Best TWAS P=1.23e-12 · Best GWAS P=1.51e-15 conditioned to 4.6e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Whole Blood | RP1-18D14.7 | 0.15 | 0.13 | enet | 17 | 0.13 | 7.7e-12 | 7.0 | -5.2 | 1.6e-07 | 0.03 | 0.01 | 0.99 | FALSE |
| 2 | METSIM | Adipose | AGBL4 | 0.02 | 0.02 | lasso | 5 | 0.02 | 1.3e-03 | 7.0 | -7.1 | 1.2e-12 | -0.85 | 0.16 | 0.82 | TRUE |
| 3 | YFS | Blood | TAL1 | 0.03 | 0.02 | bslmm | 402 | 0.02 | 2.6e-06 | 6.9 | -6.8 | 1.2e-11 | 0.03 | 0.01 | 0.99 | TRUE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | TAL1 | 0.03 | 0.02 | blup | 75 | 0.02 | 9.2e-03 | 5.9 | 5.5 | 4.3e-08 | -0.01 | 0.02 | 0.81 | FALSE |