Best TWAS P=5.91e-13 · Best GWAS P=1.88e-12 conditioned to 0.067
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Aorta | AFF3 | 0.14 | 0.06 | lasso | 5 | 0.07 | 1.2e-04 | -7.0 | -7.2 | 5.9e-13 | 0.84 | 0.01 | 0.99 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | LONRF2 | 0.05 | 0.03 | lasso | 2 | 0.02 | 9.3e-03 | 4.9 | -5.7 | 1.1e-08 | 0.56 | 0.19 | 0.48 | FALSE |
| 3 | GTEx | Thyroid | CHST10 | 0.05 | 0.05 | lasso | 5 | 0.03 | 2.6e-03 | -4.8 | -5.9 | 2.9e-09 | 0.60 | 0.38 | 0.42 | FALSE |
| 4 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | LONRF2 | 0.06 | 0.04 | blup | 69 | 0.04 | 3.4e-05 | 4.7 | -6.1 | 1.1e-09 | 0.68 | 0.55 | 0.43 | FALSE |