Best TWAS P=9.16e-18 · Best GWAS P=7.38e-20 conditioned to 0.00935
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | SLC38A2 | 0.02 | 0.02 | blup | 341 | 0.01 | 5.8e-03 | -8.5 | 7.6 | 2.5e-14 | -0.90 | 0.06 | 0.90 | FALSE |
| 2 | NTR | Blood | SLC38A1 | 0.12 | 0.07 | lasso | 6 | 0.08 | 8.4e-24 | 5.2 | -5.2 | 2.4e-07 | 0.08 | 1.00 | 0.00 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | SLC38A2 | 0.10 | 0.06 | blup | 30 | 0.05 | 8.3e-04 | -9.0 | 8.6 | 9.2e-18 | -0.86 | 0.01 | 0.91 | TRUE |
| 4 | The Cancer Genome Atlas | Soft Tissue Sarcoma | SLC38A2 | 0.06 | 0.01 | blup | 30 | 0.03 | 5.1e-03 | -9.0 | 7.7 | 2.0e-14 | -0.92 | 0.02 | 0.74 | FALSE |