[Hub]/) : Traits : Arm fat mass (left) : ← →

chr6:41,042,590-42,907,327

Best TWAS P=1.07e-10 · Best GWAS P=1.39e-10 conditioned to 0.00649

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells Transformed fibroblasts MED20 0.11 0.05 lasso 4 0.08 9.4e-07 -5.5 5.9 4.6e-09 0.46 0.52 0.46 FALSE
2 GTEx Colon Transverse MED20 0.17 0.01 enet 10 0.06 6.0e-04 5.0 5.8 5.8e-09 0.69 0.17 0.62 FALSE
3 GTEx Lung BYSL 0.08 0.03 lasso 4 0.02 4.9e-03 5.8 -5.5 4.2e-08 -0.80 0.12 0.79 FALSE
4 GTEx Testis MED20 0.13 0.03 lasso 6 0.00 2.0e-01 -5.0 5.2 2.4e-07 0.46 0.15 0.19 FALSE
5 GTEx Thyroid FRS3 0.20 0.16 lasso 4 0.16 5.2e-12 5.7 5.4 7.1e-08 0.67 0.08 0.92 FALSE
6 The Cancer Genome Atlas Colon Adenocarcinoma MED20 0.05 0.00 blup 50 0.04 2.8e-03 4.8 6.5 1.1e-10 0.70 0.06 0.32 TRUE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma MED20 0.04 0.03 lasso 3 0.04 7.3e-05 -5.5 5.5 3.4e-08 0.45 0.30 0.48 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma MED20 0.09 0.08 enet 12 0.09 5.5e-10 5.1 5.4 5.5e-08 0.62 0.85 0.15 FALSE
9 The Cancer Genome Atlas Liver Hepatocellular Carcinoma MED20 0.09 0.07 lasso 5 0.07 3.4e-04 -5.0 5.7 1.4e-08 0.51 0.16 0.60 FALSE
10 The Cancer Genome Atlas Pheochromocytoma and Paraganglioma UBR2 0.10 0.01 blup 77 0.04 9.1e-03 4.4 -5.7 1.5e-08 0.01 0.01 0.58 TRUE
11 The Cancer Genome Atlas Prostate Adenocarcinoma MED20 0.04 0.06 enet 6 0.05 2.6e-06 4.8 5.5 5.0e-08 0.58 0.78 0.16 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma MED20 0.03 0.05 lasso 2 0.04 1.2e-03 -5.5 5.5 3.1e-08 0.44 0.09 0.23 FALSE