Best TWAS P=4.63e-09 · Best GWAS P=2.59e-24 conditioned to 5.44e-19
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells EBV-transformed lymphocytes | SAE1 | 0.21 | 0.09 | lasso | 3 | 0.07 | 2.0e-03 | -3.8 | -5.9 | 4.6e-09 | 0.77 | 0.06 | 0.67 | TRUE |
| 2 | METSIM | Adipose | SAE1 | 0.12 | 0.04 | lasso | 5 | 0.07 | 1.7e-10 | -4.4 | -5.5 | 4.8e-08 | 0.61 | 0.61 | 0.39 | FALSE |