[Hub]/) : Traits : Arm predicted mass (left) :

chr7:70,996,097-73,789,730

Best TWAS P=6.02e-16 · Best GWAS P=3.14e-16 conditioned to 0.0134

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex DNAJC30 0.13 0.07 enet 32 0.07 2.7e-09 5.65 5.9 4.4e-09 0.24 1.00 0.00 TRUE
2 GTEx Adipose Subcutaneous MLXIPL 0.11 0.07 enet 16 0.07 1.6e-06 7.26 7.9 3.5e-15 0.88 0.05 0.95 FALSE
3 GTEx Adipose Visceral Omentum MLXIPL 0.16 0.02 lasso 3 0.03 7.8e-03 7.13 7.6 3.2e-14 0.81 0.14 0.84 FALSE
4 GTEx Adipose Visceral Omentum NSUN5 0.07 0.03 enet 11 0.04 4.0e-03 7.55 6.5 8.1e-11 0.71 0.01 0.84 FALSE
5 GTEx Cells Transformed fibroblasts MLXIPL 0.13 0.06 enet 6 0.09 2.2e-07 7.76 8.0 1.0e-15 0.82 0.07 0.92 FALSE
6 GTEx Heart Left Ventricle MLXIPL 0.14 0.00 enet 24 0.01 1.3e-01 0.15 5.5 4.2e-08 0.52 0.16 0.20 FALSE
7 GTEx Lung MLXIPL 0.10 0.07 enet 14 0.07 6.3e-06 7.26 5.8 6.5e-09 0.65 0.21 0.50 FALSE
8 GTEx Skin Not Sun Exposed Suprapubic MLXIPL 0.11 0.11 lasso 3 0.06 2.7e-04 7.76 7.7 1.7e-14 0.84 0.05 0.92 FALSE
9 GTEx Skin Sun Exposed Lower leg MLXIPL 0.12 0.09 lasso 4 0.06 6.1e-06 7.75 7.9 2.8e-15 0.86 0.06 0.94 FALSE
10 GTEx Spleen NCF1B 0.22 0.10 enet 9 0.08 5.1e-03 7.46 -7.7 2.1e-14 -0.62 0.04 0.35 FALSE
11 GTEx Testis MLXIPL 0.10 0.00 lasso 3 0.00 3.3e-01 5.37 7.2 4.8e-13 0.66 0.05 0.21 FALSE
12 GTEx Testis VPS37D 0.15 0.01 lasso 5 0.03 2.7e-02 -4.89 -5.3 1.3e-07 -0.24 0.13 0.05 FALSE
13 GTEx Thyroid MLXIPL 0.23 0.14 lasso 7 0.15 2.1e-11 7.26 8.1 6.0e-16 0.83 0.09 0.91 TRUE
14 METSIM Adipose BCL7B 0.10 0.02 enet 20 0.05 1.2e-07 7.13 5.6 2.7e-08 0.66 0.02 0.98 FALSE
15 METSIM Adipose MLXIPL 0.12 0.14 lasso 4 0.13 1.8e-19 7.53 8.0 8.7e-16 0.80 0.22 0.78 FALSE
16 The Cancer Genome Atlas Breast Invasive Carcinoma MLXIPL 0.06 0.05 lasso 2 0.05 5.1e-10 7.54 7.2 7.6e-13 0.67 0.01 0.99 FALSE
17 The Cancer Genome Atlas Lung Adenocarcinoma MLXIPL 0.04 0.03 lasso 1 0.02 2.3e-03 7.54 7.5 4.9e-14 0.67 0.01 0.85 FALSE
18 The Cancer Genome Atlas Prostate Adenocarcinoma MLXIPL 0.08 0.05 enet 4 0.05 5.3e-06 7.54 6.4 1.3e-10 0.64 0.01 0.97 FALSE
19 The Cancer Genome Atlas Skin Cutaneous Melanoma CALN1 0.37 0.04 enet 10 0.25 3.1e-07 -6.43 5.2 1.7e-07 0.02 0.01 0.96 TRUE
20 The Cancer Genome Atlas Thyroid Carcinoma BCL7B 0.05 0.01 blup 5 0.03 1.3e-03 7.54 -6.7 1.8e-11 -0.38 0.00 0.63 FALSE