TWAS
hub
About
Usage
Models
Genes
Traits
[Hub]/) :
Traits
:
Arm fat-free mass (left)
:
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chr10:80,443,273-81,901,722
Best TWAS P=7.46e-13 · Best GWAS P=2.25e-10 conditioned to 0.223
80.4M
80.6M
80.8M
81M
81.2M
81.4M
81.6M
81.8M
0
2
4
6
8
10
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Adipose Subcutaneous
ZCCHC24
0.12
0.01
lasso
6
0.03
3.4e-03
5.64
7.2
7.5e-13
0.78
0.02
0.94
TRUE
3
The Cancer Genome Atlas
Bladder Urothelial Carcinoma
ZCCHC24
0.06
0.00
blup
89
0.01
6.2e-02
3.92
7.1
1.2e-12
0.41
0.01
0.12
FALSE
4
The Cancer Genome Atlas
Kidney Renal Clear Cell Carcinoma
ZCCHC24
0.07
0.05
enet
9
0.04
6.7e-05
6.17
6.3
2.3e-10
0.95
0.00
1.00
FALSE
2
GTEx
Skin Sun Exposed Lower leg
ZCCHC24
0.09
0.00
enet
18
0.00
2.3e-01
-0.74
6.3
3.9e-10
0.43
0.03
0.60
FALSE