 1.3 -0.2 0.6 -0.7 1.0 0.8 0.9 1.1
Happiness 3.4 4.1 7.3 2.3 2.3 2.4 1.3 2.0 -1.9 2.4 1.6 2.1 1.8 0.7 2.7 2.5 2.2 1.1 2.0 1.0 2.4 2.4 1.7 1.9
Noisy workplace 0.6 0.8 3.7 -0.6 -0.8 -0.9 -0.7 -0.9 -0.1 -0.8 -1.9 -0.0 -0.3 0.3 -0.3 -1.0 -0.9 1.3 -0.8 -0.4 -0.9 -1.4 -1.1 0.3
Qualifications: A levels/AS levels or equivalent 0.5 1.1 4.0 -1.3 -1.1 -0.7 -2.0 -0.4 1.3 -1.0 -0.2 -1.3 -1.1 -0.3 -0.9 -1.0 -1.4 -0.5 -1.6 -0.5 -0.8 -1.0 0.4 -0.8
Serious illness, injury or assault of a close relative in last 2 years 1.5 1.8 7.2 -1.7 -1.2 -1.2 -1.6 -1.1 1.7 -2.0 -0.7 -1.1 -1.1 -0.2 -1.1 -1.5 -2.7 0.0 -1.1 -0.7 -1.2 -1.7 -1.0 -0.4
Mouth/teeth dental problems: Dentures 3.8 6.5 12.0 2.6 2.7 2.7 3.2 2.1 -2.5 2.8 1.6 3.5 2.5 1.7 3.0 2.9 2.4 3.3 2.3 2.2 2.7 1.6 1.3 2.5
Asthma 0.4 0.8 5.3 -0.1 -1.0 -0.7 -0.3 -0.7 0.9 0.1 0.3 -0.1 -2.3 -1.3 -0.0 -0.3 0.7 -1.3 0.2 1.3 -0.6 -0.1 -1.7 -0.5
Medication: Ibuprofen (e.g. Nurofen) 2.4 3.0 7.5 -1.4 -1.6 -1.8 -2.1 -2.1 1.9 -1.6 -1.4 -2.7 -1.2 0.9 -1.8 -1.9 -1.2 -1.0 -2.4 -1.4 -1.9 -2.3 -0.9 -1.6
Medication: Cholesterol lowering 1.5 2.3 4.0 1.5 1.5 1.8 1.4 1.8 -1.6 1.9 0.8 1.2 0.6 -0.3 2.0 1.8 1.7 1.5 1.2 1.9 1.9 1.5 0.9 1.9
Depression (self-reported) 0.8 0.9 6.7 0.3 0.9 0.4 0.8 0.5 -0.0 0.6 2.6 -0.5 0.0 1.3 0.5 0.6 0.9 -2.1 1.0 0.5 0.4 0.6 1.1 -0.4
Medication: Lansoprazole 0.5 0.6 1.2 -0.9 -0.9 -0.6 -1.0 -0.2 0.7 -1.0 0.2 -1.0 -1.1 -1.0 -0.3 -0.9 -1.0 -0.4 -0.8 -0.2 -0.7 -0.8 -0.3 -0.1
Prospective memory result 7.0 8.6 14.2 3.4 3.7 3.5 2.5 3.8 -2.8 3.0 2.6 3.7 3.3 1.4 3.2 3.3 2.5 2.1 2.6 1.3 3.3 3.4 1.9 2.5
Lung cancer (father) 1.8 2.2 3.8 -1.9 -1.2 -1.4 -1.7 -1.8 1.5 -1.9 -0.3 -1.4 -1.3 -1.0 -1.2 -1.6 -1.6 -1.9 -1.5 -0.8 -1.5 -1.8 -0.7 -1.4
Illnesses of mother 0.4 0.5 3.2 -0.3 -0.5 -0.9 0.5 -1.2 0.4 -0.2 0.1 -0.8 0.1 0.6 -1.1 -0.5 0.3 -1.8 -0.5 -1.0 -0.7 0.5 0.1 0.1
Forced expiratory volume in 1-second (FEV1), Best measure 0.9 2.8 8.1 -1.8 -1.1 -1.2 -2.0 -1.3 1.9 -1.9 0.1 -2.3 -0.2 -2.5 -1.5 -1.7 -2.2 -1.7 -1.8 -2.9 -1.2 -1.4 1.1 -0.6
Pulse wave Arterial Stiffness index 0.5 0.5 1.9 -0.3 -0.3 -0.5 -1.2 -0.5 0.3 -0.1 0.5 -1.1 -1.2 0.8 -0.3 -0.4 0.3 -0.8 -0.6 1.0 -0.5 -0.9 -0.7 -1.4
Impedance of arm (left) 2.3 10.7 20.4 3.9 3.1 3.8 2.3 3.5 -2.7 4.2 2.1 3.5 2.0 1.2 4.5 3.9 4.0 2.2 4.5 4.2 3.8 2.6 1.9 1.5
Arm fat mass (right) 3.5 14.4 27.1 -4.3 -4.5 -4.5 -2.6 -4.5 4.7 -4.3 -2.8 -4.0 -3.8 -2.0 -4.1 -4.0 -4.1 -1.6 -5.2 -2.9 -4.3 -4.4 -2.9 -0.9
Trunk predicted mass 2.3 12.9 23.0 -4.1 -3.8 -4.0 -3.2 -4.2 3.8 -4.3 -2.8 -3.6 -3.2 -2.2 -4.0 -3.9 -4.3 -2.6 -4.8 -3.3 -3.9 -3.3 -2.4 -1.9
Standing height 0.2 1.5 3.5 -1.1 -1.3 -1.0 -1.9 -1.5 1.1 -1.1 -1.7 -1.1 -1.4 -1.4 -0.3 -1.2 -1.2 -1.0 -1.5 -0.7 -1.0 -1.3 -0.8 -1.2
Length of working week for main job 1.1 1.2 4.7 -0.7 -1.3 -1.3 -0.9 -1.4 1.7 -1.1 0.2 -0.8 -2.2 -0.4 -0.8 -1.1 -0.6 -1.3 -1.1 0.2 -1.2 -1.1 -1.1 -0.4
Exposure to tobacco smoke at home 0.3 0.3 1.7 -0.1 -0.2 -0.4 -0.3 -0.5 0.1 -0.3 -0.9 0.1 -0.7 -0.5 -0.8 -0.3 -0.1 -0.4 -0.1 0.4 -0.3 -1.3 -0.5 -1.1
Breastfed as a baby 0.2 0.2 0.9 -0.3 -0.2 -0.4 0.1 -0.2 0.1 -0.6 -0.8 -0.2 -0.6 -0.1 0.1 -0.5 -0.7 0.3 -0.7 -0.2 -0.4 -1.0 0.1 -0.3
Tense / ‘highly strung’ 6.8 11.2 20.2 4.2 4.2 4.5 1.8 4.5 -2.6 4.3 1.5 3.0 3.5 1.6 3.8 4.4 3.5 1.6 3.1 2.2 4.4 3.6 2.5 2.3
Seen doctor (GP) for nerves, anxiety, tension or depression 0.3 0.4 2.1 0.4 -0.0 -0.3 0.9 -0.3 -0.1 0.5 -1.5 -0.7 -0.1 1.4 -0.4 0.2 1.0 -0.3 -0.8 -0.2 -0.1 -0.4 -0.6 -0.1
Hair/balding pattern: Pattern 4 0.2 0.4 2.9 0.1 0.6 0.2 0.1 0.1 -1.1 -0.2 0.2 0.4 0.7 -0.4 -0.1 -0.3 -0.2 -0.2 0.5 -1.4 0.0 0.4 1.7 -0.1
Birth weight of first child 0.4 0.6 1.8 -0.8 -0.9 -0.8 -0.0 -1.2 0.5 -0.8 -1.0 -0.6 -0.0 -0.0 -0.2 -0.8 -0.6 0.5 -1.1 -1.4 -1.0 -0.8 -1.1 -0.8
Peak expiratory flow (PEF) 2.9 6.8 11.8 -2.8 -3.1 -2.8 -2.3 -2.7 3.4 -3.0 -1.6 -2.8 -2.0 -1.8 -3.0 -2.9 -2.6 -2.1 -3.1 -2.4 -2.8 -3.4 -1.4 -1.5
Pulse wave reflection index 1.2 1.5 5.1 -1.1 -0.9 -1.3 -1.3 -1.3 0.5 -1.1 1.0 -2.3 -2.2 -0.4 -1.1 -1.1 -0.7 -1.7 -0.9 0.4 -1.2 -0.8 -0.4 -1.8
Ever highly irritable/argumentative for 2 days 1.8 2.1 4.0 -1.1 -1.3 -1.7 -1.7 -1.8 1.5 -1.5 -1.9 -1.6 -1.5 -1.3 -1.4 -1.4 -1.4 -0.6 -2.0 -0.8 -1.7 -1.4 -1.5 -0.3
Loud music exposure frequency 0.4 0.4 1.5 0.6 0.3 0.6 -0.8 1.2 -0.5 0.4 0.2 0.3 -0.3 -0.7 0.9 0.5 0.3 1.2 0.4 1.1 0.5 0.6 0.3 0.8
Qualifications: O levels/GCSEs or equivalent 5.0 7.9 14.1 -3.4 -3.0 -3.0 -2.2 -3.0 3.4 -3.1 -1.4 -3.8 -2.6 -1.5 -3.3 -3.1 -2.8 -3.0 -2.8 -2.3 -3.0 -3.2 -1.2 -2.5
Mouth/teeth dental problems: Bleeding gums 1.0 1.3 3.8 1.4 1.4 1.0 1.2 0.8 -1.1 1.2 1.9 1.6 0.4 1.1 0.9 1.2 1.3 0.6 1.0 1.1 0.9 1.1 0.7 0.8
Blood clot in the leg (DVT) 0.3 0.4 2.7 -0.0 0.2 0.0 0.0 0.2 0.5 -0.4 0.3 -0.7 0.2 0.1 0.1 -0.2 -0.7 -1.3 -0.6 -1.6 -0.1 0.6 1.4 0.4
Medication: Paracetamol 3.0 5.0 11.1 -2.1 -2.1 -2.5 -2.9 -2.4 1.9 -2.1 -3.0 -2.9 -2.0 -0.5 -2.3 -2.3 -1.4 -1.4 -3.3 -1.8 -2.5 -2.3 -2.1 -1.5
Headache pain in last month 1.3 2.2 6.4 -0.8 -1.3 -1.5 -2.0 -1.7 0.8 -1.2 -2.5 -1.7 -2.0 0.4 -1.2 -1.2 -1.0 -0.3 -1.9 0.2 -1.5 -2.0 -1.8 -0.8
Medication for cholesterol, blood pressure or diabetes 1.9 3.1 5.0 -2.1 -2.0 -2.1 -1.5 -2.0 2.0 -2.2 -0.4 -1.7 -1.1 -0.8 -1.6 -2.2 -1.8 -1.7 -2.0 -2.0 -2.2 -1.6 -1.2 -1.6
Glaucoma (self-reported) 0.2 0.3 1.6 -0.3 0.1 0.1 -0.9 0.2 -0.1 -0.5 0.8 -0.7 0.2 0.2 -0.0 -0.3 -0.7 0.0 -0.6 -0.2 0.1 -0.1 1.3 -0.4
Gout (self-reported) 0.8 1.1 3.8 -1.3 -1.0 -1.1 -0.6 -1.2 -0.0 -1.2 -0.6 -1.1 -0.2 -0.6 -1.0 -1.3 -1.0 0.0 -1.5 -2.0 -1.2 -0.7 -0.4 -1.5
Hypothyroidism/myxoedema (self-reported) 0.6 1.2 5.6 -1.2 -1.1 -1.1 0.6 -1.7 0.0 -0.8 -0.2 -1.1 -1.9 -2.4 -0.6 -1.0 -0.6 -1.3 0.5 -0.2 -1.1 -0.7 -0.3 -1.4
Medication: Amlodipine 2.1 3.0 5.6 2.0 2.3 1.9 1.1 2.4 -1.7 1.8 1.8 2.0 1.6 1.7 1.6 1.9 1.5 0.7 0.8 0.6 1.8 2.4 2.0 1.3
Medication: Ventolin 100micrograms inhaler 1.5 1.9 7.0 1.9 1.2 0.9 1.5 0.5 -1.1 1.9 1.2 1.3 0.1 0.7 1.7 1.6 2.6 0.2 1.2 1.9 1.0 1.7 -0.8 0.7
Birth weight 0.2 0.3 1.5 -0.1 -0.3 0.1 0.1 0.1 1.2 -0.3 -0.7 0.2 0.4 -0.2 0.7 0.1 -1.0 1.0 -0.6 -0.3 0.2 -0.6 -0.9 0.8
Chronic bronchitis/emphysema (mother) 0.6 0.7 4.8 -0.4 -0.1 -0.7 -0.3 0.3 -0.6 -0.6 -2.2 -0.8 -0.1 -0.1 -0.7 -0.8 -0.0 0.2 -1.0 -0.8 -0.8 -1.0 -1.4 -0.8
High blood pressure (siblings) 0.8 1.1 3.1 0.9 1.3 1.1 0.8 1.1 -1.5 1.1 0.9 -0.1 0.1 -0.7 1.1 1.0 1.3 -0.2 1.8 1.1 1.1 0.8 1.4 -0.2
Forced vital capacity (FVC), Best measure 0.7 2.7 6.6 -1.7 -1.0 -1.1 -1.9 -1.4 1.8 -1.9 0.6 -2.3 -0.4 -1.8 -1.6 -1.6 -2.0 -2.4 -1.6 -2.6 -1.2 -1.4 1.2 -1.2
Body fat percentage 2.5 10.0 16.2 -3.6 -3.9 -3.8 -2.3 -3.6 3.8 -3.6 -2.3 -3.4 -3.5 -2.5 -3.1 -3.4 -3.7 -1.0 -3.7 -1.8 -3.6 -4.0 -2.4 -0.5
Leg fat percentage (right) 3.5 12.6 19.4 -4.1 -4.4 -4.3 -2.5 -4.1 4.2 -4.2 -2.1 -3.6 -3.8 -2.9 -3.9 -3.9 -4.3 -1.6 -4.1 -2.3 -4.0 -4.0 -2.6 -0.5
Arm fat-free mass (right) 3.3 16.8 28.4 -4.7 -4.4 -4.6 -3.8 -4.7 4.2 -5.0 -3.1 -4.2 -3.7 -2.9 -4.4 -4.6 -5.0 -2.5 -5.3 -3.7 -4.5 -4.1 -2.7 -1.9
Exposure to tobacco smoke outside home 1.1 1.4 3.1 -1.3 -1.4 -1.4 -0.7 -0.9 1.4 -1.5 -1.5 -1.1 -1.1 -0.8 -0.8 -1.2 -1.3 -0.5 -1.7 -0.9 -1.2 -1.8 -1.2 -0.1
Comparative body size at age 10 0.1 0.3 2.5 -0.7 -0.2 -0.3 0.8 -0.5 0.4 -0.4 -0.1 0.1 0.3 1.6 -1.0 -0.3 -0.2 -0.6 0.1 -0.5 -0.4 0.0 -0.7 -0.1
Number of full brothers 0.5 0.6 2.3 -0.3 -0.6 -1.0 1.0 -0.6 0.2 -0.1 -1.1 -0.3 -0.1 0.7 -0.9 -0.6 0.3 0.8 -1.2 0.0 -1.0 -0.9 -1.5 -0.6
Worry too long after embarrassment 2.1 3.6 7.2 2.4 2.0 2.1 0.7 1.8 -1.9 2.4 0.3 2.1 1.9 1.3 1.9 2.2 2.7 2.1 1.4 2.1 2.0 2.5 -0.7 1.0
Seen a psychiatrist for nerves, anxiety, tension or depression 1.0 1.4 3.0 1.5 1.0 1.3 1.2 1.4 0.4 1.4 1.5 0.6 0.5 0.9 0.7 1.7 1.2 -1.0 1.4 0.7 1.5 0.6 1.1 1.5
Wheeze or whistling in the chest in last year 0.5 1.0 5.9 1.1 0.1 0.2 0.4 -0.2 -0.3 1.0 -1.2 0.7 -0.9 0.6 0.3 0.9 1.3 0.9 0.1 2.4 0.2 0.5 -1.5 1.6
Number of children fathered 4.1 4.6 8.3 -2.3 -2.9 -2.5 -1.9 -2.2 2.8 -2.3 -0.1 -2.1 -2.5 -2.2 -2.5 -2.3 -2.0 -2.0 -2.6 -1.1 -2.5 -1.8 -1.1 -0.8
Reason for reducing amount of alcohol drunk: Health precaution 1.0 1.2 3.1 1.6 1.2 1.5 0.6 1.2 -0.8 1.3 0.7 0.2 0.7 0.2 1.5 1.4 1.0 0.5 0.8 1.1 1.6 1.8 0.7 0.4
Age at first live birth 0.9 1.5 6.6 -1.3 -0.6 -0.2 -2.6 -0.1 1.5 -1.4 0.7 -0.4 -0.3 -2.1 -0.5 -0.9 -1.8 -1.8 -0.1 -1.5 -0.4 -0.7 1.5 -1.1
Pulse wave peak to peak time 0.4 0.5 1.6 0.2 0.2 0.5 1.0 0.5 -0.2 0.1 -0.5 1.0 1.1 -0.9 0.3 0.3 -0.4 0.7 0.5 -1.0 0.4 0.8 0.7 1.3
Health satisfaction 4.0 5.2 10.2 2.7 2.4 2.4 2.2 2.1 -2.3 2.5 1.8 3.2 0.9 2.5 1.9 2.9 1.9 1.7 1.7 3.0 2.5 1.8 1.6 2.5
Shortness of breath walking on level ground 0.2 0.3 1.7 0.1 -0.4 -0.4 -0.2 -0.2 0.1 0.0 0.1 0.1 -0.6 1.3 -0.4 -0.0 0.2 -0.4 -1.3 0.4 -0.5 0.5 0.0 -0.2
Qualifications: College or University degree 0.2 0.5 2.3 -0.4 -0.6 -0.1 -1.5 0.3 0.8 -0.5 0.8 0.0 -0.8 -1.4 0.4 -0.2 -0.8 -0.6 0.4 0.9 0.0 0.7 0.0 -0.6
Eye problems/disorders: None of the above 0.5 0.6 3.1 -0.4 -1.0 -0.9 0.2 -0.7 1.2 -0.3 -0.8 -0.2 -1.0 0.2 -0.4 -0.6 0.4 -0.3 0.1 0.9 -0.8 -0.8 -1.8 -0.5
Mouth/teeth dental problems: Loose teeth 0.7 0.8 2.5 1.0 1.0 0.7 0.9 1.0 -0.3 0.9 -0.3 1.0 1.2 1.3 0.7 0.7 1.0 -0.6 1.0 -0.6 0.7 0.7 1.6 0.8
Emphysema/chronic bronchitis 0.5 0.5 3.3 -0.4 -0.9 -1.1 0.7 -0.7 0.1 0.1 -1.8 -0.1 -0.7 0.1 -0.6 -0.3 0.6 -0.2 -0.7 -0.0 -0.8 -0.5 -1.3 -0.2
Medication for pain relief, constipation, heartburn 0.6 1.1 3.3 0.6 0.8 0.9 1.8 1.4 -0.4 0.7 1.8 1.5 1.5 0.4 0.8 0.7 0.7 0.2 1.4 -0.3 0.7 1.3 0.8 0.0
Neck or shoulder pain in last month 0.5 0.7 6.5 -0.1 -0.4 -0.3 -0.7 -0.3 -0.3 -0.0 -2.5 -0.4 -1.1 -0.8 -0.3 -0.3 -0.2 0.8 -0.7 1.4 -0.3 -0.4 -1.4 -0.4
Medication: Blood pressure 1.6 2.9 4.9 2.1 2.1 2.0 0.9 2.1 -1.9 2.2 0.7 1.5 1.1 0.7 1.7 2.1 2.1 1.5 1.8 1.8 2.0 1.8 0.8 1.2
Angina (self-reported) 0.8 1.0 2.9 1.3 1.3 1.0 1.4 1.2 -1.3 1.4 0.0 0.6 0.6 0.2 0.9 1.1 1.7 0.5 0.5 0.8 0.9 1.4 -0.4 0.8
Migraine (self-reported) 1.6 2.0 6.8 -1.5 -1.3 -1.2 -1.5 -1.6 1.1 -1.6 -0.9 -1.7 -1.0 -0.5 -1.4 -1.7 -1.9 -1.5 -0.6 -1.1 -1.4 -1.7 -0.1 -2.6
Medication: Ibuprofen 1.7 2.0 5.7 -1.1 -1.4 -1.5 -1.8 -1.4 1.4 -1.3 -1.3 -2.4 -0.6 0.2 -1.2 -1.6 -0.8 -1.0 -2.1 -1.7 -1.7 -1.7 -0.2 -1.2
Medication: Allopurinol 0.4 0.6 1.5 -0.7 -0.6 -0.4 -1.1 -0.5 -0.3 -0.9 -0.8 -0.5 0.2 -1.1 -0.5 -1.0 -0.6 0.8 -0.8 -1.1 -0.7 -0.6 -0.6 -1.2
Medication: Omeprazole 1.1 1.3 2.7 1.4 1.2 1.3 0.8 1.3 -1.2 1.3 1.3 1.0 1.1 -0.5 0.8 1.3 1.0 1.4 0.3 0.6 1.3 1.6 0.7 1.4
Medication: Seretide 50 evohaler 0.3 0.3 1.1 -0.3 -0.4 -0.7 0.5 -1.0 -0.6 -0.0 -1.0 0.5 -0.4 -0.4 0.3 -0.5 0.5 0.5 -0.1 -0.3 -0.9 0.3 -1.1 0.0
Mean time to correctly identify matches 0.4 0.8 2.6 -0.9 -0.8 -0.3 0.5 0.3 0.6 -0.8 -1.3 0.9 0.7 0.0 0.2 -0.4 -1.4 1.6 -0.7 -1.3 -0.2 -1.5 -1.0 1.3
Heart disease (mother) 0.3 0.3 1.2 0.4 0.1 0.5 -0.5 1.1 -0.5 0.2 0.2 0.8 -0.3 -0.2 0.5 0.4 -0.3 0.7 0.6 0.9 0.7 0.3 0.7 0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria 2.5 3.0 8.9 -1.7 -2.0 -1.6 -2.5 -2.3 1.5 -1.5 -0.7 -1.6 -3.0 -1.5 -2.0 -1.7 -1.1 -1.8 -0.8 0.8 -1.6 -1.8 -1.3 -1.8
Whole body fat mass 3.5 14.5 23.2 -4.3 -4.5 -4.5 -2.9 -4.4 4.3 -4.3 -2.9 -3.9 -4.0 -2.5 -3.9 -4.1 -4.3 -1.5 -4.8 -2.5 -4.4 -4.6 -2.9 -1.1
Leg fat mass (right) 5.2 20.0 29.8 -5.0 -5.4 -5.3 -3.6 -5.0 5.2 -5.2 -3.2 -4.6 -4.7 -3.1 -4.9 -4.9 -5.2 -2.4 -5.5 -3.1 -5.1 -5.0 -3.2 -1.3
Arm predicted mass (right) 3.6 18.3 30.8 -4.8 -4.6 -4.9 -3.6 -5.0 4.4 -5.1 -3.4 -4.5 -3.9 -2.7 -4.7 -4.8 -5.0 -2.7 -5.5 -3.7 -4.8 -4.5 -3.0 -2.2
Pulse rate, automated reading 1.0 3.1 7.2 2.1 1.7 1.7 2.7 1.8 -0.9 2.1 1.5 2.4 1.1 1.2 1.6 1.9 2.4 -0.0 1.9 1.2 1.9 2.2 1.2 0.8
Alcohol intake frequency. 2.1 4.9 11.2 -2.7 -3.0 -3.3 -1.0 -3.3 0.8 -2.0 -0.6 -1.5 -3.0 -1.2 -2.7 -2.6 -0.8 -0.8 -2.1 -0.4 -3.1 -2.4 -2.8 -1.5
Comparative height size at age 10 0.1 0.7 2.7 -0.6 -1.1 -1.0 0.0 -1.0 0.6 -0.6 -0.8 -0.7 -1.1 0.6 -0.2 -0.7 -0.9 0.2 -1.1 0.6 -0.8 -1.6 -1.2 -0.8
Number of full sisters 0.2 0.2 0.6 -0.2 0.1 -0.4 -0.8 -0.4 -0.6 -0.3 -0.7 0.3 -0.5 -0.7 0.3 -0.5 0.0 0.4 0.1 0.0 -0.6 0.1 -0.5 -0.7
Suffer from ‘nerves’ 0.3 0.5 1.7 1.1 0.6 0.5 0.0 0.7 -0.2 0.9 0.6 0.4 0.3 0.7 0.9 0.7 1.3 0.6 0.2 1.3 0.4 0.3 -1.0 0.2
Overall health rating 1.5 3.2 8.2 2.2 1.4 1.5 2.0 1.3 -1.8 2.1 0.9 2.0 0.2 2.5 1.6 2.1 2.0 1.8 1.0 2.9 1.7 1.1 0.7 2.3
Chest pain or discomfort 0.2 0.3 1.5 0.4 -0.2 -0.1 0.2 -0.1 0.5 0.6 -0.7 -0.1 -1.1 0.3 0.1 0.4 0.9 -0.9 0.1 1.2 0.1 0.8 -0.5 -0.0
Had major operations 1.1 1.3 3.4 1.2 1.0 1.1 0.7 1.0 -1.2 1.0 -0.9 1.2 0.7 1.0 1.4 1.1 0.8 1.8 0.6 0.9 1.1 1.4 -0.6 1.9
Age at last live birth 0.3 0.4 4.0 -0.3 0.5 0.7 -2.0 0.4 -0.1 -0.2 0.7 -0.3 0.3 -0.7 0.5 0.2 -0.7 0.2 0.3 -0.2 0.5 -0.3 0.8 0.0
Family relationship satisfaction 2.2 2.7 7.0 1.6 1.8 1.6 1.5 0.7 -1.8 1.4 2.7 1.7 -0.1 0.8 2.3 1.8 1.3 -0.0 1.9 1.5 1.7 2.3 1.4 1.9
Leg pain on walking 0.9 1.1 8.8 0.9 0.7 0.6 1.0 1.1 -0.7 1.1 -0.1 0.9 0.3 3.0 0.1 1.0 1.1 0.9 -0.1 1.1 0.6 0.9 -0.2 1.4
Qualifications: NVQ or HND or HNC or equivalent 1.5 1.8 9.0 -1.2 -1.8 -1.2 -0.2 -1.0 3.0 -1.2 -0.5 -0.6 -1.1 -0.8 -2.0 -1.2 -1.4 -1.1 -1.1 -1.0 -1.1 -2.0 -0.3 1.0
Commuting to job workplace: Car/motor vehicle 3.6 4.2 9.6 -2.5 -1.9 -2.3 -1.9 -1.8 1.5 -2.6 -1.4 -2.1 -1.2 -0.9 -3.1 -2.5 -2.5 -1.5 -2.0 -2.3 -2.3 -2.6 -0.3 -1.4
Illness, injury, bereavement, stress in last 2 years 6.3 7.7 12.8 3.0 3.2 3.4 2.5 3.4 -2.7 3.0 2.7 2.7 2.7 0.3 2.9 3.0 2.9 0.7 3.6 1.2 3.4 3.1 3.0 2.0
Medication: Aspirin 1.9 2.5 4.7 1.8 1.5 1.9 1.2 2.0 -1.2 1.7 0.8 1.6 0.4 0.0 2.0 2.0 1.0 0.9 1.8 1.9 2.2 1.5 2.0 1.6
Supplements: Vitamin C 0.5 0.5 2.6 0.7 0.9 0.4 1.1 0.5 -0.8 0.8 1.6 -0.1 0.7 -0.4 0.1 0.6 1.0 -0.5 0.2 0.1 0.5 0.2 1.2 -0.6
Knee pain experienced in last month 0.2 0.4 0.9 0.5 0.9 0.6 0.9 0.8 -0.4 0.4 0.3 -0.1 0.5 -0.4 0.9 0.6 0.6 -0.4 0.3 -0.5 0.6 0.8 0.8 0.8
Hypertension (Self-reported) 0.7 2.1 4.5 1.5 1.0 1.7 0.8 1.8 -0.7 1.7 0.7 1.1 0.1 -0.7 1.6 1.8 1.2 0.3 2.1 1.9 1.8 1.7 1.8 1.8
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported) 0.8 1.0 2.8 0.9 0.3 1.0 0.2 1.2 -1.2 0.7 1.1 1.0 -0.1 -0.6 0.7 1.0 0.0 1.1 0.7 1.7 1.1 1.2 1.6 1.2
Illnesses of father: Heart disease 1.7 2.3 5.6 1.9 0.8 1.1 2.0 1.0 -1.4 1.8 0.7 1.9 0.3 0.8 1.6 1.6 1.9 1.7 1.7 2.0 1.3 1.6 0.4 2.4
Illnesses of siblings: Diabetes 1.0 1.2 4.9 1.3 1.5 1.1 1.2 1.6 -1.7 1.0 0.7 0.6 1.1 0.0 1.0 1.0 0.9 0.6 0.6 0.6 1.0 1.0 2.2 0.1
Smoking status: Previous 2.4 3.6 9.0 -1.7 -1.1 -1.6 -2.3 -1.8 1.4 -2.1 -2.5 -3.0 -1.7 -1.5 -1.7 -2.0 -2.1 -2.1 -2.0 -2.3 -1.5 -1.8 -0.4 -1.3
Forced expiratory volume in 1-second (FEV1), predicted 0.5 1.1 2.7 -0.7 -1.5 -0.7 -1.1 -1.2 1.6 -1.0 -1.6 -0.6 -0.8 -0.9 -1.2 -0.8 -1.1 -1.6 0.1 -0.9 -0.4 -1.1 -0.1 -0.6
Whole body fat-free mass 2.7 15.6 27.9 -4.5 -4.2 -4.4 -3.5 -4.6 4.3 -4.6 -3.2 -4.1 -3.6 -2.4 -4.3 -4.3 -4.6 -2.7 -5.3 -3.5 -4.3 -3.9 -2.5 -2.1
Leg fat-free mass (right) 2.7 14.6 25.5 -4.4 -4.1 -4.2 -3.3 -4.4 4.5 -4.3 -3.3 -4.0 -3.5 -1.9 -4.3 -4.1 -4.3 -2.7 -5.0 -3.5 -4.2 -4.0 -2.4 -2.1
Arm fat percentage (left) 2.4 9.8 17.2 -3.5 -4.0 -3.7 -1.9 -3.6 4.2 -3.5 -2.3 -3.0 -3.4 -2.1 -3.1 -3.2 -3.6 -0.9 -3.9 -1.9 -3.5 -3.9 -2.5 -0.3
Average weekly red wine intake 0.5 0.8 4.2 -0.4 -0.8 0.3 -0.6 0.6 0.8 -0.5 -1.5 1.0 -0.3 -2.0 0.6 -0.2 -1.5 1.6 -0.3 0.5 0.3 -0.7 -0.0 0.2
Handedness (chirality/laterality): Left-handed 0.9 1.1 6.2 1.0 0.6 0.4 1.0 0.3 -1.5 1.2 0.0 0.3 -0.2 2.2 0.4 0.7 1.4 1.4 0.9 2.5 0.3 0.1 0.0 -0.5
Mood swings 0.2 0.4 2.3 0.1 -0.1 -0.0 -1.4 0.2 1.5 -0.1 -0.7 -0.6 -0.7 -0.2 -0.7 0.1 -0.0 -1.1 -0.5 0.6 0.0 -0.3 -0.7 -0.2
Loneliness, isolation 0.2 0.3 1.1 0.8 0.7 0.4 -0.3 0.2 -0.7 0.7 0.5 -0.4 0.5 0.9 0.3 0.6 1.1 0.1 0.5 0.5 0.3 0.2 0.2 0.0
Long-standing illness, disability or infirmity 0.4 0.7 4.1 0.5 -0.1 0.3 1.5 0.2 -0.1 0.8 0.4 0.5 -1.2 0.7 0.6 0.8 0.9 0.3 0.1 2.0 0.3 0.2 -0.4 1.3
Ever had bowel cancer screening 3.9 4.6 8.8 2.5 2.3 2.2 2.3 2.5 -3.0 2.5 0.7 2.8 1.9 1.4 2.0 2.4 2.1 2.6 1.5 1.8 2.2 2.1 1.4 1.4
Diabetes diagnosed by doctor 1.0 1.6 3.3 -1.5 -1.2 -1.3 -1.4 -1.6 1.6 -1.3 0.3 -1.4 -1.8 -1.8 -1.6 -1.0 -1.2 -1.3 -1.5 -0.2 -1.2 -1.1 -0.2 -0.4
Ever had stillbirth, spontaneous miscarriage or termination 0.9 1.0 4.2 1.0 0.7 0.4 1.2 -0.0 -0.6 0.9 0.5 1.6 -0.0 1.5 0.2 1.0 1.2 0.1 1.5 2.0 0.6 -0.1 -1.2 1.1
Friendships satisfaction 1.1 1.3 2.9 1.2 1.3 1.1 1.6 0.3 -1.1 1.2 1.3 1.0 1.1 1.7 1.1 1.4 1.4 1.0 0.5 0.7 1.1 0.7 0.7 1.6
Qualifications: nursing, teaching 0.3 0.5 2.4 -1.0 -0.8 -0.7 0.0 -1.1 0.6 -0.8 0.5 0.1 -1.5 0.1 -0.3 -0.8 -0.8 -0.5 -0.4 0.0 -0.7 -1.1 -0.4 -0.5
Commuting to job workplace: Walk 5.0 5.4 12.6 2.8 2.1 2.8 1.3 2.3 -3.0 3.0 1.1 2.4 1.6 0.6 3.5 2.6 2.8 2.4 2.1 2.5 2.4 2.6 1.6 0.8
Eye problems/disorders: Cataract 1.0 1.1 2.9 1.1 1.2 1.1 1.1 1.4 -1.7 1.0 0.6 1.0 1.1 0.3 1.0 1.0 0.6 1.4 0.1 -0.1 0.9 1.6 1.2 0.7
Mouth/teeth dental problems: Mouth ulcers 0.1 0.2 1.6 0.4 0.5 0.2 -0.4 0.0 -0.8 -0.0 -0.1 0.7 0.5 0.1 0.6 0.2 0.3 1.3 -0.1 0.4 0.1 0.4 -0.5 0.1
Medication for cholesterol 1.0 1.5 3.5 -0.6 -0.6 -1.5 -0.5 -1.3 0.5 -1.1 -1.5 -1.1 -0.5 1.6 -1.6 -1.3 -0.6 -0.5 -1.6 -1.4 -1.5 -1.6 -1.9 -1.0
Medication: Laxatives (e.g. Dulcolax, Senokot) 0.3 0.4 1.0 0.9 0.7 0.7 0.2 0.8 -0.1 0.6 0.3 0.9 0.6 0.1 0.9 0.6 0.6 0.4 0.7 0.3 0.6 0.5 -0.4 1.0
Back pain experienced in last month 1.1 1.6 5.8 -0.7 -1.1 -1.3 -0.8 -1.3 -0.2 -0.9 -2.4 -0.9 -2.2 0.7 -1.3 -1.1 -0.5 -0.4 -2.0 0.7 -1.4 -0.5 -2.1 -1.2
Mineral and other dietary supplements 0.5 0.7 2.7 0.5 1.0 0.7 -1.6 -0.2 -0.5 0.8 0.9 0.2 -0.3 0.1 1.3 0.7 1.2 -0.4 1.0 1.6 0.7 0.7 -0.7 0.2
Breast cancer (self-reported) 1.1 1.3 3.1 -1.4 -1.4 -1.5 -1.2 -0.9 0.5 -1.1 -1.8 -0.8 -1.1 -1.0 -0.9 -1.4 -1.0 0.3 -1.5 -0.5 -1.5 -0.9 -1.0 -0.6
Asthma (self-reported) 0.3 0.7 4.5 0.1 -0.7 -0.4 -0.2 -0.5 0.6 0.3 0.4 0.0 -2.1 -1.2 0.3 0.0 0.9 -1.1 0.3 1.5 -0.4 0.2 -1.6 -0.3
Osteoporosis (self-reported) 4.9 6.0 11.5 2.9 2.4 2.5 3.0 1.9 -2.8 3.4 1.5 3.0 1.4 1.1 2.6 3.0 3.3 1.9 2.2 2.6 2.6 2.7 1.0 1.6
Osteoarthritis (self-reported) 0.5 0.6 2.4 1.0 -0.0 0.2 0.8 0.7 -0.9 0.6 -0.6 0.7 0.1 1.5 0.5 0.6 0.6 1.2 0.5 1.5 0.3 0.9 -0.5 0.9
Medication: Aspirin 1.7 2.3 4.7 1.6 1.3 1.9 1.0 1.9 -0.8 1.6 0.6 1.6 0.4 0.3 2.1 1.9 0.9 0.9 1.8 1.8 2.2 1.4 1.8 1.9
Medication: Gliclazide 0.4 0.4 1.3 -0.7 -0.5 -0.7 0.5 -0.8 0.7 -0.7 0.4 -0.4 -0.7 -0.5 -1.1 -0.4 -1.1 -0.4 -0.8 -0.1 -0.5 -0.3 0.3 0.9
Illnesses of father: None of the above (group 1) 0.8 1.0 8.5 -1.2 -0.7 -0.9 -0.4 -0.5 0.6 -0.8 -0.4 -0.9 -0.3 -0.8 -0.6 -1.0 -0.4 -1.1 -1.2 -0.8 -0.9 -1.1 -0.6 -2.9
Smoking status: Current 0.1 0.2 0.8 0.1 0.1 -0.3 0.3 -0.6 0.3 0.1 0.3 -0.8 -0.0 0.5 -0.3 0.1 0.2 -0.6 -0.9 -0.3 -0.1 0.2 -0.1 0.5
Forced expiratory volume in 1-second (FEV1), predicted percentage 0.3 0.7 3.7 -0.6 -0.1 -0.1 -0.2 0.3 0.4 -0.9 1.2 -0.3 1.1 -0.4 -0.4 -0.5 -1.4 0.4 -0.5 -1.9 -0.1 -0.2 1.7 1.0
Whole body water mass 2.6 14.7 26.6 -4.4 -4.1 -4.3 -3.3 -4.5 4.2 -4.5 -3.0 -4.0 -3.5 -2.2 -4.3 -4.2 -4.5 -2.7 -5.2 -3.5 -4.2 -3.8 -2.4 -2.0
Leg predicted mass (right) 2.8 14.7 26.3 -4.4 -4.1 -4.2 -3.3 -4.4 4.5 -4.3 -3.3 -4.0 -3.4 -1.9 -4.3 -4.1 -4.3 -2.7 -5.1 -3.5 -4.2 -4.0 -2.4 -2.1
Arm fat mass (left) 3.6 14.7 26.4 -4.3 -4.6 -4.5 -2.6 -4.4 4.7 -4.4 -2.8 -3.9 -3.9 -2.3 -4.1 -4.1 -4.3 -1.6 -5.1 -2.9 -4.4 -4.4 -2.8 -0.9
Number of self-reported non-cancer illnesses 0.5 0.8 2.9 0.7 0.1 0.5 1.7 0.6 -0.1 0.9 1.3 0.2 -0.7 -1.1 0.8 0.8 0.7 -0.3 0.7 1.1 0.7 1.0 0.5 1.6
Average weekly champagne plus white wine intake 0.8 1.1 2.1 0.9 1.1 1.0 1.0 0.3 -1.1 1.1 1.3 0.8 0.5 1.3 1.4 1.1 1.0 1.2 1.3 1.4 1.0 0.8 0.2 0.6
Miserableness 0.1 0.2 1.3 0.4 -0.2 -0.3 -1.1 0.1 0.8 0.1 -0.3 -0.3 -0.4 -0.1 -0.5 0.1 0.1 -0.0 -0.3 0.9 -0.1 -0.9 -0.5 -0.4
Guilty feelings 0.4 0.5 1.4 1.2 0.9 0.7 -0.3 0.9 -0.8 0.7 0.0 -0.0 1.1 0.6 0.2 0.7 1.1 0.9 -0.1 0.3 0.7 0.8 -0.7 -0.6
Wears glasses or contact lenses 0.3 0.3 1.4 0.1 -0.3 -0.3 0.8 -0.5 0.4 -0.2 -1.0 0.5 -1.0 1.0 0.0 -0.0 -0.4 -0.6 0.1 0.6 -0.0 -1.2 0.2 -0.6
Ever taken oral contraceptive pill 4.6 5.1 11.8 -2.3 -2.2 -1.9 -2.6 -2.3 3.0 -2.7 -1.4 -2.3 -1.7 -2.1 -2.7 -2.3 -3.2 -1.6 -2.2 -1.3 -1.8 -3.4 -1.2 -1.6
Hearing aid user 1.3 1.4 3.5 -1.4 -1.1 -1.2 -0.8 -1.1 0.7 -1.3 -0.9 -1.0 -1.6 -0.9 -1.4 -1.5 -1.3 -1.1 -1.3 -0.6 -1.3 -1.9 -0.6 -1.3
Mother’s age at death 1.6 2.0 3.6 1.3 1.7 1.8 1.1 1.8 -1.5 1.3 0.1 1.7 1.9 1.1 1.6 1.5 1.0 1.1 1.7 0.3 1.9 1.6 1.0 1.3
Financial situation satisfaction 0.2 0.2 2.0 0.7 0.7 0.2 0.5 -0.1 -0.5 0.2 0.3 0.2 -0.2 1.4 0.5 0.5 0.2 0.0 -0.1 0.3 0.3 -0.1 -0.3 0.5
Tinnitus: Yes, now most or all of the time 0.1 0.1 1.5 0.3 0.2 0.1 0.5 -0.2 0.6 -0.0 1.2 0.3 0.1 -0.3 -0.1 0.1 -0.1 -0.4 -0.2 0.2 0.1 -0.6 0.1 0.2
Commuting to job workplace: Public transport 0.7 0.9 2.9 0.3 -0.4 -0.6 0.9 -1.1 0.5 0.4 1.5 -0.5 -1.7 0.7 0.2 0.2 1.3 -1.6 -0.1 1.7 -0.4 0.4 -1.2 -0.8
Eye problems/disorders: Glaucoma 0.3 0.4 2.7 0.2 0.4 0.7 -0.7 0.6 -0.5 0.2 1.2 -0.2 0.3 0.4 0.3 0.4 -0.3 0.1 -0.0 0.7 0.7 0.4 1.6 -0.1
Medication: Blood pressure 1.7 3.3 7.8 1.5 1.6 2.2 1.0 1.7 -1.0 2.0 2.1 1.7 0.4 -0.4 2.4 2.3 1.4 0.3 2.3 2.8 2.3 2.0 2.3 1.8
Pain type(s) experienced in last month: Hip pain 0.7 0.9 4.6 -0.6 -1.0 -0.9 0.4 -0.8 -0.3 -0.6 -2.1 -0.7 -0.9 0.2 -0.6 -0.7 -0.9 0.8 -2.0 -0.4 -0.9 -0.4 -1.1 0.1
Supplements: Fish oil (including cod liver oil) 0.4 0.5 2.9 -0.6 -0.5 -0.2 1.7 0.5 0.2 -0.6 -0.4 -0.5 0.1 -0.0 -0.9 -0.4 -1.0 -0.0 -0.6 -1.1 -0.4 -0.6 0.6 -1.3
High cholesterol (Self-reported) 1.4 2.5 6.6 1.4 1.4 1.8 1.1 1.7 -1.6 1.8 1.3 1.4 1.2 -0.5 1.8 1.8 1.1 1.6 1.2 0.8 1.8 2.3 1.7 2.6
Medication: Bendroflumethiazide 1.1 1.6 4.2 1.0 1.0 1.1 1.0 0.9 -1.4 1.4 1.5 1.2 0.1 -0.5 2.1 1.3 1.5 1.4 1.7 1.8 1.1 1.5 0.6 1.0
Medication: Paracetamol 2.4 3.8 10.2 -1.8 -1.9 -2.2 -1.8 -1.7 1.5 -1.8 -2.9 -2.3 -1.1 0.6 -2.3 -2.1 -1.0 -1.4 -3.2 -2.7 -2.2 -1.6 -1.3 -1.1
Medication: Lisinopril 5.5 7.2 14.6 2.9 2.8 3.7 0.8 3.4 -1.4 3.0 1.4 1.9 2.5 0.6 3.2 3.6 2.0 1.0 3.2 2.0 3.8 3.0 3.4 2.7
Medication: Atorvastatin 3.2 4.0 8.5 2.1 1.9 2.3 2.0 2.9 -1.5 2.6 2.0 1.2 1.6 1.2 1.7 2.4 2.1 1.6 1.5 1.1 2.4 2.0 1.4 2.9
Illnesses of father: High blood pressure 4.1 5.1 8.4 2.6 1.6 2.4 1.9 2.4 -1.7 2.8 1.3 2.6 1.4 1.6 2.5 2.9 2.8 2.2 2.9 2.7 2.5 1.5 0.4 2.7
Alcohol drinker status: Never 0.4 0.5 2.5 -0.4 -0.4 -0.7 1.6 -0.6 -0.7 0.1 1.2 -0.3 -1.1 -0.3 -0.3 -0.1 0.6 -0.5 0.6 1.0 -0.6 -0.2 -0.7 -0.7
Ever smoked 1.2 2.2 6.4 -1.5 -0.5 -1.0 -1.9 -1.4 1.1 -1.7 -0.9 -2.5 -1.2 -1.0 -1.7 -1.4 -2.0 -2.3 -1.4 -1.8 -0.9 -1.3 1.0 -1.0
Basal metabolic rate 3.2 17.6 31.5 -4.8 -4.6 -4.7 -3.6 -4.9 4.6 -4.8 -3.4 -4.5 -4.0 -2.4 -4.6 -4.5 -4.8 -2.8 -5.6 -3.6 -4.6 -4.3 -2.8 -2.1
Leg fat percentage (left) 3.6 13.1 19.8 -4.2 -4.3 -4.3 -2.6 -4.0 4.4 -4.3 -2.1 -3.7 -3.5 -2.8 -3.9 -4.0 -4.4 -1.6 -4.3 -2.7 -4.1 -4.2 -2.5 -0.4
Arm fat-free mass (left) 3.2 16.3 30.1 -4.6 -4.2 -4.6 -3.3 -4.7 4.2 -4.8 -2.6 -4.4 -3.4 -2.3 -4.6 -4.5 -4.7 -2.7 -5.5 -4.0 -4.5 -4.0 -2.5 -2.0
Number of operations (self-reported) 1.1 1.6 4.9 1.2 1.3 1.1 0.7 1.3 -1.3 0.9 0.8 1.8 1.4 1.0 1.7 1.1 0.7 1.5 0.8 0.5 1.1 1.9 0.1 2.2
Average weekly beer plus cider intake 1.6 2.3 8.7 -0.9 -1.4 -2.0 -0.6 -1.6 1.3 -1.1 -0.1 -2.4 -2.2 0.6 -1.9 -1.3 -0.4 -2.9 -0.9 -0.5 -1.8 -1.2 -1.0 -1.9
Irritability 0.7 1.3 4.9 0.1 0.4 1.3 -2.0 1.5 1.5 -0.2 0.4 -0.3 0.2 -2.1 0.0 0.7 -1.1 -1.5 0.5 -0.8 1.2 -0.1 2.2 0.4
Risk taking 0.6 0.8 3.8 -1.1 -0.7 -0.7 -1.1 -1.1 1.6 -0.9 0.4 -0.9 -0.8 -0.6 -0.3 -0.6 -0.9 -2.0 0.0 -0.9 -0.6 0.0 0.3 0.9
Ever had prostate specific antigen (PSA) test 0.3 0.4 3.0 -0.4 -0.2 -0.5 0.4 -0.4 0.1 -0.7 -0.4 -0.3 0.6 -0.2 -0.4 -0.7 -0.9 0.3 -0.7 -1.7 -0.5 -1.0 -0.0 0.4
Fractured/broken bones in last 5 years 0.3 0.4 1.3 0.7 0.4 0.1 0.6 0.3 -1.1 0.7 -0.7 -0.0 0.2 0.2 0.7 0.2 1.1 1.0 0.2 -0.2 0.2 -0.2 -1.1 -0.6
Age started oral contraceptive pill 6.8 8.6 16.1 3.4 3.5 3.6 1.7 4.0 -3.5 3.1 1.9 3.2 3.2 1.1 3.5 3.4 2.4 2.5 2.4 1.1 3.6 3.1 2.6 2.1
Diastolic blood pressure, automated reading 0.1 0.4 3.5 0.2 0.0 0.5 -0.8 0.5 0.7 -0.1 0.5 0.5 0.0 -1.9 0.3 0.3 -0.8 -0.2 1.0 0.3 0.6 0.0 0.4 0.9
Ever depressed for a whole week 0.6 0.7 2.1 1.0 0.4 0.6 -0.6 0.8 -0.6 1.1 -1.4 -0.5 -0.5 -0.1 0.8 1.0 1.0 0.7 -1.1 1.4 0.5 1.0 -0.4 -0.4
Unable to work because of sickness or disability 0.5 0.7 2.1 0.9 1.0 0.6 -0.3 0.4 -1.2 0.9 -1.5 0.1 0.6 1.0 0.2 0.8 1.0 0.9 -0.0 1.1 0.8 0.0 -1.4 0.3
Commuting to job workplace: Cycle 0.9 1.1 2.1 1.2 0.7 1.0 1.1 0.7 -0.5 1.3 1.2 1.2 1.5 1.1 0.6 1.1 1.4 0.9 0.8 0.3 1.1 1.4 0.7 1.3
Myopia 0.7 1.0 2.7 1.0 1.0 1.0 0.7 1.5 -0.9 1.0 -0.1 1.6 0.4 1.1 1.0 1.0 0.8 1.0 0.9 1.6 0.9 0.9 0.1 0.3
Vascular/heart problems diagnosed by doctor 1.3 3.5 7.5 -2.1 -1.7 -2.3 -1.1 -2.2 1.3 -2.4 -0.7 -1.4 -0.7 0.3 -2.4 -2.4 -2.0 -1.1 -2.6 -2.7 -2.4 -1.9 -1.1 -2.0
Cholesterol lowering medication 2.2 3.3 8.4 1.5 1.8 2.2 0.7 2.1 -1.4 1.9 2.3 1.4 1.4 -0.1 2.0 2.3 1.0 1.3 1.2 1.4 2.1 2.6 2.1 2.9
Medication: Omeprazole (e.g. Zanprol) 0.5 0.6 1.4 0.9 0.9 0.9 0.1 1.2 -0.7 0.6 0.6 0.8 0.5 -1.1 0.3 0.8 0.1 0.8 0.1 0.3 1.0 1.1 0.5 1.2
Pain experienced in last month 0.4 0.6 3.8 -0.7 -0.7 -0.2 -0.2 0.1 1.7 -0.4 1.9 -0.2 0.8 -0.3 -0.5 -0.3 -0.4 -0.8 0.2 -1.1 -0.0 -0.2 1.4 -0.4
Supplements: Calcium 0.2 0.2 1.3 0.4 -0.4 -0.5 1.2 -0.4 -0.6 0.3 0.1 0.5 -0.5 0.6 -0.2 -0.0 0.9 -0.2 -0.2 0.3 -0.2 0.1 0.2 0.0
Basal cell carcinoma (self-reported) 1.3 1.5 5.0 -1.1 -1.0 -0.9 -1.4 -1.4 1.5 -1.1 -1.1 -1.5 -1.4 -1.9 -0.9 -1.0 -1.0 -2.2 -0.2 -0.7 -0.8 -0.7 0.3 -1.8
Heart attack/myocardial infarction (self-reported) 1.6 2.1 13.6 1.7 0.3 0.9 0.7 0.9 -1.0 1.7 0.2 1.0 -1.5 0.5 2.3 1.4 2.2 0.8 1.2 3.7 0.9 0.7 -0.7 1.1
Deep venous thrombosis (DVT) (self-reported) 0.4 0.5 2.5 -0.1 0.2 -0.0 -0.3 0.2 0.6 -0.5 0.4 -0.6 0.1 -0.2 0.1 -0.3 -0.8 -1.5 -0.6 -1.6 -0.1 0.6 1.4 0.3
Heart disease (siblings) 0.8 1.0 2.6 1.2 0.5 1.3 0.5 1.4 -0.5 1.2 0.3 0.5 0.8 -0.2 1.6 1.1 0.7 1.4 0.8 1.3 1.2 0.7 0.2 1.2
Alcohol drinker status: Previous 0.5 0.6 2.3 -1.1 -0.6 -0.8 -0.9 -0.4 0.5 -1.0 0.6 -0.2 0.1 -0.9 -1.0 -0.8 -0.5 0.3 -1.5 -1.1 -0.9 -0.7 -0.2 -0.2
Pack years of smoking 0.6 0.9 6.4 1.1 0.6 0.6 -1.2 0.3 -1.2 0.8 -0.9 0.5 -0.7 -0.5 0.2 0.7 0.8 0.3 1.1 2.5 0.8 0.4 -1.3 -0.4
Impedance of whole body 1.3 6.8 15.1 3.2 2.6 3.0 1.6 2.8 -2.4 3.3 2.1 2.5 1.8 0.8 3.6 2.9 3.3 1.5 3.9 3.4 3.0 1.9 1.3 1.0
Leg fat mass (left) 4.9 19.1 28.8 -4.9 -5.2 -5.2 -3.4 -4.9 5.2 -5.1 -3.1 -4.5 -4.5 -2.9 -4.8 -4.8 -5.1 -2.3 -5.4 -3.1 -4.9 -5.0 -3.1 -1.1
Arm predicted mass (left) 3.1 15.6 30.9 -4.5 -4.1 -4.5 -3.5 -4.6 4.1 -4.7 -2.4 -4.3 -3.4 -2.3 -4.5 -4.4 -4.7 -2.6 -5.6 -3.9 -4.4 -3.8 -2.3 -1.8