Best TWAS P=1.17e-08 · Best GWAS P=6.63e-09 conditioned to 0.000285
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Adipose Subcutaneous | PTPRJ | 0.05 | 0.05 | lasso | 2 | 0.04 | 3.9e-04 | 5.8 | 5.5 | 2.8e-08 | 0.99 | 0.01 | 0.97 | FALSE |
| 2 | GTEx | Prostate | PSMC3 | 0.21 | 0.10 | lasso | 6 | 0.20 | 7.9e-06 | 4.3 | -5.2 | 2.3e-07 | -0.22 | 0.05 | 0.29 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | CELF1 | 0.03 | 0.01 | bslmm | 289 | 0.01 | 2.9e-02 | 4.7 | 5.7 | 1.2e-08 | 0.45 | 0.04 | 0.78 | TRUE |