Best TWAS P=2.27e-09 · Best GWAS P=6.32e-11 conditioned to 1.77e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | RIMKLA | 0.06 | 0.06 | bslmm | 341 | 0.05 | 1.3e-07 | -3.9 | 6.0 | 2.3e-09 | 0.16 | 0.97 | 0.00 | TRUE |
| 2 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | RIMKLA | 0.03 | 0.02 | blup | 53 | 0.01 | 2.8e-02 | 4.4 | 5.4 | 8.1e-08 | 0.23 | 0.00 | 0.55 | FALSE |