Best TWAS P=5.91e-11 · Best GWAS P=1.72e-15 conditioned to 9.44e-08
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PIGC | 0.11 | 0.00 | enet | 21 | 0.01 | 8.4e-02 | -0.19 | 6.5 | 5.9e-11 | 0.52 | 0.04 | 0.48 | TRUE |
| 2 | GTEx | Skin Sun Exposed Lower leg | PIGC | 0.08 | 0.02 | lasso | 5 | 0.02 | 8.8e-03 | 5.01 | 5.2 | 2.0e-07 | -0.04 | 0.52 | 0.02 | FALSE |
| 3 | GTEx | Testis | METTL13 | 0.29 | 0.05 | lasso | 10 | 0.09 | 9.9e-05 | -3.29 | 5.7 | 1.0e-08 | 0.53 | 0.16 | 0.43 | FALSE |