[Hub]/) : Traits : Arm fat-free mass (left) :

chr14:72,695,406-74,627,634

Best TWAS P=2.15e-10 · Best GWAS P=2.16e-09 conditioned to 0.00195

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum DCAF4 0.23 0.07 enet 30 0.13 4.3e-07 4.4 5.7 9.6e-09 0.48 0.22 0.74 FALSE
2 GTEx Colon Sigmoid DCAF4 0.30 0.10 lasso 9 0.11 1.3e-04 5.2 6.3 2.6e-10 0.74 0.01 0.93 FALSE
3 GTEx Esophagus Gastroesophageal Junction DCAF4 0.18 0.01 enet 10 0.06 3.0e-03 5.2 6.4 2.2e-10 0.53 0.08 0.43 TRUE
4 GTEx Esophagus Mucosa ZFYVE1 0.10 0.00 lasso 7 0.00 2.0e-01 5.2 5.9 2.7e-09 0.61 0.10 0.65 FALSE
5 GTEx Pancreas DCAF4 0.20 0.15 lasso 4 0.14 2.4e-06 5.2 5.2 1.8e-07 0.60 0.08 0.84 FALSE
6 GTEx Spleen DCAF4 0.47 0.12 enet 10 0.19 1.5e-05 4.4 6.0 1.6e-09 0.63 0.11 0.84 FALSE
7 GTEx Spleen NUMB 0.46 -0.01 enet 28 0.09 3.2e-03 1.2 5.2 1.9e-07 0.48 0.08 0.26 FALSE
8 NTR Blood DCAF4 0.04 0.03 lasso 6 0.03 6.5e-09 5.2 5.4 6.9e-08 0.60 0.09 0.91 FALSE
9 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma DCAF4 0.04 0.02 blup 83 0.03 1.2e-04 4.2 5.1 3.0e-07 0.55 0.02 0.95 FALSE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma DPF3 0.18 0.18 lasso 7 0.22 1.6e-24 4.9 5.7 1.4e-08 0.91 0.00 1.00 FALSE
11 The Cancer Genome Atlas Thyroid Carcinoma DPF3 0.10 0.02 blup 210 0.07 1.9e-07 -2.9 -5.6 2.4e-08 -0.53 0.77 0.16 FALSE