Best TWAS P=9.4e-09 · Best GWAS P=3.01e-09 conditioned to 0.027
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | PPP3R1 | 0.25 | 0.22 | lasso | 4 | 0.26 | 5.4e-20 | -5.3 | -5.7 | 1.3e-08 | 0.50 | 0.11 | 0.89 | FALSE |
| 2 | GTEx | Artery Tibial | RP11-474G23.2 | 0.17 | 0.14 | lasso | 3 | 0.12 | 2.3e-09 | -5.3 | -5.6 | 1.6e-08 | 0.45 | 0.11 | 0.89 | FALSE |
| 3 | METSIM | Adipose | PNO1 | 0.10 | 0.12 | enet | 23 | 0.12 | 1.4e-17 | -5.8 | -5.4 | 6.7e-08 | 0.97 | 0.01 | 0.99 | FALSE |
| 4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | WDR92 | 0.04 | 0.01 | blup | 49 | 0.01 | 7.9e-03 | -5.3 | -5.7 | 9.4e-09 | 0.80 | 0.01 | 0.62 | TRUE |