[Hub]/) : Traits : Arm fat-free mass (left) :

chr10:76,459,669-80,383,574

Best TWAS P=1.13e-15 · Best GWAS P=5.63e-15 conditioned to 0.812

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ZNF503 0.08 0.00 blup 366 0.03 2.5e-04 6.6 5.4 5.6e-08 0.19 0.36 0.03 FALSE
2 GTEx Adipose Subcutaneous C10orf11 0.24 0.21 lasso 9 0.20 3.3e-16 6.8 -7.4 1.2e-13 -0.87 0.06 0.94 FALSE
3 GTEx Adipose Subcutaneous DLG5 0.39 0.40 lasso 12 0.43 1.9e-38 -5.2 -5.2 1.7e-07 0.01 0.44 0.56 FALSE
4 GTEx Adipose Visceral Omentum C10orf11 0.40 0.32 enet 11 0.27 2.2e-14 6.8 -7.7 1.6e-14 -0.89 0.03 0.97 FALSE
5 GTEx Adrenal Gland C10orf11 0.24 0.22 enet 21 0.18 5.8e-07 6.8 -6.6 4.0e-11 -0.83 0.02 0.98 FALSE
6 GTEx Adrenal Gland DLG5 0.22 0.14 lasso 6 0.11 8.5e-05 -5.1 -5.3 9.0e-08 0.02 0.28 0.54 FALSE
7 GTEx Artery Aorta DLG5 0.26 0.19 enet 10 0.22 2.6e-12 -4.9 -5.5 3.4e-08 0.01 0.33 0.67 FALSE
8 GTEx Artery Aorta RP13-39P12.3 0.14 0.13 enet 9 0.12 2.2e-07 -4.9 -5.2 1.7e-07 0.03 0.07 0.92 FALSE
9 GTEx Artery Coronary DLG5 0.33 0.25 lasso 4 0.27 1.4e-09 -5.3 -5.3 1.4e-07 0.00 0.22 0.77 FALSE
10 GTEx Cells Transformed fibroblasts DLG5 0.25 0.18 lasso 11 0.16 2.0e-12 -5.1 -5.4 5.4e-08 0.02 0.17 0.83 FALSE
11 GTEx Cells Transformed fibroblasts RP13-39P12.3 0.19 0.13 lasso 7 0.15 4.5e-11 -5.1 -5.3 1.1e-07 0.00 0.33 0.66 FALSE
12 GTEx Colon Transverse DLG5 0.23 0.17 lasso 8 0.19 1.4e-09 -5.3 -5.3 1.4e-07 0.00 0.40 0.60 FALSE
13 GTEx Esophagus Gastroesophageal Junction DLG5 0.27 0.03 enet 13 0.06 3.9e-03 -6.3 -5.7 1.0e-08 -0.06 0.00 0.98 TRUE
14 GTEx Esophagus Mucosa DLG5 0.21 0.16 lasso 5 0.18 5.2e-12 -5.2 -5.2 2.4e-07 0.00 0.48 0.52 FALSE
15 GTEx Esophagus Muscularis C10orf11 0.45 0.39 enet 42 0.38 5.1e-24 6.8 -8.0 1.1e-15 -0.84 0.25 0.75 TRUE
16 GTEx Heart Atrial Appendage DLG5 0.32 0.23 lasso 4 0.24 3.9e-11 -5.0 -5.1 2.8e-07 0.02 0.48 0.52 FALSE
17 GTEx Lung C10orf11 0.30 0.26 lasso 5 0.24 2.0e-18 6.8 -7.4 1.0e-13 -0.87 0.06 0.94 FALSE
18 GTEx Lung DLG5 0.41 0.38 lasso 8 0.37 7.9e-30 -5.1 -5.2 1.5e-07 0.01 0.54 0.46 FALSE
19 GTEx Nerve Tibial DLG5 0.51 0.44 lasso 6 0.50 1.4e-39 -5.2 -5.6 1.9e-08 0.01 0.45 0.55 FALSE
20 GTEx Nerve Tibial RP13-39P12.3 0.31 0.25 lasso 7 0.36 1.3e-26 -5.1 -5.4 7.0e-08 0.00 0.24 0.76 FALSE
21 GTEx Ovary DLG5 0.62 0.38 lasso 6 0.40 5.3e-11 -5.1 -5.4 5.3e-08 0.01 0.51 0.48 FALSE
22 GTEx Ovary RP13-39P12.3 0.42 0.29 lasso 5 0.33 7.5e-09 -5.1 -5.4 7.4e-08 0.01 0.43 0.45 FALSE
23 GTEx Pituitary DLG5 0.45 0.36 lasso 11 0.31 1.9e-08 -5.1 -5.3 8.9e-08 0.02 0.06 0.93 FALSE
24 GTEx Pituitary RP13-39P12.3 0.38 0.22 lasso 11 0.17 3.8e-05 -5.1 -5.4 7.0e-08 0.02 0.03 0.93 FALSE
25 GTEx Spleen DLG5 0.51 0.46 lasso 4 0.44 1.1e-12 -5.2 -5.2 2.2e-07 0.01 0.40 0.60 FALSE
26 GTEx Thyroid C10orf11 0.38 0.21 lasso 9 0.25 6.7e-19 6.3 -7.6 4.1e-14 -0.80 0.14 0.86 FALSE
27 GTEx Thyroid RP13-39P12.3 0.28 0.30 lasso 8 0.29 3.3e-22 -5.1 -5.1 2.7e-07 0.02 0.57 0.43 FALSE
28 METSIM Adipose C10orf11 0.11 0.10 enet 14 0.10 1.1e-14 6.3 -6.6 3.1e-11 -0.78 0.52 0.48 FALSE
29 ROSMAP Brain Pre-frontal Cortex ZNF503 0.05 0.04 bslmm 342 0.04 2.2e-06 6.1 5.5 2.9e-08 0.15 0.96 0.01 TRUE
30 ROSMAP Brain Pre-frontal Cortex ZNF503-AS2 0.07 0.06 lasso 2 0.06 2.2e-08 6.1 6.3 2.1e-10 0.29 0.99 0.01 FALSE