Best TWAS P=1.91e-08 · Best GWAS P=1.31e-07 conditioned to 0.0359
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | FEZ2 | 0.16 | 0.24 | lasso | 2 | 0.22 | 1.3e-26 | 5.1 | -5.2 | 2.2e-07 | -0.97 | 0.01 | 0.99 | FALSE |
| 2 | GTEx | Adipose Subcutaneous | AC007401.1 | 0.10 | 0.02 | lasso | 4 | 0.02 | 5.4e-03 | 4.8 | 5.3 | 8.9e-08 | 0.87 | 0.05 | 0.89 | FALSE |
| 3 | GTEx | Artery Tibial | CRIM1 | 0.10 | 0.04 | lasso | 4 | 0.05 | 1.4e-04 | 4.8 | -5.3 | 1.1e-07 | -0.86 | 0.04 | 0.94 | FALSE |
| 4 | GTEx | Spleen | FEZ2 | 0.42 | 0.16 | enet | 25 | 0.17 | 3.9e-05 | 4.0 | 5.6 | 1.9e-08 | 0.66 | 0.08 | 0.73 | TRUE |