Best TWAS P=3.06e-09 · Best GWAS P=1.74e-10 conditioned to 1.87e-09
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TMEM54 | 0.05 | 0.00 | blup | 281 | 0.02 | 4.5e-03 | 0.95 | -5.8 | 6.7e-09 | -0.10 | 0.10 | 0.31 | TRUE |
| 2 | GTEx | Muscle Skeletal | FNDC5 | 0.15 | 0.16 | enet | 5 | 0.16 | 1.9e-15 | -5.35 | -5.4 | 8.0e-08 | -0.16 | 0.05 | 0.95 | FALSE |
| 3 | GTEx | Thyroid | BAI2 | 0.31 | 0.23 | lasso | 6 | 0.22 | 1.4e-16 | 5.54 | 5.6 | 2.3e-08 | -0.28 | 0.26 | 0.74 | TRUE |
| 4 | The Cancer Genome Atlas | Breast Invasive Carcinoma | S100PBP | 0.03 | 0.02 | blup | 46 | 0.02 | 6.6e-06 | -5.71 | 5.2 | 2.2e-07 | 0.14 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | S100PBP | 0.06 | 0.03 | blup | 48 | 0.06 | 6.8e-04 | -5.45 | 5.9 | 3.1e-09 | 0.12 | 0.01 | 0.81 | TRUE |
| 6 | The Cancer Genome Atlas | Glioblastoma Multiforme | S100PBP | 0.21 | 0.15 | lasso | 5 | 0.15 | 2.9e-05 | -5.35 | 5.3 | 9.0e-08 | 0.16 | 0.01 | 0.91 | FALSE |
| 7 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | S100PBP | 0.04 | 0.04 | lasso | 4 | 0.04 | 2.3e-05 | -5.74 | 5.7 | 9.6e-09 | 0.16 | 0.01 | 0.99 | FALSE |
| 8 | The Cancer Genome Atlas | Brain Lower Grade Glioma | S100PBP | 0.06 | 0.06 | blup | 47 | 0.05 | 5.2e-06 | -5.74 | 5.8 | 6.5e-09 | 0.14 | 0.00 | 1.00 | FALSE |