[Hub]/) : Traits : Arm fat-free mass (left) : ← →

chr1:154,282,146-155,910,830

Best TWAS P=2.55e-33 · Best GWAS P=1.82e-30 conditioned to 1

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
8	GTEx	Skin Sun Exposed Lower leg	ADAM15	0.14	0.09	lasso	4	0.08	6.1e-07	11.5	-12.0	2.6e-33	-0.96	0.00	1.00	TRUE
1	GTEx	Brain Cerebellar Hemisphere	DCST2	0.45	0.10	lasso	6	0.16	6.6e-05	-3.4	8.6	6.8e-18	0.75	0.01	0.96	TRUE
2	GTEx	Brain Nucleus accumbens basal ganglia	DCST2	0.28	0.04	lasso	5	0.13	2.0e-04	11.5	7.7	1.0e-14	0.69	0.02	0.90	TRUE
5	GTEx	Esophagus Mucosa	MUC1	0.17	0.20	lasso	4	0.18	5.6e-12	-6.7	-6.3	2.6e-10	-0.12	1.00	0.00	TRUE
20	The Cancer Genome Atlas	Prostate Adenocarcinoma	GBA	0.05	0.01	lasso	2	0.01	2.3e-02	7.1	-6.2	4.5e-10	-0.07	0.00	0.78	TRUE
16	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	MUC1	0.04	0.01	enet	4	0.02	1.3e-03	-6.7	-5.8	5.4e-09	-0.15	0.02	0.52	TRUE
3	GTEx	Breast Mammary Tissue (Female)	FAM189B	0.05	-0.01	lasso	2	0.00	4.8e-01	-5.8	5.8	8.6e-09	0.09	0.04	0.06	TRUE
14	The Cancer Genome Atlas	Bladder Urothelial Carcinoma	TRIM46	0.03	0.00	blup	33	0.02	3.6e-03	-6.7	-5.3	1.4e-07	-0.11	0.02	0.26	TRUE
17	The Cancer Genome Atlas	Head and Neck Squamous Cell Carcinoma	RAG1AP1	0.07	0.00	blup	76	0.00	2.9e-01	-2.4	-5.2	1.7e-07	-0.17	0.02	0.11	TRUE
19	The Cancer Genome Atlas	Lung Squamous Cell Carcinoma	ZBTB7B	0.05	0.06	lasso	2	0.05	1.8e-06	11.5	-11.5	1.6e-30	-1.00	0.00	1.00	FALSE
6	GTEx	Pancreas	RP11-263K19.4	0.22	0.06	enet	23	0.05	3.1e-03	1.9	-6.9	3.9e-12	-0.43	0.06	0.49	FALSE
15	The Cancer Genome Atlas	Colon Adenocarcinoma	ADAM15	0.15	0.02	blup	49	0.08	1.4e-05	7.1	-6.9	6.6e-12	-0.34	0.03	0.04	FALSE
12	NTR	Blood	ZBTB7B	0.02	0.02	lasso	1	0.01	5.4e-05	6.5	6.5	6.4e-11	0.67	0.87	0.03	FALSE
13	ROSMAP	Brain Pre-frontal Cortex	SLC50A1	0.06	0.02	bslmm	331	0.03	4.3e-05	-6.7	-6.5	6.7e-11	-0.27	0.64	0.05	FALSE
18	The Cancer Genome Atlas	Kidney Renal Papillary Cell Carcinoma	ADAM15	0.09	0.00	blup	49	0.02	3.6e-02	-1.1	-6.5	8.6e-11	-0.43	0.01	0.09	FALSE
4	GTEx	Esophagus Mucosa	ADAM15	0.11	0.02	enet	16	0.04	1.5e-03	-5.7	-6.2	5.1e-10	-0.43	0.13	0.78	FALSE
9	GTEx	Testis	MUC1	0.20	0.02	lasso	7	0.07	7.5e-04	-6.8	-5.5	3.4e-08	-0.11	0.27	0.05	FALSE
11	METSIM	Adipose	DCST2	0.04	0.04	enet	12	0.04	4.3e-07	-4.1	5.3	9.1e-08	0.47	0.85	0.12	FALSE
7	GTEx	Skin Not Sun Exposed Suprapubic	GBAP1	0.15	0.06	lasso	4	0.06	3.6e-04	-6.8	5.3	1.1e-07	0.11	0.54	0.04	FALSE
10	GTEx	Thyroid	DCST2	0.16	0.12	lasso	2	0.11	6.4e-09	-3.4	5.3	1.4e-07	0.53	0.39	0.61	FALSE