[Hub]/) : Traits : Arm fat mass (left) :

chr1:39,258,674-40,737,589

Best TWAS P=2.35e-11 · Best GWAS P=8.03e-12 conditioned to 0.00671

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex BMP8A 0.05 0.03 lasso 3 0.02 8.8e-04 5.6 5.8 7.8e-09 0.70 0.10 0.82 FALSE
2 GTEx Adrenal Gland PABPC4 0.20 0.09 lasso 8 0.06 3.0e-03 5.4 -6.7 2.3e-11 -0.76 0.04 0.86 TRUE
3 GTEx Adrenal Gland RP11-69E11.4 0.11 0.05 lasso 3 0.00 2.4e-01 4.5 5.3 9.6e-08 0.51 0.06 0.47 FALSE
4 GTEx Artery Tibial PABPC4 0.10 0.10 lasso 4 0.10 3.4e-08 5.4 -5.2 1.8e-07 -0.69 0.63 0.37 FALSE
5 GTEx Breast Mammary Tissue PABPC4 0.13 0.02 enet 14 0.04 3.4e-03 5.6 -5.5 4.8e-08 -0.68 0.10 0.75 FALSE
6 GTEx Breast Mammary Tissue (Female) PABPC4 0.10 0.00 enet 9 0.01 1.5e-01 6.3 -6.6 3.8e-11 -0.77 0.04 0.31 FALSE
7 GTEx Cells Transformed fibroblasts PABPC4 0.07 0.09 lasso 1 0.06 2.7e-05 5.4 -5.4 6.4e-08 -0.66 0.09 0.88 FALSE
8 GTEx Esophagus Mucosa PABPC4 0.06 0.06 lasso 3 0.08 7.3e-06 5.6 -5.5 4.0e-08 -0.71 0.33 0.61 FALSE
9 GTEx Nerve Tibial RP11-69E11.8 0.05 0.00 lasso 3 0.01 6.9e-02 5.4 -5.7 1.4e-08 -0.71 0.04 0.82 FALSE
10 GTEx Skin Not Sun Exposed Suprapubic PABPC4 0.12 0.10 lasso 3 0.05 1.0e-03 5.6 -5.6 1.8e-08 -0.69 0.18 0.62 FALSE
11 GTEx Skin Sun Exposed Lower leg PABPC4 0.11 0.09 lasso 7 0.08 2.7e-07 5.6 -5.4 8.5e-08 -0.74 0.09 0.91 FALSE
12 METSIM Adipose PABPC4 0.05 0.02 lasso 6 0.03 6.0e-05 5.6 -5.1 2.7e-07 -0.69 0.10 0.90 FALSE
13 NTR Blood PABPC4 0.01 0.00 blup 383 0.00 2.8e-02 5.4 -6.0 2.6e-09 -0.65 0.02 0.79 FALSE
14 The Cancer Genome Atlas Breast Invasive Carcinoma PABPC4 0.03 0.03 lasso 2 0.04 1.3e-08 5.4 -5.2 1.7e-07 -0.60 0.00 1.00 FALSE
15 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma BMP8A 0.04 0.03 blup 48 0.04 3.5e-05 3.9 5.6 1.6e-08 0.66 0.02 0.97 FALSE
16 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma PABPC4 0.03 0.01 enet 4 0.02 4.3e-03 5.4 -5.1 2.7e-07 -0.61 0.00 0.99 FALSE
17 The Cancer Genome Atlas Brain Lower Grade Glioma BMP8A 0.05 0.01 blup 48 0.04 6.8e-05 6.0 6.3 3.0e-10 0.66 0.00 0.98 FALSE
18 The Cancer Genome Atlas Lung Adenocarcinoma PABPC4 0.04 0.03 enet 8 0.04 4.5e-05 5.6 -5.4 8.3e-08 -0.61 0.00 1.00 FALSE
19 The Cancer Genome Atlas Thyroid Carcinoma PABPC4 0.09 0.07 enet 5 0.08 4.1e-08 5.4 -6.2 4.4e-10 -0.51 0.00 1.00 FALSE