Best TWAS P=1.22e-07 · Best GWAS P=3.02e-10 conditioned to 0.000636
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | CommonMind | Brain Pre-frontal Cortex | PDZRN4 | 0.33 | 0.32 | enet | 23 | 0.35 | 8.5e-44 | 4.3 | 5.3 | 1.2e-07 | 0.78 | 0.99 | 0.01 | TRUE |
2 | GTEx | Skin Sun Exposed Lower leg | PRICKLE1 | 0.13 | 0.01 | lasso | 7 | 0.00 | 1.7e-01 | -5.2 | -5.3 | 1.3e-07 | -0.01 | 0.05 | 0.64 | TRUE |