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chr19:32,209,988-34,959,979

Best TWAS P=7.25e-15 · Best GWAS P=3.17e-14 conditioned to 0.0878

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
9	The Cancer Genome Atlas	Colon Adenocarcinoma	PEPD	0.13	0.06	blup	113	0.10	1.2e-06	5.0	7.8	7.3e-15	0.86	0.01	0.99	TRUE
1	CommonMind	Brain Pre-frontal Cortex	DPY19L3	0.07	0.05	lasso	2	0.06	8.7e-08	-5.4	-5.4	6.2e-08	-0.01	0.01	0.99	TRUE
12	The Cancer Genome Atlas	Liver Hepatocellular Carcinoma	PEPD	0.16	0.07	lasso	3	0.05	3.1e-03	7.4	7.3	2.6e-13	0.95	0.01	0.96	FALSE
5	GTEx	Esophagus Mucosa	PEPD	0.37	0.32	enet	20	0.39	9.5e-28	5.7	7.0	2.7e-12	0.87	0.03	0.97	FALSE
8	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	PEPD	0.06	0.01	blup	114	0.04	2.6e-04	7.5	6.9	6.2e-12	0.84	0.01	0.96	FALSE
3	GTEx	Breast Mammary Tissue	PEPD	0.16	0.06	lasso	4	0.04	3.5e-03	5.7	6.0	1.9e-09	0.78	0.43	0.52	FALSE
6	METSIM	Adipose	CHST8	0.22	0.17	lasso	4	0.17	3.7e-25	5.7	5.9	2.9e-09	0.73	1.00	0.00	FALSE
7	METSIM	Adipose	PEPD	0.19	0.18	lasso	5	0.17	2.3e-24	5.7	5.7	1.0e-08	0.73	1.00	0.00	FALSE
4	GTEx	Colon Transverse	PEPD	0.14	0.16	lasso	2	0.13	1.2e-06	5.7	5.6	2.4e-08	0.71	0.64	0.22	FALSE
13	The Cancer Genome Atlas	Thyroid Carcinoma	DPY19L3	0.05	0.04	enet	9	0.05	2.1e-05	-5.0	-5.3	8.6e-08	-0.02	0.02	0.97	FALSE
10	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	PEPD	0.04	0.05	blup	113	0.03	1.9e-04	-4.9	5.3	1.1e-07	0.53	0.51	0.24	FALSE
11	The Cancer Genome Atlas	Brain Lower Grade Glioma	ZNF507	0.05	0.03	blup	39	0.05	1.3e-06	-5.0	-5.3	1.1e-07	-0.04	0.01	0.99	FALSE
14	The Cancer Genome Atlas	Thyroid Carcinoma	ZNF507	0.14	0.14	lasso	5	0.18	2.4e-17	-4.9	-5.2	1.8e-07	-0.04	0.01	0.99	FALSE
2	GTEx	Adipose Subcutaneous	PEPD	0.30	0.25	lasso	6	0.26	2.5e-21	5.7	5.2	2.3e-07	0.73	1.00	0.00	FALSE