[Hub]/) : Traits : Arm fat mass (left) : ← →

chr17:44,788,310-47,718,188

Best TWAS P=3.79e-12 · Best GWAS P=6.29e-13 conditioned to 4.82e-06

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
36	The Cancer Genome Atlas	Prostate Adenocarcinoma	CDK5RAP3	0.06	0.00	blup	62	0.03	1.0e-03	-4.01	-6.9	3.8e-12	-0.35	0.01	0.79	TRUE
3	CommonMind	Brain Pre-frontal Cortex	SNF8	0.08	0.07	lasso	5	0.08	9.3e-10	-4.73	5.9	3.5e-09	0.07	0.06	0.94	TRUE
31	YFS	Blood	UBE2Z	0.06	0.03	enet	19	0.06	1.5e-18	2.66	5.8	5.6e-09	0.10	1.00	0.00	TRUE
19	GTEx	Liver	ARL17A	0.34	0.18	lasso	9	0.18	9.8e-06	4.53	5.4	7.0e-08	-0.04	0.00	0.52	TRUE
20	GTEx	Muscle Skeletal	AC003665.1	0.05	0.03	enet	8	0.03	1.4e-03	5.45	6.8	1.4e-11	0.63	0.11	0.74	FALSE
23	GTEx	Pancreas	CDK5RAP3	0.11	-0.01	lasso	4	0.02	5.1e-02	5.25	-6.5	7.9e-11	-0.48	0.09	0.18	FALSE
27	GTEx	Testis	RP11-6N17.4	0.14	0.02	lasso	10	0.02	4.8e-02	6.38	6.4	1.6e-10	0.78	0.13	0.75	FALSE
35	The Cancer Genome Atlas	Prostate Adenocarcinoma	CBX1	0.03	0.04	lasso	4	0.04	3.7e-05	6.44	-6.3	2.4e-10	-0.84	0.01	0.99	FALSE
26	GTEx	Stomach	RP11-6N17.9	0.13	0.02	lasso	6	0.04	8.0e-03	5.66	-6.3	2.6e-10	-0.70	0.11	0.70	FALSE
9	GTEx	Brain Cerebellar Hemisphere	CDK5RAP3	0.22	0.10	lasso	6	0.09	2.6e-03	5.25	-6.3	3.2e-10	-0.74	0.08	0.44	FALSE
17	GTEx	Heart Atrial Appendage	CDK5RAP3	0.13	0.00	enet	18	0.04	5.1e-03	1.78	-6.2	4.2e-10	-0.42	0.09	0.05	FALSE
24	GTEx	Pancreas	RP11-6N17.9	0.15	0.04	lasso	5	0.04	9.3e-03	-2.62	-6.2	5.0e-10	-0.47	0.13	0.17	FALSE
12	GTEx	Brain Nucleus accumbens basal ganglia	CDK5RAP3	0.21	0.04	lasso	4	0.02	7.2e-02	6.39	-6.2	5.2e-10	-0.78	0.07	0.44	FALSE
30	GTEx	Thyroid	RP11-6N17.10	0.19	0.12	lasso	5	0.13	3.0e-10	-4.50	-6.0	1.6e-09	-0.47	1.00	0.00	FALSE
8	GTEx	Brain Caudate basal ganglia	RP11-6N17.9	0.45	-0.01	enet	28	0.16	3.3e-05	-0.85	-6.0	2.3e-09	-0.48	0.06	0.17	FALSE
15	GTEx	Esophagus Gastroesophageal Junction	RP11-6N17.9	0.18	0.14	lasso	3	0.09	4.9e-04	-4.50	-6.0	2.5e-09	-0.49	0.03	0.72	FALSE
28	GTEx	Thyroid	CDK5RAP3	0.21	0.14	lasso	5	0.18	1.6e-13	-4.50	-5.9	3.2e-09	-0.51	1.00	0.00	FALSE
6	GTEx	Artery Aorta	RP11-6N17.10	0.20	0.07	enet	24	0.14	3.5e-08	-4.50	-5.9	3.6e-09	-0.43	0.43	0.23	FALSE
2	CommonMind	Brain Pre-frontal Cortex	CDK5RAP3	0.15	0.12	bslmm	392	0.14	3.6e-16	6.08	-5.9	4.0e-09	-0.78	0.34	0.66	FALSE
10	GTEx	Brain Cerebellar Hemisphere	RP11-6N17.10	0.21	0.16	lasso	5	0.13	3.8e-04	5.25	-5.9	4.5e-09	-0.73	0.08	0.46	FALSE
33	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	CBX1	0.03	0.01	lasso	3	0.01	8.7e-03	6.39	-5.8	5.7e-09	-0.80	0.01	0.81	FALSE
13	GTEx	Brain Nucleus accumbens basal ganglia	RP11-6N17.9	0.47	0.05	lasso	17	0.11	8.3e-04	5.66	-5.8	7.9e-09	-0.65	0.10	0.47	FALSE
14	GTEx	Esophagus Gastroesophageal Junction	CDK5RAP3	0.21	0.09	lasso	6	0.07	1.2e-03	-4.50	-5.8	8.9e-09	-0.30	0.09	0.50	FALSE
32	The Cancer Genome Atlas	Breast Invasive Carcinoma	CDK5RAP3	0.05	0.03	lasso	2	0.02	1.8e-05	5.66	-5.7	9.3e-09	-0.76	0.00	1.00	FALSE
29	GTEx	Thyroid	RP11-6N17.9	0.22	0.14	lasso	5	0.14	5.2e-11	-4.50	-5.7	9.8e-09	-0.44	1.00	0.00	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ATP5G1	0.07	0.05	lasso	3	0.06	4.7e-08	-4.91	5.5	4.6e-08	0.08	0.94	0.06	FALSE
21	GTEx	Nerve Tibial	CDK5RAP3	0.41	0.35	enet	23	0.36	6.1e-27	-4.50	-5.5	4.7e-08	-0.41	1.00	0.00	FALSE
18	GTEx	Heart Left Ventricle	ATP5G1	0.24	0.22	lasso	4	0.22	9.3e-12	-5.11	5.5	4.8e-08	0.12	0.99	0.01	FALSE
22	GTEx	Nerve Tibial	RP11-6N17.10	0.28	0.19	lasso	8	0.19	1.6e-13	-4.50	-5.4	8.0e-08	-0.36	1.00	0.00	FALSE
34	The Cancer Genome Atlas	Brain Lower Grade Glioma	ATP5G1	0.08	0.02	enet	7	0.02	3.1e-03	-4.64	5.3	9.2e-08	0.10	0.02	0.75	FALSE
16	GTEx	Esophagus Muscularis	SNF8	0.08	0.03	lasso	3	0.01	5.7e-02	-5.47	5.3	1.1e-07	0.08	0.02	0.80	FALSE
5	GTEx	Artery Aorta	RP11-6N17.9	0.23	0.12	enet	19	0.19	9.5e-11	-4.50	-5.3	1.2e-07	-0.42	0.98	0.01	FALSE
11	GTEx	Brain Nucleus accumbens basal ganglia	KPNB1	0.24	0.00	lasso	9	0.01	2.1e-01	0.97	-5.3	1.2e-07	-0.80	0.02	0.79	FALSE
37	The Cancer Genome Atlas	Thyroid Carcinoma	ATP5G1	0.19	0.03	lasso	3	0.08	4.4e-08	3.77	5.3	1.2e-07	0.08	0.01	0.99	FALSE
25	GTEx	Skin Not Sun Exposed Suprapubic	UBE2Z	0.11	0.07	lasso	6	0.04	1.8e-03	-5.47	5.3	1.3e-07	0.08	0.10	0.14	FALSE
7	GTEx	Artery Coronary	PNPO	0.13	0.00	lasso	4	-0.01	5.9e-01	4.59	5.3	1.4e-07	0.24	0.13	0.06	FALSE
4	GTEx	Artery Aorta	CDK5RAP3	0.26	0.22	lasso	11	0.25	5.8e-14	-4.50	-5.2	1.7e-07	-0.35	1.00	0.00	FALSE