[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr10:76,459,669-80,383,574

Best TWAS P=1.13e-15 · Best GWAS P=5.63e-15 conditioned to 0.812

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
15	GTEx	Esophagus Muscularis	C10orf11	0.45	0.39	enet	42	0.38	5.1e-24	6.8	-8.0	1.1e-15	-0.84	0.25	0.75	TRUE
13	GTEx	Esophagus Gastroesophageal Junction	DLG5	0.27	0.03	enet	13	0.06	3.9e-03	-6.3	-5.7	1.0e-08	-0.06	0.00	0.98	TRUE
29	ROSMAP	Brain Pre-frontal Cortex	ZNF503	0.05	0.04	bslmm	342	0.04	2.2e-06	6.1	5.5	2.9e-08	0.15	0.96	0.01	TRUE
4	GTEx	Adipose Visceral Omentum	C10orf11	0.40	0.32	enet	11	0.27	2.2e-14	6.8	-7.7	1.6e-14	-0.89	0.03	0.97	FALSE
26	GTEx	Thyroid	C10orf11	0.38	0.21	lasso	9	0.25	6.7e-19	6.3	-7.6	4.1e-14	-0.80	0.14	0.86	FALSE
17	GTEx	Lung	C10orf11	0.30	0.26	lasso	5	0.24	2.0e-18	6.8	-7.4	1.0e-13	-0.87	0.06	0.94	FALSE
2	GTEx	Adipose Subcutaneous	C10orf11	0.24	0.21	lasso	9	0.20	3.3e-16	6.8	-7.4	1.2e-13	-0.87	0.06	0.94	FALSE
28	METSIM	Adipose	C10orf11	0.11	0.10	enet	14	0.10	1.1e-14	6.3	-6.6	3.1e-11	-0.78	0.52	0.48	FALSE
5	GTEx	Adrenal Gland	C10orf11	0.24	0.22	enet	21	0.18	5.8e-07	6.8	-6.6	4.0e-11	-0.83	0.02	0.98	FALSE
30	ROSMAP	Brain Pre-frontal Cortex	ZNF503-AS2	0.07	0.06	lasso	2	0.06	2.2e-08	6.1	6.3	2.1e-10	0.29	0.99	0.01	FALSE
19	GTEx	Nerve Tibial	DLG5	0.51	0.44	lasso	6	0.50	1.4e-39	-5.2	-5.6	1.9e-08	0.01	0.45	0.55	FALSE
7	GTEx	Artery Aorta	DLG5	0.26	0.19	enet	10	0.22	2.6e-12	-4.9	-5.5	3.4e-08	0.01	0.33	0.67	FALSE
21	GTEx	Ovary	DLG5	0.62	0.38	lasso	6	0.40	5.3e-11	-5.1	-5.4	5.3e-08	0.01	0.51	0.48	FALSE
10	GTEx	Cells Transformed fibroblasts	DLG5	0.25	0.18	lasso	11	0.16	2.0e-12	-5.1	-5.4	5.4e-08	0.02	0.17	0.83	FALSE
1	CommonMind	Brain Pre-frontal Cortex	ZNF503	0.08	0.00	blup	366	0.03	2.5e-04	6.6	5.4	5.6e-08	0.19	0.36	0.03	FALSE
20	GTEx	Nerve Tibial	RP13-39P12.3	0.31	0.25	lasso	7	0.36	1.3e-26	-5.1	-5.4	7.0e-08	0.00	0.24	0.76	FALSE
24	GTEx	Pituitary	RP13-39P12.3	0.38	0.22	lasso	11	0.17	3.8e-05	-5.1	-5.4	7.0e-08	0.02	0.03	0.93	FALSE
22	GTEx	Ovary	RP13-39P12.3	0.42	0.29	lasso	5	0.33	7.5e-09	-5.1	-5.4	7.4e-08	0.01	0.43	0.45	FALSE
23	GTEx	Pituitary	DLG5	0.45	0.36	lasso	11	0.31	1.9e-08	-5.1	-5.3	8.9e-08	0.02	0.06	0.93	FALSE
6	GTEx	Adrenal Gland	DLG5	0.22	0.14	lasso	6	0.11	8.5e-05	-5.1	-5.3	9.0e-08	0.02	0.28	0.54	FALSE
11	GTEx	Cells Transformed fibroblasts	RP13-39P12.3	0.19	0.13	lasso	7	0.15	4.5e-11	-5.1	-5.3	1.1e-07	0.00	0.33	0.66	FALSE
9	GTEx	Artery Coronary	DLG5	0.33	0.25	lasso	4	0.27	1.4e-09	-5.3	-5.3	1.4e-07	0.00	0.22	0.77	FALSE
12	GTEx	Colon Transverse	DLG5	0.23	0.17	lasso	8	0.19	1.4e-09	-5.3	-5.3	1.4e-07	0.00	0.40	0.60	FALSE
18	GTEx	Lung	DLG5	0.41	0.38	lasso	8	0.37	7.9e-30	-5.1	-5.2	1.5e-07	0.01	0.54	0.46	FALSE
3	GTEx	Adipose Subcutaneous	DLG5	0.39	0.40	lasso	12	0.43	1.9e-38	-5.2	-5.2	1.7e-07	0.01	0.44	0.56	FALSE
8	GTEx	Artery Aorta	RP13-39P12.3	0.14	0.13	enet	9	0.12	2.2e-07	-4.9	-5.2	1.7e-07	0.03	0.07	0.92	FALSE
25	GTEx	Spleen	DLG5	0.51	0.46	lasso	4	0.44	1.1e-12	-5.2	-5.2	2.2e-07	0.01	0.40	0.60	FALSE
14	GTEx	Esophagus Mucosa	DLG5	0.21	0.16	lasso	5	0.18	5.2e-12	-5.2	-5.2	2.4e-07	0.00	0.48	0.52	FALSE
27	GTEx	Thyroid	RP13-39P12.3	0.28	0.30	lasso	8	0.29	3.3e-22	-5.1	-5.1	2.7e-07	0.02	0.57	0.43	FALSE
16	GTEx	Heart Atrial Appendage	DLG5	0.32	0.23	lasso	4	0.24	3.9e-11	-5.0	-5.1	2.8e-07	0.02	0.48	0.52	FALSE