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Traits
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Traits
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Arm fat-free mass (left)
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chr17:4,488,884-6,031,861
Best TWAS P=6.27e-09 · Best GWAS P=5.51e-08 conditioned to 0.136
4.4M
4.6M
4.8M
5M
5.2M
5.4M
5.6M
5.8M
6M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
5
The Cancer Genome Atlas
Glioblastoma Multiforme
RABEP1
0.23
0.13
blup
79
0.15
3.4e-05
4.7
-5.8
6.3e-09
-0.77
0.05
0.85
TRUE
3
ROSMAP
Brain Pre-frontal Cortex
RPAIN
0.06
0.06
lasso
3
0.06
3.1e-08
5.4
-5.6
2.1e-08
-0.98
0.00
1.00
FALSE
4
The Cancer Genome Atlas
Glioblastoma Multiforme
NUP88
0.12
0.07
enet
12
0.09
1.2e-03
4.6
-5.5
4.0e-08
-0.78
0.02
0.67
FALSE
1
GTEx
Esophagus Gastroesophageal Junction
RABEP1
0.19
-0.01
lasso
13
0.00
4.2e-01
4.6
-5.3
1.4e-07
-0.82
0.03
0.79
FALSE
2
GTEx
Esophagus Muscularis
RABEP1
0.13
0.09
lasso
10
0.10
2.1e-06
5.4
-5.2
2.3e-07
-0.94
0.02
0.98
FALSE