TWAS hub - PSMC3

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	CommonMind	Brain Pre-frontal Cortex	0.0440	0.0270	4.2e-03	-0.002	0.005	0.007	0.006	-0.001	6.1e-01	6.5e-02	3.8e-02	5.1e-02	4.7e-01
2	GTEx	Breast Mammary Tissue (Female)	0.0240	0.0345	2.8e-01	0.007	NA	-0.010	NA	0.039	2.0e-01	NA	1.0e+00	NA	2.5e-02
3	GTEx	Cells Transformed fibroblasts	0.0650	0.0350	4.0e-03	-0.001	NA	0.015	NA	0.003	4.1e-01	NA	2.3e-02	NA	1.6e-01
4	GTEx	Liver	0.1530	0.0780	4.6e-03	0.089	NA	0.014	NA	0.068	1.8e-03	NA	1.3e-01	NA	5.9e-03
5	GTEx	Lung	0.0719	0.0359	3.2e-03	0.017	NA	0.024	NA	0.027	1.6e-02	NA	5.7e-03	NA	3.6e-03
6	GTEx	Prostate	0.2070	0.0900	1.8e-03	0.105	NA	0.190	NA	0.203	1.4e-03	NA	1.6e-05	NA	7.9e-06
7	GTEx	Skin Sun Exposed Lower leg	0.1950	0.0560	4.2e-08	0.046	NA	0.089	NA	0.100	9.7e-05	NA	7.8e-08	NA	1.2e-08
8	METSIM	Adipose	0.0571	0.0283	7.9e-05	0.026	0.035	0.037	0.035	0.030	6.4e-05	4.9e-06	2.3e-06	4.1e-06	2.2e-05
9	ROSMAP	Brain Pre-frontal Cortex	0.1487	0.0551	4.5e-10	0.078	0.098	0.100	0.102	0.100	3.0e-10	1.3e-12	7.7e-13	5.1e-13	7.6e-13
10	YFS	Blood	0.0151	0.0076	1.9e-04	0.010	0.013	0.008	0.012	0.008	1.9e-04	2.8e-05	7.6e-04	5.6e-05	1.1e-03
11	TCGA	Colon Adenocarcinoma	0.0910	0.0520	5.5e-04	0.051	0.047	0.043	NA	0.041	6.7e-04	1.0e-03	1.6e-03	NA	2.0e-03
12	TCGA	Head and Neck Squamous Cell Carcinoma	0.0473	0.0331	3.5e-03	0.010	0.023	0.014	NA	0.024	2.2e-02	1.2e-03	9.5e-03	NA	9.4e-04
13	TCGA	Kidney Renal Clear Cell Carcinoma	0.0487	0.0273	3.8e-05	0.036	0.038	0.039	NA	0.048	5.9e-05	3.6e-05	2.8e-05	NA	3.8e-06
14	TCGA	Kidney Renal Papillary Cell Carcinoma	0.0720	0.0390	7.4e-04	0.069	0.055	0.065	NA	0.062	8.7e-05	4.2e-04	1.4e-04	NA	1.9e-04
15	TCGA	Brain Lower Grade Glioma	0.1010	0.0446	4.0e-09	0.048	0.078	0.066	NA	0.074	3.5e-06	3.7e-09	5.1e-08	NA	9.2e-09
16	TCGA	Liver Hepatocellular Carcinoma	0.0930	0.0510	1.9e-04	0.073	0.060	0.055	NA	0.050	2.6e-04	8.7e-04	1.3e-03	NA	2.2e-03
17	TCGA	Prostate Adenocarcinoma	0.0218	0.0140	9.3e-03	0.021	0.017	0.001	NA	0.015	2.3e-03	5.7e-03	2.4e-01	NA	1.0e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17
Arm fat percentage (left)	16.3	65.2	125.4	5.0	4.2	10.2	8.0	2.4	3.1	7.1	8.7	7.2	10.4	9.2	4.4	8.3	11.1	9.7	11.2	9.1
HDL Cholesterol	15.7	26.3	50.9	-1.9	-6.4	-7.1	-4.8	-1.6	-3.6	-5.1	-6.4	-4.4	-6.5	-0.3	-3.0	-5.2	-5.2	-5.2	-6.6	-7.1
Arm fat percentage (right)	15.2	60.0	112.4	4.9	4.1	9.8	7.5	2.6	3.0	6.9	8.4	7.0	9.9	8.8	4.2	7.9	10.6	9.4	10.6	8.6
Leg fat percentage (left)	14.6	52.7	88.9	4.7	5.5	9.0	5.7	4.4	4.4	7.5	8.0	8.0	9.4	6.6	3.2	7.2	8.8	9.4	9.0	8.1
Loneliness, isolation	14.0	19.3	43.0	-4.1	-1.9	-4.3	-3.4	-1.3	-2.1	-4.5	-5.4	-3.2	-2.9	-5.6	-6.6	-5.4	-6.0	-3.5	-5.1	-4.9
Body fat percentage	13.8	54.4	97.0	4.1	4.2	9.3	6.6	3.3	3.5	6.9	7.7	7.3	9.8	8.1	3.2	7.4	9.8	9.5	9.8	8.1
Leg fat percentage (right)	13.5	49.1	83.0	4.5	5.4	8.6	5.6	4.5	4.5	7.3	7.6	7.9	9.1	6.4	3.3	6.9	8.4	9.1	8.5	7.7
Trunk fat percentage	12.0	48.2	92.2	3.7	3.1	8.8	6.7	2.6	2.8	6.2	7.0	6.5	9.4	8.6	3.0	6.9	9.6	8.8	9.4	7.3
Suffer from ‘nerves’	11.2	17.6	39.3	-3.6	-1.1	-5.1	-5.0	0.5	-0.2	-2.6	-5.0	-2.0	-3.4	-5.5	-5.4	-4.3	-6.3	-3.3	-5.9	-4.8
Blood White Count	11.0	81.4	141.6	6.8	8.7	8.8	7.7	4.8	6.1	10.1	11.1	8.3	7.6	5.6	10.9	10.8	10.6	8.5	10.9	11.9
Body Mass Index (BMI) (2010)	10.5	14.3	29.2	2.0	1.2	4.5	4.2	0.8	1.8	3.3	3.9	3.3	5.1	5.0	1.8	4.1	5.4	4.1	5.2	3.9
Standing height	10.3	102.5	153.8	-8.3	-10.2	-11.0	-8.9	-7.4	-9.4	-11.1	-12.4	-11.0	-10.7	-5.4	-10.1	-10.4	-10.4	-10.4	-10.6	-12.1
BMI	10.0	57.8	123.2	4.7	4.0	9.3	7.4	1.3	2.0	6.2	8.8	6.8	9.6	8.2	3.9	7.7	10.7	9.1	11.1	8.9
Body mass index (BMI)	9.6	41.1	83.9	4.1	3.3	8.1	6.2	1.6	2.0	5.5	7.4	5.6	7.9	7.1	3.4	6.7	9.0	7.6	9.2	7.4
Forced vital capacity (FVC), Best measure	9.4	34.4	59.3	-3.6	-5.1	-7.2	-5.6	-3.9	-5.2	-5.8	-6.0	-6.7	-7.7	-4.2	-3.4	-5.8	-6.6	-7.0	-6.7	-6.6
Blood Platelet Count	9.3	108.3	185.0	-9.1	-8.6	-11.7	-7.8	-10.6	-11.0	-12.0	-11.0	-13.1	-13.5	-8.2	-2.7	-9.7	-9.9	-13.6	-9.4	-9.6
Sitting height	8.7	61.9	83.4	-5.8	-4.9	-8.0	-9.0	-5.6	-7.3	-8.1	-8.4	-8.1	-9.0	-7.8	-8.8	-8.2	-9.1	-7.6	-8.1	-8.3
Height	8.4	161.0	234.1	-10.6	-13.8	-14.3	-10.9	-10.0	-12.1	-14.0	-15.3	-14.0	-13.5	-5.8	-12.2	-12.7	-12.4	-12.7	-12.9	-15.2
Breastfed as a baby	8.2	10.2	17.3	-1.6	-3.2	-3.8	-2.7	-2.4	-2.7	-3.3	-3.1	-3.7	-3.9	-2.0	-2.1	-3.0	-3.5	-4.2	-3.7	-3.9
Hand grip strength (left)	7.8	20.6	40.1	-2.7	-1.9	-4.9	-5.6	-2.5	-3.2	-3.8	-4.3	-5.4	-6.3	-5.3	-2.5	-4.0	-5.6	-6.0	-5.3	-4.4
Alcohol intake frequency.	7.8	18.2	32.4	3.1	2.0	4.7	5.1	2.0	2.1	3.8	4.2	4.1	5.1	5.6	2.3	4.2	5.7	5.5	5.4	4.3
Arm fat mass (right)	7.6	31.2	68.6	3.3	2.1	7.3	5.5	0.8	0.8	4.4	6.0	4.5	7.2	7.0	2.1	5.7	8.2	6.8	8.3	6.1
Arm fat mass (left)	7.6	31.2	69.2	3.2	1.9	7.2	5.5	0.6	0.8	4.3	5.9	4.4	7.1	7.2	2.0	5.7	8.3	6.8	8.3	6.0
Myopia	7.5	10.9	21.4	-2.7	-2.8	-3.8	-3.9	-0.7	-1.8	-3.0	-3.9	-2.3	-3.6	-2.2	-2.8	-3.8	-4.4	-2.9	-4.6	-4.3
Townsend deprivation index at recruitment	7.3	10.2	22.6	-2.6	-1.8	-3.2	-3.1	-1.0	-2.3	-3.2	-3.5	-2.5	-2.4	-3.7	-4.8	-3.6	-4.3	-2.5	-3.8	-3.8
Alcohol drinker status: Never	7.3	8.7	12.7	2.5	1.6	3.0	3.0	1.9	2.4	2.8	3.0	3.5	3.3	3.4	2.9	2.7	3.6	3.5	3.2	3.0
Verbal and Numeric Reasoning (VNR)	7.2	17.3	33.2	-4.9	-4.1	-5.5	-2.9	-0.9	-1.8	-4.1	-5.8	-2.9	-3.8	-2.3	-3.1	-5.0	-5.0	-3.9	-5.5	-5.4
Comparative body size at age 10	7.2	19.8	65.3	2.0	1.5	5.2	5.0	-2.9	-1.3	1.9	4.9	1.8	4.5	4.7	2.8	4.4	7.2	4.1	8.1	5.8
Leg fat mass (left)	7.0	27.2	57.3	2.9	2.7	6.7	4.6	1.3	1.2	4.5	5.8	4.8	6.7	5.8	1.7	5.3	7.3	6.8	7.6	5.9
Forced vital capacity (FVC)	6.8	26.0	46.4	-3.0	-4.5	-6.3	-4.9	-3.3	-4.6	-5.0	-5.4	-5.8	-6.8	-3.4	-3.4	-5.0	-5.6	-6.0	-5.8	-5.8
Leg fat mass (right)	6.8	26.5	54.5	2.9	2.8	6.6	4.6	1.5	1.4	4.5	5.7	4.8	6.7	5.6	1.6	5.2	7.1	6.7	7.4	5.8
Whole body fat mass	6.7	28.0	60.1	2.7	2.0	6.9	4.8	1.1	1.0	4.3	5.4	4.6	7.2	6.7	1.3	5.3	7.7	6.9	7.8	5.6
Trunk fat mass	6.3	26.9	58.4	2.5	1.4	6.8	4.9	0.9	0.8	4.0	5.0	4.3	7.1	7.2	1.2	5.1	7.6	6.7	7.6	5.3
Fluid intelligence score	6.3	13.1	27.5	-4.0	-2.6	-4.5	-3.0	0.5	-1.2	-2.8	-4.9	-1.6	-3.1	-2.5	-3.9	-4.7	-4.9	-2.6	-5.2	-4.9
Seen doctor (GP) for nerves, anxiety, tension or depression	6.2	9.5	16.3	-3.3	-1.9	-3.1	-2.6	-2.0	-2.3	-3.3	-3.8	-2.3	-2.1	-3.6	-4.0	-3.9	-4.0	-2.0	-3.3	-3.3
Comparative height size at age 10	6.1	33.5	47.6	-5.2	-6.7	-6.3	-5.0	-5.5	-6.7	-6.5	-6.8	-6.9	-6.6	-1.9	-5.0	-5.2	-4.7	-5.9	-4.9	-6.4
Forced expiratory volume in 1-second (FEV1), predicted	6.1	12.6	20.4	-2.2	-3.7	-4.4	-3.4	-2.4	-3.2	-3.4	-3.7	-4.1	-4.5	-1.9	-3.1	-2.7	-3.7	-4.3	-4.0	-4.3
Average weekly beer plus cider intake	6.1	8.9	19.6	-3.2	-1.0	-3.3	-4.4	-1.7	-2.5	-2.6	-2.7	-2.2	-3.3	-3.7	-2.8	-3.5	-3.7	-2.2	-3.2	-2.8
Hearing aid user	6.0	6.7	15.1	2.1	2.7	3.1	1.1	2.2	1.6	2.8	3.1	3.1	2.9	1.3	0.8	2.6	2.6	3.9	2.9	3.1
Systolic Blood Pressure	5.9	29.5	187.7	-5.5	5.0	-1.6	-4.4	-3.4	-3.8	-3.8	-4.0	-3.6	-3.0	-13.7	-8.3	-5.0	-6.8	-2.7	-2.9	-1.2
Neuroticism score	5.8	12.1	37.3	-2.1	0.7	-2.6	-3.4	0.4	-0.9	-2.7	-4.1	-1.9	-1.9	-6.1	-5.8	-4.3	-5.3	-2.2	-4.2	-3.3
Birth weight	5.8	12.7	18.3	-1.6	-2.7	-3.3	-3.8	-2.3	-3.1	-3.9	-4.0	-4.1	-4.2	-2.6	-3.1	-4.1	-4.0	-4.3	-3.9	-4.2
Ever used hormone-replacement therapy (HRT)	5.7	7.3	14.9	1.7	0.9	2.4	3.9	-0.1	1.1	2.3	3.4	1.5	2.3	2.8	3.5	3.7	3.8	1.7	3.6	3.2
Lung cancer (father)	5.7	6.6	14.6	-1.1	-1.3	-2.3	-3.5	0.8	-1.5	-1.9	-3.2	-1.5	-2.5	-1.8	-2.9	-3.5	-3.7	-1.8	-3.8	-3.5
Waist circumference	5.6	20.3	48.4	2.3	0.2	5.3	5.0	0.6	1.0	3.1	4.0	3.8	6.1	7.0	1.3	4.6	6.9	5.4	6.5	4.3
Trunk fat-free mass	5.6	32.0	51.6	-3.6	-6.3	-5.7	-4.7	-5.6	-7.2	-6.8	-5.9	-6.7	-6.3	-2.4	-5.7	-5.4	-4.8	-5.9	-4.7	-6.3
Forced expiratory volume in 1-second (FEV1), Best measure	5.6	17.8	34.5	-2.2	-4.0	-5.6	-3.8	-2.6	-3.3	-4.0	-4.1	-4.9	-5.9	-2.8	-1.7	-3.8	-4.7	-5.6	-5.1	-4.9
Severe depression (siblings)	5.5	6.2	10.6	-1.8	-2.2	-2.4	-3.2	-1.3	-1.7	-2.2	-2.2	-2.4	-2.6	-2.0	-2.1	-2.6	-3.1	-2.9	-3.3	-3.1
Current tobacco smoking	5.5	9.1	17.2	-2.8	-1.3	-3.5	-3.5	-0.3	-2.0	-2.5	-4.0	-2.1	-3.1	-3.1	-3.4	-3.5	-4.2	-2.0	-3.8	-3.4
Trunk predicted mass	5.5	31.3	51.1	-3.6	-6.3	-5.7	-4.6	-5.6	-7.2	-6.8	-5.8	-6.7	-6.2	-2.3	-5.7	-5.4	-4.7	-5.8	-4.5	-6.2
Smoking status: Current	5.5	8.8	17.1	-2.9	-1.2	-3.4	-3.6	0.0	-1.8	-2.3	-4.0	-1.8	-2.9	-3.0	-3.4	-3.5	-4.1	-1.8	-3.8	-3.4
Neuroticism	5.4	13.1	36.0	-3.0	0.1	-2.6	-3.1	-0.4	-1.2	-3.0	-4.8	-2.3	-1.8	-6.0	-5.7	-4.6	-5.3	-2.6	-4.2	-3.5
Eye problems/disorders: Glaucoma	5.3	6.3	15.7	-1.7	-3.6	-3.2	-1.1	-0.7	-1.6	-2.4	-3.3	-1.7	-1.9	0.7	-2.8	-2.9	-2.5	-2.0	-3.3	-4.0
Frequency of tiredness / lethargy in last 2 weeks	5.2	8.4	20.5	-4.4	-1.8	-2.9	-0.9	-1.8	-1.6	-3.2	-3.7	-2.8	-1.4	-3.2	-4.5	-2.7	-3.2	-2.6	-2.6	-3.0
Intelligence (Savage-Jansen 2018)	5.0	15.3	30.2	-4.0	-3.7	-5.4	-3.3	-0.3	-1.0	-3.5	-5.4	-2.2	-3.6	-2.2	-3.1	-4.7	-4.9	-3.6	-5.5	-5.2
Hip circumference	5.0	21.6	49.9	2.2	2.0	5.5	5.2	0.6	0.9	3.6	5.1	4.0	6.1	5.1	1.4	4.9	6.8	5.7	7.1	5.3
Guilty feelings	5.0	7.6	26.4	-3.0	0.4	-2.3	-2.8	-1.5	-2.5	-2.9	-2.9	-2.3	-2.6	-5.1	-3.1	-3.1	-3.5	-2.0	-2.3	-1.7
Depressed Affect (Nagel 2018)	4.8	10.1	40.2	-2.2	2.0	-1.6	-3.2	0.9	0.2	-1.6	-3.8	-0.5	-0.7	-6.3	-6.0	-3.8	-4.8	-0.9	-3.4	-2.4
Medication: Metformin	4.8	6.8	19.5	0.7	0.3	2.6	1.8	0.7	0.5	1.9	2.2	2.7	3.6	4.4	0.6	2.5	4.0	3.6	3.8	2.5
Ever had hysterectomy (womb removed)	4.7	5.3	9.5	1.7	1.4	2.1	3.1	1.1	2.4	2.5	2.5	2.6	2.5	2.0	2.0	2.8	2.7	2.2	2.4	2.5
Angina (self-reported)	4.7	6.1	12.1	1.2	3.0	2.3	1.8	2.2	3.0	2.9	2.5	3.4	3.2	0.7	-0.1	2.3	2.0	3.5	2.4	2.6
Eye problems/disorders: Diabetes related eye disease	4.6	5.1	10.6	2.3	0.8	3.2	2.6	-0.2	0.7	1.8	2.3	1.1	2.7	2.9	1.1	2.5	3.3	2.1	3.2	2.3
Angina	4.6	6.1	12.5	1.2	3.0	2.4	1.8	2.3	2.9	2.9	2.5	3.4	3.2	0.7	-0.2	2.2	2.0	3.5	2.3	2.6
Hand grip strength (right)	4.6	12.5	21.9	-2.6	-0.9	-3.4	-4.7	-1.7	-2.5	-2.7	-3.5	-4.0	-4.7	-4.6	-2.7	-3.3	-4.5	-4.3	-4.0	-3.3
Miserableness	4.6	7.9	37.6	-1.6	2.2	-1.4	-2.8	0.9	1.2	-1.2	-2.9	-0.7	-0.7	-6.1	-4.8	-2.9	-4.4	-1.2	-3.2	-1.9
Neuroticism (2016)	4.5	6.5	26.0	-2.2	1.0	-2.0	-1.8	0.5	-0.1	-1.5	-2.7	-1.0	-1.6	-5.1	-3.6	-3.0	-4.2	-1.6	-3.2	-2.2
Medication: Levothyroxine sodium	4.5	7.6	15.2	2.3	2.1	2.8	2.4	0.5	1.3	2.7	3.4	2.1	2.1	2.1	2.8	3.7	3.8	2.5	3.9	3.7
Worry (Nagel 2018)	4.4	9.4	25.9	-1.4	0.9	-2.0	-4.0	1.8	1.0	-1.1	-3.3	-0.4	-1.2	-5.1	-5.0	-3.4	-5.0	-1.5	-4.4	-3.1
Loud music exposure frequency	4.2	4.6	8.9	1.3	2.3	2.8	1.8	0.7	1.1	1.9	2.5	2.0	2.9	0.7	0.5	2.0	2.5	2.9	3.0	2.9
Mood swings	4.2	7.6	35.0	-0.4	2.8	-0.6	-3.5	1.9	0.4	-0.6	-2.1	0.1	-0.2	-5.9	-5.2	-2.9	-4.3	-0.2	-3.0	-1.7
Unable to work because of sickness or disability	4.1	5.3	10.8	-2.0	-1.8	-1.6	-1.8	-2.1	-3.3	-2.6	-2.1	-2.6	-2.3	-2.3	-2.9	-2.3	-2.5	-1.9	-2.0	-2.3
Neuroticism (Nagel 2018)	4.0	9.5	37.2	-2.0	1.7	-1.4	-2.9	1.1	0.6	-1.5	-3.7	-0.4	-0.7	-6.1	-5.5	-3.7	-4.9	-1.2	-3.7	-2.5
Hypothyroidism (self reported)	4.0	9.1	26.0	2.2	1.2	3.1	1.8	-0.6	-0.0	2.3	2.8	1.4	2.0	3.9	3.5	4.0	5.1	2.5	4.9	4.0
Forced expiratory volume in 1-second (FEV1)	4.0	13.6	26.4	-1.4	-3.2	-4.7	-3.5	-2.1	-2.8	-3.4	-3.6	-4.3	-5.1	-2.6	-2.0	-3.3	-4.2	-4.9	-4.5	-4.3
Alzheimer’s Disease (including proxy)	3.9	5.7	18.9	-0.4	1.3	-1.1	-4.3	2.0	1.2	-0.2	-1.6	0.3	-1.1	-3.7	-3.5	-2.5	-3.9	-0.5	-3.5	-2.2
Hypertension (Self-reported)	3.9	10.8	50.4	0.1	7.1	4.3	-0.9	1.6	1.8	1.8	1.9	2.3	3.5	-6.7	-3.9	0.0	-0.8	3.1	1.8	3.2
Primary Biliary Cirrhosis	3.8	5.4	11.0	-2.8	-2.1	-2.6	-1.8	-2.5	-3.3	-2.9	-2.4	-2.8	-2.8	-1.1	-1.6	-2.1	-1.7	-2.2	-1.5	-2.0
Age when periods started (menarche)	3.8	9.2	30.0	-0.6	-1.2	-3.3	-3.9	1.9	0.9	-1.0	-3.5	-2.0	-3.1	-2.6	-1.7	-2.7	-4.7	-3.5	-5.5	-4.1
High blood pressure	3.8	10.6	50.1	0.2	7.1	4.4	-0.6	1.6	1.8	1.7	1.8	2.1	3.5	-6.8	-3.8	0.0	-0.8	2.8	1.8	3.2
Falls in the last year	3.8	5.2	14.7	-2.9	-0.3	-1.9	-2.1	-2.1	-2.6	-2.2	-1.5	-2.0	-2.0	-3.8	-3.4	-2.0	-2.7	-1.6	-1.8	-1.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	3.8	4.5	12.7	-1.3	-1.9	-2.1	-2.3	0.9	-0.2	-1.5	-2.7	-1.3	-1.9	-0.8	-1.0	-2.6	-3.0	-2.2	-3.6	-3.2
Frequency of tenseness / restlessness in last 2 weeks	3.7	5.7	15.1	-2.4	-0.0	-2.3	-2.7	-0.1	-0.7	-1.9	-2.8	-1.2	-1.6	-3.9	-3.6	-2.7	-3.5	-1.6	-2.9	-2.3
Peak expiratory flow (PEF)	3.6	8.4	17.4	-0.3	-2.5	-3.1	-2.5	-1.0	-1.8	-2.5	-2.8	-3.4	-4.0	-2.1	-1.5	-2.7	-3.7	-4.2	-4.0	-3.7
Chest pain or discomfort	3.6	5.2	12.2	-2.8	-0.4	-2.6	-3.0	-0.1	-0.6	-1.7	-2.7	-0.5	-1.6	-3.0	-3.5	-2.4	-3.1	-1.1	-2.8	-2.4
Frequency of depressed mood in last 2 weeks	3.5	4.9	14.1	-1.9	0.6	-2.1	-2.0	1.6	0.4	-1.0	-2.6	-0.4	-1.1	-3.8	-3.4	-2.4	-3.5	-1.1	-3.0	-2.1
Frequency of unenthusiasm / disinterest in last 2 weeks	3.5	4.6	10.9	-2.4	-0.8	-2.3	-1.4	-0.3	-1.3	-1.8	-2.2	-1.6	-1.8	-3.3	-3.0	-1.9	-3.0	-2.2	-2.6	-2.2
Mouth/teeth dental problems: Bleeding gums	3.5	4.5	13.2	2.2	3.6	3.0	-1.3	2.8	2.6	1.8	1.3	2.4	3.1	-1.6	-1.4	0.1	-0.2	2.5	0.5	1.3
Hypothyroidism/myxoedema (self-reported)	3.5	6.9	15.6	2.0	2.0	2.9	1.6	0.1	1.0	2.5	2.9	1.9	2.2	2.3	2.4	3.5	3.9	2.6	3.9	3.6
Illnesses of siblings: Diabetes	3.5	4.3	7.9	0.7	1.1	1.8	1.6	1.1	0.9	1.9	2.5	2.2	2.6	2.2	1.4	2.4	2.8	2.7	2.8	2.4
Type 2 Diabetes (T2D) (2018)	3.4	6.4	16.4	1.7	1.2	2.9	2.4	1.7	1.6	2.0	1.8	3.2	4.0	3.2	-0.2	1.9	3.1	4.0	2.9	2.1
Major Depression (MDD)	3.3	4.0	10.6	-2.6	-0.5	-1.6	-2.3	-0.8	-1.1	-2.2	-2.2	-0.8	-0.7	-2.8	-3.2	-2.8	-2.7	-0.8	-1.9	-1.9
Depression (self-reported)	3.3	4.0	8.4	-1.8	-1.8	-2.3	-2.0	-1.6	-2.4	-2.3	-2.3	-1.5	-1.9	-1.3	-2.9	-2.2	-1.9	-1.4	-1.5	-2.1
Whole body water mass	3.3	18.7	42.2	-2.9	-5.6	-3.7	-2.8	-5.5	-6.5	-5.5	-4.2	-5.6	-4.3	-0.6	-4.7	-3.7	-2.6	-4.2	-2.4	-4.5
Smoking Status	3.2	7.6	17.9	-1.5	-1.7	-3.0	-4.2	-0.3	-2.0	-2.2	-3.3	-2.0	-3.1	-2.0	-3.3	-3.1	-3.6	-1.8	-3.5	-3.4
Ever unenthusiastic/disinterested for a whole week	3.2	4.0	8.2	-1.4	-1.9	-1.3	-1.9	-2.1	-2.9	-2.5	-2.4	-2.4	-1.8	-0.8	-2.6	-2.1	-1.5	-1.6	-1.3	-2.1
Glaucoma (self-reported)	3.2	3.7	9.4	-1.1	-2.4	-2.5	-1.0	-0.3	-0.8	-1.7	-2.4	-1.2	-1.6	-0.1	-2.3	-2.1	-2.3	-1.7	-2.8	-3.1
Migraine (self-reported)	3.2	4.0	9.3	-0.4	-1.5	-3.0	-0.5	-0.8	-1.9	-1.9	-2.2	-2.1	-3.0	-1.8	-0.8	-1.7	-2.4	-2.2	-2.7	-2.2
Whole body fat-free mass	3.2	18.0	41.6	-2.7	-5.4	-3.6	-2.8	-5.3	-6.5	-5.4	-4.1	-5.5	-4.3	-0.7	-4.7	-3.7	-2.6	-4.2	-2.4	-4.4
Vascular/heart problems diagnosed by doctor	3.2	8.6	40.1	0.1	-6.3	-4.0	0.2	-1.1	-1.4	-1.3	-1.6	-2.0	-3.4	6.0	3.5	0.1	0.6	-2.6	-1.9	-3.0
Depression (Nagel 2018)	3.1	4.6	10.4	-2.0	-0.6	-2.2	-2.0	1.2	-0.0	-1.3	-2.9	-0.4	-1.4	-2.6	-3.2	-2.5	-3.2	-1.4	-3.1	-2.6
Supplements: Zinc	3.0	3.3	6.6	-2.6	-1.6	-2.3	-1.0	-2.1	-1.6	-2.1	-1.8	-1.9	-2.3	-1.4	-0.1	-1.9	-1.7	-1.8	-1.6	-1.5
Diabetes (father)	3.0	3.8	7.1	1.5	1.2	2.7	1.7	0.5	0.7	2.1	2.2	1.3	2.3	1.8	1.2	2.7	2.6	1.6	2.5	2.3
Blood Eosinophil Count	2.9	22.0	66.9	4.0	8.2	5.0	1.5	5.5	4.4	6.4	5.9	5.9	3.5	-1.7	2.0	3.6	2.0	5.6	2.9	5.3
Nervous feelings	2.9	5.4	19.1	-0.8	1.5	-0.8	-2.7	2.6	1.8	-0.1	-1.7	0.5	0.3	-4.0	-4.4	-2.0	-3.7	-0.5	-3.1	-2.0
Hair/balding pattern: Pattern 2	2.9	3.7	7.6	-1.2	-0.7	-1.9	-2.4	0.0	-1.5	-1.4	-1.7	-1.5	-2.6	-2.1	-1.1	-2.0	-2.8	-2.2	-2.8	-2.2
Illnesses of father: High blood pressure	2.9	3.6	23.5	-0.1	3.3	1.0	-3.0	1.0	0.1	0.5	0.3	0.1	-0.1	-4.8	-2.7	-1.0	-2.3	0.3	-1.1	0.2
Knee pain experienced in last month	2.8	4.4	10.1	-2.1	-1.9	-2.5	-3.2	0.7	-0.6	-1.5	-2.1	-0.6	-1.7	-1.0	-2.8	-2.1	-2.7	-1.2	-3.1	-3.0
Friendships satisfaction	2.8	3.5	5.3	-1.1	-1.2	-2.2	-1.7	-0.9	-1.4	-1.9	-2.3	-1.9	-2.2	-1.8	-1.8	-1.7	-2.3	-1.9	-2.3	-2.1
Ever taken oral contraceptive pill	2.8	3.1	6.4	-0.4	-1.9	-2.1	0.2	-0.7	-1.6	-1.9	-1.8	-2.2	-2.2	-0.9	-0.8	-1.7	-2.0	-2.5	-2.3	-2.3
Triglycerides	2.7	4.4	12.5	1.1	2.3	2.5	1.8	2.1	2.3	2.2	1.3	3.0	3.5	0.7	0.2	1.5	1.7	2.7	2.0	2.1
Arm fat-free mass (right)	2.7	14.0	28.7	-2.8	-4.3	-3.6	-2.7	-4.5	-5.4	-4.7	-3.8	-4.5	-3.8	-1.2	-4.5	-3.5	-2.6	-3.4	-2.3	-3.8
Mean time to correctly identify matches	2.7	5.1	15.6	-1.0	-3.2	-1.7	-3.9	-1.9	-2.7	-2.5	-1.6	-2.8	-2.2	0.4	-0.6	-2.2	-1.6	-2.3	-2.0	-2.6
Illness, injury, bereavement, stress in last 2 years	2.7	3.3	12.6	0.5	-0.8	0.9	2.3	-0.8	0.7	0.9	1.3	0.6	1.1	3.5	3.3	2.1	2.9	0.5	2.1	1.5
Ever depressed for a whole week	2.7	3.3	6.0	-1.8	-1.9	-1.6	-1.5	-1.6	-1.7	-2.1	-1.9	-1.8	-1.4	-1.0	-2.4	-1.9	-1.9	-1.6	-1.8	-2.2
Cholesterol lowering medication	2.7	4.0	11.0	1.6	1.7	2.8	1.5	1.4	1.8	1.7	1.3	2.2	3.3	1.6	-0.4	1.5	2.2	2.6	2.4	2.0
Fasting Glucose	2.6	3.1	14.6	-0.8	-3.2	-1.6	1.0	-1.7	-3.3	-1.7	-0.8	-0.6	-1.0	3.8	0.7	-0.5	1.5	0.6	1.1	-0.6
Reproduciblity of spirometry measurement using ERS/ATS criteria	2.6	3.1	5.8	0.3	2.2	1.7	0.5	1.0	1.8	2.3	1.7	2.0	1.5	0.4	1.1	2.4	1.8	2.2	2.0	2.4
Arm predicted mass (right)	2.6	13.5	29.3	-2.6	-4.4	-3.4	-2.6	-4.5	-5.4	-4.6	-3.7	-4.4	-3.6	-0.8	-4.4	-3.5	-2.4	-3.3	-2.2	-3.8
Supplements: Calcium	2.6	2.9	5.7	-2.3	-2.1	-2.4	0.4	-2.2	-1.3	-2.0	-1.9	-1.9	-1.7	-1.0	-0.4	-1.2	-1.2	-2.2	-1.3	-1.5
Prostate Cancer	2.5	3.5	12.3	-0.3	-0.1	-1.5	-0.9	1.1	1.1	-0.7	-2.0	-1.2	-1.0	-2.7	-1.5	-2.2	-3.3	-2.1	-3.5	-2.4
Hair/balding pattern: Pattern 3	2.5	3.7	9.1	0.7	1.6	2.6	2.1	1.3	1.4	1.6	2.0	2.1	3.0	1.2	0.6	1.3	2.1	2.7	2.4	2.1
High blood pressure (siblings)	2.5	3.5	17.6	0.4	4.2	2.5	-1.6	1.2	1.1	1.7	1.7	1.5	1.3	-3.2	-1.1	0.5	-0.1	2.0	1.1	2.1
Risk taking	2.5	3.7	9.9	-1.4	-1.9	-1.4	-0.8	-2.1	-3.1	-2.3	-1.6	-2.4	-2.3	-1.0	-0.8	-1.9	-1.7	-2.4	-1.7	-1.9
Blood clot in the leg (DVT)	2.4	3.1	11.1	-3.3	-1.4	-2.7	-0.8	-2.2	-1.2	-1.9	-2.5	-0.9	-1.7	-0.5	-1.3	-2.4	-1.1	-0.5	-0.9	-1.4
Family relationship satisfaction	2.4	2.9	5.4	-0.8	-0.9	-1.6	-1.8	-1.4	-1.5	-1.8	-2.3	-1.8	-1.4	-1.8	-2.2	-1.8	-2.1	-1.5	-1.9	-1.8
Arm fat-free mass (left)	2.4	12.0	26.7	-2.3	-4.0	-3.1	-2.7	-4.0	-5.2	-4.3	-3.4	-4.1	-3.4	-0.9	-4.6	-3.2	-2.4	-3.0	-2.1	-3.6
Medication: Omeprazole (e.g. Zanprol)	2.4	2.9	6.4	1.7	1.4	1.7	1.5	2.5	1.6	2.2	1.8	2.3	1.4	1.4	1.3	1.6	1.4	2.0	1.1	1.4
Lupus	2.3	3.4	7.8	-1.6	-2.8	-2.5	-0.0	-2.0	-1.6	-2.3	-2.2	-2.0	-2.3	0.0	-0.3	-1.3	-1.3	-2.3	-1.8	-2.1
Cardiovascular Disease	2.3	7.5	34.3	0.0	5.3	3.8	-0.9	0.2	0.4	0.4	0.6	1.0	3.1	-5.9	-5.4	-1.0	-1.3	1.9	1.1	1.7
Alcohol usually taken with meals	2.3	3.7	8.3	1.7	1.6	1.6	2.8	1.9	2.9	2.6	1.5	2.0	1.8	1.5	1.5	2.1	1.6	1.9	1.2	1.6
Financial difficulties in last 2 years	2.3	3.2	8.2	-1.8	-0.3	-1.7	-2.2	-0.8	-1.1	-1.5	-1.7	-1.7	-1.9	-2.9	-1.7	-1.7	-2.4	-1.8	-1.9	-1.5
Alcohol intake versus 10 years previously	2.3	3.5	9.1	1.6	0.4	2.4	1.8	1.6	1.2	1.6	1.4	1.6	2.4	3.0	1.3	1.5	2.4	2.4	1.9	1.5
Medication: Blood pressure	2.3	4.4	17.5	0.6	4.2	3.2	0.5	1.2	1.7	1.6	1.5	1.7	3.1	-3.1	-1.8	0.4	0.2	2.0	1.5	2.2
Rheumatoid Arthritis	2.2	3.0	8.4	0.2	0.6	1.1	2.9	0.8	1.6	1.3	1.6	2.0	2.1	1.8	2.3	1.6	2.1	1.8	1.9	1.8
Stomach or abdominal pain in last month	2.2	2.8	11.9	-0.7	0.6	-0.9	-2.2	0.8	0.1	-0.4	-1.2	-0.3	-0.9	-2.8	-3.4	-1.9	-2.7	-0.3	-2.1	-1.6
Hair/balding pattern: Pattern 4	2.2	5.4	12.1	1.0	0.9	1.9	3.1	-0.9	1.8	1.6	2.4	1.6	2.4	2.3	2.5	3.0	3.5	1.8	3.4	2.9
Fractured/broken bones in last 5 years	2.2	2.9	5.1	-1.9	-1.0	-2.2	-1.0	-0.7	-1.1	-1.7	-2.0	-1.5	-1.6	-2.2	-0.7	-1.7	-2.2	-2.1	-2.1	-1.7
Arm predicted mass (left)	2.2	11.3	23.8	-2.3	-4.0	-3.0	-2.6	-3.7	-4.9	-4.1	-3.5	-3.8	-3.0	-0.7	-4.8	-3.2	-2.3	-2.8	-2.1	-3.7
Diabetes (self-reported)	2.1	3.2	7.1	1.5	0.3	2.0	2.0	0.7	0.9	1.2	1.8	1.9	2.3	2.7	0.2	1.9	2.4	2.5	2.2	1.5
Health satisfaction	2.1	2.8	12.8	-1.0	0.1	-0.9	-1.0	-1.2	-1.0	-1.5	-1.5	-1.4	-0.5	-3.1	-3.6	-1.6	-2.2	-0.8	-1.5	-1.4
Eye problems/disorders: Cataract	2.1	2.5	7.2	1.1	-0.3	1.4	1.3	-0.7	-0.6	0.5	1.8	0.7	1.0	2.6	1.8	1.7	2.7	1.2	2.6	1.7
Deep venous thrombosis (DVT) (self-reported)	2.1	2.7	10.4	-3.2	-1.2	-2.3	-0.9	-2.4	-1.4	-1.8	-2.3	-1.0	-1.6	-0.4	-1.2	-2.1	-0.9	-0.4	-0.6	-1.1
Mean Putamen Volume	2.0	2.3	4.4	1.1	1.9	2.0	-0.7	1.3	0.7	2.0	2.0	1.6	1.7	0.2	-1.1	1.5	1.2	2.1	1.4	1.5
Medication for pain relief, constipation, heartburn	2.0	3.4	7.3	-1.9	-2.2	-2.4	-2.4	-2.4	-1.7	-1.7	-1.6	-2.7	-2.5	-0.5	-0.2	-0.9	-1.0	-2.2	-1.1	-1.5
Osteoarthritis (self-reported)	2.0	2.6	4.5	-1.1	-1.8	-1.6	0.4	-1.9	-2.0	-2.1	-1.8	-1.9	-1.2	-0.7	-1.9	-1.6	-1.3	-1.8	-1.1	-1.8
Schizophrenia (2014)	1.9	4.3	17.4	-1.4	-0.8	-1.4	-4.2	-0.9	-2.6	-2.1	-1.9	-1.2	-1.6	-1.9	-3.1	-2.5	-2.2	-0.2	-1.8	-1.9
Number of incorrect matches in round	1.9	3.2	10.2	2.7	-0.2	1.3	0.7	1.1	1.3	1.4	1.7	1.4	0.8	3.1	3.2	1.6	2.4	1.0	1.7	1.4
Worrier / anxious feelings	1.9	3.6	10.4	-0.1	0.0	-1.2	-2.3	1.0	0.1	-1.0	-2.1	-0.6	-0.6	-2.8	-3.2	-2.3	-3.1	-1.0	-2.8	-2.3
Medication: Blood pressure	1.9	3.3	25.5	-0.1	3.7	1.6	-1.0	-0.4	-0.2	-0.2	0.7	0.1	0.7	-5.0	-2.8	-0.8	-1.4	0.7	0.6	1.2
Diabetes diagnosed by doctor	1.9	3.1	10.3	1.4	-0.2	1.7	2.1	0.2	0.3	0.9	1.4	1.6	2.2	3.2	0.0	1.7	2.7	2.4	2.3	1.3
Supplements: Fish oil (including cod liver oil)	1.9	2.4	6.7	1.9	0.0	1.2	2.3	-0.5	0.2	1.4	2.3	0.3	0.8	1.6	2.6	2.4	1.8	0.3	1.5	1.5
Medication: Bendroflumethiazide	1.9	2.9	17.7	-0.4	3.6	1.8	-1.0	0.8	1.0	0.7	0.2	0.4	1.2	-4.2	-2.6	-0.5	-1.3	0.8	-0.0	0.9
Ever smoked	1.9	3.2	7.0	-1.1	-0.7	-2.2	-2.5	-0.7	-1.4	-1.6	-2.1	-1.4	-2.6	-2.0	-1.0	-2.0	-2.3	-1.4	-2.2	-1.8
Ulcerative Colitis	1.8	2.6	4.9	0.1	1.2	1.0	0.8	1.0	1.1	2.1	1.8	1.8	1.4	1.4	1.7	2.2	2.2	1.9	1.9	2.1
Systolic blood pressure, automated reading	1.8	5.1	39.1	-2.7	2.8	0.2	-1.6	-2.0	-2.5	-1.3	-0.5	-1.4	-1.0	-6.2	-3.0	-1.1	-1.9	-0.8	0.3	0.9
Pack years adult smoking proportion	1.8	2.8	9.1	-0.5	-0.3	-0.6	-1.6	-0.2	-1.7	-1.8	-2.0	-0.6	-1.2	-1.9	-3.0	-2.7	-2.3	-0.0	-1.8	-1.8
Worry too long after embarrassment	1.8	3.0	5.5	-0.8	-0.7	-1.5	-2.0	-1.3	-1.2	-1.8	-2.0	-2.1	-1.9	-2.4	-1.5	-1.7	-2.2	-1.9	-1.7	-1.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.8	2.3	5.0	-0.4	-1.1	-1.6	-1.4	-0.7	-1.3	-1.3	-1.6	-1.4	-1.5	-1.6	-2.2	-1.5	-2.0	-1.2	-2.0	-1.9
Pack years of smoking	1.8	2.6	8.0	-0.7	-0.6	-0.6	-1.7	-0.3	-2.0	-1.9	-2.0	-0.6	-1.2	-1.4	-2.8	-2.7	-2.0	0.1	-1.6	-1.8
Medication: Ramipril	1.7	2.2	11.7	-0.1	1.7	0.4	-2.3	0.4	-0.4	-0.4	-0.1	0.1	-0.1	-3.4	-3.3	-1.2	-1.9	0.2	-0.9	-0.4
Illnesses of siblings	1.7	2.4	7.9	0.5	-2.8	-1.8	1.2	-0.9	-0.5	-1.4	-1.6	-1.9	-1.7	1.1	0.3	-0.5	-0.8	-2.5	-1.7	-2.1
Father’s age at death	1.7	2.2	5.7	0.5	0.4	0.7	0.4	1.7	2.4	1.8	1.6	1.9	1.3	1.8	2.3	2.0	1.5	0.6	0.9	1.1
Illnesses of mother	1.7	2.1	11.9	0.1	-1.3	-0.3	1.2	-0.6	-0.1	0.8	1.0	0.3	-0.2	3.0	3.5	1.8	2.0	0.1	1.2	0.8
Number of full brothers	1.7	2.1	5.0	-0.1	-0.6	-1.0	-1.6	-1.7	-1.5	-1.8	-0.9	-1.6	-1.8	-2.2	-0.4	-1.5	-1.9	-1.7	-1.6	-1.2
Average weekly champagne plus white wine intake	1.7	2.4	5.6	-0.4	1.0	-0.5	-2.1	2.3	1.2	0.1	-1.3	1.3	0.2	-1.4	-2.4	-2.2	-2.1	0.7	-2.2	-1.5
Medication: Lisinopril	1.7	2.2	9.3	-0.9	3.1	1.1	-0.1	0.4	1.5	1.0	0.9	1.5	1.9	-2.4	-1.3	0.4	0.1	1.8	1.2	1.7
Basal metabolic rate	1.7	9.7	29.9	-2.0	-4.5	-2.0	-1.6	-4.5	-5.5	-4.0	-2.7	-4.0	-2.5	0.6	-3.9	-2.3	-0.9	-2.5	-0.7	-2.9
Bipolar Disorder or Schizophrenia	1.6	3.9	16.0	-1.2	-0.4	-1.2	-4.0	-0.2	-1.8	-1.6	-1.4	-0.8	-1.4	-2.3	-3.6	-2.1	-2.5	-0.3	-2.1	-2.0
Reaction Time	1.6	3.0	10.4	-0.6	-2.6	-1.0	-3.2	-1.8	-2.2	-1.9	-1.1	-2.4	-1.6	0.8	-0.5	-1.5	-0.9	-1.5	-1.2	-1.9
Fed-up feelings	1.6	2.9	18.5	-1.5	2.1	-0.4	-0.4	0.3	0.4	-0.7	-1.6	0.1	0.4	-4.3	-3.5	-1.5	-2.3	-0.1	-1.0	-0.4
Heel bone mineral density (BMD) T-score, automated (right)	1.6	3.7	10.6	2.0	-2.9	-1.1	-2.6	-1.5	-2.8	-1.3	-0.2	-2.3	-3.3	1.8	0.4	-0.8	-0.6	-2.1	-1.4	-2.0
Mouth/teeth dental problems	1.6	2.5	7.0	-0.9	-2.5	-1.7	1.4	-2.6	-2.1	-1.4	-0.1	-2.3	-2.1	0.6	0.9	0.6	0.3	-2.4	0.2	-0.6
Handedness (chirality/laterality): Left-handed	1.6	1.9	4.3	-0.5	-1.1	-1.3	-0.8	-0.2	-0.6	-1.5	-1.9	-0.8	-0.5	-0.9	-1.9	-1.9	-2.0	-1.1	-2.0	-2.1
Alzheimer’s Disease (in mother)	1.5	1.7	5.6	0.7	1.8	1.1	-2.1	2.4	1.6	0.9	-0.2	1.4	0.6	-1.3	-1.6	-0.7	-1.2	1.3	-1.1	-0.3
Waist Hip Ratio (WHR)	1.5	6.6	26.4	-2.5	-5.1	-2.3	-0.5	-2.0	-1.6	-3.0	-4.2	-1.9	-1.1	2.7	-2.0	-2.0	-0.9	-2.0	-2.0	-3.6
Chronotype (morning person)	1.5	3.4	12.2	0.0	1.5	3.5	1.0	-1.4	-1.5	0.3	1.4	0.2	2.8	0.4	-1.4	0.7	2.2	2.0	3.3	2.2
Other serious medical condition/disability diagnosed by doctor	1.5	2.0	6.9	-1.8	-1.6	-0.9	-0.5	-2.6	-2.6	-1.6	-0.5	-2.1	-1.5	-0.3	-1.0	-0.1	-0.1	-1.4	0.2	-0.6
Tense / ‘highly strung’	1.5	2.5	11.0	0.7	2.6	0.6	-2.4	1.6	1.2	0.7	-0.0	0.8	0.5	-3.3	-2.6	-0.8	-1.9	0.4	-1.2	-0.2
Leg pain on walking	1.5	1.9	8.9	-1.9	0.7	-1.2	-1.1	-1.1	-1.0	-1.1	-1.2	-1.3	-0.9	-3.0	-2.0	-1.2	-1.7	-1.0	-0.8	-0.5
Leg fat-free mass (right)	1.5	7.9	30.7	-1.6	-4.4	-0.8	-0.2	-5.1	-5.5	-3.6	-1.6	-4.0	-1.6	1.7	-2.9	-1.2	0.6	-2.0	0.7	-1.8
Mineral and other dietary supplements	1.5	2.1	7.2	-0.9	-0.5	-0.7	-2.7	0.4	-0.6	-1.4	-1.6	-0.4	-0.9	-1.0	-2.7	-2.0	-1.7	-0.2	-1.5	-1.7
Financial situation satisfaction	1.5	1.9	4.0	-0.3	-1.1	-2.0	-1.8	-0.5	-0.7	-1.0	-1.4	-1.1	-1.3	-1.2	-1.6	-1.0	-1.8	-1.4	-1.8	-1.7
Taking other prescription medications	1.4	2.1	7.0	0.0	0.3	1.3	1.0	-0.9	-0.5	0.9	1.4	0.9	1.6	1.5	-0.5	2.0	2.4	1.9	2.6	1.8
Diverticular disease/diverticulitis (self-reported)	1.4	1.6	6.1	0.8	-0.2	1.1	2.0	1.0	1.1	1.4	1.0	1.5	1.2	2.5	0.5	1.4	1.4	1.3	0.8	0.5
Medication: Lansoprazole	1.4	1.6	4.3	0.8	1.1	1.4	0.4	2.1	1.7	1.5	0.9	1.9	1.6	0.6	-0.6	0.7	0.5	1.9	0.4	0.6
Medication: Amlodipine	1.4	2.0	12.7	-0.7	2.2	1.3	-0.9	-0.8	-1.0	-0.6	-0.1	-0.2	1.0	-3.6	-2.6	-1.2	-1.0	0.7	0.5	0.7
Emphysema/chronic bronchitis	1.4	1.6	5.4	-1.8	-1.2	-0.5	-1.1	-1.2	-1.6	-1.5	-1.5	-1.2	-0.3	-0.5	-2.3	-1.1	-1.0	-0.5	-0.7	-1.3
Medication: Gliclazide	1.4	1.6	6.0	0.7	-0.2	1.0	0.7	-0.1	0.1	0.7	1.2	1.2	1.4	2.4	0.7	1.3	2.0	1.6	1.9	1.2
Leg predicted mass (right)	1.4	7.7	30.1	-1.6	-4.4	-0.8	-0.2	-5.0	-5.5	-3.5	-1.6	-3.9	-1.6	1.8	-2.9	-1.2	0.6	-1.9	0.8	-1.8
Schizophrenia (2018)	1.3	2.6	9.7	-1.2	-0.8	-0.2	-3.1	-0.8	-2.2	-1.7	-1.5	-1.2	-0.9	-1.3	-2.8	-1.9	-1.6	-0.2	-1.2	-1.5
Schizophrenia vs Biploar Disorder	1.3	1.7	6.6	-0.1	-0.6	-0.4	-2.6	-1.1	-1.6	-1.3	-1.2	-1.7	-1.3	-1.1	-0.4	-1.5	-1.4	-0.9	-1.3	-1.1
Heel T-Score	1.3	10.6	42.4	5.0	-3.0	-1.5	-6.3	-0.4	-3.6	-0.2	1.4	-2.3	-6.5	3.8	4.1	-0.2	0.1	-2.0	-1.7	-1.7
Medication for hormone replacement therapy	1.3	1.4	5.4	-1.1	-1.4	-1.3	0.5	-1.1	-2.3	-1.4	-0.5	-1.3	-1.9	0.2	1.3	-0.9	-0.3	-1.2	-0.4	-0.6
Leg fat-free mass (left)	1.3	6.9	27.5	-1.5	-4.2	-0.6	-0.2	-4.8	-5.2	-3.3	-1.4	-3.7	-1.3	1.9	-2.7	-1.0	0.7	-1.7	0.9	-1.6
Heel bone mineral density (BMD) T-score, automated (left)	1.3	3.0	9.1	2.1	-2.4	-0.7	-2.5	-1.3	-2.6	-1.0	-0.1	-2.0	-3.0	1.7	0.7	-0.9	-0.5	-1.8	-1.1	-1.7
Serious illness, injury or assault to yourself	1.3	1.6	4.4	1.1	1.7	0.8	0.7	1.0	0.9	1.4	1.7	1.6	1.3	-0.5	-0.4	1.3	0.9	2.1	1.2	1.5
Leg predicted mass (left)	1.3	6.6	26.4	-1.4	-4.2	-0.6	-0.1	-4.7	-5.1	-3.2	-1.3	-3.6	-1.2	2.0	-2.5	-0.9	0.8	-1.7	1.0	-1.5
Exposure to tobacco smoke outside home	1.3	1.7	5.7	0.0	1.8	1.0	0.7	0.9	0.8	0.6	0.7	1.9	2.4	-0.9	-1.8	0.1	0.4	2.3	1.2	1.1
Medication: Seretide 50 evohaler	1.3	1.5	4.2	-1.2	-1.3	-0.9	-1.3	-1.7	-1.9	-1.8	-0.8	-1.3	-0.5	-0.8	-2.1	-0.9	-0.7	-0.6	-0.3	-0.9
Ever had bowel cancer screening	1.3	1.5	5.4	1.1	-0.3	0.9	1.9	1.7	1.4	1.1	0.8	1.4	1.2	2.3	1.3	0.5	0.9	1.2	0.2	0.2
Diastolic blood pressure, automated reading	1.3	3.9	26.8	-0.6	4.3	1.5	-2.2	0.6	0.2	0.9	0.7	0.5	0.3	-5.2	-2.4	0.0	-1.1	1.1	0.7	1.8
Breast Cancer	1.2	2.9	9.4	1.1	3.1	1.6	-1.4	2.6	1.8	1.4	0.0	2.0	1.5	-2.2	-2.3	-0.6	-0.9	1.8	-0.2	0.6
Medication: Co-codamol	1.2	1.4	4.7	-0.4	1.4	1.0	0.4	1.9	0.8	1.5	1.1	2.1	1.1	0.3	-0.5	0.5	0.5	2.2	0.7	0.9
Impedance of leg (right)	1.2	5.8	16.6	-0.9	2.3	-1.9	-3.0	4.1	3.3	1.2	-2.1	1.8	-0.6	-3.3	-1.1	-1.7	-3.5	0.2	-3.7	-1.5
High blood pressure (mother)	1.2	1.7	11.3	0.9	1.2	0.9	-0.1	-0.4	-0.3	-0.8	-0.3	-0.8	0.5	-3.1	-3.4	-1.1	-1.4	-0.4	-0.5	-0.4
Past tobacco smoking	1.2	2.3	4.6	1.3	1.3	1.7	1.7	1.6	1.9	1.7	1.7	1.4	2.1	1.0	0.9	1.6	1.4	1.2	1.3	1.4
Commuting to job workplace: Walk	1.2	1.3	4.4	-1.4	-0.4	-0.4	-0.1	-0.7	-1.1	-1.5	-1.9	-0.6	-0.2	-1.2	-1.8	-2.1	-1.3	-0.2	-0.7	-1.0
Bipolar Disorder (2018)	1.1	1.8	6.3	-0.5	0.3	-1.7	-2.5	0.7	-0.2	-0.4	-0.4	0.2	-1.2	-2.1	-2.3	-1.0	-1.9	-0.1	-1.8	-1.2
Crohns Disease (2012)	1.1	1.8	4.9	0.4	1.0	1.7	0.2	-0.1	-0.8	1.0	2.0	0.7	1.0	0.9	0.9	1.4	2.0	1.6	2.2	2.0
Impedance of leg (left)	1.1	5.3	15.6	-0.9	2.6	-1.6	-2.7	3.9	3.3	1.3	-1.9	2.0	-0.3	-3.2	-1.3	-1.6	-3.2	0.7	-3.2	-1.2
Hayfever/allergic rhinitis (self-reported)	1.1	1.5	3.7	-0.3	1.3	1.2	1.3	1.3	1.5	1.5	0.6	1.7	1.9	0.5	0.1	1.1	1.1	1.2	1.1	1.2
Noisy workplace	1.1	1.3	4.5	-0.9	-0.1	0.2	-1.1	-1.8	-1.7	-1.4	-0.5	-1.4	-0.5	-1.6	-2.1	-1.2	-0.8	-0.6	0.0	-0.4
Eye problems/disorders: None of the above	1.1	1.3	3.5	-0.8	0.4	-1.2	-1.2	0.8	0.7	-0.2	-1.4	-0.3	-1.2	-1.8	-0.4	-1.2	-1.9	-0.9	-1.8	-1.1
Number of self-reported non-cancer illnesses	1.1	1.9	8.8	-2.3	0.5	-0.5	-0.1	-1.2	-1.1	-1.2	-1.3	-0.9	-0.1	-2.9	-3.0	-0.8	-1.3	-0.5	-0.4	-0.4
Commuting to job workplace: Public transport	1.1	1.3	3.4	-0.9	-0.9	-0.7	0.4	-1.8	-1.2	-1.7	-1.3	-1.8	-1.1	-1.0	-0.4	-1.0	-0.7	-1.8	-0.4	-0.7
Basal cell carcinoma (self-reported)	1.1	1.3	3.9	-0.4	1.7	1.6	0.5	-0.3	-0.2	0.9	1.5	0.2	0.9	-0.9	1.1	1.4	1.0	1.0	1.6	2.0
Blood Red Count	1.0	10.1	37.0	2.0	-1.8	1.4	4.2	-1.0	1.0	1.7	1.8	-0.1	1.1	6.1	5.9	4.6	4.9	0.1	3.6	2.5
Weight	1.0	5.0	17.4	0.0	-1.6	2.5	1.9	-1.8	-2.4	0.1	1.3	0.3	2.5	4.2	-1.4	1.6	3.6	2.3	3.7	1.3
Medication: Paracetamol	1.0	1.6	7.6	1.1	0.9	1.7	2.8	0.6	0.1	1.0	1.2	1.2	1.2	1.0	0.3	0.9	1.4	1.5	1.5	1.2
Medication: Omeprazole	1.0	1.3	2.9	1.4	0.6	1.2	1.3	1.7	0.9	1.4	1.1	1.2	0.8	1.3	1.2	1.1	0.9	0.9	0.6	0.8
Commuting to job workplace: Car/motor vehicle	1.0	1.1	3.4	1.5	0.7	0.5	-0.4	1.8	0.6	1.5	1.5	1.5	0.5	1.2	0.5	0.9	0.7	1.4	0.3	0.5
Long-standing illness, disability or infirmity	1.0	1.5	4.9	-2.2	-0.9	-0.9	-1.9	-1.8	-2.1	-1.2	-0.8	-1.0	-0.9	-0.8	-1.9	-0.5	-0.4	-0.2	0.1	-0.5
Irritability	1.0	1.7	10.5	-0.5	0.4	-0.4	-0.9	1.1	0.1	-0.4	-1.3	0.5	0.2	-1.9	-3.2	-1.5	-1.9	0.2	-1.6	-1.3
Tanning	0.9	11.6	29.8	-2.6	0.1	-2.4	-4.6	-0.9	-2.1	-2.5	-3.1	-3.4	-3.1	-5.5	-3.7	-4.0	-5.0	-2.9	-4.2	-3.2
Chronic bronchitis/emphysema (father)	0.9	1.0	3.4	-0.9	-1.3	-0.5	-0.9	-1.1	-1.9	-1.2	-1.2	-1.2	-0.9	0.1	-1.2	-0.9	-0.7	-0.6	-0.7	-1.1
Pain all over the body in last month	0.9	0.9	3.2	-0.6	0.2	1.1	1.1	-0.7	-0.6	0.4	0.9	0.5	0.8	1.1	0.3	0.9	1.6	1.1	1.8	1.2
Exposure to tobacco smoke at home	0.9	1.0	3.0	0.1	1.6	1.7	0.5	0.6	1.1	0.7	0.9	1.1	1.7	-1.0	-0.7	0.1	0.1	1.2	0.8	1.0
Ever highly irritable/argumentative for 2 days	0.9	1.1	5.2	-1.1	-1.1	-1.0	-0.1	-1.6	-2.3	-1.5	-0.9	-1.0	-1.1	-0.3	-1.3	-0.6	-0.2	-0.5	0.1	-0.6
Number of children fathered	0.9	1.1	3.3	1.8	0.6	1.5	0.7	0.8	0.4	1.2	1.5	1.1	0.9	1.2	0.4	0.7	1.0	1.1	0.8	0.7
Age at first live birth	0.9	1.7	6.9	0.5	-0.7	0.1	2.5	-0.6	0.4	0.3	0.9	0.1	0.1	1.7	2.6	1.9	1.7	-0.1	1.4	1.2
Pulse wave peak to peak time	0.9	1.1	3.3	0.4	0.2	-0.9	-1.4	1.5	0.4	0.1	-0.6	0.3	-0.7	-0.7	-1.2	-1.4	-1.7	-0.1	-1.8	-1.3
Illnesses of father: Heart disease	0.9	1.3	3.9	-2.0	-1.2	-0.7	-0.3	-1.5	-1.2	-1.3	-1.1	-1.2	-0.2	-0.6	-1.3	-1.0	-0.9	-1.5	-0.7	-1.2
Medication: Paracetamol	0.9	1.4	10.3	0.9	0.3	1.2	3.2	-0.1	-0.4	0.5	0.9	0.7	0.8	1.3	0.7	0.6	1.4	1.0	1.4	1.0
Heart attack/myocardial infarction (self-reported)	0.9	1.1	4.4	-1.8	-0.9	-0.6	0.2	-1.4	-1.4	-1.2	-1.4	-0.9	-0.1	-0.1	-2.1	-0.8	-0.3	-0.5	-0.1	-0.8
Bipolar Disorder (2011)	0.8	0.8	5.2	0.0	-0.2	-0.8	-2.3	0.7	-0.1	-0.3	-0.2	0.8	-0.6	-0.5	-1.8	-0.4	-0.9	0.4	-1.0	-0.9
Respiratory disease	0.8	1.7	6.9	-2.6	-0.4	-1.0	-0.5	-1.8	-1.2	-1.6	-1.5	-1.2	-0.2	-1.7	-2.5	-0.8	-0.7	-0.4	0.0	-0.4
Lung FVC	0.8	4.0	14.2	-0.7	-0.5	-2.6	-3.2	-0.5	-1.4	-0.7	-0.7	-2.1	-3.8	-2.4	0.5	-1.2	-2.4	-2.5	-2.5	-1.5
Number of treatments/medications taken	0.8	1.4	6.0	0.7	1.0	1.6	1.8	-0.0	0.0	0.1	1.0	0.9	2.1	-1.0	-2.4	0.7	0.4	1.1	1.1	0.8
Relative age of first facial hair	0.8	1.6	3.9	-0.7	-0.7	-1.1	-1.9	0.7	-1.0	-0.4	-1.2	-0.7	-1.5	-0.9	-1.5	-1.3	-1.8	-0.6	-2.0	-1.7
Multivitamins +/- minerals	0.8	1.0	3.2	-0.2	-1.0	-0.9	1.2	-1.8	-1.2	-1.1	-0.9	-1.8	-1.0	-0.4	0.5	-0.2	-0.3	-1.6	-0.2	-0.4
Supplements: Glucosamine	0.8	1.0	5.7	0.5	-0.9	-0.3	1.0	-1.0	-1.2	-0.3	0.9	-0.6	-1.2	0.9	2.4	0.7	0.8	-1.0	0.6	0.4
Medication: Simvastatin	0.8	1.1	2.7	1.4	0.6	1.6	1.0	0.0	0.8	0.3	0.8	0.6	1.4	1.0	0.6	1.2	1.5	0.8	1.6	1.3
Shortness of breath walking on level ground	0.8	1.0	4.4	-1.7	1.0	0.3	1.0	-0.2	0.0	-0.1	-0.3	0.9	1.3	-1.3	-2.1	-0.6	-0.2	1.3	0.6	0.4
Mouth/teeth dental problems: Loose teeth	0.8	0.9	3.3	-0.6	1.8	0.2	-1.1	0.9	0.2	0.2	-0.0	1.3	0.7	-1.6	-1.4	-0.5	-0.5	1.5	0.2	0.6
Medication: Ibuprofen	0.8	1.0	7.7	1.4	0.3	0.4	2.8	1.3	0.8	0.7	0.5	1.1	0.8	0.7	1.0	0.3	0.2	0.2	-0.1	0.2
Medication: Allopurinol	0.8	1.1	6.3	-1.8	0.2	-0.7	-0.3	-1.4	-0.7	-1.1	-0.6	-1.1	-1.0	-2.5	-0.4	-0.5	-1.1	-1.1	-0.3	-0.1
Overall health rating	0.8	1.8	7.5	-2.5	0.1	-0.8	-0.7	-1.5	-1.6	-1.1	-1.2	-1.0	-0.5	-2.3	-2.7	-0.7	-1.1	-0.2	-0.2	-0.5
Qualifications: NVQ or HND or HNC or equivalent	0.8	0.9	5.2	2.1	0.2	0.8	-0.2	2.3	0.9	0.9	0.7	1.1	0.3	1.0	-0.3	-0.1	-0.2	0.9	-0.6	-0.4
Supplements: Vitamin C	0.8	1.0	3.0	0.6	0.6	0.3	-0.3	1.1	1.2	1.7	1.0	1.3	0.4	0.8	1.3	1.6	0.7	0.9	0.2	0.8
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	1.0	2.8	1.1	1.1	1.7	0.2	0.8	0.3	0.9	1.4	1.1	1.5	0.4	-0.4	0.1	0.6	1.4	0.9	0.8
Number of operations (self-reported)	0.8	1.3	4.2	0.2	-0.2	0.2	1.1	0.9	0.6	1.1	0.9	1.5	1.2	2.1	1.5	1.1	1.5	1.3	1.0	0.9
HbA1C	0.7	0.7	3.5	-0.6	-0.6	-1.9	-0.3	-1.4	-0.7	-0.9	-0.4	-0.8	-1.3	-0.9	0.1	-0.1	-0.3	-1.1	-0.4	-0.2
Type 2 Diabetes (T2D) (2012)	0.7	0.8	4.4	0.3	1.3	0.9	-0.5	0.2	0.6	0.5	0.4	0.8	1.4	-0.5	-2.1	-0.1	0.2	1.7	0.6	0.5
Average weekly fortified wine intake	0.7	0.8	6.6	-0.6	-0.9	-0.9	0.0	-0.3	0.6	0.2	-0.1	-0.2	-0.9	1.2	2.6	0.9	0.7	-0.5	0.2	0.3
Hayfever, allergic rhinitis or eczema	0.7	1.4	5.9	-0.1	1.2	0.2	-1.6	1.2	1.1	0.2	-0.7	0.3	0.4	-2.1	-2.4	-1.1	-1.7	-0.0	-1.3	-0.7
Hearing difficulty/problems with background noise	0.7	1.0	8.5	-1.4	1.1	-0.8	0.6	0.1	1.0	-0.1	-0.8	0.1	-0.3	-2.9	0.2	-0.4	-1.3	-0.6	-0.9	0.2
Happiness	0.7	0.8	1.8	-0.5	-1.2	-0.8	-0.1	-0.9	-0.5	-1.2	-1.1	-1.1	-0.6	-0.6	-0.5	-0.4	-0.9	-1.4	-1.0	-1.1
Medication: Ibuprofen (e.g. Nurofen)	0.7	0.9	6.0	0.8	0.4	0.1	2.5	1.4	1.1	0.8	0.3	1.3	0.6	0.7	1.3	0.5	0.2	0.4	-0.1	0.3
Prospective memory result	0.7	0.9	4.1	-0.6	0.6	1.6	-0.4	-2.0	-1.6	-0.7	0.6	-0.9	0.3	-1.0	-0.4	-0.2	0.4	0.1	1.2	0.8
Pulse wave reflection index	0.7	0.9	2.7	0.5	1.0	1.6	0.9	0.0	0.5	0.6	0.9	0.3	0.8	0.3	1.6	0.9	1.2	0.3	1.2	1.4
Average weekly red wine intake	0.7	1.0	4.1	0.1	-0.8	-1.1	1.0	-1.0	-0.1	-0.4	-0.1	-1.5	-1.4	-0.8	1.1	-0.0	-1.0	-2.0	-1.2	-0.8
Medication for cholesterol	0.7	1.0	4.0	-0.2	-1.8	-2.0	-1.1	-0.0	0.1	-0.2	-0.8	-0.6	-1.5	1.4	0.8	0.2	-0.3	-0.9	-1.1	-1.2
Commuting to job workplace: Cycle	0.7	0.8	3.8	1.4	-0.0	0.6	0.6	-0.4	0.8	0.5	1.2	-0.3	-0.3	0.6	2.0	1.3	0.9	-0.7	0.6	0.8
Ovarian Cancer	0.6	0.8	4.1	-0.1	-1.1	-0.8	1.5	-0.3	-0.1	0.3	0.4	-0.1	-0.5	1.6	2.0	0.9	0.8	-0.7	0.2	0.1
Average weekly spirits intake	0.6	0.7	1.5	1.2	-0.3	0.6	0.2	-1.2	-0.9	-0.3	0.5	-0.5	-0.6	1.0	0.9	1.1	1.2	-0.3	1.2	0.8
Vitamin and mineral supplements	0.6	0.7	3.1	-0.8	1.0	0.2	-1.8	1.3	0.9	0.1	-0.2	1.0	0.3	-0.9	-1.3	-0.7	-0.7	0.8	-0.5	-0.2
Medication: Atenolol	0.6	0.8	3.4	0.5	1.7	0.9	-1.6	1.0	-0.1	0.2	0.4	0.2	-0.1	-1.8	-0.8	-0.7	-0.9	0.1	-0.4	0.1
Allergy	0.6	1.5	9.1	1.4	-0.6	0.4	1.4	0.0	-0.8	0.2	1.1	0.0	-0.5	2.0	3.0	1.0	1.5	-0.1	1.0	0.7
Pulse rate	0.6	1.1	4.0	-1.0	-2.0	-1.4	1.0	-1.8	-1.1	-0.8	0.2	-0.8	-0.6	1.2	-0.5	0.9	0.8	-0.3	0.8	-0.2
Serious illness, injury or assault of a close relative in last 2 years	0.6	0.7	3.3	0.3	0.8	0.3	-0.8	1.0	0.7	0.1	-0.0	0.1	0.3	-1.7	-1.8	-0.6	-1.2	0.0	-0.8	-0.4
Pulse wave Arterial Stiffness index	0.6	0.7	3.4	-1.0	-0.7	0.2	0.7	-1.9	-0.9	-0.7	-0.2	-0.9	0.1	0.2	0.3	0.8	1.0	-0.5	1.1	0.6
Length of working week for main job	0.6	0.6	2.7	-0.6	-0.2	-1.4	-0.2	-0.6	-1.7	-0.8	-0.0	-0.5	-1.4	-0.7	0.5	-0.9	-0.6	-0.5	-0.4	-0.3
Headache pain in last month	0.6	1.1	5.5	0.6	0.7	0.6	0.3	2.4	2.1	1.1	-0.4	1.3	0.7	-0.4	-0.7	0.0	-0.9	0.7	-1.3	-0.5
Medication for cholesterol, blood pressure or diabetes	0.6	1.0	6.4	-0.2	-1.5	-0.8	0.5	0.7	0.5	0.8	-0.0	0.1	-0.7	2.5	2.0	0.8	0.7	-0.3	-0.4	-0.4
Gout (self-reported)	0.6	0.8	2.1	-1.1	-0.0	-0.6	-1.1	-0.9	-0.5	-1.0	-1.1	-0.8	-0.5	-1.4	-1.1	-0.9	-1.0	-0.7	-0.6	-0.6
Pulse rate, automated reading	0.6	1.9	12.0	0.1	-3.5	-1.3	0.9	-0.9	-0.8	-0.9	0.1	-0.3	-0.7	3.4	-0.3	0.6	1.1	-0.2	0.2	-1.1
Ever had stillbirth, spontaneous miscarriage or termination	0.6	0.7	2.6	0.8	-0.0	-0.2	-0.3	1.0	0.9	-0.0	-1.1	-0.3	-0.2	-0.3	-0.6	-1.0	-1.2	-0.7	-1.6	-1.2
Qualifications: nursing, teaching	0.6	0.9	2.6	0.5	-0.7	0.9	1.5	-1.3	-0.8	-0.1	0.6	-0.7	0.1	1.0	1.6	0.9	1.2	-0.8	1.0	0.7
Pain type(s) experienced in last month: Hip pain	0.6	0.7	2.8	-0.6	-0.7	-0.7	0.0	-1.3	-0.5	-0.7	-0.6	-1.5	-0.9	-1.0	-0.5	0.1	-0.7	-1.7	-0.6	-0.6
Pain experienced in last month	0.6	1.0	4.3	-0.5	-1.0	-0.4	-0.3	-2.1	-1.9	-1.0	0.3	-1.5	-1.1	0.4	1.0	-0.1	0.5	-1.1	0.6	0.1
Alcohol drinker status: Previous	0.6	0.6	4.5	-1.3	-0.2	0.4	0.8	-0.3	-0.1	-0.3	-0.7	0.2	1.1	0.0	-2.1	-0.7	-0.3	1.0	0.0	-0.5
Coronary Artery Disease (CAD)	0.5	0.6	2.0	0.2	0.7	0.9	0.3	-0.2	0.5	0.7	1.4	1.0	0.9	-0.3	-0.9	0.8	0.6	1.1	1.0	0.9
Heart attack	0.5	0.6	3.8	-1.3	-0.6	-0.2	0.5	-1.0	-0.8	-0.8	-1.0	-0.5	0.3	-0.0	-2.0	-0.5	-0.1	-0.2	0.1	-0.5
Wheeze or whistling in the chest in last year	0.5	0.8	4.6	-1.6	1.1	0.1	-0.5	-0.6	-0.2	0.1	-0.6	0.1	0.6	-1.2	-2.1	-0.1	0.0	1.6	0.6	0.6
Neck or shoulder pain in last month	0.5	0.6	2.3	-1.5	-0.1	-1.3	0.7	-0.8	-0.4	-0.5	-0.8	-0.6	-0.7	-1.4	-0.8	-0.2	-0.8	-0.5	-0.5	-0.3
Heart disease (mother)	0.5	0.6	2.9	-0.3	0.9	0.6	-1.4	-0.5	0.1	-0.2	-0.1	-0.8	0.3	-1.7	-1.3	-0.6	-0.8	-0.6	-0.3	-0.1
Number of full sisters	0.5	0.6	4.0	-0.6	0.6	-0.0	-0.2	-0.8	-0.3	-0.8	-0.0	-0.9	-0.7	-2.0	-1.0	-0.5	-1.1	-0.6	-0.5	-0.2
Age at last live birth	0.5	0.7	3.4	0.3	-0.5	-1.2	-0.4	0.2	0.2	-0.2	-0.6	-0.8	-1.9	-0.5	1.0	0.1	-0.9	-1.3	-1.2	-0.7
Tinnitus: Yes, now most or all of the time	0.5	0.6	2.9	0.8	0.8	0.6	-1.3	1.7	0.8	0.4	-0.6	0.5	0.1	-0.3	-0.0	-0.9	-0.8	0.2	-0.9	-0.4
Medication: Atorvastatin	0.5	0.6	4.5	1.3	-0.8	0.5	-0.4	-0.2	-0.4	-0.5	-0.1	0.1	0.6	0.6	-2.1	-0.5	-0.1	0.2	-0.2	-0.8
LDL Cholesterol	0.4	0.7	4.3	1.2	0.4	0.1	0.8	1.6	2.1	0.3	-0.3	0.9	0.7	0.0	-0.7	0.1	-0.4	-0.0	-0.6	-0.4
Allergy or Eczema	0.4	1.1	6.9	-0.3	1.0	0.4	-1.1	0.7	0.9	0.1	-0.6	0.3	0.9	-1.8	-2.6	-0.8	-1.3	0.3	-0.8	-0.5
Diabetes (mother)	0.4	0.5	1.8	-0.1	-0.2	-0.2	1.4	0.8	0.6	0.1	-0.7	0.9	1.1	1.1	-1.1	-0.2	0.3	1.1	0.1	-0.2
Maternal smoking around birth	0.4	0.6	1.9	-0.9	0.7	1.1	-0.9	-0.9	-1.3	-0.4	-0.1	-0.5	0.4	-1.2	-1.4	-0.2	-0.2	0.4	0.4	0.3
Tinnitus: Yes, but not now, but have in the past	0.4	0.4	3.9	0.1	1.2	0.2	0.3	-0.3	0.3	0.2	0.1	-0.5	-0.1	-2.0	-0.7	-0.1	-0.9	-0.1	-0.5	0.2
Had menopause	0.4	0.5	1.6	-0.9	-1.3	-1.1	-0.1	-1.0	-0.6	-0.6	-0.4	-0.7	-0.8	0.4	0.1	-0.1	-0.1	-0.8	-0.3	-0.6
Time employed in main current job	0.4	0.4	3.8	0.3	0.1	-0.0	-2.0	1.1	-0.2	0.1	-0.2	0.4	-0.3	0.1	-0.6	-0.6	-0.5	0.3	-0.7	-0.6
Qualifications: A levels/AS levels or equivalent	0.4	0.8	2.2	0.4	-1.4	-0.8	1.2	0.2	1.0	-0.6	-0.8	-0.1	-0.4	1.3	1.5	-0.4	-0.1	-1.1	-0.7	-0.8
Birth weight of first child	0.4	0.6	2.0	0.7	-1.4	-1.2	0.9	0.0	-0.5	-0.6	-0.8	-0.8	-0.7	1.4	0.4	-0.3	0.0	-0.9	-0.5	-0.9
Qualifications: O levels/GCSEs or equivalent	0.4	0.6	4.4	0.6	-0.8	0.3	1.1	0.3	0.7	0.1	-0.5	0.5	0.9	2.1	0.1	0.4	0.9	0.5	0.3	-0.2
Chronic bronchitis/emphysema (mother)	0.4	0.4	1.1	-0.9	-0.3	-0.6	-1.0	-0.8	-1.1	-0.7	-0.6	-0.7	-0.6	-0.5	-0.8	-0.2	-0.2	-0.2	-0.1	-0.2
Qualifications: College or University degree	0.4	1.2	6.9	0.5	-0.5	-0.2	1.9	-0.8	-0.1	0.5	1.3	0.0	-0.7	0.6	2.6	1.7	1.1	-0.8	0.8	1.0
Back pain experienced in last month	0.4	0.6	4.4	-0.0	1.2	-0.3	1.3	0.0	0.5	-0.2	-0.5	-0.1	-0.1	-2.1	-0.7	-0.3	-1.0	-0.1	-0.4	0.1
Asthma (self-reported)	0.4	0.7	3.6	-1.8	0.7	-0.4	-0.5	-0.8	0.1	-0.1	-0.3	-0.1	0.3	-1.9	-1.8	0.3	-0.3	0.3	0.3	0.4
Osteoporosis (self-reported)	0.4	0.5	3.0	-1.7	-0.4	-0.6	1.6	-0.9	0.1	-0.2	-0.7	-0.5	-0.0	-0.1	0.9	-0.1	0.2	-0.6	0.1	0.1
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.4	0.9	9.3	1.1	0.4	-0.2	-0.3	0.5	0.8	0.8	1.1	0.2	-0.6	0.4	3.0	0.8	0.4	-0.5	0.1	0.7
Wears glasses or contact lenses	0.4	0.4	1.1	1.1	-0.9	-0.3	-1.0	-0.5	-0.5	-0.7	-0.1	-0.8	-0.6	0.3	-0.3	-0.2	-0.3	-1.0	-0.5	-0.7
Impedance of whole body	0.4	2.0	9.4	-0.5	1.6	0.1	-0.6	3.0	3.1	1.6	-0.9	1.8	1.3	-0.4	-0.2	-0.1	-0.8	1.3	-1.1	-0.1
Crohns Disease (2017)	0.3	0.7	2.0	1.0	0.9	1.2	0.1	-0.2	-0.8	0.0	1.4	0.1	0.5	-0.7	-0.3	0.6	0.8	0.9	1.4	1.2
Irritable Bowel Disease (IBD)	0.3	0.7	2.2	0.3	1.0	0.7	0.3	-0.1	-0.6	0.4	1.3	0.2	0.4	-0.4	-0.1	0.9	1.1	1.2	1.5	1.4
Sensitivity / hurt feelings	0.3	0.6	2.1	0.2	0.3	0.3	0.9	0.3	0.3	-0.8	-0.6	-0.3	0.9	-1.4	-1.4	-1.1	-1.0	-0.1	-0.4	-0.5
Relative age voice broke	0.3	0.5	1.7	0.4	0.1	-0.8	-1.2	0.9	0.0	0.6	0.2	-0.3	-1.3	-0.6	0.1	0.1	-0.9	-0.5	-1.2	-0.6
Bilateral oophorectomy (both ovaries removed)	0.3	0.3	1.0	-0.1	0.8	0.6	0.8	0.6	0.3	0.5	0.5	1.0	0.6	-0.3	-0.0	0.2	0.2	0.9	0.4	0.6
Qualifications: CSEs or equivalent	0.3	0.4	1.7	-0.0	0.8	-0.1	-0.2	0.7	0.3	0.3	-0.2	1.1	0.6	-0.6	-1.3	-0.6	-0.5	1.0	-0.2	-0.0
Had other major operations	0.3	0.4	1.7	0.2	-0.0	0.0	0.7	0.8	-0.3	0.6	-0.2	0.6	0.8	1.3	0.6	0.2	0.8	0.9	0.6	0.4
Qualifications: None of the above	0.3	0.7	2.3	-1.3	1.1	0.4	-1.3	-0.2	-0.2	-0.4	-0.8	0.0	0.6	-1.5	-1.4	-0.8	-0.5	0.6	0.2	0.2
Number of live births	0.3	0.5	2.1	-0.9	1.0	-0.1	-1.4	-0.7	-0.5	0.2	0.5	-0.3	-0.7	-0.8	0.9	0.2	0.2	-0.1	0.6	0.8
Mouth/teeth dental problems: Dentures	0.3	0.5	1.3	-0.5	-0.5	-0.6	-1.0	1.0	0.5	-0.1	-1.1	0.4	-0.4	0.7	-0.2	-1.1	-0.6	0.3	-1.1	-1.0
Asthma	0.3	0.7	3.8	-1.5	0.9	-0.4	-0.3	-0.7	0.4	0.0	-0.1	0.1	0.5	-2.0	-1.7	0.4	-0.3	0.4	0.3	0.5
Impedance of arm (left)	0.3	1.5	4.9	-0.6	-0.2	1.2	1.4	0.8	1.5	1.1	-0.1	0.9	2.0	2.2	1.1	1.0	1.5	1.2	1.0	0.7
Medication: Ventolin 100micrograms inhaler	0.3	0.4	1.8	-1.4	0.0	-0.7	0.4	-0.5	-0.8	-0.4	-0.8	-0.1	0.2	-0.4	-1.0	-0.6	-0.1	0.6	0.2	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.3	0.4	1.4	0.8	-0.5	0.0	-1.2	-0.3	-1.1	-0.4	-0.3	-0.5	-0.6	-0.1	-0.5	-0.6	-0.4	-0.5	-0.4	-0.6
Had major operations	0.3	0.3	1.1	-0.4	-0.3	-1.1	0.5	-0.3	0.0	-0.6	-0.7	0.0	-0.2	-0.9	-0.8	-0.4	-0.8	-0.3	-0.7	-0.5
Medication: Aspirin	0.3	0.4	1.4	0.3	1.2	0.9	-0.7	0.2	0.3	0.0	0.5	0.7	0.7	-1.0	-0.8	0.4	0.0	0.6	0.6	0.7
Mouth/teeth dental problems: Mouth ulcers	0.3	0.5	3.4	0.0	1.0	0.3	-0.2	-0.9	-0.8	-0.6	-0.1	-0.4	-0.3	-1.8	0.1	-1.1	-0.7	-0.3	-0.0	0.3
Breast cancer (self-reported)	0.3	0.4	1.3	-0.2	0.2	0.3	-0.4	-0.1	0.1	0.8	0.7	-0.1	0.4	0.7	0.7	1.1	1.1	0.2	1.0	0.8
Illnesses of father: None of the above (group 1)	0.3	0.3	1.1	0.6	-0.0	-0.6	-0.4	1.0	0.9	0.2	-0.2	0.8	-0.0	0.7	-0.3	-0.5	-0.2	1.0	-0.5	-0.4
Ever had prostate specific antigen (PSA) test	0.3	0.3	1.4	-0.8	-0.8	-0.6	0.7	-0.6	-0.1	-0.5	-0.3	-0.4	-0.4	0.4	1.2	0.2	0.2	-0.9	0.0	-0.1
Age started oral contraceptive pill	0.3	0.3	1.4	-0.2	-0.7	0.1	0.7	0.1	0.6	0.1	-0.3	-0.1	0.9	1.2	1.2	0.2	0.6	-0.3	0.2	0.0
Heart disease (siblings)	0.3	0.4	2.7	0.1	-0.7	-0.3	-1.6	0.4	-0.3	-0.4	-0.4	0.0	-0.2	0.4	-0.6	-0.7	-0.5	0.2	-0.6	-0.7
Alzheimer’s Disease (in father)	0.2	0.2	0.5	-0.4	0.0	-0.6	-0.4	0.2	0.4	0.0	-0.5	0.4	-0.5	-0.3	-0.6	-0.4	-0.6	0.1	-0.7	-0.5
Ulcerative Colitis (UC)	0.2	0.3	1.1	-0.5	0.6	0.4	0.5	-0.1	-0.3	0.3	0.6	0.1	0.3	-0.1	0.2	0.5	0.8	1.0	1.0	1.0
Age at First Birth	0.2	0.2	0.9	0.1	0.1	0.4	0.5	-0.0	0.4	0.1	0.5	0.3	0.4	0.3	0.9	0.6	0.6	0.2	0.8	0.7
Lung FEV1/FVC ratio	0.2	0.9	4.3	1.8	0.1	0.2	0.6	1.2	2.1	1.0	1.0	0.8	0.5	0.7	1.2	1.1	0.2	-0.1	-0.3	0.2
Hair Pigment	0.2	5.1	15.3	0.4	-2.6	-3.9	-3.5	0.9	-0.4	-0.5	-1.4	-1.0	-3.9	0.4	-0.1	-0.8	-2.3	-1.8	-3.8	-3.1
Hearing difficulty/problems: Yes	0.2	0.3	2.2	-1.5	0.2	-0.5	0.8	0.4	0.1	-0.0	-0.3	0.7	-0.2	-0.7	0.6	-0.5	-0.4	0.7	-0.3	0.2
Impedance of arm (right)	0.2	1.0	3.0	-0.4	0.0	1.0	0.7	1.4	1.4	1.1	-0.1	1.0	1.7	1.6	0.8	0.7	0.8	1.2	0.4	0.3
Medication: Cholesterol lowering	0.2	0.3	1.6	0.4	-0.5	0.5	-0.1	-1.1	-0.4	-0.9	-0.2	-0.2	0.7	0.2	-1.3	-0.1	0.2	0.2	0.5	-0.2
Smoking status: Previous	0.2	0.3	1.4	-0.1	-0.9	-0.3	-0.4	-1.2	-0.9	-0.7	-0.3	-0.4	-0.6	0.3	-0.3	-0.5	0.1	-0.2	-0.0	-0.4
Medication: Aspirin	0.2	0.2	1.3	0.5	0.5	0.9	-0.6	-0.3	-0.1	-0.4	0.2	0.0	0.6	-0.6	-1.2	0.1	-0.1	0.1	0.4	0.2
Mother’s age at death	0.2	0.3	1.7	0.2	0.5	0.1	0.1	1.3	1.0	0.4	0.0	0.9	0.5	-0.1	0.5	-0.2	-0.1	0.2	-0.3	0.1
High cholesterol (Self-reported)	0.2	0.4	2.6	0.4	0.5	0.8	-0.4	-0.6	0.4	-0.5	-0.3	0.2	1.3	-0.5	-1.6	-0.1	0.1	0.7	0.6	0.3

Hub : Genes

PSMC3

Models

Trait associations